KEGG   Eublepharis macularius (Leopard gecko): 129329616
Entry
129329616         CDS       T09084                                 
Symbol
CACNA1S
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1S isoform X1
  KO
K04857  voltage-dependent calcium channel L type alpha-1S
Organism
emc  Eublepharis macularius (Leopard gecko)
Pathway
emc04010  MAPK signaling pathway
emc04020  Calcium signaling pathway
emc04260  Cardiac muscle contraction
emc04261  Adrenergic signaling in cardiomyocytes
emc04270  Vascular smooth muscle contraction
emc04912  GnRH signaling pathway
Brite
KEGG Orthology (KO) [BR:emc00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    129329616 (CACNA1S)
   04020 Calcium signaling pathway
    129329616 (CACNA1S)
 09150 Organismal Systems
  09152 Endocrine system
   04912 GnRH signaling pathway
    129329616 (CACNA1S)
  09153 Circulatory system
   04260 Cardiac muscle contraction
    129329616 (CACNA1S)
   04261 Adrenergic signaling in cardiomyocytes
    129329616 (CACNA1S)
   04270 Vascular smooth muscle contraction
    129329616 (CACNA1S)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:emc04040]
    129329616 (CACNA1S)
Ion channels [BR:emc04040]
 Voltage-gated cation channels
  Calcium channel, voltage-gated (Cav)
   129329616 (CACNA1S)
SSDB
Motif
Pfam: Ion_trans GPHH Ca_chan_IQ PKD_channel CAC1F_C
Other DBs
NCBI-GeneID: 129329616
NCBI-ProteinID: XP_054835080
UniProt: A0AA97JCC3
Position
5:complement(104231057..104311048)
AA seq 1834 aa
MDPTSVQDDIQKKKQQKEKAKKAALEAPPRPLRSLFCLTLQNPVRKACIAIVEWKPFETI
ILLTIFANCVALAIYLPMPEDDSNKVNSRLEKLEYFFLIVFTIEAALKIIAYGFLFHADA
YLRNGWNVLDFTIVFLGVFTVIMEKISVMESALLSGQGGFDVKALRAFRVLRPLRLVSGV
PSLQVVLNSIIKAMLPLLHIAVLVVFMLIIYAIVGEELFKGKMHKTCYYIGTDIIATVEN
EVPSPCTNSGHGRHCSINGSECRGWWPGPNNGITHFDNFGFAMLTVYQCISMEGWTSVLY
WVNDAIGNEWPWIYFVSLILLGSFFILNLILGVLSGEFTKEREKAKSRGTFQKLREKQQL
EEDMKGYMDWITHAEVIDSDRTRGEGMMPLDEGGSETESLYEIEGMNKWILFFRHWRRWN
RLLRRKCREVVKSKFFYWFVILIVSLNTLSIASEHHNQPGWLTHVQDIANRVLLALFTVE
MILKMYALGLRQYFMSIFNRFDCLVVCTGILELILVEIISMTPLGISVLRCIRLLRIFKI
TKYWTSLNNLVASLLNSVRSIASLLTLLFLYIVIFALLGMQLFGGRFDFDDTEIRRSTFD
NFPQAFISVFQVLTGEDWTSIMYNGIMAYGGPSYPGMLVCIYFIVLFVCGNYILLNVFLA
IAVDNLAEAETLTSAQKAKAEEKKRKKMSRGYPEKSDEEKQMLAKKLEQKAKGEGIPTTA
KLKVDEFESNVNEVKDPYPSADFPGDDEEDEPEIPLSPRPRPLAELQLKEKAVPMPEASA
FFIFSPTNKIRVLCHRIVNATWFTNFILLFILLSSISLAAEDPIRAESFRNKILGYFDIG
FTSVFTVEIVLKMTAYGAFLHKGSFCRNYFNILDLLVVAVSLISMGLESSAISVVKILRV
LRVLRPLRAINRAKGLKHVVQCVFVAIKTIGNIVLVSALLQFMFACIGVQLFKGKFYSCT
DPLKMTEKECWGQFITYVDADPTQVVLHERVWFHNEFHFDNVLSAMMSLFTVSTFEGWPQ
LLYKAIDTHSEDMGPIYNYRMGIATYFIIYLILIAFFMMNIFVGFIIVTFQEQGETEYKN
CELDKNQRQCVQYALKARPLKCYIPKNPYQYQIWYVVTSSYFEYLMFFLITLNTICLGMQ
HYNQSETMNQVSDVLNVVFTILFTVEMILKLIAFKAKGYFGDPWNVFDFLIVIGSIIDVI
LSQIDPPSTGNEENGRVSITFFRLFRVLRLVKLLSRGEGIRNLLWTFIKSFQALPHVALL
IVMLFFVYAVIGMQMFGKVALVDGTQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLAAS
YGKPCDPESDYAPGEEYTCGTNFAYFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSI
LGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKFCPHRVACKRLVGMNM
PLNSDGTVTFNATLFALVRTALKIKTEGNFEQANEELRMIIKKIWKRTSMKLLDQVIPPI
GDDEVTVGKFYATFLIQEHFRKFMKRQEEYYGYRPKKNAVEIQAGLRTIEEEAAPEIRRA
