KEGG   Ursus americanus (American black bear): 123788966
Entry
123788966         CDS       T07931                                 
Symbol
SMO
Name
(RefSeq) protein smoothened isoform X1
  KO
K06226  smoothened
Organism
uar  Ursus americanus (American black bear)
Pathway
uar04340  Hedgehog signaling pathway
uar04360  Axon guidance
uar05200  Pathways in cancer
uar05205  Proteoglycans in cancer
uar05217  Basal cell carcinoma
Brite
KEGG Orthology (KO) [BR:uar00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04340 Hedgehog signaling pathway
    123788966 (SMO)
 09150 Organismal Systems
  09158 Development and regeneration
   04360 Axon guidance
    123788966 (SMO)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    123788966 (SMO)
   05205 Proteoglycans in cancer
    123788966 (SMO)
  09162 Cancer: specific types
   05217 Basal cell carcinoma
    123788966 (SMO)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors [BR:uar04030]
    123788966 (SMO)
G protein-coupled receptors [BR:uar04030]
 Frizzled / Smoothened family
  123788966 (SMO)
SSDB
Motif
Pfam: Frizzled Fz Dicty_CAR DUF7470
Other DBs
NCBI-GeneID: 123788966
NCBI-ProteinID: XP_045648624
UniProt: A0A452S5X4
Position
3:complement(22795250..22816212)
AA seq 787 aa
MAAARLARGPEILLLGLLLLLGGPSRGAALSGNATGPGPRSAGGSARRSAAVTGPPPLLS
HCGRAAPCEPLRYNVCLGSALPYGATSTLLAGDSDSQEEAHGKLVLWSGLRNAPRCWAVI
QPLLCAVYMPKCENDRVELPSRTLCQATRGPCAIVERERGWPDFLRCTPDRFPEGCPNEV
QNIKFNSSGQCEAPLVRTDNPKSWYEDVEGCGIQCQNPLFTEAEHQDMHSYIAAFGALTG
LCTLFTLATFVADWRNSNRYPAVILFYVNACFFVGSIGWLAQFMDGARREIVCRADGTMR
LGEPTSNETLSCVIIFVIVYYALMAGVVWFVVLTYAWHTSFKALGTTYQPLSGKTSYFHL
LTWSLPFVLTVAILAVAQVDGDSVSGICFVGYKNYRYRAGFVLAPIGLVLIVGGYFLIRG
VMTLFSIKSNHPGLLSEKAASKINETMLRLGIFGFLAFGFVLITFSCHFYDFFNQAEWER
SFRDYVLCQANVTIGLPTKKPIPDCEIKNRPSLLVEKINLFAMFGTGIAMSTWVWTKATL
LIWRRTWCRLTGQSDDEPKRIKKSKMIAKAFSKRRELLQNPGQELSFSMHTVSHEGPVAG
LAFDLNEPSADVSSAWAQHVTKMVARRGAILPQDVSVTPVATPVPPEEKANLWLVEAEIS
PELEKRLGRKKKRRKRKKEVCPLVPPPELHHPAPAPATSAVPRLPQLPRQKCLVAAGAWG
AGESCRQRAWTLVSNPFCPEPGPLRDPFLPSAAVPTAWAQGCRQGLGPVHSRTNLMEAEL
MDADSDF
NT seq 2364 nt   +upstreamnt  +downstreamnt
atggccgctgcccgcctcgcacgggggccggagatcctgctcctggggctgctgctgctg
ctggggggcccgagccggggggcggccttgagcgggaacgcgactgggcctgggccgcgg
agcgcgggcgggagcgcgaggaggagcgcggccgtgaccggccctccgccgctgctgagc
cactgcggccgcgcagccccctgcgagccgctgcgctacaacgtgtgcctgggctcggcg
ctgccctacggggccacctccacgctgctggccggggactcggactcccaggaagaagcg
cacggcaagctcgtgctctggtcgggcctccggaacgccccccgctgctgggcagtgatc
cagcccctgctgtgtgctgtgtacatgcccaaatgcgagaatgaccgggtggagctgccc
agccgcaccctctgccaggctacccgaggcccctgtgccatcgtggagagggagcgcggc
tggcctgacttcctgcgctgtacccctgaccgcttccccgagggctgcccgaatgaggtg
cagaacatcaagttcaacagttcgggccagtgcgaggctcccttggttcggactgacaac
cccaagagctggtatgaggacgtggagggatgtgggatccagtgtcagaacccgctgttc
accgaggccgagcaccaggacatgcacagctacatcgcagccttcggggcgctcacgggc
ctctgcacgctcttcaccctggccacgtttgtggctgactggcggaattcgaatcgctac
cctgctgtcattctcttctatgtcaatgcgtgtttctttgtggggagcattggctggctg
gcccagttcatggatggcgcccgccgggagatcgtctgccgtgcagatggcaccatgagg
cttggggagcccacctccaatgagaccctgtcctgcgtcatcatctttgtcatcgtgtac
tacgccctgatggctggtgtcgtctggtttgtggtcctcacctacgcctggcacacctcc
ttcaaagccctgggcaccacctaccagcctctctccggcaagacctcctacttccacctg
ctcacatggtcactcccctttgtcctcaccgtggcaatccttgccgtggcccaggtggat
ggggactccgtgagcggcatctgttttgttggctacaagaactaccgataccgcgctggc
ttcgtcctggccccgatcggcctggtgctcattgtgggaggttacttcctcatccgagga
gtcatgactctgttttccatcaagagcaaccatcccgggttgctgagtgagaaggctgcc
agcaagatcaatgagaccatgctgcgcctgggcatttttggcttcctggcctttggcttt
gtgctcatcaccttcagctgccatttctacgacttcttcaaccaggctgagtgggagcgc
agcttccgggactatgtgttgtgccaggccaatgtgaccatcgggctgcccaccaagaag
cccatccccgactgtgaaatcaagaatcgccctagcctcctggtggagaagatcaacctg
ttcgccatgtttggaaccggcattgccatgagcacctgggtctggaccaaggccacgctg
ctcatctggaggcgcacctggtgcaggttgactgggcagagtgatgatgagcccaaacgc
atcaagaagagcaaaatgatcgccaaggccttctccaagcggcgtgagctgctgcagaac
ccaggccaggaactctccttcagcatgcacactgtctcccacgaggggcctgtggcgggt
ttggcctttgacctcaatgagccctctgccgacgtgtcctctgcctgggcccagcatgtc
acgaagatggtggctcggcgaggagccatactgccccaggatgtgtctgtcacccctgtg
gcaactccagtgcccccagaggaaaaagccaacctgtggttggttgaggcagagatctcc
ccagagctggagaagcgcctgggccggaagaagaagcggaggaagaggaagaaggaggtg
tgcccactggtgccgccccctgagcttcaccaccccgcccctgcccctgcgaccagcgca
gttcctcgcctgcctcagctgcccaggcagaagtgtttggtggccgcaggtgcctgggga
gccggggaatcctgccgacagagagcctggaccctggtctccaaccctttctgcccagag
cccggtcccctgcgggacccatttctgcccagtgccgcagttcccacggcctgggctcag
ggctgccgccaggggctggggcccgttcactcccgcaccaacctgatggaggccgagctc
atggacgcagattcagacttctga

  All links  
Gene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (4)   
   UniProt (1)   
   RefSeq(pep) (3)   
DNA sequence (4)   
   RefSeq(nuc) (4)   
Protein domain (4)   
   Pfam (4)   
All databases (14)   

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