ID A0A251QZR8_PRUPE Unreviewed; 1340 AA.
AC A0A251QZR8;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
GN ORFNames=PRUPE_1G193500 {ECO:0000313|EMBL:ONI29331.1};
OS Prunus persica (Peach) (Amygdalus persica).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Rosales; Rosaceae; Amygdaloideae; Amygdaleae; Prunus.
OX NCBI_TaxID=3760 {ECO:0000313|EMBL:ONI29331.1, ECO:0000313|Proteomes:UP000006882};
RN [1] {ECO:0000313|EMBL:ONI29331.1, ECO:0000313|Proteomes:UP000006882}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nemared {ECO:0000313|Proteomes:UP000006882};
RX PubMed=23525075; DOI=10.1038/ng.2586;
RA Verde I., Abbott A.G., Scalabrin S., Jung S., Shu S., Marroni F.,
RA Zhebentyayeva T., Dettori M.T., Grimwood J., Cattonaro F., Zuccolo A.,
RA Rossini L., Jenkins J., Vendramin E., Meisel L.A., Decroocq V.,
RA Sosinski B., Prochnik S., Mitros T., Policriti A., Cipriani G., Dondini L.,
RA Ficklin S., Goodstein D.M., Xuan P., Del Fabbro C., Aramini V., Copetti D.,
RA Gonzalez S., Horner D.S., Falchi R., Lucas S., Mica E., Maldonado J.,
RA Lazzari B., Bielenberg D., Pirona R., Miculan M., Barakat A., Testolin R.,
RA Stella A., Tartarini S., Tonutti P., Arus P., Orellana A., Wells C.,
RA Main D., Vizzotto G., Silva H., Salamini F., Schmutz J., Morgante M.,
RA Rokhsar D.S.;
RT "The high-quality draft genome of peach (Prunus persica) identifies unique
RT patterns of genetic diversity, domestication and genome evolution.";
RL Nat. Genet. 45:487-494(2013).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC Evidence={ECO:0000256|ARBA:ARBA00001556};
CC -!- SIMILARITY: Belongs to the DEAD box helicase family. DEAH subfamily.
CC {ECO:0000256|ARBA:ARBA00008792}.
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DR EMBL; CM007651; ONI29331.1; -; Genomic_DNA.
DR STRING; 3760.A0A251QZR8; -.
DR EnsemblPlants; ONI29331; ONI29331; PRUPE_1G193500.
DR Gramene; ONI29331; ONI29331; PRUPE_1G193500.
DR OrthoDB; 5490433at2759; -.
DR Proteomes; UP000006882; Chromosome g1.
DR GO; GO:0005730; C:nucleolus; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IBA:GO_Central.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR GO; GO:0003724; F:RNA helicase activity; IEA:UniProtKB-EC.
DR GO; GO:0000462; P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IBA:GO_Central.
DR CDD; cd17982; DEXHc_DHX37; 1.
DR CDD; cd18791; SF2_C_RHA; 1.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR002464; DNA/RNA_helicase_DEAH_CS.
DR InterPro; IPR048333; HA2_WH.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR PANTHER; PTHR18934:SF99; ATP-DEPENDENT RNA HELICASE DHX37-RELATED; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF21010; HA2_C; 1.
DR Pfam; PF04408; HA2_N; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF07717; OB_NTP_bind; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00847; HA2; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00690; DEAH_ATP_HELICASE; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000006882}.
FT DOMAIN 287..479
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 654..837
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 130..157
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 673..702
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 50..77
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 134..156
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1340 AA; 150459 MW; 0CE33D20A0FAD927 CRC64;
MRSKLDFPME NCAQHMDLSL GGGDSNTLIL PAKRRNKRKG TNQDCEKLNQ RKATMISKSQ
QRKLKKLEEE KEKSLSISKS IEALEKYKLP EGAHSLLQSS KNIGKVESKK EKRRKAVLFS
KAGFGVPLTD QPFKKIDSES ESESEPELEK TQSRSDLCKN DQVQSKIVPA AIQKNTFISL
DGRGPGVNGG TAADSPYKNA ISNKHDTSLR EDINILPTSS VNDDSQSMKM DKVKETPNVN
FSRTSKLSNS PMPRSLIAPT IVHVSRPEEV ENARKDLPIV MMEQEIMEAV NDHSTVIICG
ETGCGKTTQV PQFLFEAGFG SSFSCVRSGI IGVTQPRRVA VLATAKRVAY ELGLHLGQEV
GFQVRYDKRI GESCSIKFMT DGILLRELQN DFLLKRYSVI IIDEAHERSL NTDILIGMLS
RVIRAREEKY AEQQREVLSG RTISTGQQIF PLKLVLMSAT LRVEDFMSGR KLFRNPPPVV
EVPTRQFPVT IYFSSRTKEE DYIGQACKKV LAIHKRLPRG GILVFVTGQK EVEYLCRKLR
RVSKEQYKKT SEGDIRSDVT EVSERSSTEE IDMKEINEAF EVHGNSADHQ TDRFSYNDED
QFDIDDDELD DSYDSETESE LEIIGDYGNS LIRASPEIDG DVENVLGEEG GITQLKAAFE
ALDAKTSFNF NSDEKQPISV TPNACPNQSN PSMGKKSGVE ENTSPGTLHV LPLYAMLHAK
DQLRVFEEVR EGERLVVVAT NVAETSLTIP GIKYVVDTGR EKVKSYNSSN GMETYEVQWI
SKASAAQRAG RAGRTGPGYC YRLYSSAAYS NIFPDFSPAE ISKVPVDGVV LYMKSMNIDK
VSNFPFPTPP EGAALDEAER CLKILQALDS NGRLTPLGKA MADFPMSPRH SRMLLTVIQI
MSKEKSYSRA NLVLAYAVAA AAALSLSNPF VRQFEDSHTK SQDLDEDGNS SGTVNIEVMD
KQEKLRRKKL KETVKMFREK FSNPSSDALS VAYALQCYEL SESPVEFCNV NALHPKTMEE
MSKLRKQLLQ LVFNQSGVSG GEKDFSWIFG SLKDVENVWR VSHDKNPLLL YEEELLGQAI
CAGWADRVAK RIRGSSGLSL GDKKVHAVWY QACMVKEIVF LHRWSSVSNS APEFLVYSEL
IQTRHPYMHG VTSVKSEWLV EYARSICTFS APPTDTKPYY EPLTDQVLHY VIPVFGPHLW
ELPSHSIPIS NYAFRVAVFA YALLEGQVLP CLRSVRKYMA APPASVLRPE AAGQRRVGSL
LAKLNRKKID SCAILREVWK ENPKELHPEI MDWFQEGFHN NFKTLWSHML SEVILEPQDR
FPKASKREGM ISHCICREMH
//
