+F Repair protein KO
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DNA Repair and Recombination Proteins - Arthrobacter sp. LS16
%
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D AFL94_01295 cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D AFL94_15595 deoxyribodipyrimidine photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E AFL94_02605 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E AFL94_00540 Fe-S cluster assembly protein HesB K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E AFL94_12840 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D AFL94_05325 DNA mismatch repair protein MutT K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D AFL94_05520 hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D AFL94_11725 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D AFL94_06530 ADP-ribose pyrophosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D AFL94_02690 pyrimidine (deoxy)nucleoside triphosphate pyrophosphohydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D AFL94_03340 DNA mismatch repair protein MutT K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D AFL94_10640 deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
#
AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D AFL94_01295 cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D AFL94_15595 deoxyribodipyrimidine photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D AFL94_13990 DNA repair protein K03919 alkB; DNA oxidative demethylase [EC:1.14.11.33]
C BER (base exicision repair)
D DNA glycosylases
E AFL94_02605 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E AFL94_00540 Fe-S cluster assembly protein HesB K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E AFL94_02860 3-methyladenine DNA glycosylase K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E AFL94_07425 formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E AFL94_01880 DNA glycosylase K05522 nei; endonuclease VIII [EC:3.2.2.- 4.2.99.18]
E AFL94_09790 formamidopyrimidine-DNA glycosylase K05522 nei; endonuclease VIII [EC:3.2.2.- 4.2.99.18]
E AFL94_12840 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E AFL94_00920 exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E AFL94_03345 exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D RecJ
D DNA ligase
E AFL94_04015 NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E AFL94_10235 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E AFL94_10060 excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
E AFL94_10160 excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
E AFL94_10045 excinuclease ABC subunit C K03703 uvrC; excinuclease ABC subunit C
E AFL94_02710 ATP-dependent DNA helicase PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E AFL94_11215 ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E AFL94_11230 DNA helicase UvrD K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E AFL94_10235 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E AFL94_04015 NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F AFL94_12150 DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F AFL94_12145 DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F AFL94_11960 DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F AFL94_08595 DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F AFL94_03850 transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D Molecular matchmaker
D Strand discrimination factor
D DNA exonucleases
E AFL94_11690 exodeoxyribonuclease VII large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E AFL94_11695 exodeoxyribonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E AFL94_10835 DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E AFL94_00010 DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E AFL94_08515 DNA polymerase III subunit delta K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E AFL94_02395 DNA polymerase III subunit delta' K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E AFL94_06175 exonuclease K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E AFL94_06370 exonuclease K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E AFL94_11245 DNA polymerase III subunit epsilon K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
D DNA ligase
E AFL94_04015 NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E AFL94_02710 ATP-dependent DNA helicase PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E AFL94_11215 ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E AFL94_11230 DNA helicase UvrD K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E AFL94_17415 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E AFL94_08935 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E AFL94_15670 hypothetical protein K07458 vsr; DNA mismatch endonuclease, patch repair protein [EC:3.1.-.-]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E AFL94_05220 recombinase RecA K03553 recA; recombination protein RecA
E AFL94_09060 ATP-dependent DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E AFL94_09055 ATP-dependent DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E AFL94_09065 crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E AFL94_08580 primosomal protein PriA K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E AFL94_06195 hypothetical protein K03546 sbcC; DNA repair protein SbcC/Rad50
E AFL94_06390 hypothetical protein K03546 sbcC; DNA repair protein SbcC/Rad50
E AFL94_06190 exonuclease SbcD K03547 sbcD; DNA repair protein SbcD/Mre11
E AFL94_06385 exonuclease SbcD K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E AFL94_05220 recombinase RecA K03553 recA; recombination protein RecA
E AFL94_00555 DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms
E AFL94_00015 recombinase RecF K03629 recF; DNA replication and repair protein RecF
E AFL94_07320 ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E AFL94_11070 hypothetical protein K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E AFL94_08430 DNA recombination protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
E AFL94_05500 DNA recombination protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
E AFL94_09060 ATP-dependent DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E AFL94_09055 ATP-dependent DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E AFL94_09065 crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
D Other HR factor
D Archaeal homologous recombinant proteins
E AFL94_06195 hypothetical protein K03546 sbcC; DNA repair protein SbcC/Rad50
E AFL94_06390 hypothetical protein K03546 sbcC; DNA repair protein SbcC/Rad50
E AFL94_06190 exonuclease SbcD K03547 sbcD; DNA repair protein SbcD/Mre11
E AFL94_06385 exonuclease SbcD K03547 sbcD; DNA repair protein SbcD/Mre11
E AFL94_13170 ATPase K06915 herA; DNA double-strand break repair helicase HerA and related ATPase
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
E AFL94_15555 hypothetical protein K10979 ku; DNA end-binding protein Ku
E AFL94_15560 ATP-dependent DNA ligase K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1]
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F AFL94_10675 DNA topoisomerase IV subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F AFL94_00030 DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F AFL94_10705 DNA topoisomerase IV subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F AFL94_00025 DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F AFL94_12760 DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
F AFL94_14530 hypothetical protein K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F AFL94_13220 integration host factor K03530 hupB; DNA-binding protein HU-beta
F AFL94_13225 integration host factor K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F AFL94_08430 DNA recombination protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
F AFL94_04015 NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
E Supressor
F AFL94_02320 ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F AFL94_10060 excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
F AFL94_10160 excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D AFL94_10940 DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D AFL94_01795 DNA polymerase K03502 umuC; DNA polymerase V
D AFL94_01790 DNA polymerase subunit UmuD K03503 umuD; DNA polymerase V [EC:3.4.21.-]
C Other SOS response factors
D AFL94_05220 recombinase RecA K03553 recA; recombination protein RecA
D AFL94_05260 LexA family transcriptional regulator K01356 lexA; repressor LexA [EC:3.4.21.88]
D AFL94_05500 DNA recombination protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D AFL94_09225 DNA polymerase III subunit alpha K14162 dnaE2; error-prone DNA polymerase [EC:2.7.7.7]
D AFL94_17415 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D AFL94_08935 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D AFL94_05225 hypothetical protein K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D AFL94_05255 ATP-dependent helicase K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
D AFL94_01885 DEAD/DEAH box helicase K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
C Modulation of nucleotide pools
D AFL94_05325 DNA mismatch repair protein MutT K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D AFL94_05520 hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D AFL94_11725 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D AFL94_06530 ADP-ribose pyrophosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D AFL94_02690 pyrimidine (deoxy)nucleoside triphosphate pyrophosphohydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D AFL94_03340 DNA mismatch repair protein MutT K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D AFL94_12265 NUDIX hydrolase K23258 mutT1; 8-oxo-(d)GTP phosphatase [EC:3.6.1.69]
D AFL94_05510 ADP-ribose pyrophosphatase K01554 K01554; 8-oxo-dGDP phosphatase [EC:3.6.1.58]
D AFL94_10640 deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D AFL94_09330 ribonucleotide-diphosphate reductase subunit alpha K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D AFL94_09325 ribonucleotide-diphosphate reductase subunit beta K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024