KEGG   Herpailurus yagouaroundi (jaguarundi): 121022112
Entry
121022112         CDS       T07555                                 
Symbol
CACNA1C
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1C isoform X1
  KO
K04850  voltage-dependent calcium channel L type alpha-1C
Organism
pyu  Herpailurus yagouaroundi (jaguarundi)
Pathway
pyu04010  MAPK signaling pathway
pyu04020  Calcium signaling pathway
pyu04022  cGMP-PKG signaling pathway
pyu04024  cAMP signaling pathway
pyu04260  Cardiac muscle contraction
pyu04261  Adrenergic signaling in cardiomyocytes
pyu04270  Vascular smooth muscle contraction
pyu04713  Circadian entrainment
pyu04720  Long-term potentiation
pyu04723  Retrograde endocannabinoid signaling
pyu04724  Glutamatergic synapse
pyu04725  Cholinergic synapse
pyu04726  Serotonergic synapse
pyu04727  GABAergic synapse
pyu04728  Dopaminergic synapse
pyu04742  Taste transduction
pyu04911  Insulin secretion
pyu04912  GnRH signaling pathway
pyu04921  Oxytocin signaling pathway
pyu04924  Renin secretion
pyu04925  Aldosterone synthesis and secretion
pyu04927  Cortisol synthesis and secretion
pyu04929  GnRH secretion
pyu04930  Type II diabetes mellitus
pyu04934  Cushing syndrome
pyu04935  Growth hormone synthesis, secretion and action
pyu05010  Alzheimer disease
pyu05020  Prion disease
pyu05022  Pathways of neurodegeneration - multiple diseases
pyu05031  Amphetamine addiction
pyu05207  Chemical carcinogenesis - receptor activation
pyu05410  Hypertrophic cardiomyopathy
pyu05412  Arrhythmogenic right ventricular cardiomyopathy
pyu05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:pyu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    121022112 (CACNA1C)
   04020 Calcium signaling pathway
    121022112 (CACNA1C)
   04024 cAMP signaling pathway
    121022112 (CACNA1C)
   04022 cGMP-PKG signaling pathway
    121022112 (CACNA1C)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    121022112 (CACNA1C)
   04929 GnRH secretion
    121022112 (CACNA1C)
   04912 GnRH signaling pathway
    121022112 (CACNA1C)
   04921 Oxytocin signaling pathway
    121022112 (CACNA1C)
   04935 Growth hormone synthesis, secretion and action
    121022112 (CACNA1C)
   04924 Renin secretion
    121022112 (CACNA1C)
   04925 Aldosterone synthesis and secretion
    121022112 (CACNA1C)
   04927 Cortisol synthesis and secretion
    121022112 (CACNA1C)
  09153 Circulatory system
   04260 Cardiac muscle contraction
    121022112 (CACNA1C)
   04261 Adrenergic signaling in cardiomyocytes
    121022112 (CACNA1C)
   04270 Vascular smooth muscle contraction
    121022112 (CACNA1C)
  09156 Nervous system
   04724 Glutamatergic synapse
    121022112 (CACNA1C)
   04727 GABAergic synapse
    121022112 (CACNA1C)
   04725 Cholinergic synapse
    121022112 (CACNA1C)
   04728 Dopaminergic synapse
    121022112 (CACNA1C)
   04726 Serotonergic synapse
    121022112 (CACNA1C)
   04720 Long-term potentiation
    121022112 (CACNA1C)
   04723 Retrograde endocannabinoid signaling
    121022112 (CACNA1C)
  09157 Sensory system
   04742 Taste transduction
    121022112 (CACNA1C)
  09159 Environmental adaptation
   04713 Circadian entrainment
    121022112 (CACNA1C)
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    121022112 (CACNA1C)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    121022112 (CACNA1C)
   05020 Prion disease
    121022112 (CACNA1C)
