GenomeNet

Database: UniProt
Entry: Q4P9P3
LinkDB: Q4P9P3
Original site: Q4P9P3 
ID   DRS1_USTMA              Reviewed;         932 AA.
AC   Q4P9P3; A0A0D1DWP5;
DT   04-APR-2006, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2005, sequence version 1.
DT   16-OCT-2019, entry version 87.
DE   RecName: Full=ATP-dependent RNA helicase DRS1;
DE            EC=3.6.4.13;
GN   Name=DRS1; ORFNames=UMAG_03170;
OS   Ustilago maydis (strain 521 / FGSC 9021) (Corn smut fungus).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC   Ustilaginomycetes; Ustilaginales; Ustilaginaceae; Ustilago.
OX   NCBI_TaxID=237631;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=521 / FGSC 9021;
RX   PubMed=17080091; DOI=10.1038/nature05248;
RA   Kaemper J., Kahmann R., Boelker M., Ma L.-J., Brefort T.,
RA   Saville B.J., Banuett F., Kronstad J.W., Gold S.E., Mueller O.,
RA   Perlin M.H., Woesten H.A.B., de Vries R., Ruiz-Herrera J.,
RA   Reynaga-Pena C.G., Snetselaar K., McCann M., Perez-Martin J.,
RA   Feldbruegge M., Basse C.W., Steinberg G., Ibeas J.I., Holloman W.,
RA   Guzman P., Farman M.L., Stajich J.E., Sentandreu R.,
RA   Gonzalez-Prieto J.M., Kennell J.C., Molina L., Schirawski J.,
RA   Mendoza-Mendoza A., Greilinger D., Muench K., Roessel N., Scherer M.,
RA   Vranes M., Ladendorf O., Vincon V., Fuchs U., Sandrock B., Meng S.,
RA   Ho E.C.H., Cahill M.J., Boyce K.J., Klose J., Klosterman S.J.,
RA   Deelstra H.J., Ortiz-Castellanos L., Li W., Sanchez-Alonso P.,
RA   Schreier P.H., Haeuser-Hahn I., Vaupel M., Koopmann E., Friedrich G.,
RA   Voss H., Schlueter T., Margolis J., Platt D., Swimmer C., Gnirke A.,
RA   Chen F., Vysotskaia V., Mannhaupt G., Gueldener U.,
RA   Muensterkoetter M., Haase D., Oesterheld M., Mewes H.-W.,
RA   Mauceli E.W., DeCaprio D., Wade C.M., Butler J., Young S.K.,
RA   Jaffe D.B., Calvo S.E., Nusbaum C., Galagan J.E., Birren B.W.;
RT   "Insights from the genome of the biotrophic fungal plant pathogen
RT   Ustilago maydis.";
RL   Nature 444:97-101(2006).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=521 / FGSC 9021;
RA   Gueldener U., Muensterkoetter M., Walter M.C., Mannhaupt G.,
RA   Kahmann R.;
RL   Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: ATP-binding RNA helicase involved in ribosome assembly.
CC       {ECO:0000250}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC   -!- SUBUNIT: Associates with pre-ribosomal particles. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- DOMAIN: The Q motif is unique to and characteristic of the DEAD
CC       box family of RNA helicases and controls ATP binding and
CC       hydrolysis.
CC   -!- SIMILARITY: Belongs to the DEAD box helicase family. DDX27/DRS1
CC       subfamily. {ECO:0000305}.
DR   EMBL; CM003147; KIS68599.1; -; Genomic_DNA.
DR   RefSeq; XP_011389627.1; XM_011391325.1.
DR   SMR; Q4P9P3; -.
DR   STRING; 5270.UM03170P0; -.
DR   EnsemblFungi; KIS68599; KIS68599; UMAG_03170.
DR   GeneID; 23563715; -.
DR   KEGG; uma:UMAG_03170; -.
DR   EuPathDB; FungiDB:UMAG_03170; -.
DR   HOGENOM; HOG000265456; -.
DR   InParanoid; Q4P9P3; -.
