+F Repair protein KO
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DNA Repair and Recombination Proteins - Desulfofundulus kuznetsovii
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D Desku_0552 methylated-DNA/protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
C BER (base exicision repair)
D DNA glycosylases
E Desku_0652 3-methyladenine DNA glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E Desku_1665 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D Desku_2334 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D Desku_0552 methylated-DNA/protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
C BER (base exicision repair)
D DNA glycosylases
E Desku_3313 phage SPO1 DNA polymerase-related protein K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E Desku_0652 3-methyladenine DNA glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E Desku_0592 Formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E Desku_1665 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E Desku_1065 Xylose isomerase domain-containing protein TIM barrel K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
D RecJ
E Desku_2113 single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E Desku_1684 DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E Desku_0593 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E Desku_3307 UvrABC system protein A K03701 uvrA; excinuclease ABC subunit A
E Desku_3309 UvrABC system protein B K03702 uvrB; excinuclease ABC subunit B
E Desku_3306 UvrABC system protein C K03703 uvrC; excinuclease ABC subunit C
E Desku_1686 ATP-dependent DNA helicase PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E Desku_0593 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E Desku_1684 DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F Desku_3065 DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F Desku_3064 DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F Desku_3029 DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F Desku_1306 DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F Desku_0175 transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E Desku_1330 DNA mismatch repair protein mutS K03555 mutS; DNA mismatch repair protein MutS
E Desku_0657 MutS2 protein K07456 mutS2; DNA mismatch repair protein MutS2
D Molecular matchmaker
E Desku_1333 DNA mismatch repair protein mutL K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
D DNA exonucleases
E Desku_1935 Exodeoxyribonuclease 7 large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E Desku_1930 Exodeoxyribonuclease 7 small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E Desku_1657 DNA polymerase III, alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E Desku_0914 DNA polymerase III, beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E Desku_0002 DNA polymerase III, beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E Desku_2672 DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E Desku_0037 DNA polymerase III, delta prime subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E Desku_0025 DNA polymerase III, subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E Desku_1684 DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E Desku_1686 ATP-dependent DNA helicase PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E Desku_0903 single-strand binding protein K03111 ssb; single-strand DNA-binding protein
E Desku_3551 single-strand binding protein K03111 ssb; single-strand DNA-binding protein
E Desku_2479 DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
E Desku_1876 DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E Desku_0756 hypothetical protein K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E Desku_0728 helicase, RecD/TraA family K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E Desku_2381 Protein recA K03553 recA; recombination protein RecA
E Desku_0666 Holliday junction ATP-dependent DNA helicase ruvA K03550 ruvA; holliday junction DNA helicase RuvA
E Desku_0667 Holliday junction ATP-dependent DNA helicase ruvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E Desku_0665 Crossover junction endodeoxyribonuclease ruvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E Desku_1311 primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E Desku_0917 SMC domain protein K03546 sbcC; DNA repair protein SbcC/Rad50
E Desku_0689 SMC domain protein K03546 sbcC; DNA repair protein SbcC/Rad50
E Desku_0688 nuclease SbcCD, D subunit K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E Desku_2381 Protein recA K03553 recA; recombination protein RecA
E Desku_3155 DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms
E Desku_0003 DNA replication and repair protein recF K03629 recF; DNA replication and repair protein RecF
E Desku_1250 ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E Desku_2826 putative transcriptional regulator K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E Desku_2113 single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E Desku_2621 DNA repair protein recO K03584 recO; DNA repair protein RecO (recombination protein O)
E Desku_0027 Recombination protein recR K06187 recR; recombination protein RecR
E Desku_1922 DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
E Desku_0763 Recombination protein U K03700 recU; recombination protein U
E Desku_0666 Holliday junction ATP-dependent DNA helicase ruvA K03550 ruvA; holliday junction DNA helicase RuvA
E Desku_0667 Holliday junction ATP-dependent DNA helicase ruvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E Desku_0665 Crossover junction endodeoxyribonuclease ruvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
E Desku_0687 ATP-dependent helicase/nuclease subunit A K16898 addA; ATP-dependent helicase/nuclease subunit A [EC:5.6.2.4 3.1.-.-]
E Desku_0686 ATP-dependent helicase/deoxyribonuclease subunit B K16899 addB; ATP-dependent helicase/nuclease subunit B [EC:5.6.2.4 3.1.-.-]
D Other HR factor
E Desku_2971 CRISPR-associated protein Cas1 K15342 cas1; CRISP-associated protein Cas1
E Desku_0607 CRISPR-associated protein Cas1 K15342 cas1; CRISP-associated protein Cas1
E Desku_0457 CRISPR-associated protein Cas1 K15342 cas1; CRISP-associated protein Cas1
D Archaeal homologous recombinant proteins
E Desku_1408 resolvase, Holliday junction-type K03552 hjr; holliday junction resolvase [EC:3.1.21.10]
E Desku_0917 SMC domain protein K03546 sbcC; DNA repair protein SbcC/Rad50
E Desku_0689 SMC domain protein K03546 sbcC; DNA repair protein SbcC/Rad50
E Desku_0688 nuclease SbcCD, D subunit K03547 sbcD; DNA repair protein SbcD/Mre11
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
E Desku_0982 DNA repair protein K10979 ku; DNA end-binding protein Ku
E Desku_0985 DNA polymerase LigD, polymerase domain protein K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1]
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F Desku_0006 DNA gyrase, A subunit K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F Desku_0005 DNA gyrase, B subunit K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F Desku_0987 DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F Desku_0204 histone family protein DNA-binding protein K03530 hupB; DNA-binding protein HU-beta
F Desku_1605 histone family protein DNA-binding protein K03530 hupB; DNA-binding protein HU-beta
F Desku_1613 hypothetical protein K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F Desku_2113 single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F Desku_2621 DNA repair protein recO K03584 recO; DNA repair protein RecO (recombination protein O)
F Desku_0027 Recombination protein recR K06187 recR; recombination protein RecR
F Desku_1684 DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
E Supressor
F Desku_3307 UvrABC system protein A K03701 uvrA; excinuclease ABC subunit A
F Desku_3309 UvrABC system protein B K03702 uvrB; excinuclease ABC subunit B
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D Desku_0193 DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
C Other SOS response factors
D Desku_2381 Protein recA K03553 recA; recombination protein RecA
D Desku_0970 Peptidase S24/S26A/S26B, conserved region K01356 lexA; repressor LexA [EC:3.4.21.88]
D Desku_1356 SOS-response transcriptional repressor, LexA K01356 lexA; repressor LexA [EC:3.4.21.88]
D Desku_1236 phage repressor like transcriptional regulator, XRE family K01356 lexA; repressor LexA [EC:3.4.21.88]
D Desku_1922 DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D Desku_0903 single-strand binding protein K03111 ssb; single-strand DNA-binding protein
D Desku_3551 single-strand binding protein K03111 ssb; single-strand DNA-binding protein
B Other factors with a suspected DNA repair function
C DNA polymerase
D Desku_0651 PHP domain protein K02347 polX; DNA polymerase (family X)
C DNA helicases
D Desku_1437 DNA polymerase III, epsilon subunit K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
C Modulation of nucleotide pools
D Desku_2334 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
C Others
D Desku_2541 phosphoesterase RecJ domain protein K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024