   05022 Pathways of neurodegeneration - multiple diseases
    121022112 (CACNA1C)
  09165 Substance dependence
   05031 Amphetamine addiction
    121022112 (CACNA1C)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    121022112 (CACNA1C)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    121022112 (CACNA1C)
   05414 Dilated cardiomyopathy
    121022112 (CACNA1C)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    121022112 (CACNA1C)
   04934 Cushing syndrome
    121022112 (CACNA1C)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:pyu04040]
    121022112 (CACNA1C)
Ion channels [BR:pyu04040]
 Voltage-gated cation channels
  Calcium channel, voltage-gated (Cav)
   121022112 (CACNA1C)
SSDB
Motif
Pfam: Ion_trans Ca_chan_IQ GPHH CAC1F_C PKD_channel
Other DBs
NCBI-GeneID: 121022112
NCBI-ProteinID: XP_040318950
Position
Unknown
AA seq 2193 aa
MNANAAAGLAPEHIPTPGAALSWQAAIDAARQAKLMGSAGNATISTISSTQRKRQQYGKP
KKQGSTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCVALAIYIPFPE
DDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFS
AILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLL
HIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGIADVPAEDDPSPCALETGHGRQCQNG
TVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWMQDAMGYELPWVYFVSLV
IFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDP
ENEDEGMDEEKPRNRSTPAGLLDQKKGKFAWFSHSTETHVSMPTSETESVNTENVAGGDI
EGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASE
HYNQPHWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFIVCGGILETI
LVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIII
FSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSF
PGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASP
EKKQEIMEKPAVEETKEEKIELKSITADGESPPTTKINMDDLQPNENEDKSPYPNPENTG
EDDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSPNNRFRLQCHRIVNDTIFTN
LILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKILGNADYVFTSIF
TLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLR
PLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQ
TEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRS
IDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDK
NQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQS
CLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETN
HYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPFMNAEENSRISITFFRLFRVMRL
VKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRN
NNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYF
ISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLD
VVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEG
NLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKE
QGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIF
RRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGNSQGDTESPSHEKLVDSTFTPS
SYSSTGSNANINNANNTALGRFPRPAGYPSAVSTVEGHGPPLSPAVRVQEAAWKLSSKRI
HCYDVLGRCHSRESQIAMVCQEEVSQDETYDVKISEDTEYCSEPSLISTEMLSYQDDENR
QLTPPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKNQGGDISQKTVLPLHLVHH
QALAVAGLSPLLQRSHSPSTSPRPCATPPATPSSRGWPPQPIPTLRLEGAESNEKLNSSF
PSIHCSSWSGEPTPCGGGGSTIRRARPVSLTVPGQAGAQGRQFHGSASSLVEAVLISEGL
GQFAQDPKFIEVTTQELADACDMTIEEMENAADNILSGGAQQSPNGTLLPFVNCRDPGQD
RAEGQEGETCAPTLACRKSEEELQDSRAHVGSL
NT seq 6582 nt   +upstreamnt  +downstreamnt
atgaatgccaatgcggctgcggggctcgcccccgagcacatcccaacgcccggggcagcc
ttgtcctggcaggcagccatcgacgcggcccggcaggctaagctgatgggcagcgctggc
aatgcaaccatctccaccatcagctccacacagcggaagcggcagcaatatgggaaaccc
