ID A0A1Y2HI24_9FUNG Unreviewed; 868 AA.
AC A0A1Y2HI24;
DT 30-AUG-2017, integrated into UniProtKB/TrEMBL.
DT 30-AUG-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
GN ORFNames=BCR44DRAFT_1480064 {ECO:0000313|EMBL:ORZ33343.1};
OS Catenaria anguillulae PL171.
OC Eukaryota; Fungi; Fungi incertae sedis; Blastocladiomycota;
OC Blastocladiomycetes; Blastocladiales; Catenariaceae; Catenaria.
OX NCBI_TaxID=765915 {ECO:0000313|EMBL:ORZ33343.1, ECO:0000313|Proteomes:UP000193411};
RN [1] {ECO:0000313|EMBL:ORZ33343.1, ECO:0000313|Proteomes:UP000193411}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PL171 {ECO:0000313|EMBL:ORZ33343.1,
RC ECO:0000313|Proteomes:UP000193411};
RG DOE Joint Genome Institute;
RA Mondo S.J., Dannebaum R.O., Kuo R.C., Labutti K., Haridas S., Kuo A.,
RA Salamov A., Ahrendt S.R., Lipzen A., Sullivan W., Andreopoulos W.B.,
RA Clum A., Lindquist E., Daum C., Ramamoorthy G.K., Gryganskyi A., Culley D.,
RA Magnuson J.K., James T.Y., O'Malley M.A., Stajich J.E., Spatafora J.W.,
RA Visel A., Grigoriev I.V.;
RT "Pervasive Adenine N6-methylation of Active Genes in Fungi.";
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC Evidence={ECO:0000256|ARBA:ARBA00001556};
CC -!- SIMILARITY: Belongs to the DEAD box helicase family. DEAH subfamily.
CC PRP16 sub-subfamily. {ECO:0000256|ARBA:ARBA00038040}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ORZ33343.1}.
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DR EMBL; MCFL01000036; ORZ33343.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Y2HI24; -.
DR STRING; 765915.A0A1Y2HI24; -.
DR OrthoDB; 3682876at2759; -.
DR Proteomes; UP000193411; Unassembled WGS sequence.
DR GO; GO:1990904; C:ribonucleoprotein complex; IEA:UniProt.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd18791; SF2_C_RHA; 1.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR InterPro; IPR002464; DNA/RNA_helicase_DEAH_CS.
DR InterPro; IPR048333; HA2_WH.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR PANTHER; PTHR18934:SF91; PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE PRP16; 1.
DR Pfam; PF21010; HA2_C; 1.
DR Pfam; PF04408; HA2_N; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF07717; OB_NTP_bind; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00847; HA2; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00690; DEAH_ATP_HELICASE; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:ORZ33343.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000193411}.
FT DOMAIN 192..317
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 332..513
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 15..48
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 775..802
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 868 AA; 97160 MW; FBEF52052C88899D CRC64;
MDYDHNPFAG YELAELAAPQ PDAQPVKKRP SQRALNAARD TDKWESNRLL TSGLAQRLAA
GDDDDSDTED AQDQVHVMVY TKQLETVQVV RDPTSDMAVV ARQGSGVVRM RRAEGERKKQ
ARERVDVKGT VLADAQASDQ HQLVQVKTEQ PAAPSSEAVS EFALTKSIKS QREYLPVYSV
REDLLSAIRE NQIVVVLTQY LCESGYAAGG AMIGCTQPRR VAAMSVAKRV AEEMGVELGK
QVGYTIRFED MTTPGVTQIR YMTDGVLLRE LLLDQDLDKY SCIIMDEAHE RALNTDVLMG
IIKRVVARRR DLKLIFSRFF GNVPVFEIPG RTFPDYVESA VKQTLQIHLT HPPGDVLIFM
TGQEDIEATC AILADRLDDM HNPPPLDILP IYSQMPADLQ AKIFNASPHR KVVVATNIAE
TSLTIDGIKY VIDSGFCKLK YYNAKIGMDA LQITPISQAN ANQRSGRAGR TGPGTCYRMY
TEAAFNDELY PNTIPEIQRT NLANVVLLLK SMGVENLLHF EFMDPPPQDV ILNSMYQLWI
LGSLGNTGDL TPMGSKMVSF PLDPSLAKML LVAAELGCTQ EMVVIVSMLS VPTVFYRPKE
RAEEADAARE RFFVAESDHL TLLHVYLQWR GNGMRDAWCI KNFVQPRAMR RAEEVRVQLA
DILKSQQIPM TSCGKDWDVL RKCICSAYFH QAARLKSIGE YVNLRSGLPC HLHPTSALAG
LGYTPNYIVY HELVLTSKEY VHYVTAVDPH WLAELGPMFF SVRDRGFGFR EKREIERVER
RNLEWEAQIA AERKAIEEER KRAGSIGKPI RRRKRLEIND PTWGRAGRRR QVSGEGSRHG
FGWGGGSGIR FGGCGSRRGR ELDGGCGG
//
