KEGG   Gambusia affinis (western mosquitofish): 122838005
Entry
122838005         CDS       T07758                                 
Symbol
pdgfra
Name
(RefSeq) platelet-derived growth factor receptor alpha
  KO
K04363  platelet-derived growth factor receptor alpha [EC:2.7.10.1]
Organism
gaf  Gambusia affinis (western mosquitofish)
Pathway
gaf04010  MAPK signaling pathway
gaf04020  Calcium signaling pathway
gaf04144  Endocytosis
gaf04510  Focal adhesion
gaf04518  Integrin signaling
gaf04519  Cadherin signaling
gaf04540  Gap junction
gaf04810  Regulation of actin cytoskeleton
Brite
KEGG Orthology (KO) [BR:gaf00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    122838005 (pdgfra)
   04020 Calcium signaling pathway
    122838005 (pdgfra)
  09133 Signaling molecules and interaction
   04518 Integrin signaling
    122838005 (pdgfra)
   04519 Cadherin signaling
    122838005 (pdgfra)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    122838005 (pdgfra)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    122838005 (pdgfra)
   04540 Gap junction
    122838005 (pdgfra)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    122838005 (pdgfra)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:gaf01001]
    122838005 (pdgfra)
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:gaf04090]
    122838005 (pdgfra)
Enzymes [BR:gaf01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     122838005 (pdgfra)
Protein kinases [BR:gaf01001]
 Receptor tyrosine kinases (RTK)
  PDGFR family [OT]
   122838005 (pdgfra)
CD molecules [BR:gaf04090]
 Proteins
  122838005 (pdgfra)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr VEGFR1-3_N_Ig-like Ig_PDGFR_d4 Pkinase Ig_3 I-set ig Ig_2 VEGFR-1-like_Ig-like V-set C2-set_2 Ig_VEGFR-1-like_5th Ig_MYOM1
Other DBs
NCBI-GeneID: 122838005
NCBI-ProteinID: XP_043984195
Position
LG10:6863467..6887157
AA seq 1457 aa
MDSVRMYLVCGVAIVLMVSVTPGLSAPRIWPAEKELELEPHSIINISCTGQSEVVWEEPL
ADDAIVTSNGFTSALLIYNVTVEHTGYYGCRHKDKEGDENDLVEIYVLVKDPQVVFVPER
AEDLLVPYEVNLIIPCRVTAKTHNVELIRVPGGEKLHSYYDYRLGFLGDLSPGQYRCEAT
FNGQTFQSDVYTVMSLGSTELSDFEVEVKASAETVRVGEPFNVSCIGPFGPAFHQQWIHL
KTQAVNAIQTTESLPDWVIYTLSIPRAAPQDGGSYECSVRHEASGKTRVSSVAVSVFGGN
SFVTLDHRGILQTESVGILAETQYTIYINAYPAPKVSWMKDGQALSENYYISSKTSHMEG
NRYQSIVTFRQPMEKDSGNYTITAISGSRTAQFSFILQVTGSTRLNIRPSFPPILLPDED
EIVVPLHEPFTLTCRGGAKLMWETPYDMPEQSQEDNSGLFVTTIAVDEAIAMHTGYYVCL
YSDHTAEETKASSIYVYVSDPESPFVPNFFNHVPVDQSEIEIPCRVSDPSAVVTLVNVDT
NQTVPSDYDSKKGALGIFPTGTYVCKAIINGEEHISEQYIIHDSIDVLHVELSARRTALL
VGDTISVNCLAQGPYLLEDNWKYPGKPANRGTKTVRENKNEGQILYTLTIPQASTKDSGI
YSCSITAVASRDTQTKEIAIRVFAGEFLSIKPEFRDHESAELDDVREFIATISSFPDAHV
TWLKDGVPLSDLTAEISTSLKQTSETSYRSILTLIRVREEDSGNYTLRVENGNQSHEVSL
