KEGG   Trichosurus vulpecula (common brushtail): 118842597
Entry
118842597         CDS       T10126                                 
Symbol
SOS1
Name
(RefSeq) son of sevenless homolog 1
  KO
K03099  son of sevenless
Organism
tvp  Trichosurus vulpecula (common brushtail)
Pathway
tvp01521  EGFR tyrosine kinase inhibitor resistance
tvp01522  Endocrine resistance
tvp04010  MAPK signaling pathway
tvp04012  ErbB signaling pathway
tvp04014  Ras signaling pathway
tvp04062  Chemokine signaling pathway
tvp04068  FoxO signaling pathway
tvp04072  Phospholipase D signaling pathway
tvp04150  mTOR signaling pathway
tvp04151  PI3K-Akt signaling pathway
tvp04510  Focal adhesion
tvp04540  Gap junction
tvp04630  JAK-STAT signaling pathway
tvp04650  Natural killer cell mediated cytotoxicity
tvp04660  T cell receptor signaling pathway
tvp04662  B cell receptor signaling pathway
tvp04664  Fc epsilon RI signaling pathway
tvp04714  Thermogenesis
tvp04722  Neurotrophin signaling pathway
tvp04810  Regulation of actin cytoskeleton
tvp04910  Insulin signaling pathway
tvp04912  GnRH signaling pathway
tvp04915  Estrogen signaling pathway
tvp04917  Prolactin signaling pathway
tvp04926  Relaxin signaling pathway
tvp04935  Growth hormone synthesis, secretion and action
tvp05034  Alcoholism
tvp05160  Hepatitis C
tvp05161  Hepatitis B
tvp05163  Human cytomegalovirus infection
tvp05165  Human papillomavirus infection
tvp05200  Pathways in cancer
tvp05205  Proteoglycans in cancer
tvp05206  MicroRNAs in cancer
tvp05207  Chemical carcinogenesis - receptor activation
tvp05208  Chemical carcinogenesis - reactive oxygen species
tvp05210  Colorectal cancer
tvp05211  Renal cell carcinoma
tvp05213  Endometrial cancer
tvp05214  Glioma
tvp05215  Prostate cancer
tvp05220  Chronic myeloid leukemia
tvp05221  Acute myeloid leukemia
tvp05223  Non-small cell lung cancer
tvp05224  Breast cancer
tvp05225  Hepatocellular carcinoma
tvp05226  Gastric cancer
tvp05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:tvp00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    118842597 (SOS1)
   04012 ErbB signaling pathway
    118842597 (SOS1)
   04014 Ras signaling pathway
    118842597 (SOS1)
   04630 JAK-STAT signaling pathway
    118842597 (SOS1)
   04068 FoxO signaling pathway
    118842597 (SOS1)
   04072 Phospholipase D signaling pathway
    118842597 (SOS1)
   04151 PI3K-Akt signaling pathway
    118842597 (SOS1)
   04150 mTOR signaling pathway
    118842597 (SOS1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    118842597 (SOS1)
   04540 Gap junction
    118842597 (SOS1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    118842597 (SOS1)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    118842597 (SOS1)
   04660 T cell receptor signaling pathway
    118842597 (SOS1)
   04662 B cell receptor signaling pathway
