KEGG   Vulpes vulpes (red fox): 112916728
Entry
112916728         CDS       T05911                                 
Symbol
MTHFD2
Name
(RefSeq) bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial
  KO
K13403  methylenetetrahydrofolate dehydrogenase(NAD+) / 5,10-methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.15 3.5.4.9]
Organism
vvp  Vulpes vulpes (red fox)
Pathway
vvp00670  One carbon pool by folate
vvp01100  Metabolic pathways
vvp01240  Biosynthesis of cofactors
Module
vvp_M00141  C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:vvp00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    112916728 (MTHFD2)
Enzymes [BR:vvp01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.15  methylenetetrahydrofolate dehydrogenase (NAD+)
     112916728 (MTHFD2)
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.9  methenyltetrahydrofolate cyclohydrolase
     112916728 (MTHFD2)
SSDB
Motif
Pfam: THF_DHG_CYH_C THF_DHG_CYH AlaDh_PNT_C PirA-like
Other DBs
NCBI-GeneID: 112916728
NCBI-ProteinID: XP_025850307
UniProt: A0A3Q7RVB3
Position
Unknown
AA seq 350 aa
MAAVSIASTLAIRLLPPARSCRLRHRPFHLSVVRDEAVIISGRKLAQQIKQEVRQEVEEW
VASGNKRPHLSVVLVGENPASHSYVLNKTRAAAEVGINSETIVKPASISEDELLNLINKL
NNDDNIDGLLVQLPLPEHIDERKVCNAVSPDKDVDGFHVINVGRMCLDQYSMLPATPWGV
WEIIKRTGIPTLGKNVVVAGRSKNVGMPIAMLLHTDGAHERPGGDATVTISHRYTPKEQL
KKHTVLADIVISAAGIPNLITADMIKEGAAVIDVGINRVQDPITAKPKLVGDVDFEGVRK
KAGYITPVPGGVGPMTVAMLMKNTIIAAKKVLRLEEREVVKPKERGVASN
NT seq 1053 nt   +upstreamnt  +downstreamnt
atggctgctgtctccatcgcgtccacgttggccatccggctcctcccgccggcgcggagc
tgccgcctccgccatcgccccttccacctctcggtagttcgagatgaagctgtcatcatc
tctggaaggaaacttgcccagcaaatcaagcaggaagtgcggcaggaggtggaagaatgg
gtggcatcaggcaacaagcggccacacctgagtgtggttctggttggtgagaatcctgca
agtcactcctatgtcctcaacaaaaccagggcagctgccgaagtgggaatcaacagtgag
acaattgtgaaaccagcttcaatttcagaggatgaactattgaatttaatcaataaacta
aataatgatgataatatagatggcctccttgttcagctgcctcttccagagcacatcgat
gagagaaaggtctgcaacgctgtttctcctgacaaggatgttgatggttttcatgtaatt
aatgtagggcgaatgtgtctggaccagtattccatgttaccagctaccccatggggtgtc
tgggaaataattaagcgaactggcattccaaccctagggaagaatgtggttgtggctggg
aggtcaaaaaatgttggaatgcccattgcaatgctgctccacacagatggggcacatgaa
cgccctggaggtgatgccacggttacaatatctcatcgatatactcccaaagaacaactg
aagaaacatacagttcttgcagacattgtgatctctgctgcaggcattccaaatctgatc
actgcagatatgatcaaggagggagctgcagtcatcgatgtgggaataaatagagttcaa
gatcccatcactgctaaacccaagttagttggagatgtggattttgaaggagtccgaaag
aaagctggttacatcactccagtccctgggggtgttggtcccatgacagtggcaatgctg
atgaagaataccattattgctgcaaaaaaggtgctgaggcttgaagagcgggaagtagtg
aagcctaaggagcgtggagtagcaagtaattaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (3)   
   KEGG MODULE (1)   
Chemical substance (7)   
   KEGG COMPOUND (7)   
Chemical reaction (4)   
   KEGG ENZYME (2)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (4)   
   Pfam (4)   
All databases (28)   

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