+E Ubiquitin system KO
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Ubiquitin System - Clavispora lusitaniae ATCC 42720
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AUbiquitins and ubiquitin-like proteins
B Ubiquitins
C CLUG_05273 ubiquitin K08770 UBC; ubiquitin C
C CLUG_03584 ubiquitin K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae
B Ubiquitin-like proteins (UBLs)
C CLUG_02776 hypothetical protein K12158 NEDD8; ubiquitin-like protein Nedd8
C CLUG_00079 hypothetical protein K08336 ATG12; ubiquitin-like protein ATG12
C CLUG_02706 hypothetical protein K12161 URM1; ubiquitin related modifier 1
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AUbiquitin-activating enzymes (E1)
B Ubiquitin activating enzyme
C CLUG_04188 ubiquitin-activating enzyme E1 1 K03178 UBE1; ubiquitin-activating enzyme E1 [EC:6.2.1.45]
B UBL-activating enzymes
C CLUG_00777 hypothetical protein K10684 UBLE1A; ubiquitin-like 1-activating enzyme E1 A [EC:6.2.1.45]
C CLUG_03541 hypothetical protein K10685 UBLE1B; ubiquitin-like 1-activating enzyme E1 B [EC:6.2.1.45]
C CLUG_01568 hypothetical protein K10686 UBA3; NEDD8-activating enzyme E1 [EC:6.2.1.64]
C CLUG_04264 hypothetical protein K04532 NAE1; NEDD8-activating enzyme E1 regulatory subunit
C CLUG_03530 hypothetical protein K11996 MOCS3; adenylyltransferase and sulfurtransferase [EC:2.7.7.80 2.8.1.11]
C CLUG_02477 hypothetical protein K08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7
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AUbiquitin-conjugating enzymes (E2)
B Ubiquitin-conjugating enzymes
C CLUG_00085 ubiquitin-conjugating enzyme E2-20 kDa K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
C CLUG_05769 ubiquitin-conjugating enzyme E2 4 K06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]
C CLUG_02199 hypothetical protein K04555 UBE2G2; ubiquitin-conjugating enzyme E2 G2 [EC:2.3.2.23]
C CLUG_00094 hypothetical protein K10576 UBE2H; ubiquitin-conjugating enzyme E2 H [EC:2.3.2.23]
C CLUG_00940 hypothetical protein K04554 UBE2J2; ubiquitin-conjugating enzyme E2 J2 [EC:2.3.2.23]
C CLUG_05206 hypothetical protein K04649 UBE2K; ubiquitin-conjugating enzyme (huntingtin interacting protein 2) [EC:2.3.2.23]
C CLUG_00847 hypothetical protein K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
C CLUG_05924 hypothetical protein K02207 UBE2R; ubiquitin-conjugating enzyme E2 R [EC:2.3.2.23]
C CLUG_00202 hypothetical protein K10688 UBE2W; ubiquitin-conjugating enzyme E2 W [EC:2.3.2.23 2.3.2.25]
C CLUG_01423 hypothetical protein K10689 PEX4; peroxin-4 [EC:2.3.2.23]
B UBL-conjugating enzymes
C CLUG_02841 hypothetical protein K10577 UBE2I; ubiquitin-conjugating enzyme E2 I
C CLUG_00974 hypothetical protein K08343 ATG3; ubiquitin-like-conjugating enzyme ATG3
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AUbiquitin ligases (E3)
B HECT type E3
C CLUG_01778 hypothetical protein K10589 UBE3C; ubiquitin-protein ligase E3 C [EC:2.3.2.26]
C CLUG_03509 hypothetical protein K20803 UBE3D; ubiquitin-protein ligase E3 D [EC:2.3.2.26]
C CLUG_05412 hypothetical protein K10590 TRIP12; E3 ubiquitin-protein ligase TRIP12 [EC:2.3.2.26]
C CLUG_02418 hypothetical protein K10591 NEDD4; E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26]
C CLUG_01571 hypothetical protein K10592 HUWE1; E3 ubiquitin-protein ligase HUWE1 [EC:2.3.2.26]
C CLUG_05496 hypothetical protein K12232 HECTD2; E3 ubiquitin-protein ligase HECTD2 [EC:2.3.2.26]
C HECT type E3 associated proteins
B U-box type E3
C CLUG_01961 hypothetical protein K10597 UBE4B; ubiquitin conjugation factor E4 B [EC:2.3.2.27]
C CLUG_02570 hypothetical protein K09561 STUB1; STIP1 homology and U-box containing protein 1 [EC:2.3.2.27]
