KEGG   Danio aesculapii (panther danio): 130237220
Entry
130237220         CDS       T11734                                 
Symbol
pik3ca
Name
(RefSeq) phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
  KO
K00922  phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
Organism
daes  Danio aesculapii (panther danio)
Pathway
daes00562  Inositol phosphate metabolism
daes01100  Metabolic pathways
daes04012  ErbB signaling pathway
daes04068  FoxO signaling pathway
daes04070  Phosphatidylinositol signaling system
daes04081  Hormone signaling
daes04140  Autophagy - animal
daes04145  Phagocytosis
daes04150  mTOR signaling pathway
daes04210  Apoptosis
daes04218  Cellular senescence
daes04370  VEGF signaling pathway
daes04510  Focal adhesion
daes04517  IgSF CAM signaling
daes04518  Integrin signaling
daes04620  Toll-like receptor signaling pathway
daes04625  C-type lectin receptor signaling pathway
daes04810  Regulation of actin cytoskeleton
daes04910  Insulin signaling pathway
daes04914  Progesterone-mediated oocyte maturation
daes05100  Bacterial invasion of epithelial cells
daes05132  Salmonella infection
daes05168  Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:daes00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    130237220 (pik3ca)
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    130237220 (pik3ca)
   04370 VEGF signaling pathway
    130237220 (pik3ca)
   04068 FoxO signaling pathway
    130237220 (pik3ca)
   04070 Phosphatidylinositol signaling system
    130237220 (pik3ca)
   04150 mTOR signaling pathway
    130237220 (pik3ca)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    130237220 (pik3ca)
   04517 IgSF CAM signaling
    130237220 (pik3ca)
   04518 Integrin signaling
    130237220 (pik3ca)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagocytosis
    130237220 (pik3ca)
   04140 Autophagy - animal
    130237220 (pik3ca)
  09143 Cell growth and death
   04210 Apoptosis
    130237220 (pik3ca)
   04218 Cellular senescence
    130237220 (pik3ca)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    130237220 (pik3ca)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    130237220 (pik3ca)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    130237220 (pik3ca)
   04625 C-type lectin receptor signaling pathway
    130237220 (pik3ca)
  09152 Endocrine system
   04910 Insulin signaling pathway
    130237220 (pik3ca)
   04914 Progesterone-mediated oocyte maturation
    130237220 (pik3ca)
 09160 Human Diseases
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    130237220 (pik3ca)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    130237220 (pik3ca)
   05100 Bacterial invasion of epithelial cells
    130237220 (pik3ca)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:daes04131]
    130237220 (pik3ca)
Enzymes [BR:daes01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.153  phosphatidylinositol-4,5-bisphosphate 3-kinase
     130237220 (pik3ca)
Membrane trafficking [BR:daes04131]
 Endocytosis
  Rab GTPases and associated proteins
   Rab associated proteins
    130237220 (pik3ca)
SSDB
Motif
Pfam: PI3Ka PI3_PI4_kinase PI3K_C2 PI3K_rbd PI3K_p85B DUF2321 ABC1 Ribosomal_S15
Other DBs
NCBI-GeneID: 130237220
NCBI-ProteinID: XP_056324070
Position
11:complement(34849058..34883948)
AA seq 1069 aa
MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH
LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDASGAHSRALYVYPPNVESSPELPKH
IYGKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSAEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPISQYKYVRSCIMLGRLPNLMLMSKDSLYSQLPMD
NFTMPSYARRISTATPYMNGEASTKSLWTINSTLRIRVLCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNVNLFDYTHTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDYF
SSPVKFPDMATIEDHANWIISREMGYNYCQSGQSSRVARDHAMTETDIEQLRQLGNRDPL
SEITEQEKDFLWRHRQYCVNIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNYPDPMIRDFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDYMDALQNFTSPLNPAHQLGNLRLEDCRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSSTLHQWLKDKNKGEMYDMAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDI
AYIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRHHAQN
NT seq 3210 nt   +upstreamnt  +downstreamnt
atgcctccaagaccctcttcaggagagttatggggcatccatttgatgccccccaggatt
ttggtggactgtctgctgcccaatggcatgatcctgacactagagtgcctccgggaggct
acactcataacaatcaaacatgagctgtttaaggaggctaggaaatacccccttcaccac
cttctgcaggaggaaacctcttatatttttgtcagtgtaacgcaagaggcagagcgagaa
gagttctacgatgagaccaggagactctgcgaccttcggcttttccagccgttcctaaag
gtcatcgaacctgtagggaacagagaggaaaagatcctcaacagagaaattggttttgcc
attggcatgccagtgtgtgagtttgatctagtgaaggatcctgaggtgcaggacttcagg
agaaatatccttaatgtctgcaaggactcagtagagttgcgggatgccagcggggcacac
agtcgagcactatacgtttatcctcctaacgtggagtcttcaccagagcttccaaagcat
atatatggcaaattagacaagggtcaaatcattgtggtcatctgggtgatcgtctcgccc
aacaacgacaagcagaagtacacactaaagatcaatcatgactgcgtacctgagcaggtg
atcgccgaagccatcaggaagaaaaccagaagcatgctgctgtccgccgagcagctaaag
atgtgcgttcaggaatatcagggcaaatacatcctgaaggtctgcggctgtgacgagtat
cttttggaaaagtaccccatcagtcagtacaagtatgtacggagttgcattatgctgggt
cgcttgccaaacctcatgcttatgtccaaggacagtctttactctcagctgccgatggac
aacttcaccatgccctcctatgcccgccgaatttccaccgcaacgccttacatgaacgga
gaggcctccaccaaatctctttggaccattaacagcacccttaggatacgggtcctctgc
gcaacatacgttaatgtgaacattcgggacattgacaagatttacgtgcggacagggatc
taccatggtggagaacagttgtgtgataatgtcaacacgcagcgtgtcccgtgttcaaat
ccgaggtggaacgagtggttgacttatgacatgtacattcctgacatcccccgggcggct
cgtctctgtctctccatctgttctgtgaaaggaaggaagggggcaaaagaggagcattgt
ccactggcctggggaaacgtcaatctgtttgactacacacacactctggtctcaggaaag
atggcactgaatctgtggcccgtaccacacggcctagaagacctgcttaaccccatcggt
gtcacaggctccaaccctaacaaggaaaccccatgtttagagctggagtttgactatttc
agctcacctgttaagttccctgacatggctacaattgaggatcacgctaactggataata
tccagagagatgggatacaattactgccagtctggacagagcagtagagtggcgcgagac
catgcaatgacagagacagatatagagcaacttcggcagctgggcaacagggacccactt
tctgagatcactgagcaggaaaaagacttcctatggaggcacaggcagtattgtgtaaat
ataccagaaatcctgcccaagattctgctggcggtgaagtggaattccagagatgaagtt
gcacagatgtattgccttctgaaagattggcctgcaataaagccagaacaagccatggag
ttgcttgactgtaactaccctgatccaatgatccgagactttgcggttaggtgccttgag
aagtatctaaccgatgacaaactctcgcagtacctcattcagttggttcaggttttgaag
tacgagcagtatcttgataacccactggtgcgatttctgttaaaaaaggctctcaccaac
cagaggattgggcacttcttcttttggcatttgaagtcagagatgcacaataaaacagtg
agtcagcggtttggcctgctgctggagtcgtactgccgcgcatgtggcatgtatctgaag
cacctgagcagacaggtggaggccatggagaagctcatcaacctcacagacattctcaaa
caggagaagaaggatgaaactcagaaggtgcaaatgaagtttctagtggagcagatgagg
cggccggactacatggatgccctccaaaatttcacctctccactaaatcctgcccaccag
ctggggaacctacgacttgaagactgcagaatcatgtcctctgccaagagaccgctctgg
ctgaactgggaaaatcctgacatcatgtccgaacttctcttccaaaacaatgagatcatc
ttcaagaacggggatgatctgcggcaagacatgttgacacttcagatcatcagaataatg
gagaacatttggcaaaatcagggtctggacctgagaatgctcccctatggctgcttgtct
attggagattgtgttggtctcatcgaggtagtaagaagttcacacaccatcatgcagatt
cagtgtaaaggaggcctgaagggtgcgctgcagtttaacagttcaacgctgcatcagtgg
ctaaaggacaagaacaagggtgaaatgtacgacatggctatagacttgtttacgcgatcc
tgcgctggctattgtgtggccactttcattctgggcatcggtgacaggcacaacagtaac
atcatggtgaaggatgatgggcagctgtttcatatagattttggtcactttttggaccac
aagaagaagaaatttggctacaagcgagagcgagtgccgttcgtcttaactcaagacttc
ctaattgtgatcagcaaaggaggaacccaggagtgcactaaaacccgagagtttgagagg
tttcaagagatgtgctacaaggcatacctggccatccgacagcatgccaacctcttcatc
aacctcttctccatgatgctgggctcaggaatgccggagctgcagtccttcgatgacatc
gcttacatccgcaagactctggcattggacaaaaccgagcaggaggccctggactatttc
atgaagcagatgaatgacgctcaccatggcggatggaccaccaagatggactggatcttc
cacaccatccgacaccatgcccaaaactga

  All links  
Gene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (8)   
   Pfam (8)   
All databases (12)   

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