ID S9RQN6_9RHOB Unreviewed; 524 AA.
AC S9RQN6;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE SubName: Full=Choline dehydrogenase {ECO:0000313|EMBL:EPX80375.1};
DE EC=1.1.99.1 {ECO:0000313|EMBL:EPX80375.1};
GN ORFNames=Salmuc_03691 {ECO:0000313|EMBL:EPX80375.1};
OS Salipiger mucosus DSM 16094.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Salipiger.
OX NCBI_TaxID=1123237 {ECO:0000313|EMBL:EPX80375.1, ECO:0000313|Proteomes:UP000015347};
RN [1] {ECO:0000313|Proteomes:UP000015347}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 16094 {ECO:0000313|Proteomes:UP000015347};
RX PubMed=25197501; DOI=10.4056/sigs.4909790;
RA Riedel T., Spring S., Fiebig A., Petersen J., Kyrpides N.C., Goker M.,
RA Klenk H.P.;
RT "Genome sequence of the exopolysaccharide-producing Salipiger mucosus type
RT strain (DSM 16094(T)), a moderately halophilic member of the Roseobacter
RT clade.";
RL Stand. Genomic Sci. 9:1331-1343(2014).
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974,
CC ECO:0000256|PIRSR:PIRSR000137-2};
CC -!- SIMILARITY: Belongs to the GMC oxidoreductase family.
CC {ECO:0000256|ARBA:ARBA00010790}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EPX80375.1}.
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DR EMBL; APVH01000032; EPX80375.1; -; Genomic_DNA.
DR RefSeq; WP_020038793.1; NZ_KE557277.1.
DR AlphaFoldDB; S9RQN6; -.
DR STRING; 1123237.Salmuc_03691; -.
DR eggNOG; COG2303; Bacteria.
DR HOGENOM; CLU_002865_7_1_5; -.
DR OrthoDB; 9785276at2; -.
DR Proteomes; UP000015347; Unassembled WGS sequence.
DR GO; GO:0008812; F:choline dehydrogenase activity; IEA:UniProtKB-EC.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR Gene3D; 3.30.410.40; -; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR012132; GMC_OxRdtase.
DR InterPro; IPR000172; GMC_OxRdtase_N.
DR InterPro; IPR007867; GMC_OxRtase_C.
DR PANTHER; PTHR11552:SF147; CHOLINE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11552; GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE; 1.
DR Pfam; PF05199; GMC_oxred_C; 1.
DR Pfam; PF00732; GMC_oxred_N; 1.
DR PIRSF; PIRSF000137; Alcohol_oxidase; 2.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827, ECO:0000256|PIRSR:PIRSR000137-2};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Oxidoreductase {ECO:0000313|EMBL:EPX80375.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000015347}.
FT DOMAIN 7..289
FT /note="Glucose-methanol-choline oxidoreductase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00732"
FT DOMAIN 380..507
FT /note="Glucose-methanol-choline oxidoreductase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF05199"
FT BINDING 91..94
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000137-2"
SQ SEQUENCE 524 AA; 55624 MW; A6AA60394B5DA71A CRC64;
MTPTATYDFV IVGAGATGCV VAGHLARRFP EASVLLVEAG RARPGLVNTV PRLGAFAPFR
RGTNWRHTAT LCGREAALFQ GRMPGGSSEI NGMVVSLGAP EDYRPWQEAA GDDWAPETCL
ATMRGLQCRD GAHDAANGKM QTRQLRAPSV LTRAFLDAAA EAGQPVVADL NTRGGPRFGL
VDANIRGVRR HSARAAFLSP WPHNLTLWRG AEAQHFTTDA QGRAQITLRR RRARQTVLTE
AELILAAGAI GTAALLLRSG LGPADVLREA GIEVAQDMPE VGRNLQNHPS FTLRVPTRGD
SLKDLLRPAE GLRALALQAA GRPGPLSEPL FEAAGYFAIP DTAQAAGGQL IMAPVLFPDG
PRPGLPRRHG MTLAIQQGCP ESRGRLVPRA GGGLSIDTGA LDDPRDVEAM GAALAQVQEI
LSRPALAPHL DGRDCLARID ALRLRQEIGT AYHMAGTARM GRDASAPCTP RLRLRAPGRV
RIADASAMPA IPNAALHFPS MMMAARAAAF IAEDHDTPVR PRAA
//
