ID S8D0W2_9LAMI Unreviewed; 1164 AA.
AC S8D0W2;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
DE Flags: Fragment;
GN ORFNames=M569_01376 {ECO:0000313|EMBL:EPS73374.1};
OS Genlisea aurea.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Lamiales; Lentibulariaceae; Genlisea.
OX NCBI_TaxID=192259 {ECO:0000313|EMBL:EPS73374.1, ECO:0000313|Proteomes:UP000015453};
RN [1] {ECO:0000313|EMBL:EPS73374.1, ECO:0000313|Proteomes:UP000015453}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23855885;
RA Leushkin E.V., Sutormin R.A., Nabieva E.R., Penin A.A., Kondrashov A.S.,
RA Logacheva M.D.;
RT "The miniature genome of a carnivorous plant Genlisea aurea contains a low
RT number of genes and short non-coding sequences.";
RL BMC Genomics 14:476-476(2013).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC Evidence={ECO:0000256|ARBA:ARBA00001556};
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EPS73374.1}.
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DR EMBL; AUSU01000441; EPS73374.1; -; Genomic_DNA.
DR AlphaFoldDB; S8D0W2; -.
DR OrthoDB; 3682876at2759; -.
DR Proteomes; UP000015453; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:UniProtKB-EC.
DR GO; GO:0000398; P:mRNA splicing, via spliceosome; IEA:InterPro.
DR CDD; cd17971; DEXHc_DHX8; 1.
DR CDD; cd21691; GH2-like_DHX8; 1.
DR CDD; cd05684; S1_DHX8_helicase; 1.
DR CDD; cd18791; SF2_C_RHA; 1.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR044762; DHX8/Prp22_DEXHc.
DR InterPro; IPR049588; DHX8_GH2-like.
DR InterPro; IPR002464; DNA/RNA_helicase_DEAH_CS.
DR InterPro; IPR048333; HA2_WH.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR049621; S1_DHX8_helicase.
DR InterPro; IPR003029; S1_domain.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR PANTHER; PTHR18934:SF85; ATP-DEPENDENT RNA HELICASE DHX8; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF21010; HA2_C; 1.
DR Pfam; PF04408; HA2_N; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF07717; OB_NTP_bind; 1.
DR Pfam; PF00575; S1; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00847; HA2; 1.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00316; S1; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00690; DEAH_ATP_HELICASE; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS50126; S1; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW mRNA processing {ECO:0000256|ARBA:ARBA00022664};
KW mRNA splicing {ECO:0000256|ARBA:ARBA00023187};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000015453}.
FT DOMAIN 207..276
FT /note="S1 motif"
FT /evidence="ECO:0000259|PROSITE:PS50126"
FT DOMAIN 521..684
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 709..882
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 128..204
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 284..312
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 100..127
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 284..300
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EPS73374.1"
SQ SEQUENCE 1164 AA; 132518 MW; 9AFFE16E220B843B CRC64;
DVGLEKLEYL SLVSKVCTEL ESHLGLGEKV LAEFITEMGR NCATVEEFDA KLKENGAEMP
DYFVQTLHTI IHAILPQKQN SKSAKHINEG GNSDFSALKI RDGKERVKQL EKEIEEEAMI
RLKSEREEVY NRSGERYNDR RDKRSDRERE GERDRYRDHD NDDRYERRHS GRDSDSEKHR
HRRGRRDVYD EEPNGDGRNE SSEPELYRVY KGRVSRVMDS GCFVQLDNFR GKEGLVHVSQ
IATRRISNAK DVVKRDQKVY VKVISISGSK LSLSMRDVDQ NSGKDLLPLK RNEEGDGFRT
NPSEVSESND GGVRTRIGLS GINITEVNDS VPSRRPLKKM SSPERWEAKQ LIASGVLSVK
DFPTFDDEGG DGVLYLEEGA EEELEIELNE DEPAFLQGQS HYSIDMSPVK IFKNPEGSLS
RAAALQSALI KERREVREQQ QRTMLDSIPK DLNRPWEDPM PETGERHLAQ ELRGVGLSAY
DMPEWKKDAY GKALTFGQRS KLSIQEQRQS LPIYKLKKEL VQAVHDNQVL VVIGETGSGK
TTQVTQYLAE AGYTTRGKIG CTQPRRVAAM SVAKRVAEEF GCRLGEEVGY AIRFEDCTGP
ETVIKYMTDG MLLREILIDE DLSQYSVIML DEAHERTIHT DVLFGLLKHL VKRRPDLRLI
VTSATLDAEK FSGYFFNCNI FTIPGRTFPV EILYTKQPES DYLDASLITV LQIHLTEPEG
DILLFLTGQE EIDYACQCLY ERMKGLGKNV PELIILPVYS ALPSEMQSRI FDPAPPGKRK
VVVATNIAEA SLTIDGIYYV IDPGFAKQNV YNPKQGLDSL VITPISQASA KQRAGRAGRT
GPGKCYRLYT ESAFHNEMSP TSIPEIQRIN LGTVTLTMKA MGINDLLSFD FMDPPSPQAL
ISAMEQLFSL GALDEEGLLT KLGRKMAEFP LDPPLSKMLL ASVDLGCSDE ILTIIAMIQT
GNIFYRPREK QAQADQKRAK FFQPEGDHLT LLAVYEAWKA KNFSGPWCFE NFVQSRSLRR
AQDVRKQLLS IMDKYKLDVV SAGKNFTKIR KAITAGFFFH ASRKDPQEGY RTLVENQPVY
IHPSSALFQR QPDWVIYHEL VMTTKEYMRE VTVVDPKWLV ELAPRFFKVA DPTKMSKRKR
QERIEPLYDR YHEPNSWRLS KRRA
//
