KEGG   Sarcophilus harrisii (Tasmanian devil): 100919750
Entry
100919750         CDS       T02286                                 
Symbol
CACNA1D
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1D isoform X1
  KO
K04851  voltage-dependent calcium channel L type alpha-1D
Organism
shr  Sarcophilus harrisii (Tasmanian devil)
Pathway
shr04010  MAPK signaling pathway
shr04020  Calcium signaling pathway
shr04022  cGMP-PKG signaling pathway
shr04024  cAMP signaling pathway
shr04218  Cellular senescence
shr04260  Cardiac muscle contraction
shr04261  Adrenergic signaling in cardiomyocytes
shr04270  Vascular smooth muscle contraction
shr04530  Tight junction
shr04713  Circadian entrainment
shr04723  Retrograde endocannabinoid signaling
shr04724  Glutamatergic synapse
shr04725  Cholinergic synapse
shr04726  Serotonergic synapse
shr04727  GABAergic synapse
shr04728  Dopaminergic synapse
shr04911  Insulin secretion
shr04912  GnRH signaling pathway
shr04921  Oxytocin signaling pathway
shr04924  Renin secretion
shr04925  Aldosterone synthesis and secretion
shr04927  Cortisol synthesis and secretion
shr04929  GnRH secretion
shr04930  Type II diabetes mellitus
shr04934  Cushing syndrome
shr04935  Growth hormone synthesis, secretion and action
shr04973  Carbohydrate digestion and absorption
shr05010  Alzheimer disease
shr05020  Prion disease
shr05022  Pathways of neurodegeneration - multiple diseases
shr05031  Amphetamine addiction
shr05207  Chemical carcinogenesis - receptor activation
shr05410  Hypertrophic cardiomyopathy
shr05412  Arrhythmogenic right ventricular cardiomyopathy
shr05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:shr00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100919750 (CACNA1D)
   04020 Calcium signaling pathway
    100919750 (CACNA1D)
   04024 cAMP signaling pathway
    100919750 (CACNA1D)
   04022 cGMP-PKG signaling pathway
    100919750 (CACNA1D)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    100919750 (CACNA1D)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    100919750 (CACNA1D)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    100919750 (CACNA1D)
   04929 GnRH secretion
    100919750 (CACNA1D)
   04912 GnRH signaling pathway
    100919750 (CACNA1D)
   04921 Oxytocin signaling pathway
    100919750 (CACNA1D)
   04935 Growth hormone synthesis, secretion and action
    100919750 (CACNA1D)
   04924 Renin secretion
    100919750 (CACNA1D)
   04925 Aldosterone synthesis and secretion
    100919750 (CACNA1D)
   04927 Cortisol synthesis and secretion
    100919750 (CACNA1D)
  09153 Circulatory system
   04260 Cardiac muscle contraction
    100919750 (CACNA1D)
   04261 Adrenergic signaling in cardiomyocytes
    100919750 (CACNA1D)
   04270 Vascular smooth muscle contraction
    100919750 (CACNA1D)
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    100919750 (CACNA1D)
  09156 Nervous system
   04724 Glutamatergic synapse
    100919750 (CACNA1D)
   04727 GABAergic synapse
    100919750 (CACNA1D)
   04725 Cholinergic synapse
    100919750 (CACNA1D)
   04728 Dopaminergic synapse
    100919750 (CACNA1D)
   04726 Serotonergic synapse