ISGDLTAEEELERAIVEAAIEEGIYRRTGGLFGHVDTFIEPSSPLPPHVASQRPLQFTEV
GSEDLDSPVFLDDFPPDGHANVNNSNSNANNNTTACFLPRMTYENELRGEKLLPPFHQPL
VLANKGSLQPEKLPRKMSQMPKHGGTSCSELQLAMHQSPKQKPTKSEQEAEEEEVLQSSH
TSERNASGDMEANTPANLQLIQKALISGGLSFLVKDYSFLKLVQDEMAAAIQMEVTEMEE
AAAILLNSKKHLATSLCRSRSLASSSEAIPDTRM
NT seq 5505 nt   +upstreamnt  +downstreamnt
atggatcccacttctgtccaggatgatatccagaagaaaaagcaacagaaagaaaaagca
aagaaagcagcactggaagctccccccaggccactccggtccctgttctgcctcacactc
cagaacccagtgcgcaaggcctgcatcgctatcgtggaatggaagcccttcgagaccatc
atcctgctaacgatctttgccaattgtgtggcactggctatctacctgcctatgccggaa
gatgactccaacaaagtcaactccagactggagaagctagaatacttctttctgattgtg
tttaccattgaggcagcattaaagatcatagcctatggatttctattccacgcagatgcc
tacctacgaaatggctggaatgtactggatttcaccatcgtctttttaggagtcttcaca
gtgatcatggaaaaaatcagcgtaatggagagtgctcttctcagtgggcagggcggtttt
gatgtcaaagctctgagagcctttcgtgtgctacggcccctacgcttggtgtcgggagtg
ccaagcctgcaagtggtactgaactctattatcaaagccatgttgccactgctccacatt
gctgtgcttgttgtcttcatgctgatcatctatgccatagtaggggaagaactcttcaag
ggcaaaatgcacaagacttgttactacattgggacagacatcattgccacagtagaaaat
gaagtaccatctccatgtacaaactcaggccatgggcgccattgctccatcaatggctct
gaatgcagaggctggtggccaggacccaacaatggcatcacccactttgacaactttggg
tttgctatgctgactgtctaccagtgtatctccatggagggttggacttcagtcctttac
tgggtcaatgatgcaattgggaatgagtggccctggatctactttgtcagcctcatctta
cttgggtcattttttatcctcaacctgatattgggggtgctcagtggggagttcaccaaa
gagcgtgagaaagccaaatcacgaggtacgttccagaaactgagggagaagcagcaatta
gaggaggacatgaagggctacatggattggattactcatgcagaagtcatagacagtgac
cggacccgtggtgaagggatgatgccgttggatgaaggtggctcagagaccgagagcctg
tatgaaatcgagggcatgaataaatggatcctcttcttccggcattggcggcgatggaac
cgtcttttacgtcggaaatgtcgtgaagtggttaagtccaagtttttctactggtttgtg
atcctgattgtctccttgaacactctctcaatagcatctgagcatcacaatcagcctggc
tggctgacccacgtacaagatattgccaaccgggtgctgctggctctctttacagtagag
atgattctgaagatgtatgccttgggtctgcgccagtacttcatgtccatcttcaaccgt
tttgattgcctggtggtttgcactggcattctggagctcatactggtggagattatttcc
atgactcctctgggcatctcagttttgaggtgcattcgtctgttgaggattttcaagata
accaaatattggacctctctgaacaacttggtggcatctttgctgaattcagtgcgctcc
attgcctccctcctcaccctcctcttcctgtacattgtcatcttcgcacttttagggatg
caactttttggaggcaggtttgactttgatgatacggagatacgccgtagcacctttgat
aactttcctcaggctttcatcagcgtcttccaggtcctgactggggaagactggacttct
ataatgtataatggaattatggcctatggaggaccatcataccccggtatgctggtctgc
atttatttcattgttctctttgtctgcgggaattatattttgctcaatgtcttcttggcc
attgctgtggataaccttgctgaagctgaaactttgacttctgctcagaaagccaaagct
gaagagaaaaagagaaagaaaatgtccagaggttaccctgagaaatcagatgaggaaaaa
cagatgctggctaagaagctggaacagaaagccaagggagaaggaatccctaccacagcg
aagttgaaagtagatgaatttgagtccaatgtcaatgaggtcaaggacccttatccctct
gctgacttcccaggtgatgatgaagaagatgaacctgaaatcccactgagtcctcggcca
cgtccactagcagaactgcagttgaaggagaaggcagtgcccatgcctgaagccagtgca
ttcttcatatttagcccaaccaacaagattcgtgtactgtgccaccggattgtcaacgcc
acctggttcaccaacttcattcttctcttcatcctgctcagcagcatctcactggcagct
gaagaccccatcagagctgagtccttcaggaataagattctaggatattttgacattggc
ttcacttctgtatttacagtggaaatagttctaaagatgaccgcttatggtgccttcctt
cataaaggctccttttgccgcaactacttcaacatcctggacttgcttgtggtagctgtt
tctctcatctccatgggacttgaatccagtgccatctcagtggtgaaaatcctaagggtt