aagaagcagggcagcacgactgccacacgcccgccccgtgccctgctctgcctgactctg
aagaaccccatcaggagggcgtgcatcagcatcgtcgaatggaaaccatttgaaataatt
attttactgactatttttgccaattgtgtggccttagcgatctatattccctttccagaa
gatgactccaatgccaccaattccaacctggaacgagtggaatatctctttctcataatt
tttactgtggaagcatttttaaaagtaatagcctatggacttctctttcaccccaacgct
tacctccgcaatggctggaatttactagattttataattgtggttgtagggctttttagt
gcaattttagaacaagccaccaaagctgacggggcaaatgctctaggagggaaaggagct
ggatttgatgtgaaggcactgagggcattccgcgtgctgcgccccttgcggctggtgtct
ggagtcccaagtctccaagtcgttctgaattccattatcaaggccatggtccccctgctg
catattgccctgttagtgctatttgtcatcatcatctacgctatcattggcctggagctc
ttcatgggaaagatgcataagacctgctacaaccaggagggcatagcagatgttccagca
gaagatgatccttccccttgtgctctggagactggccatgggcggcagtgccagaatggc
actgtgtgcaagcctggctgggacgggcccaagcacggcatcaccaactttgacaatttt
gccttcgccatgttgacagtgttccagtgcatcaccatggagggctggacagatgtgcta
tactggatgcaggacgctatgggctatgagttaccctgggtgtattttgtcagtctggtc
atctttggatcctttttcgttctaaatctggttctcggtgtgttgagcggagagttttcc
aaagagagagagaaggccaaggctcggggagacttccagaagctgcgagagaagcagcag
ctggaagaggacctgaagggctacctggactggatcacccaggcagaggacatcgaccct
gagaacgaggatgaaggcatggatgaggagaagccccgaaacagaagcactccagcgggc
ttgcttgatcagaagaaagggaagtttgcttggtttagtcactccacagaaacccatgtg
agcatgcccacaagtgagaccgagtctgtcaacaccgaaaacgtggctggaggtgacatc
gagggagagaactgcggggccaggctggcccatcggatttccaaatcaaagttcagccgc
tactggcgtcggtggaatcggttctgcagaagaaagtgtcgtgctgcagtcaagtctaat
gtcttctactggcttgtgatcttcctggtgttcctcaacacactcaccattgcctcagaa
cattacaaccagccccactggctcacagaggtccaagacacagccaacaaggcactactg
gcccttttcactgcggagatgctgctaaagatgtacagcctgggcctgcaggcctacttt
gtgtccctcttcaaccgctttgactgcttcatcgtgtgtgggggcattctggagactatc
ctggtggagaccaagatcatgtctcccttgggcatctctgtgctgagatgtgtccggcta
ctgcggatatttaaaatcacaaggtactggaactccttaagcaacctggtggcatccttg
ctgaattctgtgcgctccattgcctccctgctgctactcctcttcctcttcatcatcatc
ttctccctcctggggatgcagctctttggaggaaagttcaactttgatgagatgcagact
cggaggagcacatttgataactttcctcagtccctcctcaccgtgtttcagatcctgacc
ggggaggactggaattcggtgatgtatgatgggatcatggcttatggcggcccctctttt
ccagggatgttagtctgtatttacttcatcatcctcttcatctgtggaaactatatccta
ctgaatgtgttcttggccattgctgtggacaatctggctgatgctgagagcctcacatct
gcccaaaaggaggaggaagaagagaaggagagaaagaagctggccaggactgccagccca
gagaagaagcaagagataatggaaaagccagctgtggaggaaaccaaggaggagaaaatt
gagctgaaatccattacagctgatggagagtccccacccaccaccaagatcaacatggat
gacctccagcccaatgaaaatgaagataagagtccctaccccaacccagaaaatacagga
gaagacgatgaagaggagcctgagatgcctgtgggcccccgcccacgaccactctctgag
ctgcaccttaaggaaaaggcagtgcccatgccagaagccagtgcatttttcatcttcagc
cccaacaacagatttcgcctccagtgccaccgcattgtcaatgacacgatcttcaccaac
ctgatcctcttcttcattctgctcagcagcatttccctggcagctgaggaccctgtccag
cacacctccttcaggaaccatattctgttttattttgacattgttttcactaccattttc
accattgaaattgctctgaagatcctaggcaatgcagactatgtcttcactagtatcttt
acattagaaattatccttaagatgactgcttatggggctttcctacacaagggctctttc
tgccggaactacttcaacatcttggacctgctggtggtcagcgtgtccctcatctccttt
ggcatccagtccagtgcaattaatgtggtgaagatcttgcgagttctgcgagtcctcagg
cccctgagggccatcaacagggccaaggggctaaagcacgtggtccagtgcgtgtttgtt
gccatccggaccatagggaatatcgtgattgtcaccacgctgctccagttcatgttcgcc
tgcatcggggtccagcttttcaagggaaagctctacacctgttcagatagttccaagcag
actgaggcggaatgcaagggtaactacatcacatacaaggatggggaagttgaccacccc
atcatccagcctcgcagctgggaaaacagcaagtttgactttgacaatgttctggcagcc
atgatggccctctttactgtctccacctttgaggggtggccagagctgctgtaccgctcc
atcgactcccacacagaagacaagggccccatctacaactaccgtgtggagatctccatc
