ID A0A2K0W5D0_GIBNY Unreviewed; 454 AA.
AC A0A2K0W5D0;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 11.
DE RecName: Full=N-acetylgalactosaminide beta-1,3-galactosyltransferase {ECO:0000256|ARBA:ARBA00012557};
DE EC=2.4.1.122 {ECO:0000256|ARBA:ARBA00012557};
GN ORFNames=FNYG_09357 {ECO:0000313|EMBL:PNP77481.1};
OS Gibberella nygamai (Bean root rot disease fungus) (Fusarium nygamai).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium fujikuroi species complex.
OX NCBI_TaxID=42673 {ECO:0000313|EMBL:PNP77481.1, ECO:0000313|Proteomes:UP000236664};
RN [1] {ECO:0000313|EMBL:PNP77481.1, ECO:0000313|Proteomes:UP000236664}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CS10214 {ECO:0000313|EMBL:PNP77481.1,
RC ECO:0000313|Proteomes:UP000236664};
RA Gardiner D.M., Obanor F., Kazan K.;
RT "Genome of Fusarium nygamai isolate CS10214.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=an N-acetyl-alpha-D-galactosaminyl derivative + UDP-alpha-D-
CC galactose = a beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-
CC galactosaminyl derivative + H(+) + UDP; Xref=Rhea:RHEA:15621,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:28257, ChEBI:CHEBI:58223,
CC ChEBI:CHEBI:66914, ChEBI:CHEBI:133470; EC=2.4.1.122;
CC Evidence={ECO:0000256|ARBA:ARBA00000862};
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- PATHWAY: Protein modification; protein glycosylation.
CC {ECO:0000256|ARBA:ARBA00004922}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004606}; Single-
CC pass type II membrane protein {ECO:0000256|ARBA:ARBA00004606}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 31 family. Beta3-Gal-T
CC subfamily. {ECO:0000256|ARBA:ARBA00006462}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PNP77481.1}.
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DR EMBL; MTQA01000127; PNP77481.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2K0W5D0; -.
DR STRING; 42673.A0A2K0W5D0; -.
DR OrthoDB; 2664045at2759; -.
DR Proteomes; UP000236664; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016757; F:glycosyltransferase activity; IEA:InterPro.
DR Gene3D; 3.90.550.50; -; 1.
DR InterPro; IPR026050; C1GALT1/C1GALT1_chp1.
DR InterPro; IPR003378; Fringe-like_glycosylTrfase.
DR InterPro; IPR003609; Pan_app.
DR PANTHER; PTHR23033:SF47; APPLE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR23033; BETA1,3-GALACTOSYLTRANSFERASE; 1.
DR Pfam; PF02434; Fringe; 1.
DR Pfam; PF00024; PAN_1; 1.
DR SUPFAM; SSF57414; Hairpin loop containing domain-like; 1.
PE 3: Inferred from homology;
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000236664};
KW Signal-anchor {ECO:0000256|ARBA:ARBA00022968};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..30
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 187..304
FT /note="Fringe-like glycosyltransferase"
FT /evidence="ECO:0000259|Pfam:PF02434"
FT DOMAIN 384..426
FT /note="Apple"
FT /evidence="ECO:0000259|Pfam:PF00024"
SQ SEQUENCE 454 AA; 51599 MW; EDE9ECA0BCACB9C7 CRC64;
MVVISRRTRR RLRSIFILIL ISIFVIYSIL PHDSAIRLAF VFNISRFFNF LRGAATNRDA
WLWKSPRYVV DLKNEVGYLI KTGYGTRHRV PEQLAAFEAT GGFLGKEGEG FLVVGDWTTV
NQTDARLIGV TVHDAIERVM ETKIRGKVDD YPRLVKYSSL QAKLQAGDEE EALKIGQSYG
WELDALKFIM GMEMIYHQLP GKKWYIILDD DTFLIRPSLE LLMGHVDYRK PQYIGNAVGD
YKARFGHGGS GILISGEAMR RLFEHPGIVQ EAYVESMTET WGDRLVATTL QKLGIYIEES
YNHHFNGEPP SITRIWGDRF CSPLLSFHGL RKPGEMRRVG ETLAKMDKPV LWHDVWQLFG
GSAMSALESR PTELTADHVG KPDEHTRSWG DVRSANACQK RCEQSGRRCL AWTYEMEIER
CHTSPWLLLG ADGATGKASG VNWPEVKPLL KGCR
//
