KEGG   Camelus bactrianus (Bactrian camel): 105076642
Entry
105076642         CDS       T07534                                 
Symbol
CACNA1C
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1C
  KO
K04850  voltage-dependent calcium channel L type alpha-1C
Organism
cbai  Camelus bactrianus (Bactrian camel)
Pathway
cbai04010  MAPK signaling pathway
cbai04020  Calcium signaling pathway
cbai04022  cGMP-PKG signaling pathway
cbai04024  cAMP signaling pathway
cbai04260  Cardiac muscle contraction
cbai04261  Adrenergic signaling in cardiomyocytes
cbai04270  Vascular smooth muscle contraction
cbai04713  Circadian entrainment
cbai04720  Long-term potentiation
cbai04723  Retrograde endocannabinoid signaling
cbai04724  Glutamatergic synapse
cbai04725  Cholinergic synapse
cbai04726  Serotonergic synapse
cbai04727  GABAergic synapse
cbai04728  Dopaminergic synapse
cbai04742  Taste transduction
cbai04911  Insulin secretion
cbai04912  GnRH signaling pathway
cbai04921  Oxytocin signaling pathway
cbai04924  Renin secretion
cbai04925  Aldosterone synthesis and secretion
cbai04927  Cortisol synthesis and secretion
cbai04929  GnRH secretion
cbai04930  Type II diabetes mellitus
cbai04934  Cushing syndrome
cbai04935  Growth hormone synthesis, secretion and action
cbai05010  Alzheimer disease
cbai05020  Prion disease
cbai05022  Pathways of neurodegeneration - multiple diseases
cbai05031  Amphetamine addiction
cbai05207  Chemical carcinogenesis - receptor activation
cbai05410  Hypertrophic cardiomyopathy
cbai05412  Arrhythmogenic right ventricular cardiomyopathy
cbai05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:cbai00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    105076642 (CACNA1C)
   04020 Calcium signaling pathway
    105076642 (CACNA1C)
   04024 cAMP signaling pathway
    105076642 (CACNA1C)
   04022 cGMP-PKG signaling pathway
    105076642 (CACNA1C)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    105076642 (CACNA1C)
   04929 GnRH secretion
    105076642 (CACNA1C)
   04912 GnRH signaling pathway
    105076642 (CACNA1C)
   04921 Oxytocin signaling pathway
    105076642 (CACNA1C)
   04935 Growth hormone synthesis, secretion and action
    105076642 (CACNA1C)
   04924 Renin secretion
    105076642 (CACNA1C)
   04925 Aldosterone synthesis and secretion
    105076642 (CACNA1C)
   04927 Cortisol synthesis and secretion
    105076642 (CACNA1C)
  09153 Circulatory system
   04260 Cardiac muscle contraction
    105076642 (CACNA1C)
   04261 Adrenergic signaling in cardiomyocytes
    105076642 (CACNA1C)
   04270 Vascular smooth muscle contraction
    105076642 (CACNA1C)
  09156 Nervous system
   04724 Glutamatergic synapse
    105076642 (CACNA1C)
   04727 GABAergic synapse
    105076642 (CACNA1C)
   04725 Cholinergic synapse
    105076642 (CACNA1C)
   04728 Dopaminergic synapse
    105076642 (CACNA1C)
   04726 Serotonergic synapse
    105076642 (CACNA1C)
   04720 Long-term potentiation
    105076642 (CACNA1C)
   04723 Retrograde endocannabinoid signaling
    105076642 (CACNA1C)
  09157 Sensory system
   04742 Taste transduction
    105076642 (CACNA1C)
  09159 Environmental adaptation
   04713 Circadian entrainment
    105076642 (CACNA1C)
