KEGG   Labrus mixtus (cuckoo wrasse): 132978836
Entry
132978836         CDS       T10666                                 
Name
(RefSeq) phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
  KO
K00922  phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
Organism
lmix  Labrus mixtus (cuckoo wrasse)
Pathway
lmix00562  Inositol phosphate metabolism
lmix01100  Metabolic pathways
lmix04012  ErbB signaling pathway
lmix04068  FoxO signaling pathway
lmix04070  Phosphatidylinositol signaling system
lmix04081  Hormone signaling
lmix04140  Autophagy - animal
lmix04145  Phagocytosis
lmix04150  mTOR signaling pathway
lmix04210  Apoptosis
lmix04218  Cellular senescence
lmix04370  VEGF signaling pathway
lmix04510  Focal adhesion
lmix04517  IgSF CAM signaling
lmix04518  Integrin signaling
lmix04620  Toll-like receptor signaling pathway
lmix04625  C-type lectin receptor signaling pathway
lmix04810  Regulation of actin cytoskeleton
lmix04910  Insulin signaling pathway
lmix04914  Progesterone-mediated oocyte maturation
lmix05100  Bacterial invasion of epithelial cells
lmix05132  Salmonella infection
lmix05168  Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:lmix00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    132978836
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    132978836
   04370 VEGF signaling pathway
    132978836
   04068 FoxO signaling pathway
    132978836
   04070 Phosphatidylinositol signaling system
    132978836
   04150 mTOR signaling pathway
    132978836
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    132978836
   04517 IgSF CAM signaling
    132978836
   04518 Integrin signaling
    132978836
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagocytosis
    132978836
   04140 Autophagy - animal
    132978836
  09143 Cell growth and death
   04210 Apoptosis
    132978836
   04218 Cellular senescence
    132978836
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    132978836
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    132978836
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    132978836
   04625 C-type lectin receptor signaling pathway
    132978836
  09152 Endocrine system
   04910 Insulin signaling pathway
    132978836
   04914 Progesterone-mediated oocyte maturation
    132978836
 09160 Human Diseases
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    132978836
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    132978836
   05100 Bacterial invasion of epithelial cells
    132978836
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:lmix04131]
    132978836
Enzymes [BR:lmix01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.153  phosphatidylinositol-4,5-bisphosphate 3-kinase
     132978836
Membrane trafficking [BR:lmix04131]
 Endocytosis
  Rab GTPases and associated proteins
   Rab associated proteins
    132978836
SSDB
Motif
Pfam: PI3Ka PI3_PI4_kinase PI3K_C2 PI3K_rbd PI3K_p85B DUF2321 ABC1 Colicin-DNase Ribosomal_S15
Other DBs
NCBI-GeneID: 132978836
NCBI-ProteinID: XP_060900147
Position
8:9973584..9988283
AA seq 1068 aa
MPPRPSSGELWGMHLMPPSILVDCLLPNGMILTLECLREATLITVKHELFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILNREIGFA
IGMPICEFDLVKDPEVQDFRRNILNVCKEAVDLRDSNGPHSRALYVYPPNVESSVELPRH
IYNKLDKGQIIVVIWVIVSPSNDKQKYTLKINHDYVPEQVIAEAIRKKTRSMLLSQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMAKDSLYSQLPMD
NFTMPSYARRISTATPYMNGETATKSLWTINGTLRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTQRVPCSNPRWNEWLNYDMYIPDIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDHF
SCPVKYPDMTIIEDHANWNISRELGFNYCHTGLSNRLARDNPLTDTDNEQLRLVCNRDPL
