ID A0A210PGL2_MIZYE Unreviewed; 2026 AA.
AC A0A210PGL2;
DT 27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT 27-SEP-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
GN ORFNames=KP79_PYT13850 {ECO:0000313|EMBL:OWF35619.1};
OS Mizuhopecten yessoensis (Japanese scallop) (Patinopecten yessoensis).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC Autobranchia; Pteriomorphia; Pectinida; Pectinoidea; Pectinidae;
OC Mizuhopecten.
OX NCBI_TaxID=6573 {ECO:0000313|EMBL:OWF35619.1, ECO:0000313|Proteomes:UP000242188};
RN [1] {ECO:0000313|Proteomes:UP000242188}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PY_sf001 {ECO:0000313|Proteomes:UP000242188};
RX PubMed=28812685; DOI=10.1038/s41559-017-0120;
RA Wang S., Zhang J., Jiao W., Li J., Xun X., Sun Y., Guo X., Huan P.,
RA Dong B., Zhang L., Hu X., Sun X., Wang J., Zhao C., Wang Y., Wang D.,
RA Huang X., Wang R., Lv J., Li Y., Zhang Z., Liu B., Lu W., Hui Y., Liang J.,
RA Zhou Z., Hou R., Li X., Liu Y., Li H., Ning X., Lin Y., Zhao L., Xing Q.,
RA Dou J., Li Y., Mao J., Guo H., Dou H., Li T., Mu C., Jiang W., Fu Q.,
RA Fu X., Miao Y., Liu J., Yu Q., Li R., Liao H., Li X., Kong Y., Jiang Z.,
RA Chourrout D., Li R., Bao Z.;
RT "Scallop genome provides insights into evolution of bilaterian karyotype
RT and development.";
RL Nat. Ecol. Evol. 1:120-120(2017).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC Evidence={ECO:0000256|ARBA:ARBA00001556};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OWF35619.1}.
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DR EMBL; NEDP02076717; OWF35619.1; -; Genomic_DNA.
DR STRING; 6573.A0A210PGL2; -.
DR Proteomes; UP000242188; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR GO; GO:0051321; P:meiotic cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0031047; P:regulatory ncRNA-mediated gene silencing; IEA:UniProtKB-KW.
DR GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
DR CDD; cd20435; Tudor_TDRD12_rpt2; 1.
DR Gene3D; 2.30.30.140; -; 3.
DR Gene3D; 2.40.50.90; -; 3.
DR Gene3D; 2.60.40.790; -; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR007052; CS_dom.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR008978; HSP20-like_chaperone.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR035437; SNase_OB-fold_sf.
DR InterPro; IPR002999; Tudor.
DR PANTHER; PTHR22655:SF2; ATP-DEPENDENT RNA HELICASE TDRD12-RELATED; 1.
DR PANTHER; PTHR22655; UNCHARACTERIZED; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00567; TUDOR; 3.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00333; TUDOR; 3.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF49764; HSP20-like chaperones; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 3.
DR PROSITE; PS51203; CS; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS50304; TUDOR; 3.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW Differentiation {ECO:0000256|ARBA:ARBA00022782};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Meiosis {ECO:0000256|ARBA:ARBA00023254};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000242188};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW RNA-mediated gene silencing {ECO:0000256|ARBA:ARBA00023158};
KW Spermatogenesis {ECO:0000256|ARBA:ARBA00022871}.
