KEGG   Gekko japonicus (Schlegel's Japanese gecko): 107110982
Entry
107110982         CDS       T04299                                 
Symbol
PIK3CA
Name
(RefSeq) phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
  KO
K00922  phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
Organism
gja  Gekko japonicus (Schlegel's Japanese gecko)
Pathway
gja00562  Inositol phosphate metabolism
gja01100  Metabolic pathways
gja04012  ErbB signaling pathway
gja04068  FoxO signaling pathway
gja04070  Phosphatidylinositol signaling system
gja04081  Hormone signaling
gja04140  Autophagy - animal
gja04145  Phagocytosis
gja04150  mTOR signaling pathway
gja04210  Apoptosis
gja04218  Cellular senescence
gja04370  VEGF signaling pathway
gja04510  Focal adhesion
gja04517  IgSF CAM signaling
gja04518  Integrin signaling
gja04620  Toll-like receptor signaling pathway
gja04625  C-type lectin receptor signaling pathway
gja04810  Regulation of actin cytoskeleton
gja04910  Insulin signaling pathway
gja04914  Progesterone-mediated oocyte maturation
gja05100  Bacterial invasion of epithelial cells
gja05132  Salmonella infection
gja05168  Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:gja00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    107110982 (PIK3CA)
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    107110982 (PIK3CA)
   04370 VEGF signaling pathway
    107110982 (PIK3CA)
   04068 FoxO signaling pathway
    107110982 (PIK3CA)
   04070 Phosphatidylinositol signaling system
    107110982 (PIK3CA)
   04150 mTOR signaling pathway
    107110982 (PIK3CA)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    107110982 (PIK3CA)
   04517 IgSF CAM signaling
    107110982 (PIK3CA)
   04518 Integrin signaling
    107110982 (PIK3CA)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagocytosis
    107110982 (PIK3CA)
   04140 Autophagy - animal
    107110982 (PIK3CA)
  09143 Cell growth and death
   04210 Apoptosis
    107110982 (PIK3CA)
   04218 Cellular senescence
    107110982 (PIK3CA)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    107110982 (PIK3CA)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    107110982 (PIK3CA)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    107110982 (PIK3CA)
   04625 C-type lectin receptor signaling pathway
    107110982 (PIK3CA)
  09152 Endocrine system
   04910 Insulin signaling pathway
    107110982 (PIK3CA)
   04914 Progesterone-mediated oocyte maturation
    107110982 (PIK3CA)
 09160 Human Diseases
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    107110982 (PIK3CA)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    107110982 (PIK3CA)
   05100 Bacterial invasion of epithelial cells
    107110982 (PIK3CA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:gja04131]
    107110982 (PIK3CA)
Enzymes [BR:gja01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.153  phosphatidylinositol-4,5-bisphosphate 3-kinase
     107110982 (PIK3CA)
Membrane trafficking [BR:gja04131]
 Endocytosis
  Rab GTPases and associated proteins
   Rab associated proteins
    107110982 (PIK3CA)
SSDB
Motif
Pfam: PI3Ka PI3_PI4_kinase PI3K_rbd PI3K_C2 PI3K_p85B DUF2321 ABC1 Ribosomal_S15 Retrotran_gag_4
Other DBs
NCBI-GeneID: 107110982
NCBI-ProteinID: XP_015267337
UniProt: A0ABM1K0V0
Position
Un
AA seq 1068 aa
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLNIKHELFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVCPPNIESSPDLPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKHPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
NFTMPSYSRRISTATPYMNGEASAKSLWVINSNLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLQYEMHILDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SSPVKFPDMSVIEEHANWTISRELGYNYSPAGQSSRIARDNELSESDKEQLRAICTRDPL
SEITEQEKDFLWRHRHYCVNMPEILPKLLLSVKWNSRDEVTQMYCLIKDWPPIKPEQAME
