ID A0A2V5LAM9_9MICC Unreviewed; 1333 AA.
AC A0A2V5LAM9;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
GN Name=hrpA {ECO:0000313|EMBL:PYI68665.1};
GN ORFNames=CVV68_05000 {ECO:0000313|EMBL:PYI68665.1};
OS Arthrobacter livingstonensis.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Micrococcaceae;
OC Arthrobacter.
OX NCBI_TaxID=670078 {ECO:0000313|EMBL:PYI68665.1, ECO:0000313|Proteomes:UP000247832};
RN [1] {ECO:0000313|EMBL:PYI68665.1, ECO:0000313|Proteomes:UP000247832}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LI2 {ECO:0000313|EMBL:PYI68665.1,
RC ECO:0000313|Proteomes:UP000247832};
RA Liu Q., Xin Y.-H.;
RT "Genetic diversity of glacier-inhabiting Cryobacterium bacteria in China
RT and description of Cryobacterium mengkeensis sp. nov. and Arthrobacter
RT glacialis sp. nov.";
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PYI68665.1}.
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DR EMBL; QJVD01000004; PYI68665.1; -; Genomic_DNA.
DR OrthoDB; 9805617at2; -.
DR Proteomes; UP000247832; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:InterPro.
DR CDD; cd18791; SF2_C_RHA; 1.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR002464; DNA/RNA_helicase_DEAH_CS.
DR InterPro; IPR048333; HA2_WH.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR024590; HrpA_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR010222; RNA_helicase_HrpA.
DR NCBIfam; TIGR01967; DEAH_box_HrpA; 1.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR PANTHER; PTHR18934:SF83; PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE DHX16; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF11898; DUF3418; 1.
DR Pfam; PF21010; HA2_C; 1.
DR Pfam; PF04408; HA2_N; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF07717; OB_NTP_bind; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00847; HA2; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00690; DEAH_ATP_HELICASE; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000313|EMBL:PYI68665.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW mRNA processing {ECO:0000256|ARBA:ARBA00022664};
KW mRNA splicing {ECO:0000256|ARBA:ARBA00023187};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 21..184
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 232..407
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 203..232
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 985..1038
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 212..232
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1011..1026
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1333 AA; 147018 MW; 96D92BEAC4330BFC CRC64;
MTLTITYPAA LPVSERREDL MAAIAANQVT IIAGETGSGK TTQIPKMCVE LGLAEKGLIG
HTQPRRLAAR TVAERIASEL DVEIGAEVGF QVRFTGHVGP QTKIKIMTDG ILLAEIQRDR
LLRKYSVIII DEAHERSLNI DFILGYLRQI LPQRPDLKVI ITSATIDPQR FAEHFASADG
PAPIMEVSGR TFPVEIRYRP LSGPLSGADD DDSGTGADRH LDGGNSEEDR DPLDAVCDAV
DELSREAPGD VLVFFSGERE IRDAADALAG RIKTKPRLRD VQILPLFARL SLAEQHAVFT
PGPRRRIVLA TNVAETSLTV PGIKYVIDTG TARISRYSHR TKVQRLPIER ISQASANQRS
GRCGRVSDGI CIRLYSEEDF DARSEFTDPE ILRTNLAAVI LQMTAMGVAK GPKDVEKFPF
VQPPDSRAIT DGVTLLRELG AVNAQGGITG VGRQLSQLPV DPRLGRMIVE AAKRGVAAEV
MVLAAALTIQ DPRERPTDKQ QLATEKHKRF VDANSDFTGF LNLWRYIKEK QGELSSSAFR
RLCKAEFINY LRVREWQDLF TQLKQMAKPL GIKVSGNDID PVANHDAIHM SLLTGLLSHI
GLYDQRKREY AGARGTKFMV FPGSALFKKS PDWVMAAELV ETSRLWARVA AKFDPLWAEQ
VAPELVKRSY SEPHWSKKMG SVMAHEKVTL YGVPIVPDRR VHYGRIDPEL SREMFIQHAL
VEGDWHTNHK FFHRNQALLA EVEELETRMR RRDLRVDDEA LFEFYDGRVG SEVVSERHFD
KWWKDARHDN PALLDFDTHV VMAEEPELDE TAFPKIWTEG EFELPLSYEF HPTAPGSVPN
PSDGVTVQVP LLFLNQLHEA PFRWQIPGLR AELVTALIKS LPKSVRKNFI PAPDMGRQAA
AALAADFNPS ADPLEPSLEL ALRRLRGHVI PPGSWNWDAV PSHLRMTFQV VDKDGRILEE
GQDLAGLQAQ LAGATRRAIA EQLGATPKTT QAGRAPLGTH AAGTTAPGAP TATGGGPSSN
IPGRSVSPRD GSLGAVGPEA DTVGIRERSG LTAWSVGTVP REVRRLVSGH TVTGYPALVD
EGATAGVRIF QRQDVQESAM RGGVIRLLAL RVPSPDRYVL DHLSNTEKLT FSQNPHGSVA
ELIADCTLAT IDKLTPAELP WNEKDFNALY EVVRAELFDS VFSVTAVVER VLASKLRIDK
ALRASNSLPL ISALNDVRQQ LELLVYPGFV AKTGFAQLSQ LPRYLAAIER RLEKLPSNVA
RDGQSMAAVQ RLEDEYDDAV AALLPSQRST GGLEHVRWML EELRVSLFAV ELGTAYSVSE
KRVRAALAKA LAG
//
