ID A2X9D0_ORYSI Unreviewed; 1067 AA.
AC A2X9D0;
DT 20-MAR-2007, integrated into UniProtKB/TrEMBL.
DT 20-MAR-2007, sequence version 1.
DT 27-MAR-2024, entry version 83.
DE RecName: Full=RNA-dependent RNA polymerase {ECO:0000256|RuleBase:RU363098};
DE EC=2.7.7.48 {ECO:0000256|RuleBase:RU363098};
GN ORFNames=OsI_08849 {ECO:0000313|EMBL:EAY87440.1};
OS Oryza sativa subsp. indica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39946 {ECO:0000313|EMBL:EAY87440.1, ECO:0000313|Proteomes:UP000007015};
RN [1] {ECO:0000313|EMBL:EAY87440.1, ECO:0000313|Proteomes:UP000007015}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. 93-11 {ECO:0000313|Proteomes:UP000007015};
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C., Chen H., Xu Z., Li H., Huang H., Zhang F., Xu H.,
RA Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q., Li W.,
RA Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J., Gao L.,
RA Zheng W., Hao B., Liu S., Wang W., Yuan L., Cao M., McDermott J.,
RA Samudrala R., Wang J., Wong G.K., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
CC -!- FUNCTION: Probably involved in the RNA silencing pathway and required
CC for the generation of small interfering RNAs (siRNAs).
CC {ECO:0000256|RuleBase:RU363098}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC EC=2.7.7.48; Evidence={ECO:0000256|ARBA:ARBA00024517,
CC ECO:0000256|RuleBase:RU363098};
CC -!- SIMILARITY: Belongs to the RdRP family. {ECO:0000256|ARBA:ARBA00005762,
CC ECO:0000256|RuleBase:RU363098}.
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DR EMBL; CM000127; EAY87440.1; -; Genomic_DNA.
DR AlphaFoldDB; A2X9D0; -.
DR STRING; 39946.A2X9D0; -.
DR EnsemblPlants; BGIOSGA009008-TA; BGIOSGA009008-PA; BGIOSGA009008.
DR Gramene; BGIOSGA009008-TA; BGIOSGA009008-PA; BGIOSGA009008.
DR HOGENOM; CLU_001366_3_0_1; -.
DR OMA; CYNEGYE; -.
DR Proteomes; UP000007015; Chromosome 2.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003968; F:RNA-dependent RNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0031047; P:regulatory ncRNA-mediated gene silencing; IEA:UniProtKB-KW.
DR CDD; cd00590; RRM_SF; 1.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR007855; RNA-dep_RNA_pol_euk-typ.
DR InterPro; IPR000504; RRM_dom.
DR PANTHER; PTHR23079; RNA-DEPENDENT RNA POLYMERASE; 1.
DR PANTHER; PTHR23079:SF55; RNA-DIRECTED RNA POLYMERASE; 1.
DR Pfam; PF05183; RdRP; 2.
DR SMART; SM00360; RRM; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
PE 3: Inferred from homology;
KW Nucleotidyltransferase {ECO:0000256|RuleBase:RU363098};
KW Reference proteome {ECO:0000313|Proteomes:UP000007015};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|RuleBase:RU363098};
KW RNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022484,
KW ECO:0000256|RuleBase:RU363098};
KW RNA-mediated gene silencing {ECO:0000256|RuleBase:RU363098};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU363098}.
FT DOMAIN 5..84
FT /note="RRM"
FT /evidence="ECO:0000259|SMART:SM00360"
SQ SEQUENCE 1067 AA; 122479 MW; 1AD9EE336A57C6F7 CRC64;
MGVKTLQVSG FALDDSADYV KDLLERIVGC GNVYAVKLRH PKNVTATSRA YAIVQFQTEE
HASLVKNAAQ RKILRRGHYY LKVHPSDRDI VPRPRVSMFK LEDVTLHFGC LLKETILSAL
WSRTGVSVEF GFNLKKIYFY LQLPNSSIEY KLELSYESIW EIQLQRPPKS QTKFLLIQVQ
AAPKIYEQTP RRSGVMYEDP LFNYFRDHTD DQWTRTTDFT SSSSIGQSYI LCLEVPRRCD
LPNIRDYFFY YHEYNHDFEC RSGGYPYSSD TRFVPIVKSR GYVPYEILFK INHLVQNGTL
SGPTVDDSFF RLVSPAFVPI DHIKRALEMM SYLKKTCLNP TSWLSEQYSK FRRSRYVQPS
PNISLDDGLV YVYRVQVTPA KVYFYGPEIN VSNRVVRNFS SDIENFLRIS FVDEDCEKLR
ATDLSPRSAS GHDANRTALY KRVLLVLSDG ITIGGKNFEF LAFSSSQLRD NSAWMFASRQ
GLAASDIRTW MGDFRNIRNV AKYAARLGQS FSSSTETLKV QKYEVEEISD IKNGTQHVFS
DGIGKISSAF ANEVAMKCNL KRFAPSAFQI RYGGYKGVVA VDPTSRWKLS LRKSMLKFQS
DNITVDVLAY SKYQPGFLNR QLITLLSTLG VRDSVFEQKQ EEAVNQLNKM VTDPQAAIEA
IELMPMGEIT NAVKELLLCG YQPDDEPYLS MLLQTFRASK LLELKTKSRI LIPKGRAMMG
CLDETRTLKY GQVFIRATSG VNDNDRPHPN ECSGSDLDGD IYFVSWDPSL IPPRMVTPMD
YTPAPTETLD HDVTIEEVEE YFTNYIVNES LGMIANAHVV FADKEDLKAE SSPCIELAKL
FSIAVDFPKT GVPALIPPEL HVKEYPDFME KLDKVTYESK GVIGKLYREI KKHTPHIKHF
TREVARRSYD TDMIVDGYED YITEAMALKD EYDFKLGNLM DHYGIKSEAE IISGCILKMA
KNFTKKSDAD AIRLAVRSLR KEARSRFSEM SLDDNGHGHD ASEAKASAWY HVTYHPEFWG
CYNEGYERPH FISFPWCIYE KLLRIKQRRK FVRKMQPELF SLHNLRI
//