FT DOMAIN 56..118
FT /note="Tudor"
FT /evidence="ECO:0000259|PROSITE:PS50304"
FT DOMAIN 634..822
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 847..1008
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT DOMAIN 1119..1183
FT /note="Tudor"
FT /evidence="ECO:0000259|PROSITE:PS50304"
FT DOMAIN 1359..1416
FT /note="Tudor"
FT /evidence="ECO:0000259|PROSITE:PS50304"
FT DOMAIN 1846..1934
FT /note="CS"
FT /evidence="ECO:0000259|PROSITE:PS51203"
FT REGION 239..260
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 432..510
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1954..1982
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1995..2026
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 432..459
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 472..509
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2026 AA; 228064 MW; 26C2F4CE0BE8D64B CRC64;
MSDLVDIEIT KVKSPALFYA KVVRDLESSE GLSFQQLEKS INDFFNSESL YLPNYIPNEG
DICIGRRVSD RCWCRVQVKG VLSRRSGPEG RCFFLDYGIS DFIPLKWFRK ASSDYLQVPY
QVKKFCLYGV KALTLAVETE DLTFKEVVSE FWDTSAVTLM NQVVKESHST KARFRCVDRD
DVHHVDIYFI SPKQTIWLNE EFVTLKYAAW CNPEQTLADS GEAVIQKLLK HTKTLESSLY
GDGGNRTKKP LSGSCSDTES GRRTLFSPVK HSLNSTVPVV ERMKRRGIHH SVADQITNSI
SNLSSQNVSG TLAEGDHVKK SQKNDLKRKP FTITEIRERK KLCEPSVCSD SEIVYNSSPF
HQKSTNSIQA LTSVGILTSS GTPVSPICSS ALDKSIERLS MSPASSNSSL TSPIVSKNFM
LGRLISVISP KKKESTATND LGPTKTSIKT NTSKLLHSEL SLPLTPARLP KSAMRSSASE
SDPDNSRVQV SRQISTSSSK SSGSASSEED KLVSDIKKSI LKKSSSSVLL NDKPSVRFRD
SEALAETHAK KTQMMGRLTG KKLLDKLCVG VGSHSMGKKP GEEPNLNDDG VLVHSEDPLK
PIYNIHDTPL DPIIREGLDN YGIVAPKFVQ CYTWPALLRG RNVVGISPSG SGKTFAYLAP
LLTDLLKPSN YKDIPTGNGP YAIILVPFWK SAQMVYDVTK ILLGNSRSFR VLVAYGGGNE
ENQVVPLING CELLITTPRS LSRLLQQKYT HLERLCHVVI DDAEIVLEEF REEIQDFMIS
YSRVVEEHVE RSAPREVLVF SSRWCNMVNS FIDAFIPDPT LIITSRFEAA IYGRVKQIPL
LWRTDQLVSQ FLELVNSLAQ ENSKMIIFCS NVNTTLHIHK LLKSRSLYSL LTHDKMDTLM
LEQIGGEWEG PSDKGKILIC TDESVEELKI VDATAIVHYE LPSSKTKFGN RLSTMSKYYH
NSSSKEKINI DPTSYILITE DSGRQVETIL QLLKRTKSKI PRNLYSMVMG LNQEKNCDGD
KDLCVALKAY GSCRYQNKCP ARHALLPEVD CKATQQPLNS GEVKVLVTNV VDASHYFVRL
LEHRPPTGDK VDTSMTMLDL RFKMAEWFGD LQHRSKYSSL CIGEMCAVSE DEETYHRVKV
CDITGVNSPG DRIKAELMFV DDGRKSFVSP NKLYNLPPHL RDVPYQALEV FICRVQPVDL
DEKWTSKASM FVYDLLDKKT MDGRIVLRIG NTLWLDPLVE RVYLSDLHAY CTNLFVRSEL
LKNGFAVNNS NHMQLLYDLC KGKIEVPKLN LQSDRSEKKN EVEILPESKE YHDVHLSAVN
SPTLIYLQRS DTFKLLEKMN DEINERMKNE ELTGMKIISL KTGSVCLGKW DDMWYRVRIL
EELEDNMVEV FHVDFGDSET VSRDSLQKIP QEFLELPFQA IEAGLSYVAP QGETWEEAAG
DLIWDLAHFV TNDMKVLAAK VVTKQYAMNA GNHKYYVELY DRSTYFDVNL ALELVWSGYA
TPTEDSPYHV KELFSPPQEK QFFTIPILKL LDLCSQIYWG KGDCKAEAAG KEILKMVTTC
AKSKPLNLVA YGGLKAIIKL IGRVGYEDIH RCLLDSLTTA ASKHDRICEE IVEQDGCVGI
VNSLERTNKP WLQEQVLVAM GKLLDTSIRF MPCFEDERVV LTLCELLDST DKSKVQTALC
YTLRKMCRLS EAVLLMTFDN KVCSRLVNCL GEGEKEVDPD VTTAALELLD TLLEKDEKNE
DSLTKPKVVK CVVGTLKGTE DETCILCGLK YCKYYGNLNR RNKTTLLQLE LVPVLNKLQS
LTHLSSVIHD MCLDLKSSLI VNVQSSQTIK NTPIDQSKAA SSQVDSILPQ VLWSENIFTV
RLSIKVVGVN PKSDPVQTTE NSICFSALVD GKVYVVEYIL YDSILPARSQ VKVSSGEVTV
ILRKNQKGRW PRLIKLKAKP ANLMYDFDRY EDSSSAEEEE EDCGEDVPGP ARKSKKQRLP
MGISAERQQQ IMLRHRLEQD GSLTSSDENV DIPKEYNPYD IFDAEH
//