C CLUG_00213 hypothetical protein K10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]
B Single Ring-finger type E3
C BRE1 proteins
D CLUG_03415 hypothetical protein K10696 BRE1; E3 ubiquitin-protein ligase BRE1 [EC:2.3.2.27]
C CBL proteins
C SINA (Seven in absentia) proteins
C Ligand of Numb proteins
C March proteins
C MDM2/MDM4 proteins
C NFX1 proteins
D CLUG_04633 hypothetical protein K12236 NFX1; transcriptional repressor NF-X1
C Pellino proteins
C Peripheral membrane proteins
D CLUG_05135 hypothetical protein K13346 PEX10; peroxin-10
D CLUG_05853 hypothetical protein K13345 PEX12; peroxin-12
D CLUG_05329 hypothetical protein K06664 PEX2; peroxin-2
C RBR proteins
D CLUG_04395 hypothetical protein K11968 ARIH1; ariadne-1 [EC:2.3.2.31]
D CLUG_01327 hypothetical protein K11971 RNF14; E3 ubiquitin-protein ligase RNF14 [EC:2.3.2.31]
C TRAF proteins
C TRIM/RBCC proteins
C UBR box proteins
D CLUG_04988 hypothetical protein K10625 UBR1; E3 ubiquitin-protein ligase UBR1 [EC:2.3.2.27]
D CLUG_04989 hypothetical protein K10625 UBR1; E3 ubiquitin-protein ligase UBR1 [EC:2.3.2.27]
D CLUG_05646 hypothetical protein K11979 UBR7; E3 ubiquitin-protein ligase UBR7 [EC:2.3.2.27]
C ATL proteins
C Other single Ring-finger type E3
D CLUG_00658 hypothetical protein K10632 BRAP; BRCA1-associated protein [EC:2.3.2.27]
D CLUG_03959 hypothetical protein K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]
D CLUG_03989 hypothetical protein K22377 LTN1; E3 ubiquitin-protein ligase listerin [EC:2.3.2.27]
D CLUG_03914 hypothetical protein K10627 RAD18; E3 ubiquitin-protein ligase RAD18 [EC:2.3.2.27]
D CLUG_00263 hypothetical protein K26979 RNF10; E3 ubiquitin-protein ligase RNF10 [EC:2.3.2.27]
D CLUG_05331 hypothetical protein K11984 SART1; U4/U6.U5 tri-snRNP-associated protein 1
D CLUG_05822 hypothetical protein K15710 SHPRH; E3 ubiquitin-protein ligase SHPRH [EC:5.6.2.- 2.3.2.27]
D CLUG_00621 hypothetical protein K10601 SYVN1; E3 ubiquitin-protein ligase synoviolin [EC:2.3.2.27]
D CLUG_05639 hypothetical protein K10601 SYVN1; E3 ubiquitin-protein ligase synoviolin [EC:2.3.2.27]
D CLUG_05726 hypothetical protein K22381 ZNF598; E3 ubiquitin-protein ligase ZNF598 [EC:2.3.2.27]
D CLUG_04265 hypothetical protein K16275 BAH; E3 ubiquitin-protein ligase BAH [EC:2.3.2.27]
D CLUG_01185 hypothetical protein K23788 TUL1; transmembrane E3 ubiquitin-protein ligase [EC:2.3.2.27]
D CLUG_00303 hypothetical protein K23787 DMA1_2; E3 ubiquitin-protein ligase DMA1/2 [EC:2.3.2.27]
B Atypical E3
C CLUG_01809 hypothetical protein K22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]
B UBL E3 ligases
C CLUG_04212 hypothetical protein K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
C CLUG_03626 hypothetical protein K04706 PIAS1; E3 SUMO-protein ligase PIAS1 [EC:2.3.2.-]
C CLUG_04307 hypothetical protein K22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]
C CLUG_01448 hypothetical protein K17822 DCUN1D1_2; DCN1-like protein 1/2
B Multi subunit Ring-finger type E3
C SCF complex
D Ring finger protein
E CLUG_04212 hypothetical protein K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
E CLUG_01999 hypothetical protein K03347 CUL1; cullin 1
D Adaptor protein
E CLUG_05863 hypothetical protein K03094 SKP1; S-phase kinase-associated protein 1
D Target recognizing subunit (F-box)
E CLUG_01441 hypothetical protein K10259 MET30; F-box and WD-40 domain protein MET30
E CLUG_00667 hypothetical protein K03361 CDC4; F-box and WD-40 domain protein CDC4
E CLUG_00729 hypothetical protein K10273 FBXL7; F-box and leucine-rich repeat protein 7
E CLUG_04360 hypothetical protein K10276 FBXL10_11; F-box and leucine-rich repeat protein 10/11 [EC:1.14.11.27]
E CLUG_01905 hypothetical protein K03360 GRR1; F-box and leucine-rich repeat protein GRR1