LLDCNYPDRMVRAFAVRCLEKFLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKNVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGTLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHALHQWLKDKNKGEMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
NT seq 3207 nt   +upstreamnt  +downstreamnt
atgcctccaagaccatcatctggtgaactgtggggcatccacttgatgccccctagaatc
cttgtggaatgtcttctacctaatggtatgatagtgactttagaatgcctccgtgaggcc
acattgttaaatattaaacacgaactctttaaagaagctaggaaataccctctctaccat
ctccttcaagaggagtcatcttacattttcgtaagtgttacccaagaagcagaaagagaa
gaatttttcgatgaaacccggagattatgtgacctgcggctttttcaaccttttctaaaa
gtcatagaaccagtaggcaacagagaagagaaaattctgaatcgtgaaattggttttgct
attggcatgcctatctgtgaatttgacttggttaaagatccagaagttcaggacttcaga
agaaacattctgaatgtctgtaaagaagctgtagatcttcgagatgctaatgcgccccat
agcagagcactatatgtctgtccccccaacatagaatcatcgcctgatttgcccaagcat
atatacaataaattagataaagggcaaataatagtggtcatctgggtaatagtctctccc
aataatgacaagcagaaatacaccttaaaaatcaatcatgactatgtgccagagcaagta
atcgcagaagcaatcaggaaaaaaacacggagtatgttactgtcatcggagcagctaaag
ctatgcgttttggagtatcagggaaagtatattttaaaagtgtgtggttgtgatgaatac
ttgctagaaaaacatcccctgagtcagtataagtacatccgaagttgtatcatgcttggt
cgaatgcccaacctcatgctgatggcaaaggaaagcctttacacccagctgccattggat
aacttcacaatgccatcttattccaggcgtatctctacagctacgccatacatgaatggt
gaagcttcagccaaatctctctgggttattaacagtaatctcagaataagaattctctgt
gccacctacgtaaatgtaaatattcgagatattgacaagatctatgtccgaactggtatc
tatcatggaggagaaccattgtgtgataatgtgaatactcagagagtaccttgctccaat
cccagatggaatgaatggctgcagtatgagatgcatatccttgatctcccacgtgctgcc
cggctttgcctttctatctgctcagttaaaggtagaaagggtgcgaaggaggagcactgc
ccattggcgtgggggaacattaacatgtttgattacacagacactcttgtttctggcaaa
atggctctgaatctgtggcccgtacctcatggtctggaagacctgctcaatcccattgga
gttactggatcaaacccaaataaggaaactccatgtttagagctggaatttgattggttt
agcagtcctgtaaagtttcccgacatgtcagtgattgaagaacatgccaattggactatc
tctcgagaactagggtataactacagtcctgctgggcagagcagtagaatagctagagac
aacgaactgagtgaaagtgacaaagagcagctccgtgcaatttgcactcgagatcccctg
tctgaaataactgaacaagagaaggacttcctctggaggcacaggcattattgtgtaaat
atgccagaaattctacccaagctgcttttgtctgttaagtggaactccagagatgaagta
acccagatgtactgcttgatcaaagactggcctcccatcaaacctgagcaggcgatggaa
cttctggactgcaactaccccgatcggatggtgcgtgcttttgcagtgcggtgtctggaa
aaattcttgacagatgataagctgtctcagtatttgattcaactggtgcaggttctaaaa
tatgagcaatacttggataatctgttagtgaggtttttactgaagaaggcgctgaccaat
caaagaataggacatttcttcttttggcatctcaagtctgaaatgcacaacaaaaatgtg
agccagaggtttggtctgcttttggaatcctattgccgagcatgtgggatgtacctaaaa
catctgagcaggcaggtagaagctatggaaaaactgattaacctcacagacatcctcaag
caagagaaaaaggatgaaacgcaaaaggtacagatgaagttccttgtggagcaaatgagg
cggccagacttcatggatgcattgcaaggctttatatctcctctcaatcctgctcatcag
cttggaacccttaggcttgaggagtgcagaattatgtcgtctgcaaaaaggccattgtgg
ctcaattgggaaaacccagatattatgtctgagctgctgtttcagaacaatgagatcatc
ttcaaaaacggggatgatctgcgccaagatatgctgacgcttcagatcatccgaattatg
gaaaatatctggcaaaatcaaggtcttgatcttaggatgcttccttatggttgtttatcg
attggtgactgtgtggggctcatcgaagttgtgaggaattcgcacacaatcatgcaaatt
caatgcaagggtggccttaaaggtgcgctgcagttcaacagtcatgcgttacaccagtgg
ctcaaagacaagaacaaaggggaaatgtatgatgcagctattgatttgtttacacgctct
tgtgctggctattgcgtggcgaccttcatactgggaattggcgatcgtcacaatagcaat
atcatggtgaaagatgatgggcagctgttccacattgattttggacatttcttggatcac
aagaagaagaagtttggatacaaacgtgagcgggtgccctttgtcttaacgcaagatttc
ttgatagtgattagcaaaggagcccaagaatgtaccaaaacaaaggaatttgaaaggttt
caagaaatgtgttacaaagcttacttagccatccggcagcatgccaacctcttcataaac
ctcttctccatgatgctcggttcgggaatgccagagctgcagtcttttgacgacattgca
tatattcggaagacactggcattggacaaaactgagcaggaagcacttgagtatttcatg
aagcagatgaacgatgctcatcatggcggctggacgacaaaaatggactggatcttccat
acaatcaagcaacacgctttgaactga

  All links  
Gene (14)   
   RefGene (11)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (9)   
   Pfam (9)   
All databases (27)   

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