ID F9XQ35_ZYMTI Unreviewed; 959 AA.
AC F9XQ35;
DT 19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT 19-OCT-2011, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE RecName: Full=RNA-dependent RNA polymerase {ECO:0000256|RuleBase:RU363098};
DE EC=2.7.7.48 {ECO:0000256|RuleBase:RU363098};
DE Flags: Fragment;
GN Name=RDR2402 {ECO:0000313|EMBL:EGP82572.1};
GN ORFNames=MYCGRDRAFT_51407 {ECO:0000313|EMBL:EGP82572.1};
OS Zymoseptoria tritici (strain CBS 115943 / IPO323) (Speckled leaf blotch
OS fungus) (Septoria tritici).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetidae; Mycosphaerellales; Mycosphaerellaceae; Zymoseptoria.
OX NCBI_TaxID=336722 {ECO:0000313|EMBL:EGP82572.1, ECO:0000313|Proteomes:UP000008062};
RN [1] {ECO:0000313|EMBL:EGP82572.1, ECO:0000313|Proteomes:UP000008062}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 115943 / IPO323 {ECO:0000313|Proteomes:UP000008062};
RX PubMed=21695235; DOI=10.1371/journal.pgen.1002070;
RA Goodwin S.B., Ben M'barek S., Dhillon B., Wittenberg A.H.J., Crane C.F.,
RA Hane J.K., Foster A.J., Van der Lee T.A.J., Grimwood J., Aerts A.,
RA Antoniw J., Bailey A., Bluhm B., Bowler J., Bristow J., van der Burgt A.,
RA Canto-Canche B., Churchill A.C.L., Conde-Ferraez L., Cools H.J.,
RA Coutinho P.M., Csukai M., Dehal P., De Wit P., Donzelli B.,
RA van de Geest H.C., van Ham R.C.H.J., Hammond-Kosack K.E., Henrissat B.,
RA Kilian A., Kobayashi A.K., Koopmann E., Kourmpetis Y., Kuzniar A.,
RA Lindquist E., Lombard V., Maliepaard C., Martins N., Mehrabi R.,
RA Nap J.P.H., Ponomarenko A., Rudd J.J., Salamov A., Schmutz J.,
RA Schouten H.J., Shapiro H., Stergiopoulos I., Torriani S.F.F., Tu H.,
RA de Vries R.P., Waalwijk C., Ware S.B., Wiebenga A., Zwiers L.-H.,
RA Oliver R.P., Grigoriev I.V., Kema G.H.J.;
RT "Finished genome of the fungal wheat pathogen Mycosphaerella graminicola
RT reveals dispensome structure, chromosome plasticity, and stealth
RT pathogenesis.";
RL PLoS Genet. 7:E1002070-E1002070(2011).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC EC=2.7.7.48; Evidence={ECO:0000256|ARBA:ARBA00024517,
CC ECO:0000256|RuleBase:RU363098};
CC -!- SIMILARITY: Belongs to the RdRP family. {ECO:0000256|ARBA:ARBA00005762,
CC ECO:0000256|RuleBase:RU363098}.
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DR EMBL; CM001208; EGP82572.1; -; Genomic_DNA.
DR RefSeq; XP_003847596.1; XM_003847548.1.
DR AlphaFoldDB; F9XQ35; -.
DR STRING; 336722.F9XQ35; -.
DR EnsemblFungi; Mycgr3T51407; Mycgr3P51407; Mycgr3G51407.
DR GeneID; 13401012; -.
DR KEGG; ztr:MYCGRDRAFT_51407; -.
DR eggNOG; KOG0988; Eukaryota.
DR HOGENOM; CLU_001366_0_2_1; -.
DR InParanoid; F9XQ35; -.
DR OMA; DDYLVIW; -.
DR OrthoDB; 5477883at2759; -.
DR Proteomes; UP000008062; Chromosome 13.
DR GO; GO:0005737; C:cytoplasm; IEA:EnsemblFungi.
