KEGG   Pan troglodytes (chimpanzee): 463718
Entry
463718            CDS       T01005                                 
Symbol
SMO
Name
(RefSeq) protein smoothened isoform X1
  KO
K06226  smoothened
Organism
ptr  Pan troglodytes (chimpanzee)
Pathway
ptr04340  Hedgehog signaling pathway
ptr04360  Axon guidance
ptr05200  Pathways in cancer
ptr05205  Proteoglycans in cancer
ptr05217  Basal cell carcinoma
Brite
KEGG Orthology (KO) [BR:ptr00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04340 Hedgehog signaling pathway
    463718 (SMO)
 09150 Organismal Systems
  09158 Development and regeneration
   04360 Axon guidance
    463718 (SMO)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    463718 (SMO)
   05205 Proteoglycans in cancer
    463718 (SMO)
  09162 Cancer: specific types
   05217 Basal cell carcinoma
    463718 (SMO)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors [BR:ptr04030]
    463718 (SMO)
G protein-coupled receptors [BR:ptr04030]
 Frizzled / Smoothened family
  463718 (SMO)
SSDB
Motif
Pfam: Frizzled Fz Dicty_CAR DUF7470
Other DBs
NCBI-GeneID: 463718
NCBI-ProteinID: XP_016800863
Ensembl: ENSPTRG00000019680 ENSPTRG00000047167
VGNC: 4508
UniProt: H2QVC7
Position
6:144542821..144567717
AA seq 786 aa
MAAARPARGPELPLLGLLLLLLGGPGRGSASSGNATGPGPRSAGGSARRSAAVTGPPPPL
SHCGRAAPCEPLRYNVCLGSVLPYGATSTLLAGDSDSQEEAHGKLVLWSGLRNAPRCWAV
IQPLLCAVYMPKCENDWVELPSRTLCQATRGPCAIVERERGWPDFLRCTPDRFPEGCTNE
VQNIKFNSSGQCEVPLVRTDNPKSWYEDVEGCGIQCQNPLFTEAEHQDMHSYIAAFGAVT
GLCTLFTLATFVADWRNSNRYPAVILFYVNACFFVGSIGWLAQFMDGARREIVCRADGTM
RLGEPTSNETLSCVIIFVIVYYALMAGVVWFVVLTYAWHTSFKALGTTYQPLSGKTSYFH
LLTWSLPFVLTVAILAVAQVDGDSVSGICFVGYKNYRYRAGFVLAPIGLVLIVGGYFLIR
GVMTLFSIKSNHPGLLSEKAASKINETMLRLGIFGFLAFGFVLITFSCHFYDFFNQAEWE
RSFRDYVLCQANVTIGLPTKQPIPDCEIKNRPSLLVEKINLFAMFGTGIAMSTWVWTKAT
LLIWRRTWCRLTGQSDDEPKRIKKSKMIAKAFSKRHELLQNPGQELSFSMHTVSHDGPVA
GLAFDLNEPSADVSSAWAQHVTKMVARRGAILPQDISVTPVATPVPPEEQANLWLVEAEI
SPELQKRLGWKKKRRKKKKEVCPLAPPPELHPPAPAPSTIPRLPQLPRQKCLVAAGAWGA
GDSCRQGVWTLVSNPFCPEPSPPQDPFLPSAPAPMAWAHGRRQGLGPIHSRTNLMDAELM
DADSDF
NT seq 2361 nt   +upstreamnt  +downstreamnt
atggccgctgcccgcccagcgcgggggccggagctcccgctcctggggctgctgctgttg
ctgctggggggcccgggccgggggtcggcctcgagcgggaacgcgaccgggcctgggcct
cggagcgcgggcgggagcgcgaggaggagcgcggcggtgaccggccctccgccgccgctg
agccactgcggccgggctgccccctgcgagccgctgcgctacaacgtgtgcctgggctcg
gtgctgccctacggggccacctccacactgctggccggagactcggactcccaggaggaa
gcgcacggcaagctcgtgctctggtcgggcctccggaatgccccccgctgctgggcagtg