    100919750 (CACNA1D)
   04723 Retrograde endocannabinoid signaling
    100919750 (CACNA1D)
  09159 Environmental adaptation
   04713 Circadian entrainment
    100919750 (CACNA1D)
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    100919750 (CACNA1D)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    100919750 (CACNA1D)
   05020 Prion disease
    100919750 (CACNA1D)
   05022 Pathways of neurodegeneration - multiple diseases
    100919750 (CACNA1D)
  09165 Substance dependence
   05031 Amphetamine addiction
    100919750 (CACNA1D)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    100919750 (CACNA1D)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    100919750 (CACNA1D)
   05414 Dilated cardiomyopathy
    100919750 (CACNA1D)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    100919750 (CACNA1D)
   04934 Cushing syndrome
    100919750 (CACNA1D)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:shr04040]
    100919750 (CACNA1D)
Ion channels [BR:shr04040]
 Voltage-gated cation channels
  Calcium channel, voltage-gated (Cav)
   100919750 (CACNA1D)
SSDB
Motif
Pfam: Ion_trans CAC1F_C Ca_chan_IQ GPHH PKD_channel NCAPD3_N
Other DBs
NCBI-GeneID: 100919750
NCBI-ProteinID: XP_031807900
Position
1:9041155..9330813
AA seq 1898 aa
MVPLLHIALLVLFVIIIYAIIGLELFIGKMHKSCFFTDTDILAEDDPAPCAFSGNGRQCT
ANGTECRSGWVGPNGGITNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAIGWEWPWVYFV
SLIILGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAED
IDPENEDEGGEENKRSTSMPTSETESVNTENISGEGETQGCCGRLCQAISKSKLSRRWRR
WNRFSRRRCRAAVKSVSFYWLVIVLVFLNTLTISSEHYNQPDWLTQIQDIANKVLLAMFT
CEMLVKMYSLGLQAYFVSLFNRFDCFVVCGGITETILVELEIMSPLGISVFRCVRLLRIF
KVTRHWTSLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETQTKRST
FDNFPQALLTVFQILTGEDWNAVMYDGIMAYGGPSSSGMIVCIYFIILFICGNYILLNVF
LAIAVDNLADAESLNTAQKEEAEEKERKKTARKESLENKRNDKPEVNPMANSDHKVIIDD
YRGEDEDKDPYPPCDVPVGEEEEEEEDEPEVPAGPRPRRISELNMKEKIIPIPEGSAFFI
FSKTNPIRVGCHRLINHHIFTNLILVFIMLSSASLAAEDPIRSHSFRNIILGYFDYAFTA
IFTVEILLKMTTFGAFLHKGAFCRNYFNLLDMLVVGVSLVSFGIQSSAISVVKILRVLRV
LRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYRCTDEA
KSNPEECRGLFILYKDGDVNSPMVRERVWQNSDFNFDNVLSAMMALFTVSTFEGWPALLY
KAIDSNGENVGPIYNYRVEISIFFIIYIIIVAFFMMNIFVGFVIVTFQEQGEKEYKNCEL
DKNQRQCVEYALKARPLRRYIPKNPYQYKFWYVVNSSPFEYMMFVLIMLNTLCLAMQHYE
QSKIFNDAMDILNMVFTGVFTVEMVLKVIAFKPKHYFTDAWNTFDALIVVGSVVDIAITE
VNPTDNESSPVPVPTAAPGNSEESNRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKS
FQALPYVALLIAMLFFIYAVIGMQMFGKVAMKDNNQINRNNNFQTFPQAVLLLFRCATGE
AWQEIMLACLPGKRCDPESDYSPGEEFTCGSNFAIVYFISFYMLCAFLIINLFVAVIMDN
FDYLTRDWSILGPHHLDEFKRIWSEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRV
ACKRLVAMNMPLNSDGTVMFNATLFALVRTALKIKTEGNLEQANEELRAVIKKIWKKTSM
KLLDQVVPPAGDDEVTVGKFYATFLIQDYFRKFKKRKEQGLVGKYPAKNTTIALQAGLRT
LHDIGPEIRRAISCDLQDDEPEEKKQEEEEDVFKRNGALFGNHVNHVTSDRRDSLQQTNT
THRPLHVQRPSIPSASDTENPMFPPAGNSVYPNHHNHNSIGKQVPNSTNANLNNANMSKV
ANGKHPGIGNLEHVSENGYHSLHKHEHAPQRRSSITRTRYYETYIRSGSGDGQLPTICRE
DSEGYDYFGDDQCVGEQEYFSGDEYYEDDCMLVGSRPAVDFCHRGPGYGYGYGSAYERPW
ASQRPHGILDEDSPAHYESRRSPRRRLLPPTPTTNRRSSFNFECLRRQSSQDEITLSPSF
HHRAALPLHLMQQQIMAVAGLDSSKAQKYSPSHSTRSWATPPATPPYKDRTPYYTPLIQV