    118842597 (SOS1)
   04664 Fc epsilon RI signaling pathway
    118842597 (SOS1)
   04062 Chemokine signaling pathway
    118842597 (SOS1)
  09152 Endocrine system
   04910 Insulin signaling pathway
    118842597 (SOS1)
   04912 GnRH signaling pathway
    118842597 (SOS1)
   04915 Estrogen signaling pathway
    118842597 (SOS1)
   04917 Prolactin signaling pathway
    118842597 (SOS1)
   04926 Relaxin signaling pathway
    118842597 (SOS1)
   04935 Growth hormone synthesis, secretion and action
    118842597 (SOS1)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    118842597 (SOS1)
  09159 Environmental adaptation
   04714 Thermogenesis
    118842597 (SOS1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    118842597 (SOS1)
   05206 MicroRNAs in cancer
    118842597 (SOS1)
   05205 Proteoglycans in cancer
    118842597 (SOS1)
   05207 Chemical carcinogenesis - receptor activation
    118842597 (SOS1)
   05208 Chemical carcinogenesis - reactive oxygen species
    118842597 (SOS1)
   05231 Choline metabolism in cancer
    118842597 (SOS1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    118842597 (SOS1)
   05225 Hepatocellular carcinoma
    118842597 (SOS1)
   05226 Gastric cancer
    118842597 (SOS1)
   05214 Glioma
    118842597 (SOS1)
   05221 Acute myeloid leukemia
    118842597 (SOS1)
   05220 Chronic myeloid leukemia
    118842597 (SOS1)
   05211 Renal cell carcinoma
    118842597 (SOS1)
   05215 Prostate cancer
    118842597 (SOS1)
   05213 Endometrial cancer
    118842597 (SOS1)
   05224 Breast cancer
    118842597 (SOS1)
   05223 Non-small cell lung cancer
    118842597 (SOS1)
  09172 Infectious disease: viral
   05161 Hepatitis B
    118842597 (SOS1)
   05160 Hepatitis C
    118842597 (SOS1)
   05163 Human cytomegalovirus infection
    118842597 (SOS1)
   05165 Human papillomavirus infection
    118842597 (SOS1)
  09165 Substance dependence
   05034 Alcoholism
    118842597 (SOS1)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    118842597 (SOS1)
   01522 Endocrine resistance
    118842597 (SOS1)
SSDB
Motif
Pfam: RasGEF RasGEF_N RhoGEF SOS1_NGEF_PH PH PH_19 PH_10 RHG20_PH IQ_SEC7_PH
Other DBs
NCBI-GeneID: 118842597
NCBI-ProteinID: XP_036605926
Position
3:356006404..356156327
AA seq 1446 aa
MSLSKRVNSVKKRNHCPCYHQYHLLTNCQFKSKQTSPAKTARHSERDVSGSIWQAGTILT
TKLWWKQPKSSVPEGPVIMPSSHWLCFQLTFLTLCSHHPREKPLSRRNVTIIPITTKFNF
DGQISPRNRIAHHITGSQYNSTAVQMQVHPTLASNEDALQYVEELILQLLSMLCQAQPRS
VLDVEDRVQKSFPHPIDKWAIADAQSANEKRKRRNPLSLPVEKIHPLLKEVLGYKIDHQV
SVYIVAVLEYISADILKLVGNYVRNIRHYEITKQDIKVAMCADKVLMDMFHQDVEDINIL
SLTDEEPSTSGEQTYYDLVKAFMAEVRQYIRELNLIIKVFREPFVSNSKLFSSHDVENIF
SRIADVHELSVKLLGHIEDTVEMTDEGSPHPLVGSCFEDLAEELAFDPYESYAQDILRPG
FHDHFLSQLSKPGAALYLQSIGEGFKEAVQYVLPRLLLAPVYHCLHYFELLKQLEEKSED
QEDKECLKQAITALLNLQSSMERICSKSLAKRRLSESACRFYSQQMKGKQLAIKKMNEIQ
