ID A0A7K0CG88_9ACTN Unreviewed; 370 AA.
AC A0A7K0CG88;
DT 07-APR-2021, integrated into UniProtKB/TrEMBL.
DT 07-APR-2021, sequence version 1.
DT 28-JAN-2026, entry version 12.
DE SubName: Full=3-amino-4-hydroxybenzoic acid synthase {ECO:0000313|EMBL:MQY12491.1};
DE EC=4.1.99.20 {ECO:0000313|EMBL:MQY12491.1};
GN Name=griH_2 {ECO:0000313|EMBL:MQY12491.1};
GN ORFNames=SRB5_26250 {ECO:0000313|EMBL:MQY12491.1};
OS Streptomyces smaragdinus.
OC Bacteria; Bacillati; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=2585196 {ECO:0000313|EMBL:MQY12491.1, ECO:0000313|Proteomes:UP000466345};
RN [1] {ECO:0000313|EMBL:MQY12491.1, ECO:0000313|Proteomes:UP000466345}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RB5 {ECO:0000313|EMBL:MQY12491.1,
RC ECO:0000313|Proteomes:UP000466345};
RA Schwitalla J., Benndorf R., Martin K., De Beer W., Kaster A.-K.,
RA Vollmers J., Poulsen M., Beemelmanns C.;
RT "Streptomyces smaragdinus sp. nov. and Streptomyces fabii sp. nov.,
RT isolated from the gut of fungus growing-termite Macrotermes natalensis.";
RL Submitted (OCT-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:MQY12491.1}.
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DR EMBL; WEGJ01000007; MQY12491.1; -; Genomic_DNA.
DR RefSeq; WP_153452109.1; NZ_WEGJ01000007.1.
DR AlphaFoldDB; A0A7K0CG88; -.
DR OrthoDB; 2043123at2; -.
DR Proteomes; UP000466345; Unassembled WGS sequence.
DR GO; GO:0003856; F:3-dehydroquinate synthase activity; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR GO; GO:0008652; P:amino acid biosynthetic process; IEA:UniProtKB-KW.
DR GO; GO:0009073; P:aromatic amino acid family biosynthetic process; IEA:UniProtKB-KW.
DR InterPro; IPR002812; DHQS.
DR InterPro; IPR030960; DHQS/DOIS_N.
DR InterPro; IPR056179; DHQS_C.
DR NCBIfam; NF002625; PRK02290.1-3; 1.
DR PANTHER; PTHR33563; -; 1.
DR PANTHER; PTHR33563:SF1; 3-DEHYDROQUINATE SYNTHASE; 1.
DR Pfam; PF01959; DHQS; 1.
DR Pfam; PF26558; DHQS_2nd; 1.
PE 4: Predicted;
KW Amino-acid biosynthesis {ECO:0000256|ARBA:ARBA00022605};
KW Aromatic amino acid biosynthesis {ECO:0000256|ARBA:ARBA00023141};
KW Lyase {ECO:0000313|EMBL:MQY12491.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000466345}.
FT DOMAIN 5..181
FT /note="3-dehydroquinate synthase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01959"
FT DOMAIN 195..370
FT /note="3-dehydroquinate synthase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF26558"
SQ SEQUENCE 370 AA; 38995 MW; 987E75B54673D9F4 CRC64;
MTDEKLCWLD IRTAGPATGA VVEEAVHQRV DGLVTDDPAT LAGLPPTVRK VLVFRGEPGD
GVDFGAADIV VLPGPTAARA ELTAAYPGVE FGRFVEIVDA DTLEEACRSA RTERWSVLDF
RDPTKIPLEI VIAAAAGADG TIVTLASGVE EAEIIFGVLE LGSDGVLMPA RAVGDATALR
RAALGGGGEL TLVELEVTGS THIGMGERAC VDTCAYLGQD EGILVGSHSK GMMLCVSETH
PLPYMPTRPF RVNAGAIHSY TLAGAGRTQY LSELRSGAKV LAVDIKGRTR LVGVGRVKIE
SRPLISIDAV APNGRTVNLI LQDDWHVRVL GPGGTVLNST ELRPGDKVLG YLPTADRHVG
YPIGEFCLEQ
//
