ID A0A3M7QWU6_BRAPC Unreviewed; 410 AA.
AC A0A3M7QWU6;
DT 13-FEB-2019, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Guanine nucleotide-binding G(K) subunit alpha {ECO:0000313|EMBL:RNA15812.1};
DE EC=3.6.1.15 {ECO:0000313|EMBL:RNA15812.1};
GN ORFNames=BpHYR1_026450 {ECO:0000313|EMBL:RNA15812.1};
OS Brachionus plicatilis (Marine rotifer) (Brachionus muelleri).
OC Eukaryota; Metazoa; Spiralia; Gnathifera; Rotifera; Eurotatoria;
OC Monogononta; Pseudotrocha; Ploima; Brachionidae; Brachionus.
OX NCBI_TaxID=10195 {ECO:0000313|EMBL:RNA15812.1, ECO:0000313|Proteomes:UP000276133};
RN [1] {ECO:0000313|EMBL:RNA15812.1, ECO:0000313|Proteomes:UP000276133}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HYR1 {ECO:0000313|EMBL:RNA15812.1};
RX PubMed=30375419; DOI=10.1038/s41598-018-34188-y;
RA Franch-Gras L., Hahn C., Garcia-Roger E.M., Carmona M.J., Serra M.,
RA Gomez A.;
RT "Genomic signatures of local adaptation to the degree of environmental
RT predictability in rotifers.";
RL Sci. Rep. 8:16051-16051(2018).
CC -!- SUBUNIT: G proteins are composed of 3 units; alpha, beta and gamma. The
CC alpha chain contains the guanine nucleotide binding site.
CC {ECO:0000256|ARBA:ARBA00011356}.
CC -!- SIMILARITY: Belongs to the G-alpha family.
CC {ECO:0000256|ARBA:ARBA00005804}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RNA15812.1}.
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DR EMBL; REGN01004882; RNA15812.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3M7QWU6; -.
DR STRING; 10195.A0A3M7QWU6; -.
DR Proteomes; UP000276133; Unassembled WGS sequence.
DR GO; GO:0031683; F:G-protein beta/gamma-subunit complex binding; IEA:InterPro.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0007186; P:G protein-coupled receptor signaling pathway; IEA:InterPro.
DR CDD; cd00066; G-alpha; 1.
DR Gene3D; 1.10.400.10; GI Alpha 1, domain 2-like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR001019; Gprotein_alpha_su.
DR InterPro; IPR011025; GproteinA_insert.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10218; GTP-BINDING PROTEIN ALPHA SUBUNIT; 1.
DR PANTHER; PTHR10218:SF302; GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-8 SUBUNIT-RELATED; 1.
DR Pfam; PF00503; G-alpha; 2.
DR PRINTS; PR00318; GPROTEINA.
DR SMART; SM00275; G_alpha; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF47895; Transducin (alpha subunit), insertion domain; 1.
DR PROSITE; PS51882; G_ALPHA; 1.
PE 3: Inferred from homology;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Hydrolase {ECO:0000313|EMBL:RNA15812.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000276133};
KW Transducer {ECO:0000256|ARBA:ARBA00023224}.
SQ SEQUENCE 410 AA; 48434 MW; E56B0F157473C76E CRC64;
MSPTPITEDE YGLEDQSICQ RAFKSCLNSR EKKYFPSSSD PSFEQMIKIL VVGPGDSGKS
TILKQMRVIH DKNYSNEECR RYKPVIIQNI LDSTIRLVEA MDIFNINFDE KDNSANYEMI
QRCYEKLRSG DINDWNQNSE DYCNAIKSIW QDISIKSCFE KRNLFYLMDS TEYFMDNLER
ICSKQYVPIL DDILRVRQPT TAIQEYTFKI SGSYFLFVDV GGQRSERRKW INCFENVTCL
LFVASLSDYD LKMSRDELRS SNSNEDEEVN RMRDGLDLFK TLINWKKKVY HQTTRNSQKQ
ESTEVLLFGN CSIVLFLNKE DLFEEKFRRS SLKQCFKDYQ ETNSTEQAKQ FIAHKFVEAD
DTLRTSSQGR DIYWHYTFAL DKKCIETVVA SRFKNKSTFK FSSEINYHIY
//