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    105076642 (CACNA1C)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    105076642 (CACNA1C)
   05020 Prion disease
    105076642 (CACNA1C)
   05022 Pathways of neurodegeneration - multiple diseases
    105076642 (CACNA1C)
  09165 Substance dependence
   05031 Amphetamine addiction
    105076642 (CACNA1C)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    105076642 (CACNA1C)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    105076642 (CACNA1C)
   05414 Dilated cardiomyopathy
    105076642 (CACNA1C)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    105076642 (CACNA1C)
   04934 Cushing syndrome
    105076642 (CACNA1C)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:cbai04040]
    105076642 (CACNA1C)
Ion channels [BR:cbai04040]
 Voltage-gated cation channels
  Calcium channel, voltage-gated (Cav)
   105076642 (CACNA1C)
SSDB
Motif
Pfam: Ion_trans Ca_chan_IQ GPHH CAC1F_C PKD_channel
Other DBs
NCBI-GeneID: 105076642
NCBI-ProteinID: XP_010963192
Position
Unknown
AA seq 2053 aa
MGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISIVEWK
PFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIVFTVEALLKVIAYGLL
FHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRP
LRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYSEEGA
ADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEG
WTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKL
REKQQLEEDLKGYLDWITQAEDIEPENEDEGLDEERPRNMSMPTSETESVNTENVAGGDI
EGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSSIFYWLVIFLVFLNTLTIASE
HYNQPHWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFIVCGGILETI
LVETKVMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIII
FSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMHDGIMAYGGPSF
PGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASP
EKKQEMVEKPAVEETKEEKIELKSITAPGESPPATQINMDDLQPNESEDKASYPRPEATG
EEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSANNRFRLRCHRVVNDSVFTN
LILFFILLSSVSLAAEDPVRHTSFRNHILFYFDIVFTTIFTIEIALKILGNADYVFTSIF
TLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLR
PLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQ
TEAECRGNYITYKDGEVDHPIVQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRS
IDSHTEDKGPIYNYRVEISVFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDK
NQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQS
CLFKIAMNVLNMLFTGLFTVEMLLKLIAFKPKGYFSDPWNVFDFLIVIGSVIDVILSETN
HYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPFMNAEENSRISITFFRLFRVMRL
VKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRN
NNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPGNSTEGETPCGSSFAVFYF
ISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLD
VVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEG
NLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKE
QGLVGKPCQRSALSLQAGLRTLHDLGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIF
RRAGGLFGNHVGYYPSDSRSAFPQTFTTQRPLHISKAGSSQADPESPSHEKLVDSTFTPS
SYSSTGSNANINNANNTALGRSPRPAGDPGAVSTLEGCGTPLSPAVRLQEAAWRHSSKRC
PSRESPIAMVCPEEASRGEARDMQTREDAEFGSEPSLIPTEMLSYQDDESRQLTPPEEDR
RDVRLSPKRGFLRSASLGRRASFHLECLKRQRNHWGDVSQKTVLPLHLVHQQALAVPTPG
APLGARPVSLMVPSPAVARGRQLHGSASSLVEAVLISEGLGKFAQDPKFLEATTQELADA
CDMTIEEMESAADNILSGGAGQSPNGTLLPFANCRDPGPDRAGGTEDAAWAPSPEPPESE
EELLDHGALVSSL
NT seq 6162 nt   +upstreamnt  +downstreamnt
