KEGG   Leopardus geoffroyi (Geoffroy's cat): 123589468
Entry
123589468         CDS       T10761                                 
Symbol
PRKCB
Name
(RefSeq) protein kinase C beta type isoform X1
  KO
K19662  classical protein kinase C beta type [EC:2.7.11.13]
Organism
lgf  Leopardus geoffroyi (Geoffroy's cat)
Pathway
lgf01521  EGFR tyrosine kinase inhibitor resistance
lgf04010  MAPK signaling pathway
lgf04012  ErbB signaling pathway
lgf04014  Ras signaling pathway
lgf04015  Rap1 signaling pathway
lgf04020  Calcium signaling pathway
lgf04062  Chemokine signaling pathway
lgf04064  NF-kappa B signaling pathway
lgf04066  HIF-1 signaling pathway
lgf04070  Phosphatidylinositol signaling system
lgf04071  Sphingolipid signaling pathway
lgf04082  Neuroactive ligand signaling
lgf04150  mTOR signaling pathway
lgf04270  Vascular smooth muscle contraction
lgf04310  Wnt signaling pathway
lgf04370  VEGF signaling pathway
lgf04510  Focal adhesion
lgf04517  IgSF CAM signaling
lgf04540  Gap junction
lgf04613  Neutrophil extracellular trap formation
lgf04650  Natural killer cell mediated cytotoxicity
lgf04662  B cell receptor signaling pathway
lgf04666  Fc gamma R-mediated phagosome formation
lgf04670  Leukocyte transendothelial migration
lgf04713  Circadian entrainment
lgf04720  Long-term potentiation
lgf04723  Retrograde endocannabinoid signaling
lgf04724  Glutamatergic synapse
lgf04725  Cholinergic synapse
lgf04726  Serotonergic synapse
lgf04727  GABAergic synapse
lgf04728  Dopaminergic synapse
lgf04730  Long-term depression
lgf04750  Inflammatory mediator regulation of TRP channels
lgf04911  Insulin secretion
lgf04912  GnRH signaling pathway
lgf04916  Melanogenesis
lgf04918  Thyroid hormone synthesis
lgf04919  Thyroid hormone signaling pathway
lgf04921  Oxytocin signaling pathway
lgf04925  Aldosterone synthesis and secretion
lgf04928  Parathyroid hormone synthesis, secretion and action
lgf04929  GnRH secretion
lgf04931  Insulin resistance
lgf04933  AGE-RAGE signaling pathway in diabetic complications
lgf04935  Growth hormone synthesis, secretion and action
lgf04960  Aldosterone-regulated sodium reabsorption
lgf04961  Endocrine and other factor-regulated calcium reabsorption
lgf04970  Salivary secretion
lgf04971  Gastric acid secretion
lgf04972  Pancreatic secretion
lgf04973  Carbohydrate digestion and absorption
lgf05017  Spinocerebellar ataxia
lgf05022  Pathways of neurodegeneration - multiple diseases
lgf05031  Amphetamine addiction
lgf05032  Morphine addiction
lgf05140  Leishmaniasis
lgf05143  African trypanosomiasis
lgf05146  Amoebiasis
lgf05161  Hepatitis B
lgf05163  Human cytomegalovirus infection
lgf05164  Influenza A
lgf05170  Human immunodeficiency virus 1 infection
lgf05171  Coronavirus disease
lgf05200  Pathways in cancer
lgf05205  Proteoglycans in cancer
lgf05206  MicroRNAs in cancer
lgf05207  Chemical carcinogenesis - receptor activation
lgf05214  Glioma
lgf05223  Non-small cell lung cancer
lgf05225  Hepatocellular carcinoma
lgf05231  Choline metabolism in cancer
lgf05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:lgf00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    123589468 (PRKCB)
   04012 ErbB signaling pathway
    123589468 (PRKCB)
   04014 Ras signaling pathway
    123589468 (PRKCB)
   04015 Rap1 signaling pathway
    123589468 (PRKCB)
   04310 Wnt signaling pathway
    123589468 (PRKCB)
   04370 VEGF signaling pathway
    123589468 (PRKCB)
   04064 NF-kappa B signaling pathway
    123589468 (PRKCB)
   04066 HIF-1 signaling pathway
    123589468 (PRKCB)
   04020 Calcium signaling pathway
    123589468 (PRKCB)
   04070 Phosphatidylinositol signaling system
    123589468 (PRKCB)
   04071 Sphingolipid signaling pathway
    123589468 (PRKCB)
   04150 mTOR signaling pathway
