ID A0A8R7PC26_TRIUA Unreviewed; 1547 AA.
AC A0A8R7PC26;
DT 12-OCT-2022, integrated into UniProtKB/TrEMBL.
DT 12-OCT-2022, sequence version 1.
DT 18-JUN-2025, entry version 14.
DE RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
OS Triticum urartu (Red wild einkorn) (Crithodium urartu).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4572 {ECO:0000313|EnsemblPlants:TuG1812G0200001711.01.T02, ECO:0000313|Proteomes:UP000015106};
RN [1] {ECO:0000313|Proteomes:UP000015106}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=cv. G1812 {ECO:0000313|Proteomes:UP000015106};
RX PubMed=23535596; DOI=10.1038/nature11997;
RA Ling H.Q., Zhao S., Liu D., Wang J., Sun H., Zhang C., Fan H., Li D.,
RA Dong L., Tao Y., Gao C., Wu H., Li Y., Cui Y., Guo X., Zheng S., Wang B.,
RA Yu K., Liang Q., Yang W., Lou X., Chen J., Feng M., Jian J., Zhang X.,
RA Luo G., Jiang Y., Liu J., Wang Z., Sha Y., Zhang B., Wu H., Tang D.,
RA Shen Q., Xue P., Zou S., Wang X., Liu X., Wang F., Yang Y., An X., Dong Z.,
RA Zhang K., Zhang X., Luo M.C., Dvorak J., Tong Y., Wang J., Yang H., Li Z.,
RA Wang D., Zhang A., Wang J.;
RT "Draft genome of the wheat A-genome progenitor Triticum urartu.";
RL Nature 496:87-90(2013).
RN [2] {ECO:0000313|EnsemblPlants:TuG1812G0200001711.01.T02}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. G1812
RC {ECO:0000313|EnsemblPlants:TuG1812G0200001711.01.T02};
RA Ling H., Ma B., Shi X., Liu H., Dong L., Sun H., Cao Y., Gao Q., Zheng S.,
RA Li Y., Yu Y., Du H., Qi M., Li Y., Yu H., Cui Y., Wang N., Chen C., Wu H.,
RA Zhao Y., Zhang J., Li Y., Zhou W., Zhang B., Hu W., Eijk M., Tang J.,
RA Witsenboer H., Zhao S., Li Z., Zhang A., Wang D., Liang C.;
RT "The Triticum urartu genome reveals the dynamic nature of wheat genome
RT evolution.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblPlants:TuG1812G0200001711.01.T02}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (JUN-2022) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + phosphate + H(+); Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC Evidence={ECO:0000256|ARBA:ARBA00047984};
CC -!- SIMILARITY: Belongs to the DEAD box helicase family. DEAH subfamily.
CC {ECO:0000256|ARBA:ARBA00008792}.
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DR EnsemblPlants; TuG1812G0200001711.01.T01; TuG1812G0200001711.01.T01; TuG1812G0200001711.01.
DR EnsemblPlants; TuG1812G0200001711.01.T02; TuG1812G0200001711.01.T02; TuG1812G0200001711.01.
DR EnsemblPlants; TuG1812G0200001711.01.T03; TuG1812G0200001711.01.T03; TuG1812G0200001711.01.
DR EnsemblPlants; TuG1812G0200001711.01.T04; TuG1812G0200001711.01.T04; TuG1812G0200001711.01.
DR Gramene; TuG1812G0200001711.01.T01; TuG1812G0200001711.01.T01; TuG1812G0200001711.01.
DR Gramene; TuG1812G0200001711.01.T02; TuG1812G0200001711.01.T02; TuG1812G0200001711.01.
DR Gramene; TuG1812G0200001711.01.T03; TuG1812G0200001711.01.T03; TuG1812G0200001711.01.
DR Gramene; TuG1812G0200001711.01.T04; TuG1812G0200001711.01.T04; TuG1812G0200001711.01.
DR Proteomes; UP000015106; Chromosome 2.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:TreeGrafter.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:TreeGrafter.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR CDD; cd20335; BRcat_RBR; 1.
DR CDD; cd17917; DEXHc_RHA-like; 1.
DR CDD; cd22585; Rcat_RBR_DEAH12-like; 1.
DR CDD; cd18791; SF2_C_RHA; 1.
DR FunFam; 1.20.120.1750:FF:000020; ATP-dependent RNA helicase DEAH12 chloroplastic; 1.
DR FunFam; 3.30.40.10:FF:000485; ATP-dependent RNA helicase DEAH12 chloroplastic; 1.
DR FunFam; 3.40.50.300:FF:001279; ATP-dependent RNA helicase DEAH12 chloroplastic; 1.
DR FunFam; 3.40.50.300:FF:002114; ATP-dependent RNA helicase DEAH12 chloroplastic; 1.
DR FunFam; 1.20.120.1080:FF:000033; RBR-type E3 ubiquitin transferase; 1.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 1.20.120.1750; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR002464; DNA/RNA_helicase_DEAH_CS.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C-like.
DR InterPro; IPR002867; IBR_dom.
DR InterPro; IPR056245; KH_DEAH11/12.
