ID A0A482XC04_LAOST Unreviewed; 2827 AA.
AC A0A482XC04;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
GN ORFNames=LSTR_LSTR013872 {ECO:0000313|EMBL:RZF43192.1};
OS Laodelphax striatellus (Small brown planthopper) (Delphax striatella).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Paraneoptera; Hemiptera; Auchenorrhyncha; Fulgoroidea;
OC Delphacidae; Criomorphinae; Laodelphax.
OX NCBI_TaxID=195883 {ECO:0000313|EMBL:RZF43192.1, ECO:0000313|Proteomes:UP000291343};
RN [1] {ECO:0000313|EMBL:RZF43192.1, ECO:0000313|Proteomes:UP000291343}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Lst14 {ECO:0000313|EMBL:RZF43192.1};
RC TISSUE=Whole body {ECO:0000313|EMBL:RZF43192.1};
RX PubMed=29136191; DOI=.1093/gigascience/gix109;
RA Zhu J., Jiang F., Wang X., Yang P., Bao Y., Zhao W., Wang W., Lu H.,
RA Wang Q., Cui N., Li J., Chen X., Luo L., Yu J., Kang L., Cui F.;
RT "Genome sequence of the small brown planthopper, Laodelphax striatellus.";
RL Gigascience 6:1-12(2017).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC Evidence={ECO:0000256|ARBA:ARBA00001556};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RZF43192.1}.
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DR EMBL; QKKF02012883; RZF43192.1; -; Genomic_DNA.
DR STRING; 195883.A0A482XC04; -.
DR InParanoid; A0A482XC04; -.
DR Proteomes; UP000291343; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003724; F:RNA helicase activity; IEA:UniProtKB-EC.
DR GO; GO:0010468; P:regulation of gene expression; IEA:UniProt.
DR CDD; cd18791; SF2_C_RHA; 1.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 3.30.160.20; -; 5.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR002464; DNA/RNA_helicase_DEAH_CS.
DR InterPro; IPR014720; dsRBD_dom.
DR InterPro; IPR048333; HA2_WH.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR PANTHER; PTHR18934:SF119; ATP-DEPENDENT RNA HELICASE A; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF04408; HA2_N; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00358; DSRM; 6.
DR SMART; SM00847; HA2; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF54768; dsRNA-binding domain-like; 5.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00690; DEAH_ATP_HELICASE; 1.
DR PROSITE; PS50137; DS_RBD; 2.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000291343};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00266}.
FT DOMAIN 1227..1292
FT /note="DRBM"
FT /evidence="ECO:0000259|PROSITE:PS50137"
FT DOMAIN 1699..1763
FT /note="DRBM"
FT /evidence="ECO:0000259|PROSITE:PS50137"
FT DOMAIN 2072..2240
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 2312..2482
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 166..194
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 330..411
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 903..973
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1309..1339
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1410..1429
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 197..227
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 171..192
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 372..399
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 904..925
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 953..973