atgggcagcgccggcaacgccaccatctccacggtcagctccacgcagcgcaagcggcag
cagtacggcaaacccaagaagcagggcagcaccacggccacccgcccgccccgcgcgctg
ctctgcctgaccctgaagaaccccatccggagggcctgcatcagcattgtggagtggaag
ccatttgaaatcattattttactgacgatttttgccaattgcgtggccttagccatctac
atccccttcccagaagacgactccaacgccaccaattccaacctggagcgagtggagtac
ctcttcctcatcgttttcactgtggaggcgctgttaaaagtcattgcctacggactcctc
ttccacccgaacgcttacctgcgcaacggctggaatctcctcgacttcatcatcgtggtt
gtcgggctcttctctgccatcttagagcaagccaccaaagcggacggggcgaacgcactc
ggagggaagggggctggattcgacgtgaaggcgctgagggcgttccgcgtgctgcggccc
ctgcggctggtgtccggcgtcccaagcctgcaggtggtcctgaactccatcatcaaagcc
atggtgcccctgctgcacatcgcgctgctggtgctgttcgtcatcatcatctacgccatc
atcggcctggagctcttcatgggaaagatgcacaagacctgctacagcgaggagggcgcc
gcagatgtcccggcagaagacgacccctccccctgcgccctggagacgggccacgggcgc
cagtgccagaatggcacggtgtgcaagccagggtgggacgggcccaagcacggcatcacc
aactttgacaacttcgccttcgccatgctcaccgtgttccagtgcatcaccatggagggc
tggaccgacgtgctgtactgggtcaatgatgccgtgggaagggactggccctggatctat
tttgttacactaatcatcatagggtcattttttgtacttaacttggttctcggtgtcctt
agcggagagttttccaaagagagggagaaggccaaggcccggggcgacttccagaagctg
cgggagaagcagcagctggaggaggacctgaagggctacctggactggatcacgcaggcg
gaggacatagagcccgagaacgaggacgagggcctggacgaggagagaccccgcaacatg
agcatgcccaccagtgagaccgagtcggtcaacaccgaaaacgtggctggaggcgacatc
gagggagaaaactgcggggcccgactggcccaccggatctccaagtccaagttcagccgc
tactggcgccgatggaaccggttctgcaggaggaagtgccgtgcggccgtgaagtcgagc
atcttctactggctggtcatcttcctggtgttcctcaacacgctcaccatcgcctccgag
cactacaaccagccccactggctcacggaggtccaagacacagccaacaaggccctgctg
gccctcttcacggccgagatgctgctcaagatgtacagcctggggctgcaggcctacttc
gtgtcgctcttcaatcgcttcgactgcttcatcgtgtgcggcggcatcctggagaccatc
ctggtggagaccaaggtcatgtccccgctgggcatctccgtgctgagatgcgtccgcctc
ctgcgcatatttaagatcacgaggtactggaactccctgagcaacctggtggcgtccctg
ctgaactcggtgcgctccatcgcctccctgctgctgctgctcttcctcttcatcatcatc
ttctccctcctggggatgcagctcttcggagggaagttcaacttcgacgagatgcagacc
cgcaggagcacgttcgacaactttccgcagtccctgctcaccgtgtttcagatcctgacc
ggggaggactggaactcggtgatgcatgatggcatcatggcttatggcggcccctctttt
ccagggatgctagtctgtatttacttcatcatcctcttcatctgtgggaactatatccta
ctgaatgtgttcttggccattgctgtggacaacctggcagatgctgagagcctcacctct
gcccagaaggaggaggaagaagagaaggagagaaagaagctggccaggactgccagccca
gagaagaaacaagagatggtggagaagccagcagtggaggagaccaaggaggaaaaaatt
gagctgaaatccatcacagcccccggtgagtccccgccagcaacgcagatcaacatggat
gacctccagcccaacgaaagtgaggacaaggcttcctacccccgcccggaagcgacagga
gaggaggacgaggaggagccggagatgccggtgggcccgcgcccgcgccctctctctgag
ctgcacctgaaggagaaggccgtgcccatgccagaagccagcgctttcttcatcttcagc
gccaacaacaggttccgccttcggtgccaccgcgtcgtcaacgactccgtcttcaccaac
ctgatcctcttcttcatcctgctcagcagcgtctccctggccgccgaggacccggtgcgg
cacacctccttcaggaaccacattctgttttattttgacattgttttcactaccattttc
accattgaaattgctctgaagatcctaggcaatgcagactatgtcttcactagtatcttt
acgttagaaattatcctcaagatgaccgcctacggggccttcctgcacaagggctccttc
tgccggaactacttcaacatccttgacctgctggtggtcagcgtgtccctcatctccttc
ggcatccagtccagcgccatcaatgtggtgaagatcctgcgggtcctcagggtgctcagg
cccctccgggccatcaacagggccaaggggctgaagcacgtggtgcagtgcgtgttcgtg
gccatccgcaccatcgggaacatcgtgatcgtcaccacgctgctccagttcatgttcgcc
tgcatcggggtccagctcttcaagggcaagctctacacctgttccgacagctccaagcag
acggaggcggagtgcagggggaactacatcacgtacaaggacggggaggttgaccacccc
atcgtccagccccgcagctgggagaacagcaagtttgacttcgacaacgttctggccgcc
atgatggccctgttcaccgtctccacctttgaggggtggccagagctgctgtaccgctcc
