ID   B9S355_RICCO            Unreviewed;      1058 AA.
AC   B9S355;
DT   24-MAR-2009, integrated into UniProtKB/TrEMBL.
DT   24-MAR-2009, sequence version 1.
DT   27-MAR-2024, entry version 67.
DE   RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE            EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
GN   ORFNames=RCOM_1398510 {ECO:0000313|EMBL:EEF41979.1};
OS   Ricinus communis (Castor bean).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; fabids; Malpighiales; Euphorbiaceae; Acalyphoideae; Acalypheae;
OC   Ricinus.
OX   NCBI_TaxID=3988 {ECO:0000313|Proteomes:UP000008311};
RN   [1] {ECO:0000313|Proteomes:UP000008311}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Hale {ECO:0000313|Proteomes:UP000008311};
RX   PubMed=20729833; DOI=10.1038/nbt.1674;
RA   Chan A.P., Crabtree J., Zhao Q., Lorenzi H., Orvis J., Puiu D.,
RA   Melake-Berhan A., Jones K.M., Redman J., Chen G., Cahoon E.B., Gedil M.,
RA   Stanke M., Haas B.J., Wortman J.R., Fraser-Liggett C.M., Ravel J.,
RA   Rabinowicz P.D.;
RT   "Draft genome sequence of the oilseed species Ricinus communis.";
RL   Nat. Biotechnol. 28:951-956(2010).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC         Evidence={ECO:0000256|ARBA:ARBA00001556};
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DR   EMBL; EQ973856; EEF41979.1; -; Genomic_DNA.
DR   AlphaFoldDB; B9S355; -.
DR   STRING; 3988.B9S355; -.
DR   eggNOG; KOG0920; Eukaryota.
DR   InParanoid; B9S355; -.
DR   Proteomes; UP000008311; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004386; F:helicase activity; IBA:GO_Central.
DR   GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR   GO; GO:0003724; F:RNA helicase activity; IEA:UniProtKB-EC.
DR   CDD; cd17917; DEXHc_RHA-like; 1.
DR   CDD; cd00048; DSRM_SF; 1.
DR   CDD; cd18791; SF2_C_RHA; 1.
DR   Gene3D; 1.20.120.1080; -; 1.
DR   Gene3D; 3.30.160.20; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR014720; dsRBD_dom.
DR   InterPro; IPR048333; HA2_WH.
DR   InterPro; IPR007502; Helicase-assoc_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR   PANTHER; PTHR18934:SF229; ATP-DEPENDENT RNA HELICASE DHX30; 1.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF00035; dsrm; 1.
DR   Pfam; PF21010; HA2_C; 1.
DR   Pfam; PF04408; HA2_N; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   Pfam; PF07717; OB_NTP_bind; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00847; HA2; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF54768; dsRNA-binding domain-like; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Helicase {ECO:0000313|EMBL:EEF41979.1};
KW   Hydrolase {ECO:0000313|EMBL:EEF41979.1};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008311}.
FT   DOMAIN          209..376
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          465..639
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
SQ   SEQUENCE   1058 AA;  119075 MW;  069F77C8E948C6A3 CRC64;
     MMNHQTLSFK HHQGVVRFAY QGVTSDDSDL EVGSYSQQAM SGSTLDNIED WRWKFTMLLR
     NKDGQEIVSR EKNRQYSRVV VFSKIPQPNY RPDLDDKRPQ REVTLPFGLQ REVDAHLNAY
     LSKKSTNREN FSVNFLPKSS NGKSMANTEG VYEQPDPMIK NNVVMERILR RKSLQLQTKQ
     QEWQETPEGQ KMAEFRQSLP AYKERDALLK AISENQVVVV SGETGCGKTT QLPQYILESE
     IEAARGGACS IICTQPRRIS AMAVSERVAA ERGEKLGESV GYKVRLEGIK GRDTRLLFCT
     TGILLRRLLV DRNLNGVTHV IVDEIHERGM NEDFLLIVLR DLLPHRPELR LILMSATLNA
     ELFSSYFGGA PTLHIPGFTY PVRAHFLEDI LELTGHRLTP YNQIDDYGQE KGWKMQKQAQ
     AFRKRKTQIA SAVEDALEAA NFKGYSLRTQ ESLSSWNPDS IGFNLIERVL CHIVKKERPG
     AVLVFMTGWD DISSLKDQLQ THPVLGDPSR ILLLACHGSM DSSEQRLIFD KPKDGVHKIV
     LATNMAETSI TIPDAVFVVD CGKAKETSYD ALNNTPCLLP SWISKAAARQ RRGRAGRVQP
     GECYHLYPRC VYDAFADYQL PELLRTPLQS LCLQIKSLQL GSISEFLSRA LQPPEPLSVQ
     NAIEYLKVIG ALDENENLTL LGRHLSMLPV EPKLGKMLIL GAIFNCLDPV MTVVSGLSVR
     DPFLMPFDKK DLAESAKAQF SARDYSDHLA LVRAFDGWKD AERQQSGYEY CWKNFLSAQT
     MRAIDALRKQ FFYLLKDTGL LGQKTEDCSM LSHDEHLIRA IICAGLFPGI CSVVNKEKSI
     TLKTMEDGQV LLHSNSVNAG IPKIPYPWLV FNEKVKVNSV FLRDSSGVSD SVLLLFGGDL
     SRGGLDGHLK MLGGYLEFFM KPALADTYLS LKRELEELIQ KKLLDPKLDI QSHNELLMAI
     RLLVSEDQCE GHGPPTYKTK QLKNNQFRST VIFNGLNFVG QPCNTKKLAE KDAAAEALLW
     LKGEVHSSSR DINHASALLK KSNKKTKNKA LLHGGKWS
//