ID   A0A1M6YW65_9BACT        Unreviewed;      1271 AA.
AC   A0A1M6YW65;
DT   15-MAR-2017, integrated into UniProtKB/TrEMBL.
DT   15-MAR-2017, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE            EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
GN   ORFNames=SAMN05720469_1493 {ECO:0000313|EMBL:SHL22370.1};
OS   Fibrobacter intestinalis.
OC   Bacteria; Fibrobacterota; Fibrobacteria; Fibrobacterales; Fibrobacteraceae;
OC   Fibrobacter.
OX   NCBI_TaxID=28122 {ECO:0000313|EMBL:SHL22370.1, ECO:0000313|Proteomes:UP000184275};
RN   [1] {ECO:0000313|Proteomes:UP000184275}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UWOS {ECO:0000313|Proteomes:UP000184275};
RA   Varghese N., Submissions S.;
RL   Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FRAW01000049; SHL22370.1; -; Genomic_DNA.
DR   RefSeq; WP_073306192.1; NZ_JAQYFD010000022.1.
DR   AlphaFoldDB; A0A1M6YW65; -.
DR   Proteomes; UP000184275; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0003724; F:RNA helicase activity; IEA:InterPro.
DR   CDD; cd17917; DEXHc_RHA-like; 1.
DR   CDD; cd18791; SF2_C_RHA; 1.
DR   Gene3D; 1.20.120.1080; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR002464; DNA/RNA_helicase_DEAH_CS.
DR   InterPro; IPR048333; HA2_WH.
DR   InterPro; IPR007502; Helicase-assoc_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR024590; HrpA_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010222; RNA_helicase_HrpA.
DR   NCBIfam; TIGR01967; DEAH_box_HrpA; 1.
DR   PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR   PANTHER; PTHR18934:SF83; PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE DHX16; 1.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF11898; DUF3418; 1.
DR   Pfam; PF21010; HA2_C; 1.
DR   Pfam; PF04408; HA2_N; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   Pfam; PF07717; OB_NTP_bind; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00847; HA2; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS00690; DEAH_ATP_HELICASE; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Helicase {ECO:0000313|EMBL:SHL22370.1};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   mRNA processing {ECO:0000256|ARBA:ARBA00022664};
KW   mRNA splicing {ECO:0000256|ARBA:ARBA00023187};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT   DOMAIN          25..186
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          215..384
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
SQ   SEQUENCE   1271 AA;  145258 MW;  9EF4BB28DFD52EED CRC64;
     MALDFLKAPI EYPDLPVVKK REEFLELLKN HQVVIVKADT GSGKSTQVPK FLLESGLAEK
     GRIGVTEPRR LAAMSIADRL REELKDESLV STRIRFLEEG PKDAPLKVMT DGILLQEFRR
     DRLFQMYSAI LIDEAHERSL NIDILLGIFK DVLRNRPDFR LVIASATLDA KLFEKFYENS
     AVLEAEGRMF PVQVVFADPQ QNDSKSRGDS GLVEEARDAI IALEETVGKD NLLCFLPTER
     DIQDLQAELL SKMDESKFEI LPLFGRMSPQ EQKRVFKNSG KVRIVLATNI AETSLTIPGI
     AYVVDSGMAR VSRYSPQNRI QGLPVEKISQ ASARQRTGRA GRVKPGICVR LYTQEDFESR
     EEFTEPEIRR SNLSNVVLQL RSLGLSVEDF PFIQPPPRSA FRGAYKTLFE LGALSGVARD
     ARVTPLGIEM SHLPMDATLS AVLLRARRLG VLQPAIIVCS ALSIQDPRLY PSDDEGREKA
     RRKHKSLGGH KSDFLCYLAE WNAFCREWNG TSWNSLRKYC EKNYLHFLRC REWMDLYEQF
     SRILKTHFES YVCPFNSFHR DSLHIALLSG FLGGVAQRDR DNGCYRLVGG KDAYLFPGSD
     LAGKFPEFVV SAEVRETSRV FLNKSAEILP EWIIKVAKDF CSYRWFDPKW NSVRGFVEAL
     EEVSFRGMVL SRSRRVDYGR VDAKEAARIF FLEAVVEGDM PTPFPFMEHN QRVLSALRAT
     EARQRRWGIC PSEDLQVDYL MDRAPGVFSL QTLKDFIEKN SDKALRYNEA DWISASEAGV
     EHIEAFHNNP VMDALHRKKI TQILEDKKNA KLGGVVEFEK ILNRQIRAEL VFDSSKSWDG
     LSLEIPADFL PQLSPAILAH EILKWRFWIL ESFLRELPKS ERKRLDSKKE ELDDSFVDAL
     ERNPQKSPLI SLYEAYRNWG ETEGSLPVLN PQNEHHLRLH LSIYSSAYSE KFSLELSPEW
     GVCTFFDAVR ALVSPCALSL SVLGVAYAWC PEGVRAMSLS EAEFWQKFYR RISGVGVDDS
     PLKSLFESRF VFLNRREEST FALRSLLAMT KEEKEKFGIE ILELSLPRFS GIEFARSHKV
     RSFSDISSHR TNEENASREG LLRFVSDSAY LGVSAFVKAW DVFREAFAGF RKGAKVSDSL
     LRLASVLSAE DSLYFRIRRI AAFLQGEIFR ENSGEEMALP LPSAKSFRES FSPYFSGRFL
     KEHELKKARE ALACAEKART ESERFESALV LQILLENFEL LRFKRSILAQ APEEKVEMSD
     LLKLRERFKN R
//