NLVVKVPAVIVDLMDIHHGSATGQSAVCITRGQPTPVVEWFICKNIKQCANDSSFWAPLP
TNSTEITMESHFDEESNLESQVMFGHLKSTLAVRCLAKNELGAVSREIKLVSNGPHPELT
VAAAVLVLLVIVIISLIVLVVIWKQKPRYEIRWRVIESVSPDGHEYIYVDPMQLPYDSRW
EFPRDRLVLGRILGSGAFGKVVEGTAYGLSRSQPVMKVAVKMLKPTARSSEKQALMSELK
IMTHLGPHLNIVNLLGACTKSGPIYIITEYCFHGDLVNYLHKNRESFLSLSPEKNKKELD
IFGINPADENSRSYVILSFECKGDYMDMKQADNTQYVPMLEMSTTSKYSDVQGSNYDHPP
SQKDSGESDNLLSDDMSEGLTTTDLLSFTYQVAKGMEFLASKNCVHRDLAARNVLLSQGK
IVKICDFGLARDIMHDNNYVSKGSTFLPVKWMAPESIFDNLYTSLSDVWSYGILLWEIFT
LGGTPYPGMVVDSSFYNKIKSGYRMSKPEHAPQDVYEMMIKCWNTEPEKRPSFMGLSENV
ASLLPSSYKRHYEKVNHDFLKSDHPAVTRVCIETDADYVDIPYKNQGKLKDRESGFDEQR
LSSDSGYIIPLPDLDPISDDDYGKRNRHSSQTSEESAIETGSSSSTYAKREGETLEDITL
LDEMCLDCSDLVEDSFL
NT seq 4374 nt   +upstreamnt  +downstreamnt
atggatagtgtgaggatgtacctggtctgtggtgttgccattgtgttgatggtttcagtt
acacctggactgtccgcccctcgcatatggccagcagaaaaggagctggagctggagccc
cactccatcatcaacatcagctgtacgggccaatcagaagtagtctgggaagaacctctg
gcggacgacgccatcgttacttcaaacggtttcacctcagctctccttatttacaacgtg
acggtcgagcacaccggctattacgggtgtaggcataaagacaaggagggcgacgagaac
gatctggtggaaatctatgtcctagtcaaagatccccaggtcgtgtttgtcccagagaga
gcagaagacctgctcgttccctatgaggtgaatttgatcatcccatgccgagtgacagca
aagacccacaatgtggaactgatccgagtccccggcggagagaagctccacagctactac
gactacagattgggcttcttgggcgacctctcccctggccagtacagatgtgaggccaca
tttaacggccagactttccaaagtgacgtctacaccgtaatgagtttgggatccacggag
ttgagcgactttgaggttgaagtcaaagccagcgcggagacggtgcgggtcggggagccc
tttaacgtctcctgtatcggaccctttggcccagccttccaccagcagtggatccatctg
aaaacgcaggctgtaaatgcgattcagacgacggaaagtcttcctgactgggtcatctac
actttgagcatcccgcgagccgcccctcaggacggcggcagctacgaatgctcagtcagg
cacgaggccagtggaaaaaccagggtgagcagcgtggctgtgtccgtgtttgggggaaac
tcctttgtcaccctggaccacagagggattctacagacggagtctgttggcattctggca
gagactcagtacaccatctacattaatgcatacccggctccaaaagtgtcatggatgaaa
gacggccaagcgctgtcggaaaactactacatttcttccaaaactagccacatggaagga
aatcggtatcagagcatcgttacgttccggcagcctatggagaaagacagcggaaattac
acaatcacagccataagcggctcacgcaccgctcagttctcatttatcctccaagtgaca
ggttccactagacttaacatcagaccgtccttcccccctattctgctaccggatgaggat
gagattgtcgtccctctccatgagcccttcacgctgacgtgtcgcggaggtgcaaagctg
atgtgggaaacaccgtacgacatgccggagcaatcgcaggaggacaacagtggccttttc
gtcaccaccatcgctgttgacgaagccatagcgatgcacacaggttattacgtttgcctc
tacagtgaccacactgcagaggaaaccaaggccagcagtatttacgtctatgtatcagat
cccgaatctccgttcgtgccaaatttctttaaccatgtgccggttgaccaaagtgagatt
gagattccctgcagggtgtctgatcctagtgctgttgtgacactggtgaatgttgacacc
aaccaaaccgtacctagtgactatgacagtaaaaagggtgctttgggaatatttcctact
ggaacttatgtctgcaaggccatcatcaacggagaggagcacatcagcgagcaatacatc
atccatgattccatagatgtcttacacgttgagctgtctgccagaagaactgctttgctg
gttggagacacaataagtgtcaactgcctggctcaaggaccttatttactggaggataac
tggaaataccctggcaaaccggctaatcggggcaccaaaactgtacgggaaaataagaac
