KEGG   Eublepharis macularius (Leopard gecko): 129334239
Entry
129334239         CDS       T09084                                 
Symbol
PIK3R1
Name
(RefSeq) phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1
  KO
K02649  phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
Organism
emc  Eublepharis macularius (Leopard gecko)
Pathway
emc04012  ErbB signaling pathway
emc04068  FoxO signaling pathway
emc04070  Phosphatidylinositol signaling system
emc04081  Hormone signaling
emc04140  Autophagy - animal
emc04145  Phagocytosis
emc04150  mTOR signaling pathway
emc04210  Apoptosis
emc04218  Cellular senescence
emc04370  VEGF signaling pathway
emc04510  Focal adhesion
emc04517  IgSF CAM signaling
emc04518  Integrin signaling
emc04620  Toll-like receptor signaling pathway
emc04625  C-type lectin receptor signaling pathway
emc04810  Regulation of actin cytoskeleton
emc04910  Insulin signaling pathway
emc04914  Progesterone-mediated oocyte maturation
emc05100  Bacterial invasion of epithelial cells
emc05168  Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:emc00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    129334239 (PIK3R1)
   04370 VEGF signaling pathway
    129334239 (PIK3R1)
   04068 FoxO signaling pathway
    129334239 (PIK3R1)
   04070 Phosphatidylinositol signaling system
    129334239 (PIK3R1)
   04150 mTOR signaling pathway
    129334239 (PIK3R1)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    129334239 (PIK3R1)
   04517 IgSF CAM signaling
    129334239 (PIK3R1)
   04518 Integrin signaling
    129334239 (PIK3R1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagocytosis
    129334239 (PIK3R1)
   04140 Autophagy - animal
    129334239 (PIK3R1)
  09143 Cell growth and death
   04210 Apoptosis
    129334239 (PIK3R1)
   04218 Cellular senescence
    129334239 (PIK3R1)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    129334239 (PIK3R1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    129334239 (PIK3R1)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    129334239 (PIK3R1)
   04625 C-type lectin receptor signaling pathway
    129334239 (PIK3R1)
  09152 Endocrine system
   04910 Insulin signaling pathway
    129334239 (PIK3R1)
   04914 Progesterone-mediated oocyte maturation
    129334239 (PIK3R1)
 09160 Human Diseases
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    129334239 (PIK3R1)
  09171 Infectious disease: bacterial
   05100 Bacterial invasion of epithelial cells
    129334239 (PIK3R1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:emc04131]
    129334239 (PIK3R1)
Membrane trafficking [BR:emc04131]
 Endocytosis
  Rab GTPases and associated proteins
   Rab associated proteins
    129334239 (PIK3R1)
SSDB
Motif
Pfam: PI3K_P85_iSH2 SH2 RhoGAP SH3_1 SH2_1 AAA_13 CEP135_TSGA10_CC CCDC113_CCDC96_CC SH3_2 SH3_9 Imm6 ODF2_C FBXO32_helical V_ATPase_I Laminin_I
Other DBs
NCBI-GeneID: 129334239
NCBI-ProteinID: XP_054842146
UniProt: A0AA97L511
Position
8:37847054..37908452
AA seq 724 aa
MSAEGYQYRALYDYKKEREEDIDLHLGDILTVNKGTLVALGFSEGEEAKPEEIGWLSGFN
ETTGERGDFPGTYVEYIGRKKISPPTPKPRPVRPLPVAPSPAKVGTDNDQPALLLPDLSE