KNIDGWEGKDIGQCCNEFIMEGTLTRVGAKHERHIFLFDGLMICCKSNHGQPRLPGASNA
EYRLKEKFFMRKVQINDKDDTNEYKHSFEIILKDENSVIFSAKSAEEKNNWMAALISLQY
RSTLERMLDVTMLQEEKEEQMRLPSSDLYRFAEPDSEENIVFEENMQPKSGIPIIKAGTV
IKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLLIERFEIPEPEPTEADRIAMENG
DQPLSVELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDTDLLQRLEEFIGTVRGKAM
KKWVESITKIIQRKKMARDNGPGHNITFESSPPAVEWHISRPGHTETFDLLTLHPIEIAR
QLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVEAENLE
ERVAVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKILEEAHE
LSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLKRHGKELINFSKRRKVAE
ITGEIQQYQNQPYCLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRNPKPLPR
FPKKYSYPLKSPGVRPSNPRPGTMRHPTPLQQEPRKISYSRIPESETESTASAPNSPRTP
LTPPPASGASSTTDVCSVFDSDHSSPFHSSSDTIFLQVTLPHGPRSASVSSINLTKSTDE
MPIPPPVPPRRRPESAPAESSPSKIMSKHLDSPPAIPPRQPTSKVYSPRYSDRTSISDPP
ESPPLLPPREPVRTPDVFSSSPLHLQPPPLGKKSEHGNTFFPNSPSPFTPPPPQTPSPHG
TRRHLPSPPLTQQDVDLHSIPGPPVPPRQSTSQHIPKLPPKTYKREHTHPSMHRDGPPLL
ENAHSS
NT seq 4341 nt   +upstreamnt  +downstreamnt
atgtcattgtccaagagagttaactctgtgaagaagaggaaccactgtccttgttaccat
cagtaccaccttttgactaactgccagttcaaaagcaagcaaaccagcccagccaaaaca
gcaagacactctgaaagagacgtgagtggaagcatatggcaagcaggcaccatcttgact
actaaactctggtggaaacaacctaagagctctgtaccagagggcccagtcatcatgcct
tcctcccactggctctgcttccagcttaccttcctcaccctctgcagccatcatcccagg
gagaagcccctgtcaagaaggaatgtcaccatcatccccatcaccaccaaatttaacttt
gatgggcagataagccctaggaacagaattgcccaccatatcactggttcccaatacaac
tctacagccgtccagatgcaagtccatcctacacttgcatcaaatgaggatgctctccag
tatgttgaagagttaattctgcagcttttaagtatgctgtgccaagctcaaccccgaagc
gttttagatgttgaggatcgtgtacaaaaaagttttcctcatccaattgataagtgggca
atagctgatgctcagtctgctaatgaaaagaggaagcgaagaaatccattatctctccca
gtagaaaaaattcaccctttattaaaggaagttctagggtataaaattgaccaccaggtt
tctgtttacatagtagcagtattagaatacatttctgcagatattttaaagctggttgga
aattatgtgcggaatatacgacattatgaaattacaaagcaggacattaaagtagcaatg
tgtgctgacaaggtattgatggatatgttccatcaagatgtagaagatataaatatatta
tctttaactgatgaagaaccttccacttcaggagaacaaacatattacgacctggtaaag
gcatttatggctgaagttcgacaatatataagggaacttaatctcattattaaagttttt
agagaaccatttgtctccaattcaaaattattttcttctcacgatgtagaaaatatattt
agtcgtatagcagatgttcatgaactcagtgtgaaattattgggccatatagaagacact
gtagaaatgactgatgaaggtagtccccatccattagttggtagctgctttgaagactta
gcagaggagttggcatttgatccttatgaatcgtacgctcaagacatattacgacctggt
tttcatgaccactttcttagtcagttatccaagcctggggcagccctctatttgcagtca
ataggtgaaggtttcaaagaagctgttcagtatgttttacccaggctacttctggctcct
gtgtaccactgtctacattactttgaacttttaaagcagttagaagaaaagagtgaagac
caagaagacaaagaatgtttgaaacaagcaataacagctttgcttaaccttcagagcagt
atggaaagaatatgttccaagagtcttgcaaaacggagactgagcgaatctgcatgtcga
ttttatagccaacaaatgaaggggaaacaactagcaataaagaaaatgaatgagattcag
aagaatattgatggctgggaaggaaaagacattggacagtgctgcaatgagtttatcatg
gaaggaactctcacacgtgtaggtgccaaacacgagagacacatatttctctttgatggc