gaaggccagatcctgtacaccttgacaatcccacaagcctcaaccaaagacagcggcatc
tactcctgttccattaccgctgtagcgtctagagacacccagacaaaggaaatagctatt
cgagtgtttgccggtgagtttttgtccatcaagccggagtttcgagaccacgaatctgct
gagctggatgacgtccgggagttcattgccacaatttcctcctttcctgatgcccatgtt
acttggctcaaggacggcgtcccgctcagtgacctgactgctgagatctccaccagtttg
aagcagaccagcgagaccagctacagaagtattctcaccctgatccgggtcagggaggag
gacagtgggaactacaccctgcgggtggagaacggaaaccagagccatgaagtcagctta
aacctggtggttaaagtgcctgcagtcattgtggacctcatggacatccaccatggctcc
gccacaggacagtctgctgtgtgcattaccagggggcagcctactcctgttgtggagtgg
ttcatatgcaagaacatcaaacaatgcgccaatgactcgtctttttgggcgcctctaccc
accaactccacagagatcacgatggagtcccactttgatgaggagagcaacctggagagc
caggtcatgtttgggcatctgaaaagcactctggctgtgcgatgccttgccaagaatgaa
ttaggagctgtcagcagggagatcaaattggtgtccaatggccctcaccctgagctgacg
gtagctgctgctgtgctggtgctcctggtcattgtcatcatctcactcattgtcttggtt
gttatctggaagcagaaaccacggtacgagatccgctggagggtcatagagtctgtgagt
ccagacggtcacgagtacatctatgtggatcccatgcagcttccctatgactccagatgg
gagtttccccgagatagacttgtgcttggccggatcctgggctctggagccttcgggaag
gtggttgagggcactgcctacggacttagccgctctcagcctgttatgaaggtggcagtg
aaaatgctgaaacctacggctcgctccagtgagaagcaggctctgatgtctgagctgaag
atcatgactcacctcggacctcatctcaacatcgtaaacctcctgggagcgtgcaccaag
tcaggccctatctacattatcaccgagtactgcttccacggcgacctggtcaactatctg
cacaagaacagggagagcttcctcagcctgagtccagagaaaaacaagaaggagctggat
atctttgggatcaatcccgcggacgagaacagcaggagttacgtgatcttgtccttcgag
tgtaaaggagactacatggacatgaagcaggcggacaacacccagtatgtgcccatgctg
gagatgagcacaacctccaagtactctgacgtccagggatctaactacgaccaccctcct
tcacagaaagactcgggcgaatccgacaacctgctgtcagacgacatgagcgaaggcctc
acgaccaccgacctgctcagcttcacctaccaggtggccaaaggaatggagttcctggcg
tccaaaaattgcgtgcatcgagaccttgcagccaggaacgtccttctctctcaaggcaag
attgttaagatctgtgactttgggctggccagagacatcatgcatgacaacaactacgtc
tccaaaggaagcacctttttgccagtgaagtggatggctccggaaagtatttttgacaac
ctgtacaccagtcttagcgacgtttggtcatatggcatcctcctctgggaaatattcacc
ctaggtggcactccgtacccagggatggtggtggattccagcttctacaacaaaatcaag
agcggatacaggatgtcaaaacccgagcacgcgccgcaagacgtgtacgagatgatgata
aagtgctggaacacagagccggaaaagaggccttccttcatgggtctgagtgaaaatgtg
gcgtctttgctgccctccagctacaagaggcactatgagaaggtgaaccacgattttctg
aagagcgaccatcccgccgtcacccgagtctgcatcgagacggacgccgactacgtcgac
attccctacaagaaccagggcaagctaaaggacagggaaagcggcttcgacgagcagcgg
ctgagctccgacagcggctacatcatcccactccctgacctggaccctatatctgatgac
gactacggaaagaggaacaggcacagctctcaaacgtctgaggagagcgccatcgagact
ggctcaagtagctccacctacgctaagcgcgagggcgagaccctggaggacatcacgctg
ttggacgagatgtgtctggactgcagcgacctggtcgaggacagctttctgtga

  All links  
Gene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (13)   
   Pfam (13)   
All databases (17)   

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