QFSPPDNAPPLLVKLVEAIERKGLECSTLYRTQGSSSIVELRQITECDVSTVDFDAIDLQ
ILQDALKRYFLDLPNPVIPASVYTELISTAQEAQNSEDSAQVLKRLIRSSNIPQQYWLTL
QYLLKHFSRLCQSSAKNLLNARSLAEIFSTLLFRSQVASADNIEYHIKMLELLITNEWNE
RQPAPALPPKPPKPNTVTNNGMNNNMSLQDAEWYWGDISREEVNEKLRDTADGTFLVRDA
STKMHGDYTLTLRKGGNNKLIKIFHRDGKYGFSDPLTFNSVVELINHYRNESLAQYNPKL
DVKLLYPVSKYQQDQVVKEDSIEAVGKKLHEYNIQFQEKNREYDRLYEDYTRTSQEIQMK
RTAIEAFNETIKIFEEQCQTQERYSKEYIEKFKREGNEKEIQRIMHNYEKLKSRISEIVD
SRRRLEEDLKKQAAEYREIDKRMNSIKPDLIQLRKTRDQYLMWLTQKGVRQKKLNEWLGN
ENTEDQYSMVEDDEDLPHQDERTWNVGNINRSQAENLLRGKRDGTFLVRESSKQGCYACS
VVVDGEVKHCVINKTPTGYGFAEPYNLYNTLRELVLHYQHTSLVQHNDSLNVTLAYPVYA
QQRR
NT seq 2175 nt   +upstreamnt  +downstreamnt
atgagtgcagaaggataccagtacagagctttatatgattacaaaaaagaacgagaagaa
gacattgacttgcacttgggagatattttaactgtgaataaaggtactttagttgctctt
ggattcagcgaaggagaagaggcaaaacctgaggaaattggttggttgagtggctttaat
gaaactactggagaaagaggggacttcccaggaacttatgtcgaatatattggaagaaaa
aaaatttctccccctactccaaagcctcgccctgttcgaccccttcctgttgcaccaagt
cctgcaaaagtaggaacagacaatgatcagccagctcttttactcccagatctttctgaa
cagttttcaccacctgataatgctccacctctccttgtcaagttagtggaagccattgaa
agaaaaggactggaatgttcgacattgtacaggacacaagggtcaagcagcattgtggaa
ttaagacaaatcacagagtgtgatgtttcgacagtggattttgatgccattgatctgcag
attttacaagatgctttgaagaggtactttttggacctgccaaatcctgtcattccagca
tctgtttacactgaactgatttccacagcacaagaagcgcagaactcagaggactctgct
caggtgctgaagaggctcatcagatcatctaatatacctcaacagtattggctcaccctc
caatatctgctcaaacatttctccagactttgtcagagttctgccaaaaatcttttgaat
gcaagatcattggctgaaatttttagcactctgctgttcaggtcccaggtagcaagcgct
gacaatattgaataccacatcaagatgttggaactgttaattacaaatgaatggaacgag
agacaacctgccccagcactgcctcctaaacctccaaaaccaaatactgtaacaaataat
ggtatgaataacaacatgtctctgcaagatgctgaatggtactggggagatatctcaagg
gaggaagtaaatgagaagcttcgcgacactgctgatggtaccttcttggtacgagatgcc
tccaccaaaatgcatggagactatacacttacattacggaagggaggaaataataaatta
attaaaatatttcaccgagatggaaaatatgggttttctgatccattaacgttcaattct
gtggttgagctaataaaccactaccgaaatgagtctttagcccagtataatccaaaactt
gatgttaaattgctttacccagtatccaaatatcaacaggatcaagtggttaaagaggat
agtattgaagcagtgggaaagaaattacatgaatataacatccagttccaagagaagaat
agagagtatgacaggctgtatgaagactacacaagaacatctcaggaaattcagatgaaa
agaactgccattgaggcatttaatgaaaccataaaaatatttgaagagcagtgccaaaca
caggaaagatacagcaaagaatacatagaaaaatttaaacgggaggggaacgagaaagaa
atacaaagaattatgcacaactatgaaaagctgaaatctcgaatcagtgaaatcgtggat
agccggcgtagactggaagaagatttaaagaagcaagctgctgaatatagagagattgat
aaacgcatgaacagcattaaaccagaccttatacaactccgaaagacaagggatcagtac
ttgatgtggttgactcagaagggtgttcggcaaaagaaattgaacgaatggcttgggaat
gaaaatacggaagatcaatactctatggtggaagatgatgaggatttgccccatcaagat
gagcgaacgtggaatgtaggaaatatcaatagaagccaagctgaaaatctactacgtggc
aaacgggatggaacattccttgttcgggagagcagcaaacagggctgctatgcctgctct
gttgtagtggatggtgaagtgaagcactgtgtcatcaacaaaacacctactgggtatgga
tttgcagagccatataatttgtacaacacactgagagaactggtgctacattatcaacac
acgtcgcttgttcagcacaatgactctctcaacgtcacactagcctatccagtatatgca
caacagaggcgatga

  All links  
Gene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (5)   
   UniProt (1)   
   RefSeq(pep) (4)   
DNA sequence (4)   
   RefSeq(nuc) (4)   
Protein domain (15)   
   Pfam (15)   
All databases (26)   

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