ctgatgatttgctgtaaatcaaatcatggtcagccaagacttcctggtgctagcaatgct
gagtatcgtctcaaagagaagttttttatgcgcaaggtacaaatcaatgataaagatgac
actaacgaatacaaacactcctttgaaataatcttaaaagatgaaaatagtgttatattt
tctgccaagtcagctgaggagaaaaacaactggatggcagcattgatatcattacaatac
cgcagtactctggaaaggatgctggatgtaacaatgttacaggaggagaaagaggagcag
atgaggcttccaagttctgacctttatagatttgcagaaccagactctgaagaaaatata
gtatttgaagaaaacatgcaacccaaatctggaattccaatcatcaaagctggaaccgtt
atcaaacttatagagagactcacctatcatatgtatgctgatcccaattttgttcggaca
tttcttacaacatatagatctttctgcaagcctcaagagctactgagtctcctaatagag
aggtttgaaatcccagagcctgagccaacggaagctgataggatagcaatggagaatgga
gatcaaccgctgagtgtggaactaaaacgatttagaaaagaatatatacagcctgtacaa
cttcgagtactaaatgtatgtcggcattgggtagaacaccacttctatgattttgaaaga
gatacagatcttttgcaacgactggaagaatttattggaacagtgaggggcaaagcaatg
aagaaatgggttgaatctatcactaaaatcatccagcggaaaaaaatggcaagagacaat
ggaccaggacataatattacttttgaaagttcacctcctgccgttgagtggcatataagc
agacccggacacacagagacttttgacctgctcaccttgcacccaatagaaattgctcga
cagcttactttacttgaatcagatctctaccgagctgtacagccatcagaattagttgga
agtgtgtggacaaaagaagacaaagaaattaattctcctaaccttctgaaaatgatccgc
cacacaaccaatcttactttgtggtttgaaaagtgtattgtagaagcagaaaacctagaa
gaaagagtagctgtggtgagtcgaataattgagattcttcaagtctttcaagaactgaac
aactttaacggtgtgcttgaagttgtcagcgccatgaactcatcacctgtttatagactg
gaccacacatttgagcaaattccaagtcgccaaaagaaaattttagaggaagctcatgaa
ctgagtgaagatcattataaaaaatatttggcaaaactcaggtctattaatccaccatgt
gtgcctttctttgggatttatttgacaaatatcttgaaaacagaagaaggcaatcctgag
gttttgaaaagacatggaaaagaacttataaacttcagtaaaagaagaaaagttgcagaa
ataacaggagagatacagcagtaccaaaatcaaccatattgtttgcgagtagaatctgat
atcaaaagattctttgaaaatttgaatccaatgggaaatagcatggaaaaagaattcaca
gattatcttttcaacaagtcactggaaattgaaccaagaaaccctaagcctctaccaaga
tttccaaaaaaatacagttatcccctcaagtctcctggtgttcgtccatcaaacccaaga
ccaggtaccatgagacaccccacaccactgcaacaggagccaaggaagattagttatagt
cggatccctgaaagtgagacagaaagtacagcatctgcacctaattctccaagaacaccg
ttaacacctccacctgcctcaggtgcttccagtaccaccgacgtgtgcagtgtgtttgat
tctgatcactcaagcccttttcactcaagcagcgataccatctttctccaagttacactg
ccccatggcccaagatctgcttctgtatcctcgataaatttaaccaagagcactgatgaa
atgcccattcccccacctgtgcccccaagaagaagaccagaatctgccccagcagaatct
tctccctccaagattatgtccaaacatttggatagtcctccagcaatccctcctcggcaa
cctacatcaaaagtctactcaccacgttactccgaccggacctccatatcagaccctcca
gaaagccctccccttttaccaccacgagaacccgtgaggacacctgatgttttctccagc
tcgccactacacctccagccaccccccttgggcaaaaaaagcgaacatggcaatactttc
ttcccaaacagcccctccccctttacaccgccacctcctcaaacaccttctcctcatggc
acaaggaggcatctgccatcaccaccattaacacaacaagatgtggacctgcattccatc
cctgggccacctgttcctccacgacaaagcacttctcaacacatcccaaaacttcctcca
aaaacttacaaaagggagcacacccacccatccatgcatagagatggaccacctttgttg
gagaatgcccattcctcctga

  All links  
Gene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (9)   
   Pfam (9)   
All databases (13)   

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