ID D7BQF6_STRBB Unreviewed; 587 AA.
AC D7BQF6;
DT 10-AUG-2010, integrated into UniProtKB/TrEMBL.
DT 10-AUG-2010, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
GN OrderedLocusNames=SBI_04064 {ECO:0000313|EMBL:ADI07185.1};
OS Streptomyces bingchenggensis (strain BCW-1).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=749414 {ECO:0000313|EMBL:ADI07185.1, ECO:0000313|Proteomes:UP000000377};
RN [1] {ECO:0000313|EMBL:ADI07185.1, ECO:0000313|Proteomes:UP000000377}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BCW-1 {ECO:0000313|EMBL:ADI07185.1,
RC ECO:0000313|Proteomes:UP000000377};
RX PubMed=20581206; DOI=10.1128/JB.00596-10;
RA Wang X.J., Yan Y.J., Zhang B., An J., Wang J.J., Tian J., Jiang L.,
RA Chen Y.H., Huang S.X., Yin M., Zhang J., Gao A.L., Liu C.X., Zhu Z.X.,
RA Xiang W.S.;
RT "Genome sequence of the milbemycin-producing bacterium Streptomyces
RT bingchenggensis.";
RL J. Bacteriol. 192:4526-4527(2010).
CC -!- SIMILARITY: Belongs to the DEAD box helicase family.
CC {ECO:0000256|RuleBase:RU000492}.
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DR EMBL; CP002047; ADI07185.1; -; Genomic_DNA.
DR AlphaFoldDB; D7BQF6; -.
DR STRING; 749414.SBI_04064; -.
DR KEGG; sbh:SBI_04064; -.
DR PATRIC; fig|749414.3.peg.4204; -.
DR eggNOG; COG0513; Bacteria.
DR HOGENOM; CLU_003041_27_2_11; -.
DR Proteomes; UP000000377; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:UniProt.
DR CDD; cd00268; DEADc; 1.
DR CDD; cd18787; SF2_C_DEAD; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000629; RNA-helicase_DEAD-box_CS.
DR PANTHER; PTHR47963:SF8; ATP-DEPENDENT RNA HELICASE DEAD; 1.
DR PANTHER; PTHR47963; DEAD-BOX ATP-DEPENDENT RNA HELICASE 47, MITOCHONDRIAL; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00039; DEAD_ATP_HELICASE; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU000492};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|RuleBase:RU000492};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU000492};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU000492};
KW Reference proteome {ECO:0000313|Proteomes:UP000000377}.
FT DOMAIN 1..182
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 211..359
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 379..587
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 379..395
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 494..509
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 587 AA; 62189 MW; A8817F799EE1DC2E CRC64;
MALSGSDVIG QAKTGTGKTL GFGLPLLERV TVPADVEAGR AKPELLTDAP QALVVVPTRE
LCQQVTNDLL TAGKVRAVRV LSIYGGRAYE PQVEALKKGV DVVVGTPGRL LDLAGQKKLR
LSSVKSLVLD EADEMLDLGF LPDVEKIIQM LPAKRQTMLF SATMPGQVIS LARRYMSQPT
HIRATAPDDE GATVANITQH VFRAHSLDKP EVVARVLQAE GRGLVMIFCR TKRTAADIAD
QLAHRGFASG AVHGDLGQGA REQALRAFRN GKVDVLVATD VAARGIDVEG VTHVINYQSP
EDEKTYLHRI GRTGRAGASG TAITLVDWDD IPRWQLINKA LDLPFSEPEE TYSTSDHLYE
LLNIPEGTTG VLPRAERTRA GLDAEEIEDL GETGARGARS ARGSRRSSAA PAEERPARTR
TPRQRRRLRG GVVVDGVTGD STQAAETAVD TAEGTAEAPA AEATAEPRQP RRRRRTRAGV
TAKAADSGTD AEAAVTTAEG STTAVADTAQ PQPEAAPDAA EAPAKPRRRR TRGAATAKAA
DATAAPAPAP APQAEAAPAE AGEGEAKPVR RRRRTRSAAS KTEATEG
//