E CLUG_00595 hypothetical protein K15068 DIA2; protein DIA2
E CLUG_04421 hypothetical protein K10295 FBXO9; F-box protein 9
E CLUG_04919 hypothetical protein K15071 RCY1; recyclin-1
E CLUG_02099 hypothetical protein K15072 SAF1; SCF-associated factor 1
C Cul2 complex
D Ring finger protein
E CLUG_04212 hypothetical protein K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
D Adoptor protein
E CLUG_01416 hypothetical protein K03872 ELOC; elongin-C
D Target recognizing subunit
C Cul3 complex
D Ring finger protein
E CLUG_04212 hypothetical protein K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
E CLUG_05287 hypothetical protein K03869 CUL3; cullin 3
D Adoptor and target recognizing subunit (BTB)
E CLUG_04281 hypothetical protein K10520 ABTB1; ankyrin repeat and BTB/POZ domain-containing protein 1
C Cul4 complex
D Ring finger protein
E CLUG_04212 hypothetical protein K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
E CLUG_03733 hypothetical protein K10609 CUL4; cullin 4
D Adoptor protein
D Target recognizing subunit (DCAF)
E CLUG_02405 hypothetical protein K10570 ERCC8; DNA excision repair protein ERCC-8
E CLUG_00180 hypothetical protein K11805 DCAF7; DDB1- and CUL4-associated factor 7
E CLUG_02942 hypothetical protein K11806 DCAF13; DDB1- and CUL4-associated factor 13
E CLUG_04028 hypothetical protein K22382 WDR26; WD repeat-containing protein 26
E CLUG_05666 hypothetical protein K24755 WDR76; WD repeat-containing protein 76
C Cul5 complex
D Ring finger protein
D Cullin
D Adoptor protein
E CLUG_01416 hypothetical protein K03872 ELOC; elongin-C
D Target recognizing subunit
C Cul7 complex
D Ring finger protein
E CLUG_04212 hypothetical protein K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
D Adaptor protein
E CLUG_05863 hypothetical protein K03094 SKP1; S-phase kinase-associated protein 1
D Target recognizing subunit
C Cul8 complex
D Ring finger protein
E CLUG_04212 hypothetical protein K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
D Adaptor protein
D Target recognizing subunit
E CLUG_01040 hypothetical protein K26122 MMS22; E3 ubiquitin-protein ligase substrate receptor MMS22
C Cul9 complex
D Ring finger protein
E CLUG_04212 hypothetical protein K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
C APC/C
D Ring finger protein
E CLUG_02269 hypothetical protein K03358 APC11; anaphase-promoting complex subunit 11
D Cullin
E CLUG_01449 hypothetical protein K03349 APC2; anaphase-promoting complex subunit 2
D Target recognizing subunit
E CLUG_01884 hypothetical protein K03363 CDC20; cell division cycle 20, cofactor of APC complex
E CLUG_00784 hypothetical protein K03364 CDH1; cell division cycle 20-like protein 1, cofactor of APC complex
E CLUG_00383 hypothetical protein K12782 AMA1; meiosis-specific APC/C activator protein AMA1
D Other subunits
E CLUG_04474 hypothetical protein K03348 APC1; anaphase-promoting complex subunit 1
E CLUG_03947 hypothetical protein K03350 APC3; anaphase-promoting complex subunit 3
E CLUG_00726 hypothetical protein K03351 APC4; anaphase-promoting complex subunit 4
E CLUG_02097 hypothetical protein K03352 APC5; anaphase-promoting complex subunit 5
E CLUG_04505 hypothetical protein K03353 APC6; anaphase-promoting complex subunit 6
E CLUG_01007 hypothetical protein K03355 APC8; anaphase-promoting complex subunit 8
E CLUG_05874 hypothetical protein K03357 APC10; anaphase-promoting complex subunit 10
C BRCC complex
D CLUG_03761 hypothetical protein K04482 RAD51; DNA repair protein RAD51
D CLUG_00513 hypothetical protein K04482 RAD51; DNA repair protein RAD51
C KPC complex
C LUBAC complex
C CTLH complex
D CLUG_01415 hypothetical protein K23333 RMND5; E3 ubiquitin-protein transferase RMND5 [EC:2.3.2.27]
