+F Repair protein KO
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DNA Repair and Recombination Proteins - Borrelia afzelii (FLI)
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
C BER (base exicision repair)
D DNA glycosylases
E BAPKO_0053 ung; uracil DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E BAPKO_0442 mag; 3-methyladenine DNA glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E BAPKO_0791 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
C BER (base exicision repair)
D DNA glycosylases
E BAPKO_0053 ung; uracil DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E BAPKO_0012 hypothetical protein K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E BAPKO_0442 mag; 3-methyladenine DNA glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E BAPKO_0791 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E BAPKO_0559 exoA; exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D RecJ
E BAPKO_0264 recJ; single-stranded-DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E BAPKO_0581 lig; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E BAPKO_0577 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E BAPKO_0890 uvrA; excinuclease ABC, subunit A K03701 uvrA; excinuclease ABC subunit A
E BAPKO_0889 uvrB; excinuclease ABC, subunit B K03702 uvrB; excinuclease ABC subunit B
E BAPKO_0481 uvrC; excinuclease ABC, subunit C K03703 uvrC; excinuclease ABC subunit C
E BAPKO_0353 uvrD; DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E BAPKO_0640 rep; rep helicase, single-stranded DNA-dependent ATPase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E BAPKO_0577 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E BAPKO_0581 lig; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F BAPKO_0404 rpoB; DNA-directed RNA polymerase K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F BAPKO_0403 rpoC; DNA-directed RNA polymerase K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F BAPKO_0530 rpoA; DNA-directed RNA polymerase K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F BAPKO_0663 mfd; transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E BAPKO_0850 mutS; DNA mismatch repair protein K03555 mutS; DNA mismatch repair protein MutS
E BAPKO_0099 DNA mismatch repair protein, putative K07456 mutS2; DNA mismatch repair protein MutS2
D Molecular matchmaker
E BAPKO_0218 mutL; DNA mismatch repair protein K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
D DNA exonucleases
D DNA polymerase III holoenzyme
E BAPKO_0610 dnaE; DNA polymerase III, subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E BAPKO_0460 dnaN; DNA polymerase III, subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E BAPKO_0478 conserved hypothetical protein K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E BAPKO_0490 dnaX; DNA polymerase III, subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
E BAPKO_0813 hypothetical protein K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E BAPKO_0581 lig; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E BAPKO_0353 uvrD; DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E BAPKO_0640 rep; rep helicase, single-stranded DNA-dependent ATPase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E BAPKO_0115 ssb; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E BAPKO_0676 recB; exodeoxyribonuclease V, beta chain K03582 recB; exodeoxyribonuclease V beta subunit [EC:3.1.11.5]
E BAPKO_0677 recC; exodeoxyribonuclease V, gamma chain K03583 recC; exodeoxyribonuclease V gamma subunit [EC:3.1.11.5]
E BAPKO_0675 recD; exodeoxyribonuclease V, alpha chain K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E BAPKO_0133 recA; recA protein K03553 recA; recombination protein RecA
E BAPKO_0022 ruvA; Holliday junction DNA helicase K03550 ruvA; holliday junction DNA helicase RuvA
E BAPKO_0021 ruvB; Holliday junction DNA helicase K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E BAPKO_0013 priA; primosomal protein N K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E BAPKO_0883 sbcC; exonuclease SbcC K03546 sbcC; DNA repair protein SbcC/Rad50
E BAPKO_0882 sbcD; exonuclease SbcD K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E BAPKO_0133 recA; recA protein K03553 recA; recombination protein RecA
E BAPKO_0612 recG; DNA recombinase K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E BAPKO_0264 recJ; single-stranded-DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E BAPKO_0022 ruvA; Holliday junction DNA helicase K03550 ruvA; holliday junction DNA helicase RuvA
E BAPKO_0021 ruvB; Holliday junction DNA helicase K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
D AddAB pathway proteins
D Other HR factor
D Archaeal homologous recombinant proteins
E BAPKO_0883 sbcC; exonuclease SbcC K03546 sbcC; DNA repair protein SbcC/Rad50
E BAPKO_0882 sbcD; exonuclease SbcD K03547 sbcD; DNA repair protein SbcD/Mre11
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F BAPKO_0457 gyrA; DNA gyrase, subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F BAPKO_0458 gyrB; DNA gyrase, subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F BAPKO_0881 topA; DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F BAPKO_0264 recJ; single-stranded-DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F BAPKO_0581 lig; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
F BAPKO_0241 hbb; hbbU protein K05788 ihfB; integration host factor subunit beta
E Supressor
F BAPKO_0890 uvrA; excinuclease ABC, subunit A K03701 uvrA; excinuclease ABC subunit A
F BAPKO_0889 uvrB; excinuclease ABC, subunit B K03702 uvrB; excinuclease ABC subunit B
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C Other SOS response factors
D BAPKO_0133 recA; recA protein K03553 recA; recombination protein RecA
D BAPKO_0115 ssb; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
C Modulation of nucleotide pools
C Others
D BAPKO_0657 hypothetical protein K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024