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2827 AA; 319027 MW; 5AB65F3AE48A1B4A CRC64;
MDASVELQAW CREQGLRIDI QKKKKLDDIN YVCKVKLKSY EFSAVGESFK QIKAEGIACQ
KLLAMLEVEK QFQIPGSILR ASNTGGKKAK SALQDFCSKR GLELEFERIK LGDPLHECIV
SVDSFDFCGS ASGPKNSVEN LACKDFLRQL HNWKNIRILK YLESPSGEGP SGFTKAKSPS
GGGSSGFSKD KSPSAFSKEA ENAFAQNNES LNAIEKQEEK NDFSKAESFL TYWSEVNDVV
TSYDFLSLQA VNQFLCLLSL ESRKVGKILL SEATATTKDT ASRLAAIKAV KYLLKGKLIT
PDQVGSIDLT VPDYDSDVLD NLQNLLSART NNYNQSEPEP NVIVEPEKSG SNLGADESQN
HNHREIESRD STTTSQEPSQ DVSNENRIDN TNIPDAQVHS NSESEDEDVV ERAPTPISWE
DILDEHTDSD RVILESQVDC RKSMGNLIGN TTLEKDHTEE IVSLKSPTLI NSNSEHTQHN
SVINVLESRV DNGKSMETHI ENRTLEKDHE QNYNDGLVTL KSQILTNSEH IQNNNDINLL
ESRMDSNSKS KHEQHHDVVE RAQTPISWED IITDENEESD KVILASQDSP SPETDEKKEI
VERSQTVTWQ TSDVLMAQFK REVEKNRGKL DCRKRKVEEF LSDWCQLNNI ALIFDYRFLE
TEKRQTIVCA FTLRSASIGN IFSTQTTAMK KYRAEKLAAM KAVTHLFQAE LITYDEIKVN
LDFSGTRQEF LDRPKNVKKN SSDASRKSML NMSNRNFFDE IIHWNAKSKL QEWCTKNGLN
LQIHDQLTAD PSPWNVEVES FDYVATGLTR DSACQDFIDH LRQDYEFEIL GYNNPLIGLQ
AWCVGHGLEM TFSRQNAELK HECKIKVDTL DFTGFGIGAD KRTAESLACQ DFIPHLEAAN
ISEESNGKFE SSTSESESSA LPCSQEPLES IPCGNGDTDI GSMDKEDSHS EADSNAVLPN
SSSQISQSVS PQNSTVSVAE SEQLIIENNG GKFEVRTLGL WNFLCYWCEM NNISLTYDYH
VINQDFLCVL YTLTLISPST GLLFSTEAPG NSTQKAKLLA AKEAIIYLLE KEFVTSKDIE
GLSLEASRND KAIIKGVRTF LSEVKTHKKK SSLGVELIQK LEKSVDSSII KKLESFVDPK
HKFYQGNEKS QLLEWCSRNG LNMKLETRKS GNNTREFHVE VESFDYVGKG KGIKRGRRGC
NLLYMACEDF IKHLEEDDKP DLSENPDPIT ALRKWCSERK LKMKPKLRIA DPGKYESRVE
VDTFDFCGTG IGTKRKSAGN LACRDFLNKL TEVGQIQDTI GETDVKVEAA PAPPEGPSFV
PILDQGSNED HETDVNQNPD QQVVTVESEK NQKYNENVVE SRNLRPQPKF KFWARNDISS
TDSEDSIVSQ DEEDLTVKSD RIQKYTENAV QSRKGWGTPQ GSSQDISCAG SEGSIVFQDE
EVVTSSEVDI KAVESESFEN SNREILVSEF KKVIEENRKK SGYQCGGVAI TFLNMWCKRN
NVDFTFDHRW QDPFWMCTMT LKYSTIGEFC SFKATSQSKK ASAKLATKFT LQYLLAEKFI
IPDENKGLNI DVSKNEMQLL ESLHYFPSNL ANQESLEVAM EPQEKSVTNV PFKKVRQDPR
KDLEAWCLKN GLKVQFSDQL ISKAIYQYNL SIKPYMHNGI GRGNEKKKAR NMACEAFINR
LPEIDKRLIL KLIFESQKTP SSALHEWCSI RGLKPVFKIQ KTAKKSRSEV KVESSDFDGT
GNAVGKTTAQ KMAAQDFLDR LKAAGKLQDM DNDINEVLDP PLSQQESHKE AVNDGDSDSD
VEILNQQVYH NWRLNISQEN DLSSEINNML KRVDLPTQNS DLNFDNCIIP FGTANIRLQQ
FFDENFINAN YIYSTDPNSM EGRHVASMKF YFRRIGRTFS ASESASTETE AMEKCAGALV
QQLYHANLID IVAKKKRKPI PPIRTPIELN VPDSVIENIK QLCIEFEVDI PDPIPINSKT
RKVLWSSNFT NHKESNATDY TLRIKYGGAK MNWNPWDVKD ITRNQSFYNM KLTKISETLK
SLQASKSQRY LFRQRLKERQ NLPIFHSKNK ILQLINDHPV TIVKGSTGSG KSTQVCQYIL
DNALEKNKGA YCNIIVIEPK RICASSLADR VAFERNEQLG QTVGYCVRFE STFPRSYGSI
LFCTPGSFIR RAESGLSGIS HIIVDEIHER GVETDYILII LRRMLESESF ASLKVILMSA
DVDVDLFSSY FGGCARITVN GKCFPVKDYF LEDCIELINF KFKDNEEETD MKLLNGKSKE
NLNSGILDSS AYSPDTLKTL AVIDEQIICP ELIEAIILWM REKKIQGSIL VFLPGWAEIK
QLSIHLHKSE NSANYCVLPL HSKIKGAEQK QVFLPVPVGK TKIILSTSLA ESSVTIDDVI
CVIDSCRARI SISQDNLSFK FVSEWASKVN LNQRLGRAGR LRPGYCFRLC TKARYEELPP
DIEPQVFRVP LYNIVLSIKR LKLGNIREVL YSAVQPPPLR AIEDAERLLI ELECLDNRKR
LTPLGNTLAR LPLDPRLGRM LLMSIIFDCP FQILKLAAYA STQEELLDNT TEEMEKIGNE
RYSDHIAVLH ALSAGESLSH FQKLYETSAL NLLDEVNRIE EQLYKILYRM GFDLTSSSGT
EKETLDIITG LLCQAFYPNV CAITEKKSLK AKKVFLPSGK FGIHTQLSLI VDHNYKKEFK
PPSPIFVFGE QTETTVNVCR NLTMVSPMHL LCFTNCKVVY EKGVVKIDDW LQLEMDPNAA
AAVMCVRTMI EKALHEIVSD PSGVEMSNYN GLSAVVKQLC KTDFGQRTVD ASSICSSSER
LENESNS
//