tttttcatcatctacatcattatcattgccttcttcatgatgaacatcttcgtgggtttt
gtcatcgtcaccttccaggagcagggggagcaggaatacaagaactgtgaactggacaag
aaccagcgacagtgtgtggaatatgccctcaaggcccggcccctgcgaaggtacatcccc
aaaaaccagcaccagtacaaagtgtggtacgtggtcaactccacctactttgaatacctg
atgttcgtcctcatcctgctcaacaccatctgcttggcaatgcagcactatggccagagc
tgcctattcaaaatcgccatgaacatcctcaacatgctcttcactggcctcttcactgtg
gagatgattctgaagctcattgccttcaaacccaagggttactttagtgatccctggaat
gtttttgacttcctcatcgtaattggcagcataattgacgtcattctcagtgaaactaat
cactatttctgtgatgcatggaatacatttgacgccttgattgttgtgggtagcattgtt
gatatagcaatcaccgaggtaaacccagctgaacatacccaatgctctccctttatgaac
gcagaggagaactcccgcatctccatcaccttcttccgcctcttccgggtcatgcgcctg
gtcaagctgctaagccgtggggagggcatccggaccctgctgtggaccttcatcaagtcc
ttccaggctttgccctatgtggcccttctgatagtgatgctgttcttcatctacgcagtg
atcgggatgcaggtgtttgggaaaattgccctgaatgacaccacagagatcaaccggaac
aacaactttcagaccttcccccaagctgtgctccttctcttcaggtgtgccacaggggag
gcatggcaagacatcatgctggcctgcatgccagggaagaagtgtgcccccgagtcagag
cccagcaacagcacggaaggggaaacgccctgtggcagcagttttgccgtcttctacttc
atcagcttctacatgctctgtgccttcctgatcatcaacctctttgtagctgtcatcatg
gacaactttgactacctgacaagagactggtcaatccttggtccccatcatctggatgaa
tttaaaagaatctgggcagagtatgatcctgaagctaagggtcgtatcaaacacctagat
gtggtgaccctgctcaggcggattcagcccccactgggttttgggaagctgtgccctcac
cgcgtggcttgcaaacgtctggtctccatgaacatgcctctgaacagtgatgggactgtc
atgttcaatgccaccctgtttgccctagtccggacagccctgcggatcaaaacagaaggg
aacctagaacaagccaatgaggagctgcgggccataatcaagaagatctggaagcgtacc
agcatgaagctgctagaccaagtggtgccccctgcaggtgatgatgaggtcaccgttggc
aagttttatgctactttcctgatccaagagtacttccggaaattcaagaagcgcaaagag
cagggccttgtgggcaagccttcccaaaggaacgccctgtccttgcaggctggcttgcgc
acgctgcatgacattgggcctgagatccgacgggccatctctggagatctgacagctgag
gaggagctggacaaggccatgaaggaggctgtgtctgctgcctccgaagatgacatcttc
aggagggccggtggcctgttcggcaaccacgtcagctactaccaaagcgacggccggagc
gccttcccccagaccttcaccacccagcgcccactgcacatcaacaaggcgggtaacagc
caaggcgacaccgagtcgccatcccacgagaaactggtggactccaccttcacccccagc
agctactcgtccactggctccaacgccaacatcaacaatgccaacaacactgccctgggc
cgcttcccccgtcccgctggctaccccagcgcagtcagcaccgtggagggccatgggccc
cccttgtctcctgctgtccgggtacaggaggcagcatggaagctcagctccaagaggata
cattgctatgatgtgctgggacggtgccactcccgggagagccagatagccatggtgtgt
caggaggaggtctctcaggacgagacctatgacgtgaagataagtgaagacactgagtac
tgcagcgagcccagcctgatctccacagagatgctctcctatcaggatgatgaaaatcgg
caattaacaccaccggaggaggacaagagagatatccggcaatctccaaagaggggcttc
ctccgctctgcctcactaggtcgaagggcctccttccacctggaatgtctgaagcgacag
aagaatcaagggggagacatctctcagaagacagtcctgcccttgcatctggttcatcat
caggcattggcggtggcaggcctgagccccctcctccagagaagccattcccccagcaca
tcccccaggccctgtgccaccccaccagccactccaagcagccgaggctggcccccacag
cctatccccaccctgcggctggagggtgctgaatccaacgagaaactcaacagcagcttc
ccgtccatccactgcagctcctggtctggagagcccacaccctgtggtggaggtggcagc
accatccggagagcccggccagtgtccctcactgtgcccggccaggctggggcccagggc
aggcagttccacggcagtgccagcagcctggtagaagcggtcttgatttcagaaggactg
gggcagtttgctcaagatcccaagtttattgaggtcacaacccaggagctggctgacgcc
tgtgacatgaccatagaggagatggagaacgccgcagacaacatcctcagtgggggcgcc
cagcagagccccaatggcaccctactacctttcgttaactgcagggacccagggcaggac
agagcagagggccaagagggcgagacctgcgcgcccaccctggcgtgtcggaagagcgag
gaggagctccaggacagcagagcccacgtcggcagcctgtag

  All links  
Gene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (23)   
   RefSeq(pep) (23)   
DNA sequence (23)   
   RefSeq(nuc) (23)   
Protein domain (5)   
   Pfam (5)   
All databases (53)   

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