ID   F4LWD4_TEPAE            Unreviewed;       397 AA.
AC   F4LWD4; L0RZP8;
DT   28-JUN-2011, integrated into UniProtKB/TrEMBL.
DT   28-JUN-2011, sequence version 1.
DT   27-MAR-2024, entry version 66.
DE   SubName: Full=Dimethylglycine dehydrogenase {ECO:0000313|EMBL:CCP26500.1};
DE            EC=1.5.8.4 {ECO:0000313|EMBL:CCP26500.1};
GN   OrderedLocusNames=TEPIRE1_1714 {ECO:0000313|EMBL:CCP26500.1};
OS   Tepidanaerobacter acetatoxydans (strain DSM 21804 / JCM 16047 / Re1).
OC   Bacteria; Bacillota; Clostridia; Thermosediminibacterales;
OC   Tepidanaerobacteraceae; Tepidanaerobacter.
OX   NCBI_TaxID=1209989 {ECO:0000313|EMBL:CCP26500.1, ECO:0000313|Proteomes:UP000010802};
RN   [1] {ECO:0000313|Proteomes:UP000010802}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Re1 {ECO:0000313|Proteomes:UP000010802};
RX   PubMed=23469343; DOI=10.1128/genomeA.00213-12;
RA   Manzoor S., Bongcam-Rudloff E., Schnurer A., Muller B.;
RT   "First genome sequence of a syntrophic acetate-oxidizing bacterium,
RT   Tepidanaerobacter acetatoxydans strain Re1.";
RL   Genome Announc. 1:E00213-E00213(2013).
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DR   EMBL; HF563609; CCP26500.1; -; Genomic_DNA.
DR   RefSeq; WP_013778655.1; NC_019954.2.
DR   AlphaFoldDB; F4LWD4; -.
DR   STRING; 1209989.TepRe1_1592; -.
DR   KEGG; tae:TepiRe1_1714; -.
DR   KEGG; tep:TepRe1_1592; -.
DR   PATRIC; fig|1209989.3.peg.1971; -.
DR   eggNOG; COG0665; Bacteria.
DR   HOGENOM; CLU_007884_4_3_9; -.
DR   OrthoDB; 9794226at2; -.
DR   Proteomes; UP000010802; Chromosome.
DR   GO; GO:0047865; F:dimethylglycine dehydrogenase activity; IEA:UniProtKB-EC.
DR   Gene3D; 3.30.9.10; D-Amino Acid Oxidase, subunit A, domain 2; 1.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR   InterPro; IPR006076; FAD-dep_OxRdtase.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   PANTHER; PTHR13847; SARCOSINE DEHYDROGENASE-RELATED; 1.
DR   PANTHER; PTHR13847:SF293; TRNA 5-METHYLAMINOMETHYL-2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC; 1.
DR   Pfam; PF01266; DAO; 1.
DR   SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000313|EMBL:CCP26500.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000010802}.
FT   DOMAIN          6..369
FT                   /note="FAD dependent oxidoreductase"
FT                   /evidence="ECO:0000259|Pfam:PF01266"
SQ   SEQUENCE   397 AA;  42794 MW;  00837CBB6EBB1E38 CRC64;
     MKKNADAVVA GGGVIGTSIA YYLSKKGMEI ILLEKDDLAS GSSGACDIDI ILQSKNPGIH
     LQLAMESAKM YKTLADELDF DIEYKATGGM ILIENEDQLK VMKDFVRRQK EIGLEVKLLS
     LKEASKIQPG LSPHLVGATY SLLDAHVNPM RLCFAFSRAA KRLGAKVYLG TSVLDIRAEN
     SKVKSVITNR GEIKTNIIIN AAGVYAPFIG EMVGLSLPIK PRRGQIIVTE SVPKLVMADV
     LCAKYIAAKY NPNILKESDN PETRLGVGLS LSQTRDGQIL IGSTREFVGY NKNTTHEALH
     AIVNNAVRLV PALRNIHAIR SFAGLRPYTP DGLPLLGPVE NVQGFIMAAG HEGDGIALSP
     VTGKIISDLI TEGKTFMDVS ELSPSRFGPL LGNENAV
//