KEGG   Oryzias latipes (Japanese medaka): 101168152
Entry
101168152         CDS       T02443                                 
Name
(RefSeq) phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
  KO
K00922  phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
Organism
ola  Oryzias latipes (Japanese medaka)
Pathway
ola00562  Inositol phosphate metabolism
ola01100  Metabolic pathways
ola04012  ErbB signaling pathway
ola04068  FoxO signaling pathway
ola04070  Phosphatidylinositol signaling system
ola04081  Hormone signaling
ola04140  Autophagy - animal
ola04145  Phagocytosis
ola04150  mTOR signaling pathway
ola04210  Apoptosis
ola04218  Cellular senescence
ola04370  VEGF signaling pathway
ola04510  Focal adhesion
ola04517  IgSF CAM signaling
ola04518  Integrin signaling
ola04620  Toll-like receptor signaling pathway
ola04625  C-type lectin receptor signaling pathway
ola04810  Regulation of actin cytoskeleton
ola04910  Insulin signaling pathway
ola04914  Progesterone-mediated oocyte maturation
ola05100  Bacterial invasion of epithelial cells
ola05132  Salmonella infection
ola05168  Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:ola00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    101168152
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    101168152
   04370 VEGF signaling pathway
    101168152
   04068 FoxO signaling pathway
    101168152
   04070 Phosphatidylinositol signaling system
    101168152
   04150 mTOR signaling pathway
    101168152
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    101168152
   04517 IgSF CAM signaling
    101168152
   04518 Integrin signaling
    101168152
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagocytosis
    101168152
   04140 Autophagy - animal
    101168152
  09143 Cell growth and death
   04210 Apoptosis
    101168152
   04218 Cellular senescence
    101168152
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    101168152
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    101168152
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    101168152
   04625 C-type lectin receptor signaling pathway
    101168152
  09152 Endocrine system
   04910 Insulin signaling pathway
    101168152
   04914 Progesterone-mediated oocyte maturation
    101168152
 09160 Human Diseases
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    101168152
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    101168152
   05100 Bacterial invasion of epithelial cells
    101168152
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:ola04131]
    101168152
Enzymes [BR:ola01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.153  phosphatidylinositol-4,5-bisphosphate 3-kinase
     101168152
Membrane trafficking [BR:ola04131]
 Endocytosis
  Rab GTPases and associated proteins
   Rab associated proteins
    101168152
SSDB
Motif
Pfam: PI3Ka PI3_PI4_kinase PI3K_rbd PI3K_C2 PI3K_p85B ABC1 DUF2321 Ribosomal_S15 Lipoprotein_Ltp
Other DBs
NCBI-GeneID: 101168152
NCBI-ProteinID: XP_004078950
UniProt: H2LYJ4
Position
17:14461477..14483413
AA seq 1068 aa
MPPRPSSGELWGMHLMPPSIVVDCLLPNGMILSLECLREATLVTVKHELFKEARKYPLYH
LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILSREIGFA
IGMPICEFDLVKDPEVQDFRRNILNVCKEAVDLRDNNGPHSRALYVYPPNVESSTDLPRH
IYNKLDKGQIIVVIWVIISPSNDKQKYTLKISHDCVPEQVIAEAIRKKTRSMLLSQEQLK
MCVQEYQGKYILKVCGCDEYLLEKYPLSQYKYVRSCIMLGRMPNLMLMSKDSLYSQLPSD
NFTMPSYARRISTATSYMNGETSSKNLWTINGMLKIRILCATYVNVNIRDIDKIYVRTGI
YHGGEQLCDNVNTLRVPCSNPRWNEWLSYDMYILEIPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINLFDYTHTLVAGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFEQF
SSPVKFPDMAYVEEHANWNISRELGFNYSHTGLSNRLARDNPLTDNDNEQLRQVCNRDPL
SEITEQEKDFLWRHRHSCINIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAME
LLDCNFPDPMIREFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLK
QEKKDEAQKVQMKFLVEQMRRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLW
LNWENPDMMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWIKDKNKGEMYDQAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKEDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKSEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRQHAMN
NT seq 3207 nt   +upstreamnt  +downstreamnt
atgcctcccagaccctcctcaggagaattatgggggatgcacttgatgccccccagcatt
gtggtggactgccttttgcccaatggcatgattctgtcactggagtgcctcagagaagcc
acgctcgtcaccgtcaagcacgagctcttcaaggaggccaggaagtacccgctttaccat
ttgctccaagaagaaagctcctacatcttcgtcagcgtcacccaagaggcggagagggag
gagttttacgacgagaccaggaggttatgtgatcttaggctcttccaggccttcctcaaa
gttattgagccagtgggcaacagagaggagaaaattctcagcagggaaataggttttgct
attggaatgcctatctgtgagtttgatttggtaaaagacccggaagtacaggacttcaga
aggaacattttaaacgtttgcaaagaagcggtggacctcagagacaataacggcccacat
agcagagctttgtacgtctaccccccaaacgtagaatcctcgacagaccttcccaggcac
atctataataagctagataaaggtcaaatcattgttgtcatctgggtgattatttcaccc
agcaacgacaaacagaagtacaccttgaagatcagccacgactgtgtgccggagcaggtg
atcgccgaagccatccgtaagaagacgcggagcatgctgctgtcacaggaacagctgaag
atgtgcgtccaggagtatcagggaaagtacatcctcaaagtctgtggctgtgacgagtac
ctgctggagaaatatcctctgagtcagtacaagtacgtgcgcagttgtatcatgctggga
aggatgcccaacctgatgctgatgtccaaagacagcctgtactcccagctgccctcagac
aacttcaccatgccgtcgtacgcaaggcgcatctcgacggcaacgtcctacatgaacggg
gaaacctcttctaagaatctttggaccatcaacggaatgctgaagatccggatactctgc
gccacctacgtcaatgtaaacatcagagatatcgacaagatctatgtcaggactggaata
taccacggtggggagcagttgtgtgacaacgtcaacaccctgcgtgtgccctgctcaaac
ccaaggtggaacgagtggctgagctacgacatgtacattctagaaatccccagagctgct
cgactctgcctctctatctgctctgtgaaaggaaggaagggcgccaaagaggaacattgt
cccttagcctggggcaacatcaacctgtttgactacacccacacgctggtagcagggaaa
atggctctcaacctgtggcctgtcccacatggcctggaggacctgctcaaccccatcggc
gtcacaggctccaaccccaacaaggaaaccccgtgtctggagctggagtttgaacagttc
agctctcccgtcaagtttccagatatggcgtacgtggaggagcacgccaactggaatata
tccagagagctgggtttcaattacagccacaccggcttgagtaacagattggcgcgcgac
aaccccctgaccgacaacgacaacgagcagctccggcaagtgtgcaacagagacccgctg
tcagaaatcactgagcaggagaaggacttcctgtggaggcacaggcattcctgcatcaat
atacccgagatccttcccaaaatcctcctggctgtgaagtggaactccagggatgaagtt
gctcagatgtattgccttctgaaagactggcctgcaataaagccagaacaagccatggag
ctgctggattgcaacttcccagatcctatgatcagagagtttgccgtcaagtgccttgag
aaatacctgactgatgataaactctctcagtatcttattcagctggttcaggttttaaaa
tatgagcagtaccttgataacccacttgcacgtttcctgttgaaaaaggctttaaccaat
caaaggataggacatttcttcttctggcatttaaaatcagagatgcacaacaagacggtg
agccagcggttcggcctgctgctggagtcctactgccgggcctgtggcatgtacctgaag
cacctgagccggcaggtggaggccatggagaagctaatcaatctcaccgacctcctcaaa
caggagaaaaaagatgaggcgcagaaggttcaaatgaagtttctggttgagcagatgagg
aggcccgactacatggatgcactacaaagcttcacctcacctctcaatccagcacatcag
ctgggaaacctgcgcctggaagagtgcaggatgatgtcttcggcaaagcggcctctctgg
ttgaactgggaaaacccggacatgatgtcagaactgctttttcagaacaacgagatcatt
ttcaaaaatggagacgatctgaggcaggacatgctgacgctgcagatcattaggataatg
gagaacatctggcaaaaccagggccttgatctcaggatgcttccgtacggctgcctgtcc
atcggggactgcgtgggtttaatcgaggtggtgaggaactctcacaccatcatgcaaatc
cagtgcaagggaggtctaaagggggcgctgcagttcaacagccacacactgcaccagtgg
atcaaagataagaacaagggagagatgtacgaccaggctattgatctcttcacgcggtcc
tgtgcaggctactgtgtggccaccttcatcctcggtataggagacagacacaacagcaat
atcatggtcaaagaagatggacagctgtttcacatcgactttggtcatttcctggaccac
aaaaagaagaagtttggctacaagagagagcgcgtcccgtttgtgctcacacaggacttc
ttgattgtcatcagcaaaggaacccaggagtgcaccaaaaccagggagtttgaaaggttt
caggaaatgtgttacaaagcttacttggccatccgccagcacgccaacctcttcatcaac
ctgttctccatgatgctgggctccggcatgccggagctgcagtccttcgacgacatcgcg
tacatcaggaagaccctggcgctggacaagtccgagcaggaggcgctggactacttcatg
aagcagatgaacgacgcccaccatggcggctggaccaccaagatggactggatcttccac
acaatccgccagcacgctatgaactaa

  All links  
Gene (17)   
   RefGene (14)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   RefSeq(pep) (2)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (9)   
   Pfam (9)   
All databases (31)   

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