DR GO; GO:0031934; C:mating-type region heterochromatin; IEA:EnsemblFungi.
DR GO; GO:0031380; C:nuclear RNA-directed RNA polymerase complex; IEA:EnsemblFungi.
DR GO; GO:0005721; C:pericentric heterochromatin; IEA:EnsemblFungi.
DR GO; GO:0140720; C:subtelomeric heterochromatin; IEA:EnsemblFungi.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003968; F:RNA-dependent RNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0033562; P:co-transcriptional gene silencing by RNA interference machinery; IEA:EnsemblFungi.
DR GO; GO:0070317; P:negative regulation of G0 to G1 transition; IEA:EnsemblFungi.
DR GO; GO:0140727; P:siRNA-dependent pericentric heterochromatin formation; IEA:EnsemblFungi.
DR InterPro; IPR007855; RNA-dep_RNA_pol_euk-typ.
DR PANTHER; PTHR23079; RNA-DEPENDENT RNA POLYMERASE; 1.
DR PANTHER; PTHR23079:SF55; RNA-DIRECTED RNA POLYMERASE; 1.
DR Pfam; PF05183; RdRP; 1.
PE 3: Inferred from homology;
KW Nucleotidyltransferase {ECO:0000256|RuleBase:RU363098};
KW Reference proteome {ECO:0000313|Proteomes:UP000008062};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|RuleBase:RU363098};
KW RNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022484,
KW ECO:0000256|RuleBase:RU363098};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU363098}.
FT NON_TER 959
FT /evidence="ECO:0000313|EMBL:EGP82572.1"
SQ SEQUENCE 959 AA; 108445 MW; BC7A3F6F6C7A36BE CRC64;
MHLVHGSDGC TSLVITTDFP SITTRKTTNI RATHNVKQSE WKEEWSDFRQ TDVDQNPMRR
SSAIQIRKSG CIIDTGRWRT YKITFAGDVA SSEAFLDVLQ ALRDHNVVLE TQEDLTFNEV
PPESLWKWQE ALAPPKVAGE AVSSLFDMLQ SHLAFSVHYQ LEVCISVGAL HESNIDRAFL
QRLSTIETVR AVKMLEKIAD EGKRIYKPSD IFSLHNRVSV VEKKRPAYCT KIPAANITPT
TIYFATPVLE TSNRVVRNYK KYEDRFMRVK FTDEKHKGQL QSQDGQAMNE VFSRIKQAMT
HGIRVADRHY EFLAFGNAQF REHGAYFFAS TPDLNANMIR QWMGNFTQIK NVAKYISRLG
QCYTTTRAIP HSVNVERIPD VERNGYCFTD GVGKISPLLA RMVADHFRLD NCPSVYQFRM
AGCKGVLAVD PSLKGMTVQI RPSQEKFPAE FHGLEICKMS QFSAANLNVQ LILVMSSLGV
PDNVFVNKYR DMLADLALAM TDEEMALKLL QKNIDFNQMT IYLATIILDG FMATKDPFTI
SCLRLWRSWN LKYLKEKARV FVDQGAFVFG VTDETGTLQG QFDGFKTDEG DMAVPPTLPQ
IFLQIPDPNA KGGYTVIQGP CLFARNPSLH PGDIRMVEAV DVPALHHLKD CVVLPQTGDR
DLANMCSGGD LDGDDYLICW DADLFPPVSD TGPVTVDDMT SFFVNYIKNN KLGQIASHHR
FWADKEDDGV KNEKCLQLAN LHSLAVDYVK TGVPATLPVE LKVKARPHWA EARGQSYTSR
KVLGQLYDEV KLDNFQPAWE LPFDARILTA DTPTPELIAG ATEVKAEYDE TMRRIMKQYG
ITNEFEVFTT FVQSHHNDIN DYKFYEKIGE VSMNLRDQFK EICYTKAGTD SVQREWSKLK
PFLIAMYTVT ADQVTAVVAS SHETVERGGR QVPKMSLTFA TVPLMSFPWI FASELGRIA
//