SEITEQEKDFLWRHRQDCVNMPEILPKILLAVKWNSRDEIAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMIREFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMRRPDYMDALQNFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
NT seq 3207 nt   +upstreamnt  +downstreamnt
atgcctcccaggccctcctcaggagaactatgggggatgcacttgatgccccctagcatc
ctagtggactgccttctgccaaatggcatgattctcacgttggagtgcctccgggaggcc
acactgatcacagtcaagcatgagcttttcaaagaggccaggaagtaccctctataccat
ctgctgcaggaggagagctcctacatctttgtcagtgtcacacaagaggcagagcgagag
gagttttatgatgagaccaggaggttgtgcgatctcaggctctttcaggcttttcttaaa
gtaatcgagccagtaggcaacagagaagagaagatcctcaacagagagataggttttgcg
attggaatgcccatttgtgagtttgatttggtgaaagacccagaagtgcaggacttcaga
aggaacattttaaatgtatgtaaagaggctgtggacctccgagacagtaacggaccccac
agtagagctttgtacgtgtatcctcccaatgtagaatcctctgttgaacttccccggcac
atctataacaagctggacaaaggtcaaatcatagtggtcatatgggttattgtgtcaccc
agcaatgacaagcagaagtacaccctgaagatcaaccacgactatgtaccggagcaggtg
atagccgaagccattcgtaaaaagacgcgcagcatgctgctctcccaggagcagctaaag
atgtgtgtgcaggagtatcagggaaagtacatcctcaaagtatgcggctgtgacgagtac
ttactggagaaataccctctgagtcagtacaagtatgtgcgcagctgtatcatgctggga
cggatgcccaacttgatgctaatggccaaagacagcctgtattcccagctgccgatggac
aacttcaccatgccgtcttatgcaaggcgaatatccacagcaacgccctacatgaacggc
gaaacagccacaaagtctttgtggactatcaacggaacactgaggatcaggatactgtgc
gctacttacgtcaatgtcaacatcagagatattgacaagatctacgtcaggactgggata
taccacggtggagagcagttgtgtgacaacgtcaacacccagcgcgtgccctgctctaat
ccaaggtggaacgagtggctgaactacgacatgtacattccagacatcccacgagccgcc
cggctctgcctctccatctgctcggtgaaaggaaggaagggagctaaagaggagcactgt
cccctcgcctggggcaacatcaacctgtttgactacacccacacactggttgcagggaag
atggctctcaatctatggcctgttccacacggtctggaggacctgctcaaccctatcggc
gtcacaggatctaatccaaacaaggaaaccccttgtctggagctggagtttgatcatttc
agttgccccgtcaagtaccctgatatgaccatcatcgaagatcatgctaactggaatatc
tccagagagcttggctttaattactgccacaccggtttgagtaacagactggcgcgtgac
aaccccctgaccgacaccgacaatgagcagctacgtctggtgtgcaacagggacccgctt
tctgaaataactgagcaggagaaagactttctatggaggcacagacaagactgtgtcaac
atgccagagatccttcccaagatcctcctggctgtgaaatggaactcccgagatgagatc
gcacagatgtattgccttctgaaggactggcctgctatcaagccagaacaagccatggag
ttgctggattgcaacttccctgatcctatgatccgagagtttgccgtaaagtgccttgag
aaatacctaactgatgacaaactctcacagtacctcattcaactggttcaggttcttaag
tatgagcagtaccttgataacccacttgcacgcttcctgctgaaaaaggctttaaccaat
cagaggataggacatttcttcttctggcatttaaagtcagagatgcacaacaagacagtg
agccagcggtttggcctgctgctggagtcgtactgccgggcctgtggcatgtatctgaag
cacctgagcagacaggtggaggccatggagaaactcatcaatctgaccgacctcctcaaa
caggagaaaaaagatgaggcacagaaggttcaaatgaagtttctggtggagcagatgaga
cggcctgattatatggacgccctgcagaacttcacctccccgctgaatccagctcatcag
ctcggaaacctccgcctggaagaatgcaggatgatgtcgtcagccaagcgaccgctgtgg
cttaattgggaaaacccagatatgatgtcagagctgctctttcaaaacaacgaaatcatc
ttcaaaaatggagatgatctgaggcaggacatgctgacgctgcagatcattaggataatg
gagaacatctggcagaaccaaggccttgatctcaggatgttgccttatggctgtctgtcc
atcggagactgtgtgggcttgatcgaagtggtgaggaactctcacaccatcatgcagatc
cagtgcaaaggaggcctgaagggggcgctgcagttcaacagccacacgctgcatcagtgg
ctcaaggataagaacaagggggagatgtatgaccaggccatcgatctgttcacccggtcc
tgtgctggttactgtgtagccacatttatcctgggcataggcgacagacacaacagcaac
attatggtcaaagacgatggacagctgtttcacatagactttggacactttctcgaccac
aagaagaaaaagtttgggtacaagagagaacgggtgcccttcgtgctcacgcaggatttc
ctgattgtaattagcaaaggaactcaggaatgcactaaaacaagggagtttgaaaggttc
caggagatgtgttacaaagcctatcttgcaatccggcagcacgccaacctcttcattaac
ctcttctccatgatgctgggctcggggatgcccgagctgcagtcgttcgacgacatcgct
tacatcaggaagaccctggccttggacaagacggagcaggaggccttggactacttcatg
aagcagatgaacgacgctcaccacggcggctggactacaaagatggactggatcttccac
acaatccggcagcacgccatgaactaa

  All links  
Gene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (9)   
   Pfam (9)   
All databases (14)   

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