DR   KO; K13181; -.
DR   OMA; TIERLTW; -.
DR   OrthoDB; 973872at2759; -.
DR   Proteomes; UP000000561; Chromosome 8.
DR   Proteomes; UP000000561; Unassembled WGS sequence.
DR   GO; GO:0005730; C:nucleolus; IBA:GO_Central.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR   GO; GO:0003724; F:RNA helicase activity; IEA:UniProtKB-EC.
DR   GO; GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR000629; RNA-helicase_DEAD-box_CS.
DR   InterPro; IPR014014; RNA_helicase_DEAD_Q_motif.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS00039; DEAD_ATP_HELICASE; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
DR   PROSITE; PS51195; Q_MOTIF; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Helicase; Hydrolase;
KW   Nucleotide-binding; Nucleus; Reference proteome; Ribosome biogenesis;
KW   RNA-binding.
FT   CHAIN         1    932       ATP-dependent RNA helicase DRS1.
FT                                /FTId=PRO_0000232248.
FT   DOMAIN      364    543       Helicase ATP-binding.
FT                                {ECO:0000255|PROSITE-ProRule:PRU00541}.
FT   DOMAIN      601    748       Helicase C-terminal.
FT                                {ECO:0000255|PROSITE-ProRule:PRU00542}.
FT   NP_BIND     377    384       ATP. {ECO:0000255|PROSITE-
FT                                ProRule:PRU00541}.
FT   MOTIF       333    361       Q motif.
FT   MOTIF       490    493       DEAD box.
FT   COMPBIAS    200    296       Asp-rich.
SQ   SEQUENCE   932 AA;  102119 MW;  D6210D9C2D5DCD98 CRC64;
     MRVQQSKPSA AAKRKAAATS LTTSPQKKRA NTTPKRAKDD DFIMTLDSDD DVEDLDAAHV
     DADHVASDNS EREPEPEAEL EPEHSSTPPD GKLTKNQRKR KEKAHLVGKE KIIESLASRS
     KTNSAAAVKD AMALDKDFEF DIFGDGSAVD YTGAEANGWD MSVTGTRMHK KLNVDDIIEK
     RRKVLPTLPA PVEEEEENSD EDDQDDDLDD DIKYAEYQDS DDDEDRFGGG NGNIVGQNKD
     EDQQDAAELD SQEDPLSSDA ESASDDDDDN DNDDDDDELQ VAEQDEESNS SEDDSDLETE
     QEKARKAAFF AEDPIATSAD SSSKSKSTND AESSFGAFDL SRPVLRALSS LSFHKPTPIQ
     SRTIPIALAG KDIVAGAVTG SGKTAAFMIP TIERLTWRAK TRTPHEAKSR VLILAPTREL
     AIQCYSVGKS IAKFTDIRFC LCVGGLSVKS QEAELKLRPE VVIATPGRLI DHVRNSASFT
     LDDIEILVMD EADRMLEDGF ADELNEIVKS CPKGARQTML FSATMTDDVE QLVRLSLKRP
     VRLFVDPKRT TAKKLIQEFV RVRGTGTGGV AGADGLSGIQ DQPATWISGG RKSEDAQRPA
     LLLSLCTRTF TSQTMIFVRS KKLAHQLKIV FGLLGLSAGE LHGDLSQEQR IDALTDFRDG
     KTDFLLATDL ASRGLDIKGV QTVINYDMPG QFEAYLHRVG RTARAGRNGR AVTLVGEADR
     RMLKLAIKKS SAEQIKHRII PSAVAAHMCE TLERLKPEVD AVLREEKEEK ALRIAEMELK
     KGENMANHAD EIFSRPKRTW FQSGSEKTQA SALSKAGYQA TMDARSSSKQ KDKYAGLSRK
     KRRSKMMRQE IERERKDASG SAGAKTASGG GMDAGIRAAK KAQRPTKLGV APLKLANKSK
     GKQSGRNARP SATGGSKTKS SFNRDFSGNK RR
//
DBGET integrated database retrieval system