ERSDSLDQMNGSLPSLHRSSWYTDDPDISYRTFTPASLTIPSDFRHKHSDKQRSADSLVE
AVLISEGLGRYARDPKFVSATKHEIADACDMTIDEMESAASNLLNGNMSNGTNGDMCPIL
NRRDDEFPDFGPGYSDEEADPGRYEEDLADEMICITTL
NT seq 5697 nt   +upstreamnt  +downstreamnt
atggttcccctcctccacattgcccttttggtattatttgtaatcataatctatgctatt
ataggattggaactttttattgggaaaatgcacaaatcttgttttttcactgatacagat
atcttagccgaagacgacccagcaccttgtgcgttctcagggaatgggcgccagtgcacc
gccaatggcacggaatgtagaagtggatgggttggaccaaacggaggcataaccaacttt
gataattttgcctttgcaatgcttactgttttccaatgtattactatggaaggctggaca
gacgtgttgtactgggtaaatgatgcaataggatgggaatggccatgggtgtattttgtt
agtctgatcatccttggctcatttttcgtccttaacctggttcttggtgtgcttagtgga
gagttctcaaaggagagagagaaggccaaggcccggggggacttccagaagctccgcgag
aagcagcagctcgaggaagatctgaagggctatctggactggatcacgcaggctgaagac
atcgaccccgagaacgaggacgaaggcggggaggagaacaagcggagcacaagcatgccc
accagcgagacggagtccgtgaacacggaaaacatcagtggcgagggtgagacccaaggc
tgctgcggccggctctgtcaagcgatctccaaatccaagctcagccgacgttggcgtcgc
tggaaccgtttcagtcgaagaagatgccgagctgcagtgaaatcagtgtcgttctattgg
ctggtgattgtcctcgtgttcctcaacaccttgaccatttcctctgagcattataatcag
cctgactggctgacccagattcaagatattgccaacaaagttctcctggccatgttcacc
tgtgagatgctagtgaagatgtacagcctgggtctccaggcctattttgtctcccttttc
aatcggtttgattgttttgtggtgtgtggtgggatcactgagaccatcctggtggaactg
gaaatcatgtctcctctgggcatctctgtgtttcgatgtgtgcgtcttttgcgcattttc
aaagtgaccaggcattggacatctctcagcaacttggtagcgtctttgttaaactccatg
aagtccatcgcttctctcttgctccttctcttcctcttcatcatcatcttctccttgctt
ggaatgcagctgttcgggggcaaatttaactttgacgagacccagaccaagaggagcacc
ttcgataactttcctcaagctcttttaacagtgtttcagattcttacaggtgaagactgg
aatgctgtcatgtatgatggaattatggcctatggaggcccgtcttcttcaggaatgatc
gtctgtatatacttcattattctctttatttgtggtaattatattctgttaaatgttttc
ttggccattgcggtggacaatttggcggatgctgaaagtctgaatactgcccagaaggaa
gaagcagaggaaaaggaaaggaaaaagactgccagaaaagaaagtttggagaataaaagg
aacgacaagccagaagtcaacccgatggctaacagtgaccacaaggttataatcgatgat
tacagaggagaggatgaagacaaggacccttacccaccatgtgatgtcccagtaggagaa
gaggaggaggaggaagaagatgaaccagaggttcctgctggcccccgcccccgtcgaatc
tcagagttgaatatgaaggagaagatcatccccattcccgaaggaagcgcgttcttcatt
tttagcaaaacaaatccaattcgagtgggctgccacagacttatcaatcaccacatcttt
accaacctcatccttgtcttcatcatgctcagcagtgcgtccctcgctgctgaagacccc
attcggagccactcctttcggaatatcatactgggttactttgactatgctttcacagcc
atctttactgtcgaaatcctgttaaagatgacaacttttggagcattccttcacaaaggg
gcattctgtaggaattacttcaacttgctggatatgctggttgtgggcgtttctctggta
tcgtttgggatccaatcaagtgctatctccgtggtgaagattttgagggtcttaagggtc
ctgaggcctctcagggccatcaacagagcaaaaggacttaagcatgtggttcagtgtgtc
tttgtcgctattcgaaccataggcaacatcatgattgtcaccaccctgcttcagttcatg
tttgcctgcattggggtgcagctgtttaaggggaagttctaccggtgcacggatgaagcc
aaaagtaaccctgaagaatgcaggggactcttcatcctttacaaagatggcgatgttaat
agccccatggttcgggagagagtttggcaaaatagtgatttcaactttgacaatgttctc
tcggcgatgatggctcttttcacagtctccacatttgaaggatggcctgcgttattgtat
aaagcgatcgactccaatggggagaacgttggcccaatttacaactatcgggtggagatt
tctatcttctttatcatctacatcatcattgtggccttcttcatgatgaatatctttgtg
ggctttgtgattgtcacctttcaggagcagggggagaaagagtacaagaactgtgagctg
gacaagaaccagcgtcagtgtgtcgaatacgccttgaaagcccggcccctgcggagatac
attcccaaaaatccctaccagtacaagttctggtacgtggtgaactcctcccccttcgag
tacatgatgttcgtcctcatcatgctcaacactttgtgcttggccatgcagcattacgag