atccagcccctgctgtgtgccgtatacatgcccaagtgtgagaatgactgggtggagctg
cccagccgcaccctctgccaggccacccgaggcccctgtgccatcgtggagagggaacgg
ggctggcctgacttcctgcgctgcactcctgaccgcttccctgaaggctgcacgaatgag
gtgcagaacatcaagttcaacagttcaggccagtgcgaagtgcccttggttcggacagac
aaccccaagagctggtacgaggacgtggagggctgcggcatccagtgccagaacccgctc
ttcacagaggctgagcaccaggacatgcacagctacatcgcggccttcggggccgtcacg
ggcctctgcacgctcttcaccctggccacattcgtggctgactggcggaactcgaatcgc
taccctgctgttattctcttctacgtcaatgcgtgcttctttgtgggcagcattggctgg
ctggcccagttcatggatggtgcccgccgagagatcgtctgccgtgcagatggcaccatg
aggcttggggagcccacctccaatgagactctgtcctgcgtcatcatctttgtcatcgtg
tactacgccctgatggctggtgtggtttggtttgtggtcctcacctatgcctggcacact
tccttcaaagccctgggcaccacctaccagcctctctcgggcaagacctcctacttccac
ctgctcacctggtcactcccctttgtcctcactgtggcaatccttgctgtggcgcaggtg
gatggggactctgtgagtggcatttgttttgtgggctacaagaactaccgataccgtgcg
ggcttcgtgctggccccaatcggcctggtgctcatcgtgggaggctacttcctcatccga
ggagtcatgactctgttctccatcaagagcaaccaccccgggctgctgagtgagaaggct
gccagcaagatcaacgagaccatgctgcgcctgggcatttttggcttcctggcctttggc
tttgtgctcattaccttcagctgccacttctacgacttcttcaaccaggctgagtgggag
cgcagcttccgggactatgtgctatgtcaggccaatgtgaccatcgggctgcccaccaag
cagcccatccctgactgtgagatcaagaatcgcccgagccttctggtggagaagatcaac
ctgtttgccatgtttggaactggcatcgccatgagcacctgggtctggaccaaggccacg
ctgctcatctggaggcgtacctggtgcaggttgactgggcagagtgacgatgagccaaag
cggatcaagaagagcaagatgattgccaaggccttctccaagcggcacgagctcctgcag
aacccaggccaggagctgtccttcagcatgcacactgtgtcccacgatgggcccgtggcg
ggcttggcctttgacctcaatgagccctcagctgatgtctcctctgcctgggcccagcat
gtcaccaagatggtggctcggagaggagccatactgccccaggatatttctgtcacccct
gtggcaactccagtgcccccagaggaacaagccaacctgtggctggttgaggcagagatc
tccccagagctgcagaagcgcctgggctggaagaagaagaggaggaagaagaagaaggag
gtgtgccctctggcaccgccccctgagcttcacccccctgcccctgcccccagtaccatt
cctcgactgcctcagctgccccggcagaaatgcctggtggctgcaggtgcctggggagct
ggggactcttgccgacagggagtgtggaccctggtctccaacccattctgcccagagccc
agtccccctcaggatccatttctgcccagtgcaccggcccccatggcatgggctcatggc
cgccgacagggcctggggcctattcactcccgcaccaacctgatggacgcagaactcatg
gatgcagactcggacttctga

  All links  
Gene (6)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (2)   
   OC (1)   
   VGNC (1)   
Protein sequence (3)   
   UniProt (1)   
   RefSeq(pep) (2)   
DNA sequence (13)   
   RefSeq(nuc) (3)   
   GenBank (5)   
   EMBL (5)   
Protein domain (4)   
   Pfam (4)   
All databases (26)   

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