    123589468 (PRKCB)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    123589468 (PRKCB)
   04517 IgSF CAM signaling
    123589468 (PRKCB)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    123589468 (PRKCB)
   04540 Gap junction
    123589468 (PRKCB)
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    123589468 (PRKCB)
   04650 Natural killer cell mediated cytotoxicity
    123589468 (PRKCB)
   04662 B cell receptor signaling pathway
    123589468 (PRKCB)
   04666 Fc gamma R-mediated phagosome formation
    123589468 (PRKCB)
   04670 Leukocyte transendothelial migration
    123589468 (PRKCB)
   04062 Chemokine signaling pathway
    123589468 (PRKCB)
  09152 Endocrine system
   04911 Insulin secretion
    123589468 (PRKCB)
   04929 GnRH secretion
    123589468 (PRKCB)
   04912 GnRH signaling pathway
    123589468 (PRKCB)
   04921 Oxytocin signaling pathway
    123589468 (PRKCB)
   04935 Growth hormone synthesis, secretion and action
    123589468 (PRKCB)
   04918 Thyroid hormone synthesis
    123589468 (PRKCB)
   04919 Thyroid hormone signaling pathway
    123589468 (PRKCB)
   04928 Parathyroid hormone synthesis, secretion and action
    123589468 (PRKCB)
   04916 Melanogenesis
    123589468 (PRKCB)
   04925 Aldosterone synthesis and secretion
    123589468 (PRKCB)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    123589468 (PRKCB)
  09154 Digestive system
   04970 Salivary secretion
    123589468 (PRKCB)
   04971 Gastric acid secretion
    123589468 (PRKCB)
   04972 Pancreatic secretion
    123589468 (PRKCB)
   04973 Carbohydrate digestion and absorption
    123589468 (PRKCB)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    123589468 (PRKCB)
   04961 Endocrine and other factor-regulated calcium reabsorption
    123589468 (PRKCB)
  09156 Nervous system
   04724 Glutamatergic synapse
    123589468 (PRKCB)
   04727 GABAergic synapse
    123589468 (PRKCB)
   04725 Cholinergic synapse
    123589468 (PRKCB)
   04728 Dopaminergic synapse
    123589468 (PRKCB)
   04726 Serotonergic synapse
    123589468 (PRKCB)
   04720 Long-term potentiation
    123589468 (PRKCB)
   04730 Long-term depression
    123589468 (PRKCB)
   04723 Retrograde endocannabinoid signaling
    123589468 (PRKCB)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    123589468 (PRKCB)
  09159 Environmental adaptation
   04713 Circadian entrainment
    123589468 (PRKCB)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    123589468 (PRKCB)
   05206 MicroRNAs in cancer
    123589468 (PRKCB)
   05205 Proteoglycans in cancer
    123589468 (PRKCB)
   05207 Chemical carcinogenesis - receptor activation
    123589468 (PRKCB)
   05231 Choline metabolism in cancer
    123589468 (PRKCB)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    123589468 (PRKCB)
   05214 Glioma
    123589468 (PRKCB)
   05223 Non-small cell lung cancer
    123589468 (PRKCB)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    123589468 (PRKCB)
   05161 Hepatitis B
    123589468 (PRKCB)
   05171 Coronavirus disease
    123589468 (PRKCB)
   05164 Influenza A
    123589468 (PRKCB)
   05163 Human cytomegalovirus infection
    123589468 (PRKCB)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    123589468 (PRKCB)
   05140 Leishmaniasis
    123589468 (PRKCB)
   05143 African trypanosomiasis
    123589468 (PRKCB)
  09164 Neurodegenerative disease
   05017 Spinocerebellar ataxia
    123589468 (PRKCB)
   05022 Pathways of neurodegeneration - multiple diseases
    123589468 (PRKCB)
  09165 Substance dependence
   05031 Amphetamine addiction
    123589468 (PRKCB)
   05032 Morphine addiction
    123589468 (PRKCB)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    123589468 (PRKCB)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    123589468 (PRKCB)
