ID E4T5H3_PALPW Unreviewed; 482 AA.
AC E4T5H3;
DT 08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT 08-FEB-2011, sequence version 1.
DT 27-MAR-2024, entry version 67.
DE SubName: Full=Tryptophanase {ECO:0000313|EMBL:ADQ79967.1};
DE EC=4.1.99.1 {ECO:0000313|EMBL:ADQ79967.1};
GN OrderedLocusNames=Palpr_1828 {ECO:0000313|EMBL:ADQ79967.1};
OS Paludibacter propionicigenes (strain DSM 17365 / JCM 13257 / WB4).
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Paludibacteraceae;
OC Paludibacter.
OX NCBI_TaxID=694427 {ECO:0000313|EMBL:ADQ79967.1, ECO:0000313|Proteomes:UP000008718};
RN [1]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=WB4;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Copeland A., Lapidus A., Bruce D., Goodwin L., Pitluck S.,
RA Kyrpides N., Mavromatis K., Ivanova N., Munk A.C., Brettin T., Detter J.C.,
RA Han C., Tapia R., Land M., Hauser L., Markowitz V., Cheng J.-F.,
RA Hugenholtz P., Woyke T., Wu D., Gronow S., Wellnitz S., Brambilla E.,
RA Klenk H.-P., Eisen J.A.;
RT "The complete genome of Paludibacter propionicigenes DSM 17365.";
RL Submitted (NOV-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ADQ79967.1, ECO:0000313|Proteomes:UP000008718}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17365 / JCM 13257 / WB4
RC {ECO:0000313|Proteomes:UP000008718};
RX PubMed=21475585; DOI=10.4056/sigs.1503846;
RA Gronow S., Munk C., Lapidus A., Nolan M., Lucas S., Hammon N.,
RA Deshpande S., Cheng J.F., Tapia R., Han C., Goodwin L., Pitluck S.,
RA Liolios K., Ivanova N., Mavromatis K., Mikhailova N., Pati A., Chen A.,
RA Palaniappan K., Land M., Hauser L., Chang Y.J., Jeffries C.D.,
RA Brambilla E., Rohde M., Goker M., Detter J.C., Woyke T., Bristow J.,
RA Eisen J.A., Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.P.;
RT "Complete genome sequence of Paludibacter propionicigenes type strain
RT (WB4).";
RL Stand. Genomic Sci. 4:36-44(2011).
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933,
CC ECO:0000256|PIRSR:PIRSR611166-50};
CC -!- SIMILARITY: Belongs to the beta-eliminating lyase family.
CC {ECO:0000256|ARBA:ARBA00009721}.
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DR EMBL; CP002345; ADQ79967.1; -; Genomic_DNA.
DR RefSeq; WP_013445336.1; NC_014734.1.
DR AlphaFoldDB; E4T5H3; -.
DR STRING; 694427.Palpr_1828; -.
DR GeneID; 78491374; -.
DR KEGG; ppn:Palpr_1828; -.
DR eggNOG; COG3033; Bacteria.
DR HOGENOM; CLU_047223_0_0_10; -.
DR OrthoDB; 9764079at2; -.
DR Proteomes; UP000008718; Chromosome.
DR GO; GO:0009034; F:tryptophanase activity; IEA:UniProtKB-EC.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR001597; ArAA_b-elim_lyase/Thr_aldolase.
DR InterPro; IPR011166; Beta-eliminating_lyase.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR PANTHER; PTHR32325; BETA-ELIMINATING LYASE-LIKE PROTEIN-RELATED; 1.
DR PANTHER; PTHR32325:SF4; TRYPTOPHANASE; 1.
DR Pfam; PF01212; Beta_elim_lyase; 1.
DR PIRSF; PIRSF001386; Trpase; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000313|EMBL:ADQ79967.1};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW ECO:0000256|PIRSR:PIRSR611166-50};
KW Reference proteome {ECO:0000313|Proteomes:UP000008718}.
FT DOMAIN 55..428
FT /note="Aromatic amino acid beta-eliminating lyase/threonine
FT aldolase"
FT /evidence="ECO:0000259|Pfam:PF01212"
FT MOD_RES 266
FT /note="N6-(pyridoxal phosphate)lysine"
FT /evidence="ECO:0000256|PIRSR:PIRSR611166-50"
SQ SEQUENCE 482 AA; 54088 MW; 9EA0E9FC0FC012E7 CRC64;
MQEIKFYSGE NIPLELHKVR IVQKLHLVPI ERRLEALYEG GFNTFRLSTK DVFLDMLTDS
GTNAMSDNQL AAMMQGDDAY AGSQSFYRLE KAVQDVLGKK YLLPVHQGRA AENIIALAYV
KKGSLVPMNY HFTTAMAHIT DKGGQIVELL YDEAYVVNSD HPFKGNMNIE KLEEVIKRHS
AANIPFIRME ASTNLIGGQP FSVQNLRDVR AIADKYGIRI VLDCSLLGEN AYLVLKREEE
FKNSDMATVL KTMTGLADLC YFSARKISSS RGGGMCTDRL EIMKELEALV PLYEGFLTYG
GISVREIEAM AVGLYETLDE TMICQSPNFI KYLVDSLYAK GVPMIKPAGV LGAHVDAMQV
CAHIPQTEYP AGALAAALFL ISGIRGMERG SISNQRDEEG NETYADMELL RLAVPRRVFT
LSQIKYVEDR MHWLYDNREL IGGLRFVYEP PVLRFFMGGL EPTSDWPQKL MAKFKADFGE
SL
//