cagtccaagatcttcaatgatgccatggacatcctgaacatggtcttcacaggagtgttc
actgtggagatggtcctgaaagtcatcgcattcaaacccaagcactatttcactgatgca
tggaacacttttgatgccttaattgttgttggtagcgttgttgatatcgctattacggaa
gtgaatccaactgacaatgagagtagccccgtccctgtcccaaccgctgctcctgggaac
tcggaagagagcaatagaatttccatcacctttttccgtcttttccgagtgatgaggctg
gtgaagcttctcagcagaggggaaggaatccggacgctgctgtggacttttatcaaatct
tttcaggctctcccatatgttgcccttctcatagctatgttgttcttcatctatgctgtc
atcgggatgcagatgtttgggaaagtggccatgaaagataacaaccagatcaatagaaac
aacaatttccagacatttccgcaagctgtgttgctcttgttcaggtgtgccactggtgag
gcttggcaggaaatcatgctggcgtgtctccctgggaagcggtgcgacccggaatctgat
tatagtcctggggaggaattcacatgtggcagcaattttgccattgtttatttcatcagt
ttttatatgctctgtgcttttctgatcatcaatctgttcgtggctgtcatcatggacaac
tttgattatctgactcgtgactggtctattttgggtccacatcatttggatgaattcaag
agaatatggtcggaatatgacccagaagcgaaaggaagaattaagcacctcgatgtggtg
actctgctgcgccggatccagccgcccctggggtttggcaaactgtgcccacacagagta
gcctgcaagagattggttgccatgaacatgcctctcaatagtgatggaacggtcatgttt
aatgccacgttatttgccttggttcgaacggctctcaaaatcaagactgaaggcaatctg
gaacaggcaaatgaggagctgcgagcagtcatcaagaaaatatggaagaagaccagtatg
aagcttctggatcaagttgtccctccagctggtgatgatgaggtaaccgtggggaagttc
tatgccactttcctgatacaggactactttaggaaattcaagaaacgcaaagaacaaggc
ctggtgggaaagtaccctgcgaagaacaccacgattgctctacaggcaggattaaggacc
cttcatgatattgggccagaaatccgtcgcgctatatcatgtgatttgcaagatgatgaa
cccgaggaaaaaaaacaggaggaagaggaagatgtattcaaaagaaatggtgccttgttt
ggaaaccatgtcaatcatgtcactagtgataggagagattcccttcagcagacaaatacc
acccaccgtcccctgcatgtccaaaggccttcaattccatctgcaagcgatactgagaac
ccaatgtttcctccagcaggaaattcggtgtatcctaaccatcataaccataattccata
ggaaagcaagttcccaactcaacaaatgccaatctcaataatgccaatatgtccaaagtt
gctaacgggaagcaccccggcattggaaaccttgagcatgtgtctgaaaatgggtatcat
tcactccacaagcatgagcatgcgcctcaaagaaggtcaagtatcaccagaacccgctat
tacgaaacttacattaggtctggttccggtgacgggcagctccctaccatttgccgggaa
gactcggagggctatgactactttggggatgaccagtgcgtgggggagcaggagtatttc
agtggcgatgagtactatgaggacgactgcatgctggtgggcagcaggccagcggtggac
ttctgccacagaggccccggctacggttatggctacggctccgcctacgagaggccctgg
gcttcccagcgcccccacggcatcctggacgaggactccccggcccactacgagtccagg
agatctccccggagacggctgctgccccccacgcccacaacaaatcggaggtcatccttc
aactttgagtgcctgcgtaggcagagcagtcaagatgagatcactctgtctccttccttc
catcatcgtgcagctttgcccctgcacctgatgcagcaacagatcatggcagttgcaggc
ctggattctagtaaagctcagaagtactcaccaagtcactccacgcggtcatgggctact
ccaccagccacccctccgtacaaggatcggactccttactatactcccctgattcaagtg
gaaaggtctgactccctggatcagatgaacggaagcctgccctccttacaccggagctcc
tggtacacggacgaccccgacatctcctaccggacattcaccccggccagtctgaccatc
cccagcgacttcaggcacaagcacagtgacaagcagaggagcgccgacagcttggtggaa
gccgtcctgatctcagaaggcttaggtcgctacgctagggaccctaaatttgtgtctgct
acgaaacacgagatcgccgatgcctgtgacatgaccatcgatgagatggaaagcgcagca
agtaaccttctgaatggcaatatgagcaatgggaccaatggggacatgtgtcccatctta
aacagacgagacgacgaattccctgactttggtcctggttatagtgatgaggaagcagac
cctggtagatatgaagaggacttggctgatgagatgatatgcatcacaaccttatag

  All links  
Gene (32)   
   RefGene (29)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (4)   
   RefSeq(pep) (4)   
DNA sequence (4)   
   RefSeq(nuc) (4)   
Protein domain (6)   
   Pfam (6)   
All databases (46)   

Download RDF
DBGET integrated database retrieval system