atcgactcccacacggaggacaagggccccatctacaactaccgcgtggagatctccgtc
ttcttcatcatctacatcatcatcatcgccttcttcatgatgaacatattcgtgggcttc
gtcatcgtcaccttccaggagcagggggagcaggagtacaagaactgcgagctggacaag
aaccagcggcagtgcgtggagtacgccctgaaggcccggcccctgcggaggtacatcccc
aagaaccagcaccagtacaaggtgtggtacgtggtcaactccacctacttcgagtacctg
atgttcgtcctcatcctgctcaacaccatctgcctggccatgcagcactacgggcagagc
tgcctgttcaaaatcgccatgaacgtcctgaacatgctcttcaccggcctcttcacagtg
gagatgcttctcaagctcatcgccttcaagcccaagggttactttagtgacccctggaat
gtctttgacttcctcatcgtaattggcagcgtaattgacgtcattctcagtgagacgaat
cactatttctgtgatgcatggaacacatttgacgccttgattgttgtgggtagcattgtt
gatatagcgatcaccgaggtaaacccagctgaacatacccaatgttctccctttatgaac
gcggaggagaactcccgcatctccatcaccttcttccgcctcttccgggtcatgcgcctg
gtcaaactgctgagccgcggggagggcatccggaccctgctgtggaccttcatcaagtcc
tttcaggccctgccctacgtggccctcctgatcgtgatgctcttcttcatctacgccgtc
atcgggatgcaggtgtttgggaaaatcgccctgaacgacacgacggagatcaaccggaac
aacaacttccagaccttcccccaggccgtgctgctgctcttcaggtgtgccacgggtgag
gcctggcaggacatcatgctggcctgcatgcctgggaagaagtgcgcccccgagtcggag
ccaggcaacagcacggagggggagacgccctgcggcagcagcttcgccgtcttctatttc
atcagcttctacatgctgtgtgccttcctgatcatcaacctctttgtggccgtcatcatg
gacaactttgactacctgacccgggactggtccatcctgggtccccaccacttggacgag
tttaagagaatctgggcggagtacgaccctgaagccaagggccgcatcaaacacctggat
gtggtgacgctgctgcggcgcatccagcccccgctgggtttcgggaagctgtgccctcac
cgcgtggcctgcaaacgcctggtctccatgaacatgcctctcaacagcgacgggacggtc
atgttcaacgccacgctgttcgccctggtccggacagccctgaggatcaaaacggaaggg
aacctggagcaggccaacgaggagctgcgggccatcatcaagaagatctggaagcggacg
agcatgaagctgctggaccaggtggtgccgcccgcaggagacgacgaggtcacggtcggc
aagttttacgccaccttcctgatccaggagtacttccggaagtttaagaagcgcaaagag
cagggcctcgtgggcaagccctgccagaggagcgccctgtccctgcaggctggcctgcgc
accctgcatgacctggggcccgagatccgcagggccatctccggggacctgacggccgag
gaggagctggacaaagccatgaaggaggcggtgtccgcagcctcggaggacgacatcttc
aggagggccggaggcctgttcggcaaccacgtcggctactaccccagcgacagccggagc
gccttcccgcagaccttcaccacgcagcggcccctgcacatcagcaaggcgggcagcagc
caggccgaccccgagtcgccctcccacgagaagctagtggactccaccttcacacccagc
agctactcatccacgggctccaacgccaacatcaacaatgccaacaacacggccctgggc
cgcagcccccgccccgccggcgacccgggggctgtcagcacgctggagggctgcgggacc
cccttgtcccccgccgtccggctgcaggaggccgcgtggaggcacagctccaagaggtgc
ccctcccgggagagtccgatagccatggtgtgcccagaggaggcctctcggggcgaggcc
cgtgacatgcagacgcgtgaggacgcggagttcggcagcgagcccagcctgatccccacc
gagatgctctcctatcaggatgacgagagccgacagctgacaccccccgaggaggacagg
agggacgtccggctatctccaaagagaggcttcctgcgctccgcctccctaggtagaagg
gcctccttccacctggagtgtctgaagcggcagaggaatcactggggagacgtctctcag
aagacggtcctgcccttgcacctggttcaccagcaggcattggcagtgcccacgccgggt
gcccccctgggagcccggcctgtgtccctgatggtgcccagcccagcggtggcccggggc
cgccagctccacggcagcgccagcagcttggtggaagcggtcttgatctcggaaggactg
ggaaagtttgctcaggaccccaagttcctggaggccaccacgcaagagctggcagacgcc
tgcgacatgacgatagaggagatggagagtgcggccgacaacattctcagcgggggcgcc
gggcagagccccaacggcaccctgcttccttttgcaaactgcagggacccggggccggac
agagcggggggcacggaggatgcggcctgggcgcccagccccgagccccctgagagcgag
gaggagctcctggaccatggggccttggtcagcagcctgtag

  All links  
Gene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (19)   
   RefSeq(pep) (19)   
DNA sequence (23)   
   RefSeq(nuc) (19)   
   GenBank (2)   
   EMBL (2)   
Protein domain (5)   
   Pfam (5)   
All databases (49)   

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