ID E9GZN9_DAPPU Unreviewed; 875 AA.
AC E9GZN9;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
GN ORFNames=DAPPUDRAFT_306924 {ECO:0000313|EMBL:EFX75071.1};
OS Daphnia pulex (Water flea).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Branchiopoda;
OC Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia.
OX NCBI_TaxID=6669 {ECO:0000313|EMBL:EFX75071.1, ECO:0000313|Proteomes:UP000000305};
RN [1] {ECO:0000313|EMBL:EFX75071.1, ECO:0000313|Proteomes:UP000000305}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21292972; DOI=10.1126/science.1197761;
RA Colbourne J.K., Pfrender M.E., Gilbert D., Thomas W.K., Tucker A.,
RA Oakley T.H., Tokishita S., Aerts A., Arnold G.J., Basu M.K., Bauer D.J.,
RA Caceres C.E., Carmel L., Casola C., Choi J.H., Detter J.C., Dong Q.,
RA Dusheyko S., Eads B.D., Frohlich T., Geiler-Samerotte K.A., Gerlach D.,
RA Hatcher P., Jogdeo S., Krijgsveld J., Kriventseva E.V., Kultz D.,
RA Laforsch C., Lindquist E., Lopez J., Manak J.R., Muller J., Pangilinan J.,
RA Patwardhan R.P., Pitluck S., Pritham E.J., Rechtsteiner A., Rho M.,
RA Rogozin I.B., Sakarya O., Salamov A., Schaack S., Shapiro H., Shiga Y.,
RA Skalitzky C., Smith Z., Souvorov A., Sung W., Tang Z., Tsuchiya D., Tu H.,
RA Vos H., Wang M., Wolf Y.I., Yamagata H., Yamada T., Ye Y., Shaw J.R.,
RA Andrews J., Crease T.J., Tang H., Lucas S.M., Robertson H.M., Bork P.,
RA Koonin E.V., Zdobnov E.M., Grigoriev I.V., Lynch M., Boore J.L.;
RT "The ecoresponsive genome of Daphnia pulex.";
RL Science 331:555-561(2011).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC Evidence={ECO:0000256|ARBA:ARBA00001556};
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DR EMBL; GL732578; EFX75071.1; -; Genomic_DNA.
DR AlphaFoldDB; E9GZN9; -.
DR STRING; 6669.E9GZN9; -.
DR EnsemblMetazoa; EFX75071; EFX75071; DAPPUDRAFT_306924.
DR KEGG; dpx:DAPPUDRAFT_306924; -.
DR eggNOG; KOG0334; Eukaryota.
DR eggNOG; KOG2279; Eukaryota.
DR HOGENOM; CLU_328535_0_0_1; -.
DR InParanoid; E9GZN9; -.
DR OMA; NAEMTEY; -.
DR PhylomeDB; E9GZN9; -.
DR Proteomes; UP000000305; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0042078; P:germ-line stem cell division; IBA:GO_Central.
DR CDD; cd20435; Tudor_TDRD12_rpt2; 1.
DR Gene3D; 2.30.30.140; -; 2.
DR Gene3D; 2.40.50.90; -; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR035437; SNase_OB-fold_sf.
DR InterPro; IPR002999; Tudor.
DR PANTHER; PTHR22655:SF2; ATP-DEPENDENT RNA HELICASE TDRD12-RELATED; 1.
DR PANTHER; PTHR22655; UNCHARACTERIZED; 1.
DR Pfam; PF00567; TUDOR; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 2.
DR PROSITE; PS50304; TUDOR; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000000305};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 698..761
FT /note="Tudor"
FT /evidence="ECO:0000259|PROSITE:PS50304"
SQ SEQUENCE 875 AA; 99335 MW; 1FE132EFEC3BE989 CRC64;
MDLSEYSDVP IGCSPLVVVI CSSWENAELV QFYCSRIMKK NSDFRSAVFT DATERSLKVA
LPYLINGVTL LAATAPALNL LLTKAKDIIS FDRCCHLVFD DADVVLKEHG ESTKKLFNFY
QESVQRATMG NNFIPRQIVA CANHWTKGME EMSSKVLKNP SIFISSCMES AIYGGMKLDV
RRGTPEEMDR DLLEIVQSKR FSRTIIFCRG SAEVFKVEQM LSEIGATPIL AHNPIVSDLD
FTTERWNHAQ PGSAILICTD DVLERLNIKN AQTLIHYFIP HHSKYDFSYR LSFAMDNFHL
RASEADRPET HLLITKEFNN SLLTIVRLMQ RFGHVVPDEL ATEAILSFCG KEVRKRSLPL
CETLKAFGFC RNMKLCGLRH VILSTLDHPV VPQNGIVRIR ITAVRTATQY YARILKHRNE
KNQVIDMSGS HFEVSAQLRN HFRDEAQRKN SVDGNKVEAG NIYAHRTTDN LYERVRVESI
LERDHQGIPI EVTVISIDQG CVMSSFVKDL YEIPDDLKNS APEAIEVFLV GAKPFDRNSN
WSRYSVDFVR EKLMSKELEG RIVLALSFTL WLDPLHERKR LDGVNSSVVV TDILKDLLTA
ELADNNEEHL VKLYHLCETG GIELPNYSFG LAKNKSANPI EPSYAFLPMN EETQVELVTT
DSPHQFYVTI NKFQDTLRSL EADIKKQISK CKHVTYEDAQ LGSFCLVESP SEPGSWCRCC
IKKKIVEDDV WKFQVLFVDY GDHTKVPLNA MKSLPNQFIS RLPFQAIACS LYGVGPKNDS
GGWTEEDICF FTSLTRASDG FMHVWHAQTK FKEAVKDEVT NGSHYHVTLL NREEKEIPSL
AQQMISKNYA ISLENEEDFR AIAKVTLPEA LRGMG
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