+D	Messenger RNA Biogenesis	KO
#<h2><a href="/kegg/brite.html"><img src="/Fig/bget/kegg3.gif" align="middle" border=0></a>&nbsp; Prokaryotic Defense System - Bifidobacterium animalis subsp. lactis AD011</h2>
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A<b>CRISPR-Cas system</b>
B  Universal Cas proteins
C    BLA_0514 cas1; CRISPR-associated protein Cas1	K15342 cas1; CRISP-associated protein Cas1 
B  Type I CRISPR-Cas system
C    Type I signiture cas proteins
D      BLA_0512 CRISPR-associated HD domain protein	K07012 cas3; CRISPR-associated endonuclease/helicase Cas3 [EC:3.1.-.- 5.6.2.4] 
C    Subtype I-A factors
C    Subtype I-B factors
C    Subtype I-C factors
C    Subtype I-D factors
C    Subtype I-E factors
C    Subtype I-F factors
C    Subtype I-U factors
D      BLA_0513 conserved hypothetical protein	K19131 csb1; CRISPR-associated protein Csb1 
B  Type II CRISPR-Cas system
C    Type II signiture cas proteins
C    Subtype II-A factors
C    Subtype II-B factors
B  Type III CRISPR-Cas system
C    Type III signiture cas proteins
C    Subtype III-A factors
C    Subtype III-B factors
C    Subtype III-U factors
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A<b>Restriction and modification system (R-M system)</b>
B  Type I R-M system
B  Type II R-M system
C    Restriction endonucleases
C    DNA methyltransferases
D      BLA_0028 modification methylase SinI	K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] 
B  Type III R-M system
B  Type IV R-M system
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A<b>Toxin-antitoxin system (TA system)</b>
B  Type I TA system
C    Hok-Sok
C    SymE-SymR
C    Ldr-Rdl
C    TisB-IstR
C    Ibs-Sib
C    ShoB-OhsC
C    RalR-RalA
B  Type II TA system
C    MazF-MazE
D      BLA_0036 PemI-like protein	K07172 mazE; antitoxin MazE 
C    ChpB-ChpS
C    YhaV-PrlF
C    RelE/StbE-RelB/StbD
C    YafQ-dinJ
D      BLA_0035 conserved hypothetical protein	K19157 yafQ; mRNA interferase YafQ [EC:3.1.-.-] 
D      BLA_0698 DNA-damage-inducible protein J	K07473 dinJ; DNA-damage-inducible protein J 
D      BLA_0102 putative DNA-damage-inducible protein J	K07473 dinJ; DNA-damage-inducible protein J 
C    YoeB-YefM
C    HipA-HipB
C    HicA-HicB
C    YafO-YafN
C    Hha-TomB
C    PspC-PspB
C    CcdB-CcdA
C    ParE-ParD
C    Doc-Phd
D      BLA_1111 death-on-curing protein	K07341 doc; death on curing protein 
C    HigB-HigA
C    MqsR-MqsA
C    VapC-VapB
C    PezT-PezA
C    YobL-YobK
C    YokI-YokJ
C    YqcG-YqcF
C    YxiD-YxxD
C    FitB-FitA
C    BC_0920-BC_0921
C    Type II TA system related factors
D      BLA_0811 ftsZ; cell division protein FtsZ	K03531 ftsZ; cell division protein FtsZ 
D      BLA_0226 gltX; glutamyl-tRNA synthetase	K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] 
B  Type III TA system
C    AbiQ system
B  Type IV TA system
C    YeeV-YeeU
C    CptA-CptB
B  Type V TA system
C    GhoT-GhoS
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A<b>DNA phosphothiolation system</b>
B  Sulfur modification proteins
B  DNA phosphorothioation-dependent restriction proteins
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#Last updated: November 7, 2023