KEGG   Streptomyces spinosirectus: LXH13_10995
Entry
LXH13_10995       CDS       T08958                                 
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
  KO
K01929  UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]
Organism
sspn  Streptomyces spinosirectus
Pathway
sspn00300  Lysine biosynthesis
sspn00550  Peptidoglycan biosynthesis
sspn01100  Metabolic pathways
sspn01502  Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:sspn00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00300 Lysine biosynthesis
    LXH13_10995
  09107 Glycan biosynthesis and metabolism
   00550 Peptidoglycan biosynthesis
    LXH13_10995
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01502 Vancomycin resistance
    LXH13_10995
Enzymes [BR:sspn01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.10  UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
     LXH13_10995
SSDB
Motif
Pfam: Mur_ligase_M Mur_ligase_C Mur_ligase APH DUF561 E1-E2_ATPase
Other DBs
NCBI-ProteinID: UIR17531
Position
complement(2370767..2372182)
AA seq 471 aa
MIALSLAEIAEVVGGQTHDIPDPSVQVTAPVVRDSREVEPGSLFVAFVGERVDGHDFAQQ
VVDAGAVAVLASRPVGVPAIVVEDVQTALGALARHVVRRLGATLVALTGSAGKTSTKDLI
AQVLQRKAPTVWTPGSLNNEIGLPLTALTATEETKFLVLEMGARGIGHIRYLAGLTPPRI
GLVLNVGTAHIGEFGGREQIAQAKGELVESLPSSDEGGTAVLNADDPLVRAMASRTKAKV
VLFGEADEADVRAENVRLTDTGQPAFRLRTPSGASDVTMRLYGEHHVSNALAAAAVAHEL
GMSAQEIATALSEAGSLSRWRMEVTERPDGVTIVNDAYNANPESMRAALRALVAMGRGRR
TWAVLGKMAELGDEALAEHDAVGRLAVRLNVGKLVAVGGREASWLQLGAYNEGSWGEESV
HVSDAQAAVDLLRSELRPGDVVLVKASRSVGLESVAQALLATGAEGEVAAR
NT seq 1416 nt   +upstreamnt  +downstreamnt
gtgatcgccctctctctcgccgagatcgcagaagtcgtcggcgggcagacgcacgacata
ccggatccgtccgtccaggtcaccgctccggtcgtccgggactcccgcgaggtggagccc
ggcagcctgttcgtcgccttcgtcggcgaacgagtggacggccacgacttcgcccagcag
gtcgtggacgcgggcgcggtcgccgtgctggcgtcgcgccccgtcggcgtgcccgcgatc
gtcgtcgaggacgtgcagacggcgctcggtgccctcgcccgtcatgtcgtacgacgcctc
ggcgccacgctcgtggccctcaccggctccgcgggcaagaccagcaccaaggacctcatc
gcccaggtgctgcagcgcaaggcgcccaccgtgtggacgcccggctcgctcaacaacgag
atcggactgccgctgaccgcgctgaccgccaccgaggagacgaagttcctcgtcctggag
atgggcgcccgcggcatcggccacatccgctacctcgcgggtctgacgccccccaggatc
ggcctcgtcctgaacgtcggcaccgcccacatcggcgagttcggcggccgggagcagatc
gcacaggccaagggcgaactcgtcgagtccctcccgtcgtcggacgagggcggcaccgcg
gtcctcaacgcggacgaccccctcgtacgggccatggcatcccgtacgaaggcgaaggtg
gtcctattcggagaggccgacgaagcggacgtacgcgccgagaacgtgcgactcacggac
accggacagcccgccttcaggcttcgcacaccctccggtgcaagcgatgtgaccatgcgc
ctgtacggtgagcaccacgtgtcgaacgcgctcgccgcggccgccgtcgcccatgagctg
ggcatgtccgcgcaagagatcgccaccgcgctctccgaggcgggctccctctcccgctgg
cgtatggaggtcaccgagcgaccggacggcgtgaccatcgtcaacgacgcctacaacgcc
aaccccgagtccatgcgggccgctctgcgcgcgctcgtggccatgggcagggggcggcgg
acctgggcggtgctcggcaagatggccgagctcggggacgaggcgctcgccgagcacgac
gcggtcggacggctcgccgtccggctcaatgtcggcaagctcgtcgcggtcgggggcagg
gaagcgtcctggctgcaactgggcgcatataacgagggttcgtggggtgaggagtcggtg
cacgtgtccgacgcacaggcggctgtcgacctgttgcgcagcgagttgcgcccgggggac
gtcgtgctcgtgaaggcgtcccgttcggtcggtctggagagtgtcgcccaggcgctgctc
gcgaccggtgccgagggtgaggttgccgcccgatga

  All links  
Gene (1)   
   NCBI-PROTEINID (1)   
Protein domain (6)   
   Pfam (6)   
All databases (7)   

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