KEGG   Austrofundulus limnaeus (annual killifish): 106530180
Entry
106530180         CDS       T06063                                 
Name
(RefSeq) phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
  KO
K00922  phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
Organism
alim  Austrofundulus limnaeus (annual killifish)
Pathway
alim00562  Inositol phosphate metabolism
alim01100  Metabolic pathways
alim04012  ErbB signaling pathway
alim04068  FoxO signaling pathway
alim04070  Phosphatidylinositol signaling system
alim04081  Hormone signaling
alim04140  Autophagy - animal
alim04145  Phagocytosis
alim04150  mTOR signaling pathway
alim04210  Apoptosis
alim04218  Cellular senescence
alim04370  VEGF signaling pathway
alim04510  Focal adhesion
alim04517  IgSF CAM signaling
alim04518  Integrin signaling
alim04620  Toll-like receptor signaling pathway
alim04625  C-type lectin receptor signaling pathway
alim04810  Regulation of actin cytoskeleton
alim04910  Insulin signaling pathway
alim04914  Progesterone-mediated oocyte maturation
alim05100  Bacterial invasion of epithelial cells
alim05132  Salmonella infection
alim05168  Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:alim00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    106530180
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    106530180
   04370 VEGF signaling pathway
    106530180
   04068 FoxO signaling pathway
    106530180
   04070 Phosphatidylinositol signaling system
    106530180
   04150 mTOR signaling pathway
    106530180
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    106530180
   04517 IgSF CAM signaling
    106530180
   04518 Integrin signaling
    106530180
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagocytosis
    106530180
   04140 Autophagy - animal
    106530180
  09143 Cell growth and death
   04210 Apoptosis
    106530180
   04218 Cellular senescence
    106530180
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    106530180
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    106530180
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    106530180
   04625 C-type lectin receptor signaling pathway
    106530180
  09152 Endocrine system
   04910 Insulin signaling pathway
    106530180
   04914 Progesterone-mediated oocyte maturation
    106530180
 09160 Human Diseases
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    106530180
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    106530180
   05100 Bacterial invasion of epithelial cells
    106530180
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:alim04131]
    106530180
Enzymes [BR:alim01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.153  phosphatidylinositol-4,5-bisphosphate 3-kinase
     106530180
Membrane trafficking [BR:alim04131]
 Endocytosis
  Rab GTPases and associated proteins
   Rab associated proteins
    106530180
SSDB
Motif
Pfam: PI3Ka PI3_PI4_kinase PI3K_C2 PI3K_rbd PI3K_p85B DUF2321 ABC1 Ribosomal_S15
Other DBs
NCBI-GeneID: 106530180
NCBI-ProteinID: XP_013881220
UniProt: A0A2I4CMJ0
Position
Unknown
AA seq 1068 aa
MPPRPSSGELWGMHLMPPSILVDCLLPNGMILTLECLREATLITVKHDLFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDSEVQDFRRNILNVCKEAVDLRDSNGPHSRALYVYPPNVESSAELPRH
IYNKLDKGQIIVVIWVIVSNSNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLTPEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYVRSCIMLGRMPNLMLMSKDSLYCQLPMD
NFTMPSYARRISTATPYMNGETATKCLWTINGTLRIKILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMYIPEIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SCPVKFPDMSIIEEHANWNISRELGFNYGHTGLSNRLARDNPLTESDNEQLRQVCNKDPL
SEITEQEKDFLWSHRYHCVNMPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMMREFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDEAQKVQMKFLVEQMKRPAYTDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHALHQWLKDKNKGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
NT seq 3207 nt   +upstreamnt  +downstreamnt
atgcctcccagaccctcctcaggagagctatgggggatgcacttgatgccccccagcatc
ctagtggactgcctgctgccaaatggcatgattctcacgttggagtgcctccgagaggcc
acgctcatcacggtcaagcacgatcttttcaaagaagccaggaagtaccctctttaccat
ctgctgcaggaggagagctcatacatctttgtcagcgtcacccaggaggcagagcgggaa
gagttctacgacgagactaggaggctgtgcgatctcagactgtttcaggccttcctgaaa
gttattgagccagtgggcaacagagaggagaaaatcctcaacagagagataggttttgct
atcggaatgcccatttgtgagtttgatttggtgaaggactcagaagtgcaggacttcaga
aggaacattttaaatgtttgcaaagaagctgtggacctcagagacagtaacggaccccac
agcagagctttatatgtctatcctcctaatgtagaatcctcagcagaacttcccaggcac
atctataataagctagataaaggtcaaatcattgtggtcatttgggtcattgtttcaaac
agtaatgacaagcaaaagtataccctgaagatcaaccatgattgtgtgccggagcaggtg
atcgccgaagccatccgtaaaaaaacacgaagcatgttgctcaccccggagcagttgaag
atgtgcgtccaggagtatcagggaaagtacatcctcaaggtctgcggctgtgacgagtac
ctcctggagaaatatcccattagtcagtacaagtacgtccgcagctgcatcatgctggga
agaatgcccaacttgatgttgatgtctaaagacagcctttattgccagctgcccatggac
aacttcaccatgccgtcgtacgcgaggcggatatccacggcgacgccctacatgaacggc
gaaacagccaccaagtgtctgtggaccatcaatggaactctgaggatcaagatactctgc
gctacttacgtcaatgtaaacatcagagacattgacaagatctatgtcaggactgggatt
taccatggtggagagcagctgtgtgacaacgtcaacacccaacgtgtgccctgttcaaat
cccaggtggaacgagtggcttaactacgacatgtacattccagaaattcccagagccgcc
cgactctgcctgtccatctgctctgtgaaaggaaggaaaggagctaaagaggagcactgt
cccctggcctggggcaacgtcaacctgttcgactacactcacacattagtagcaggaaag
atggctctcaacctgtggccggttccacatggcctggaggacctgctcaaccccatcggc
gtcacaggctccaacccaaacaaggaaactccctgcctggagctggagtttgaccatttc
agttgtcctgtcaagttcccggacatgagcatcattgaggagcacgcgaactggaacata
tccagagagctcggctttaattacggtcacaccggtttgagcaacagactggcgcgagac
aaccccctgactgagagcgacaacgagcagcttcgacaagtgtgtaacaaagacccgctg
tctgaaatcactgagcaggagaaggacttcctgtggagtcacagataccactgtgtcaac
atgccagagatcctccctaagatcctcctggctgtgaagtggaactccagagatgaggtt
gcacagatgtactgccttctcaaagactggcctgcaataaaaccagaacaagccatggag
ttgctggactgcaactttcccgatcccatgatgagagagtttgctgtgaagtgccttgag
aaatacctgactgatgacaaactctcccagtatctcattcagctggttcaggttctgaag
tacgagcagtaccttgataacccgcttgcacgcttcctgctgaaaaaggcattaaccaat
cagaggataggacatttcttcttctggcatttaaaatcagagatgcacaataagacggtg
agccagcggttcggcctgctgctggagtcgtactgccgggcctgcggtatgtacctgaag
cacctgagcagacaggtggaggccatggagaagctcatcaacctcaccgacatcctcaag
caggagaaaaaagacgaggcgcagaaggttcaaatgaagtttctggtggagcagatgaag
agaccagcctatacggatgcactgcaaagctttacgtccccgctgaatcctgcacatcag
ctgggaaacctccgcctggaggaatgcaggatgatgtcatcggcaaaacggcctctctgg
ctgaactgggaaaaccctgacatgatgtcagagctgctcttccagaacaatgaaatcatc
ttcaaaaacggagacgatctgagacaggacatgctgactctgcagatcattaggataatg
gagaacatctggcagaaccaaggccttgatctcaggatgctgccgtacggctgcctgtcc
atcggtgactgtgtgggtttaatcgaggtggtgaggaattctcacacaatcatgcagatc
caatgcaaaggtggcctgaagggggcgctgcagttcaacagccacgcgctgcatcagtgg
ctgaaggataagaacaagggagagatgtatgaccaggccatcgatctgttcacacggtcg
tgtgccggctactgcgtggccacgttcatcctgggcattggggaccggcacaacagcaac
atcatggtcaaagatgacggacagctgttccacatagacttcggtcatttcctcgaccac
aagaagaagaagtttggctacaagagggagcgtgtaccgtttgtgcttacgcaggacttt
ctgatcgttattagcaaaggaacacaagagtgcacgaaaacaagggagtttgaaaggttc
caggaaatgtgttacaaggcatacttggccatccgccaacacgccaaccttttcatcaac
ctcttctccatgatgctgggctcaggcatgccggagctgcagtcgtttgacgacatcgcc
tacatcagaaagaccctggccctggacaagtcagagcaggaagccctcgactacttcatg
aagcagatgaatgacgcccatcatggcggctggactaccaagatggactggatcttccac
acaattcgccagcacgccatgaactaa

  All links  
Gene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (8)   
   Pfam (8)   
All databases (14)   

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