ctcagagtactgcgaccgctgagagccattaacagagcaaagggcctaaagcatgtagtc
cagtgcgtttttgtggccatcaagaccatcggcaacattgtacttgtctccgccttattg
cagttcatgtttgcctgcattggggtgcagcttttcaagggcaagttctacagctgcaca
gatccactcaagatgactgaaaaggagtgctgggggcagttcatcacatatgttgatgct
gatccaacgcaggttgttcttcatgagcgagtatggtttcataatgaattccacttcgac
aatgtgttgtcagccatgatgtctctcttcaccgtatccacctttgagggatggccccag
ctgctatacaaagccattgacacccacagtgaggacatgggccccatatacaactatcgc
atgggcattgccacctacttcatcatctatctcatcctcatagcctttttcatgatgaac
atcttcgtaggctttatcattgtaaccttccaggagcaaggggaaacagagtacaaaaac
tgtgaactggacaagaatcagcgtcagtgtgttcagtatgcactgaaagcacggcctttg
aaatgctacattcctaagaacccctaccagtaccagatatggtacgtggtgacctcctcc
tattttgagtatctcatgttcttcctgatcacattgaacaccatctgcttaggcatgcag
cattacaatcaatcggaaacaatgaaccaggtctccgatgtcctcaatgtggtctttact
atcctctttactgtggagatgattcttaaacttatagccttcaaggctaagggctacttt
ggggacccctggaatgtctttgatttcctcattgttattggcagcatcattgatgtcatc
cttagtcagattgatcctccttccacaggtaatgaggagaatgggcgagtgtcaatcacc
ttttttcggcttttccgtgtactaaggctggtaaaattgctgagccgaggagaaggcatc
agaaacttactctggaccttcatcaagtccttccaggccctgcctcatgttgccctgttg
attgtgatgctgttctttgtctatgctgtgattgggatgcaaatgtttgggaaagttgct
ctagtggatggaacccaaatcaatcggaataacaattttcagaccttcccgcaagcggtg
ctgctgctgttcaggtgtgcaacaggtgaggcttggcaagagattatgctggctgccagc
tatgggaagccgtgtgaccctgagtctgactatgcccccggggaagaatacacttgtggc
acaaacttcgcttatttctacttcatcagtttctacatgctgtgtgcattcctgattatc
aacctctttgttgctgtcatcatggacaactttgattacctcacacgggactggtccata
ctgggtccacatcatctggatgaattcaaaagaatctgggcagaatatgaccctgaagcc
aaggggcgcatcaaacatctagatgtggtgactttgttgagacgaatccagcctcctctg
ggctttgggaagttttgtccacatcgtgtggcttgcaagcgcctggtgggcatgaatatg
cccctgaatagtgatggtaccgtcactttcaatgccacgctctttgctctggtgagaaca
gctctcaagatcaagacagaaggtaactttgaacaagctaatgaagaactaaggatgatt
atcaaaaaaatctggaagagaacaagcatgaagctcctggatcaagtcattccaccaatt
ggtgatgatgaggtgactgtgggcaagttctatgctaccttcctcatacaggaacacttc
aggaaattcatgaaacggcaggaagagtattatggataccggcccaagaagaacgctgtt
gagatccaggctggtctgagaaccattgaagaagaagctgctcctgagatccgtagagca
atctctggggatctgactgcagaggaagagcttgagagagccatagtggaggcagcaata
gaggaaggcatctataggaggacaggaggtttgtttggccacgtggacaccttcatagaa
cccagcagtcccctgccgcctcatgtggctagccagagacccctacagttcacagaagtg
gggagtgaagatttagattctcccgtcttccttgatgacttcccaccagacgggcatgcc
aatgtgaacaacagcaacagcaatgccaacaacaacacgacagcatgttttctccctagg
atgacatatgaaaacgagctgaggggagagaagttgctaccaccatttcatcagccactt
gtcctggccaacaaaggctcccttcagcctgaaaagctaccaaggaaaatgagccagatg
ccaaaacatggtggcacaagctgttcagaactacagcttgccatgcaccagtcgcccaaa
cagaagccgactaagtctgagcaagaggcagaggaagaggaagtgctacaatctagccat
accagtgaaagaaacgcatcaggggacatggaagccaataccccagctaatctccagctt
attcaaaaggctctgatctctgggggactcagcttccttgtcaaagactattcatttttg
aaactggtacaagatgagatggctgctgccatccagatggaggtgacagaaatggaggag
gctgctgcaattttgttgaatagcaagaaacacttggctacgtctctgtgcaggtcccgt
agcttggccagctcctcagaggccattccagatacccgaatgtga

  All links  
Gene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (4)   
   UniProt (1)   
   RefSeq(pep) (3)   
DNA sequence (3)   
   RefSeq(nuc) (3)   
Protein domain (5)   
   Pfam (5)   
All databases (14)   

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