   04933 AGE-RAGE signaling pathway in diabetic complications
    123589468 (PRKCB)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    123589468 (PRKCB)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:lgf01001]
    123589468 (PRKCB)
Enzymes [BR:lgf01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.13  protein kinase C
     123589468 (PRKCB)
Protein kinases [BR:lgf01001]
 Serine/threonine kinases: AGC group
  PKC family [OT]
   123589468 (PRKCB)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr C1_1 C2 Pkinase_C Kinase-like ABC1 CEP76-C2
Other DBs
NCBI-GeneID: 123589468
NCBI-ProteinID: XP_045317539
Position
E3:complement(22709384..23042758)
AA seq 673 aa
MADPAAGPPPSEGEESTVRFARKGALRQKNVHEVKNHKFTARFFKQPTFCSHCTDFIWGF
GKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPASDDPRSKHKFKIHTYSSPTFCDHCGS
LLYGLIHQGMKCDTCMMNVHKRCVMNVPSLCGTDHTERRGRIYIQAHIEREVLIVVVRDA
KNLVPMDPNGLSDPYVKLKLIPDPKSESKQKTKTIKCSLNPEWNETFRFQLKESDKDRRL
SVEIWDWDLTSRNDFMGSLSFGISELQKAGVDGWFKLLSQEEGEYFNVPVPPEGSEGNEE
LRQKFERAKIGQGTKAPEEKTTNTISKLDNNGNRDRMKLTDFNFLMVLGKGSFGKVMLSE
RKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPGKPPFLTQLHSCFQTMDRLYFVM
EYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHI
KIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAP
FEGEDEDELFQSIMEHNVAYPKSMSKEAVAICKGLMTKHPGKRLGCGPEGERDIKEHAFF
RYIDWEKLERKEIQPPYKPKACGRNAENFDRFFTRHPPVLTPPDQEVIRNIDQSEFEGFS
FVNSEFLKPEVKS
NT seq 2022 nt   +upstreamnt  +downstreamnt
atggctgacccggctgcggggccgccgccgagcgagggcgaggagagcaccgtgcgcttc
gcccgcaaaggcgccctccggcagaaaaacgtgcacgaggtgaagaaccacaaattcacc
gcccgcttcttcaagcagcccaccttctgcagccactgcaccgacttcatctggggcttc
gggaagcaaggattccagtgccaagtctgctgtttcgtcgtgcacaagcggtgccatgaa
tttgtcactttctcctgcccaggcgctgacaaaggtccagcctctgatgacccccggagc
aagcacaagtttaagatccacacatactccagccccacgttttgtgaccactgcgggtca
ctgctgtatggactcatccaccaggggatgaaatgtgacacctgcatgatgaacgtgcac
aagcgttgcgtgatgaacgtccccagcctgtgcggcacagaccacaccgagcgccgaggc
cgcatctacatccaggcgcacatcgagagggaagtcctcatcgtcgtcgtaagagatgct
aaaaaccttgtacctatggaccccaatggcttgtcagacccttatgtgaaactgaaactg
attcctgaccccaagagcgagagcaagcagaagaccaaaaccatcaaatgctccctcaac
cccgagtggaatgagacattcagattccaactgaaagaatcggacaaagacagaaggctg
tctgtagagatttgggattgggatctgaccagcaggaacgacttcatgggatctttgtcg
tttgggatttccgaactgcagaaagccggtgttgatggctggtttaagctgctgagccag
gaggaaggcgagtacttcaatgtgcctgtgccgccagagggaagtgaagggaatgaagaa
ctacggcagaaattcgagagggccaagatcggtcaggggaccaaggctccagaagaaaag
acgaccaacaccatatccaaacttgacaacaatgggaacagagaccgaatgaaactgacc
gattttaacttcctgatggtgctcgggaaaggaagctttggcaaggtcatgctctcagag
cggaaaggcacagacgagctctatgccgtgaagatcctgaagaaggacgtcgtgatccaa
gatgacgatgtggaatgcacgatggtggagaagcgggtgctggccctgcccgggaagccg
ccgttcctgacccagctccattcctgcttccagaccatggaccgcctgtactttgtgatg
gagtacgtgaacgggggtgacctcatgtaccacatccaacaagttggccggtttaaggag
cctcatgctgtattttacgctgcagaaattgccatcggtctgttcttcttacagagcaag
ggcatcatttaccgtgacctcaaacttgacaatgtgatgctggattcagagggccacatc
aagattgctgattttggcatgtgtaaggaaaacatctgggatggggtgaccaccaagaca
ttctgtggcactccagactacatcgcccctgagataattgcttatcagccctatgggaag
tccgtggattggtgggcatttggagtcctgctgtatgaaatgttagctggccaggcaccc
tttgaaggggaggatgaggacgagctcttccagtccatcatggaacacaacgtggcttac
ccaaagtccatgtccaaggaagctgtggccatctgcaaagggctgatgaccaaacacccg
ggcaaacgtctgggttgtggacctgaaggtgaacgtgacatcaaagagcatgcatttttc
cggtatattgattgggagaaacttgaacgcaaagagatccagcccccgtataagccaaaa
gcctgtgggcgaaatgctgaaaacttcgaccggtttttcacccgccatccacccgtccta
acacctcccgaccaggaagtcatcaggaatattgaccaatcagaattcgaaggattttcc
tttgttaactctgaatttttaaaacctgaagtcaagagctaa

  All links  
Gene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (3)   
   RefSeq(pep) (3)   
DNA sequence (3)   
   RefSeq(nuc) (3)   
Protein domain (8)   
   Pfam (8)   
All databases (16)   

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