ID R0IR48_9BRAS Unreviewed; 717 AA.
AC R0IR48;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
GN ORFNames=CARUB_v10008395mg {ECO:0000313|EMBL:EOA39748.1};
OS Capsella rubella.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Capsella.
OX NCBI_TaxID=81985 {ECO:0000313|EMBL:EOA39748.1, ECO:0000313|Proteomes:UP000029121};
RN [1] {ECO:0000313|Proteomes:UP000029121}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Monte Gargano {ECO:0000313|Proteomes:UP000029121};
RX PubMed=23749190; DOI=10.1038/ng.2669;
RA Slotte T., Hazzouri K.M., Agren J.A., Koenig D., Maumus F., Guo Y.L.,
RA Steige K., Platts A.E., Escobar J.S., Newman L.K., Wang W., Mandakova T.,
RA Vello E., Smith L.M., Henz S.R., Steffen J., Takuno S., Brandvain Y.,
RA Coop G., Andolfatto P., Hu T.T., Blanchette M., Clark R.M., Quesneville H.,
RA Nordborg M., Gaut B.S., Lysak M.A., Jenkins J., Grimwood J., Chapman J.,
RA Prochnik S., Shu S., Rokhsar D., Schmutz J., Weigel D., Wright S.I.;
RT "The Capsella rubella genome and the genomic consequences of rapid mating
RT system evolution.";
RL Nat. Genet. 45:831-835(2013).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC Evidence={ECO:0000256|ARBA:ARBA00001556};
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DR EMBL; KB870805; EOA39748.1; -; Genomic_DNA.
DR RefSeq; XP_006306850.1; XM_006306788.1.
DR AlphaFoldDB; R0IR48; -.
DR GeneID; 17900420; -.
DR KEGG; crb:17900420; -.
DR OrthoDB; 3682876at2759; -.
DR Proteomes; UP000029121; Unassembled WGS sequence.
DR GO; GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:UniProtKB-EC.
DR GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR CDD; cd17978; DEXHc_DHX33; 1.
DR CDD; cd18791; SF2_C_RHA; 1.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR PANTHER; PTHR18934:SF118; ATP-DEPENDENT RNA HELICASE DHX33; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF21010; HA2_C; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF07717; OB_NTP_bind; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00847; HA2; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW mRNA processing {ECO:0000256|ARBA:ARBA00022664};
KW mRNA splicing {ECO:0000256|ARBA:ARBA00023187};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000029121};
KW Spliceosome {ECO:0000256|ARBA:ARBA00022728}.
FT DOMAIN 51..256
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 281..453
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 717 AA; 81026 MW; 6E897D367BB3B233 CRC64;
MPSMAQREFR SSVQNSKPNP KFPTVSHFSM RQKIAEHRRS LPIATVEKRL IEEVRKNDIL
IVVGETGSGK TTQLPQFLYN AGFCREGKMV GITQPRRIAA VTVAKRVAEE CEVELGQKVG
YSIRFDDTTS NLTRLKYMTD GLLLREALLD PHLSRYSVII VDEAHDRSVH TDVLLALLKK
IQRTRSKPTG EKTEIGNLAL EVQTNTRDEN VPQQNGVSRG CQGRKLSPLK LIIMSASLDA
RVFSEYFGGA KAVHVQGRQF PVDILYTVHP ESDYIDAALV TIFQIHLEEK PGDILVFLTG
QDEIESVERL VQERLQHLPE DKRKLLPVPI FSALPSEQQM KAFAPAPTGF RKVILATNIA
ETSITIPGIR YVIDPGFVKA RSYDPRKGME SLDVVPASKA QTLQRSGRAG REVPGKCFRL
YPEREFEKLE DSTKPEIKRC NLSNIILQLK ALGIDDIVGF DFIDRPSSGA IVKALAELHA
LGALTDDGKL EDPAGYQMSR LPLEPIYSKA LILANQYNCL EEMLITVAVL TVESIFYDPR
EKREEARTAK NHFASVEGDH LTYLSVYRES DEFLEKKKVA GSGNNIDKIM KKWCKENFVN
SRSLKHARDI YRQIREHVEQ MGFNVSSCGN DMLEFRRCLA ASFFLKAALR QLDGTYRAME
SGEVVHIHPT SVLFRAKPEC VIFDELMQTS KKYIKNLTRI DPLWLTELAP HHYKTAE
//