DR InterPro; IPR056246; KH_DEAH11/12_1st.
DR InterPro; IPR056247; KH_DEAH11/12_2nd.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR056248; RBD_DEAH11/12.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR056244; RRM_DEAH11/12.
DR InterPro; IPR044066; TRIAD_supradom.
DR InterPro; IPR013087; Znf_C2H2_type.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR PANTHER; PTHR18934:SF81; ATP-DEPENDENT RNA HELICASE DEAH11, CHLOROPLASTIC-RELATED; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF01485; IBR; 2.
DR Pfam; PF24471; KH_DEAH11; 1.
DR Pfam; PF24638; KH_DEAH11_1st; 1.
DR Pfam; PF24641; KH_DEAH11_2nd; 1.
DR Pfam; PF07717; OB_NTP_bind; 1.
DR Pfam; PF24475; RBD_DEAH11; 1.
DR Pfam; PF24637; RRM_DEAH11; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00847; HA2; 1.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00647; IBR; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF57850; RING/U-box; 3.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR PROSITE; PS00690; DEAH_ATP_HELICASE; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS51873; TRIAD; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000015106};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 64..228
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 267..433
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT DOMAIN 1331..1539
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS51873"
FT DOMAIN 1335..1377
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
SQ SEQUENCE 1547 AA; 174081 MW; CB598C41B4D4401D CRC64;
MSSIRRAMLH GTDEEEEVEE EGVDVFGIGE GKDVDFARLH MMMLRECRRL NEGLPIYAYR
RKILNHIFNN QVMTLIGETG SGKSTQLVQF LADSGLAANG SIVCTQPRKI AATSLARRVD
EESNGCYKDN FVLSYSTFLN SQDLNSKIIF CTDSCLLHHC MNDTGLDGIS YIIVDEAHER
SLNTDLLLAL IKKKLLDRLD LHLIIMSATA DADKLADYFY GCQTFHVKGR NFPVEINYVP
DVSVEGSSNA VPNSMCDACA TASYVNDVVR MVSIIHKNEE EGAVLAFLTS QLEVEWACEN
FSDASAVVLP MHGKLSHVEQ SRVFKSYPGK RKIIFCTNMA ETSLTIKEVK YVVDSGLAKE
SRFVPSSGLN VLKVNWISQS SANQRAGRAG RTGAGKCYRL YSEADFSMMD VHQEPEIRKV
HLGTAVLRIL ALGVKDARKF EFVDAPNPEA ISMAVKNLEQ LGAVKHRLNC FELTDTGRYL
VKLGIEPRLG KIMLDCFDVG LRKEGVVLAA VMANSSNIFC RVGTDEEKHK ADLQKVRLCH
RDGDLFTLLA VYKKWEDGHD NRNMWCWQNS INAKTMRRCQ ETISELENCL KHELNIIVPS
YWRWNPEAPT VHDKDLKRII LSSLTGNLAM FLGHERFGYQ VISTGQVVNL HPSSSLLNYG
IKPEWVVFTE ILSVPNQYLV CVTAVDHDAL YTIHPVSFIK QLEEQKLQIK VISGLGTNLL
RRFCGKYGQN QQKIISRLKE DCRDDRITVE INFQNNEVVL FATEQNMEKV FCTVNSALEC
EGKILRNECL ERNLFPGRPG SSPIALFGSG AEIKHLELGG RYLTVEVLHQ NAHDIDDKEL
IFLVDSIGSG IANFHKSTGS FRIASDGIKW GKFTFLKPEN AEDAVSKLNG IEFNGSSLKL
VPVCTFDNRG LPFPAVRAKL CWPRRHSSGR ALITCASGEA EFVVNDCFAL GIGGRYIKCR
VSTKYENCVF AEGIPMHVTE PELYDAFRST TARRILNIRL LRVKGNAIAS PSVSTCEEEL
VREISPFMSN KSFPGQNFRV EVFPPEENDS LTRATITFDG SLHREAARAL DHLEGHFLPC
CQPWQIIQCN HVFHSTLSCP VRVYNVISQE VASLLESFQS QKGVSYNFEK TENGIFRLKL
TANATKTIAD LRRPLEILMK GKTINHPDLT LSAVQLLLSR DGVAHLKSIE QETGTYIMYD
RQSLNIKVFG HQDQMAAAEV KLVHALRQLL EKKPLEIYLR GHNLPPDLMK KTVENFGVDL
EGFNKEMPEI KVELHQHRHL LKVWGSKEDK RRVERMISEL ASFKHSSLVQ LASENVGGKE
DNQRVDYDEP SEDACPICLC EIEDPFRLES CGHMFCLACL VDQCESAMKS HDGFPICCLK
TGCKEPLLVI DLKHLLSNEK LEDLFRASLR AFVASRAGMY RFCPTPDCQS IYQVAAPDAE
TKPFSCGACY VEICTKCHFE YHPFISCEAY KEYKEDPDST LLEWRKGKAN VKSCPSCGYT
IEKSDGCNHV ECRCGSHICW VCLENFRSSE ECYGHLRSVH QSFVDIV
//