D CLUG_04768 hypothetical protein K18624 MAEA; macrophage erythroblast attacher
D CLUG_04199 hypothetical protein K23335 GID4; glucose-induced degradation protein 4
D CLUG_04368 hypothetical protein K23338 GID8; glucose-induced degradation protein 8
D CLUG_00191 hypothetical protein K23339 YPEL5; protein yippee-like 5
D CLUG_04028 hypothetical protein K22382 WDR26; WD repeat-containing protein 26
C ERAD complex
C LMBR1L-GP78-UBAC2 complex
C SLX5-SLX8 complex
D CLUG_03752 hypothetical protein K22645 SLX5; E3 ubiquitin-protein ligase complex SLX5-SLX8 subunit SLX5 [EC:2.3.2.27]
D CLUG_03785 hypothetical protein K22646 SLX8; E3 ubiquitin-protein ligase complex SLX5-SLX8 subunit SLX8 [EC:2.3.2.27]
C Multi subunit type E3 associated proteins
D CLUG_00680 hypothetical protein K17263 CAND1; cullin-associated NEDD8-dissociated protein 1
D CLUG_05861 hypothetical protein K24350 UBXN7; UBX domain-containing protein 7
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ADeubiquitinating enzyme (DUB)
B Ubiquitin-specific proteases (UBPs)
C UCH
D CLUG_03551 hypothetical protein K05609 UCHL3; ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]
C UBP/USP
D CLUG_03563 hypothetical protein K11835 USP4_11; ubiquitin carboxyl-terminal hydrolase 4/11 [EC:3.4.19.12]
D CLUG_00320 hypothetical protein K11836 USP5_13; ubiquitin carboxyl-terminal hydrolase 5/13 [EC:3.4.19.12]
D CLUG_02963 hypothetical protein K11838 USP7; ubiquitin carboxyl-terminal hydrolase 7 [EC:3.4.19.12]
D CLUG_05670 hypothetical protein K11839 USP8; ubiquitin carboxyl-terminal hydrolase 8 [EC:3.4.19.12]
D CLUG_00296 hypothetical protein K11841 USP10; ubiquitin carboxyl-terminal hydrolase 10 [EC:3.4.19.12]
D CLUG_02093 hypothetical protein K11843 USP14; ubiquitin carboxyl-terminal hydrolase 14 [EC:3.4.19.12]
D CLUG_02956 hypothetical protein K11366 USP22_27_51; ubiquitin carboxyl-terminal hydrolase 22/27/51 [EC:3.4.19.12]
D CLUG_03608 hypothetical protein K11849 USP25; ubiquitin carboxyl-terminal hydrolase 25 [EC:3.4.19.12]
D CLUG_04766 hypothetical protein K11870 UBP1; ubiquitin carboxyl-terminal hydrolase 1 [EC:3.4.19.12]
D CLUG_05455 hypothetical protein K11871 UBP7_11; ubiquitin carboxyl-terminal hydrolase 7/11 [EC:3.4.19.12]
D CLUG_04374 hypothetical protein K11872 UBP9_13; ubiquitin carboxyl-terminal hydrolase 9/13 [EC:3.4.19.12]
D CLUG_00192 hypothetical protein K11873 UBP10; ubiquitin carboxyl-terminal hydrolase 10 [EC:3.4.19.12]
D CLUG_03258 hypothetical protein K11874 UBP16; ubiquitin carboxyl-terminal hydrolase 16 [EC:3.4.19.12]
C OTU
D CLUG_00860 hypothetical protein K18342 OTUD6; OTU domain-containing protein 6 [EC:3.4.19.12]
C MJD
C MINDY
D CLUG_00484 hypothetical protein K01309 MINDY1_2; ubiquitin carboxyl-terminal hydrolase MINDY-1/2 [EC:3.4.19.12]
C JAMM
D CLUG_05679 hypothetical protein K03030 PSMD14; 26S proteasome regulatory subunit N11
C PPPDE
C ZUFSP
C BRISC complex
B UBL-specific proteases (ULPs)
C CLUG_02343 hypothetical protein K08592 SENP1; sentrin-specific protease 1 [EC:3.4.22.68]
C CLUG_00895 hypothetical protein K08596 SENP7; sentrin-specific protease 7 [EC:3.4.22.68]
C CLUG_01192 hypothetical protein K08597 SENP8; sentrin-specific protease 8 [EC:3.4.22.68]
C CLUG_03551 hypothetical protein K05609 UCHL3; ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]
C CLUG_01160 hypothetical protein K22762 DESI1; desumoylating isopeptidase 1 [EC:3.4.-.-]
C COP9 signalosome (CSN) complex
D CLUG_02723 hypothetical protein K12176 COPS2; COP9 signalosome complex subunit 2
D CLUG_00193 hypothetical protein K09613 COPS5; COP9 signalosome complex subunit 5 [EC:3.4.-.-]
D CLUG_01902 hypothetical protein K24364 CSN12; COP9 signalosome complex subunit 12
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: June 3, 2024