+F	Repair protein	KO
#<h2><a href="/kegg/brite.html"><img src="/Fig/bget/kegg3.gif" align="middle" border=0></a>&nbsp; DNA Repair and Recombination Proteins - Danio rerio (zebrafish)</h2>
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A<b>Eukaryotic type</b>
B  SSBR (single strand breaks repair)
C    Direct repair
D      553368 mgmt; methylated-DNA--protein-cysteine methyltransferase isoform 1	K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63] 
D      569291 alkbh2; DNA oxidative demethylase ALKBH2	K10859 ALKBH2; DNA oxidative demethylase [EC:1.14.11.33] 
D      792266 alkbh3; alpha-ketoglutarate-dependent dioxygenase alkB homolog 3	K10860 ALKBH3; mRNA N1-methyladenine demethylase [EC:1.14.11.54] 
D      100332599 ascc3; activating signal cointegrator 1 complex subunit 3	K18663 ASCC3; activating signal cointegrator complex subunit 3 [EC:5.6.2.4] 
D      394039 cpdp; CPD photolyase	K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3] 
C    BER (base exicision repair)
D      DNA glycosylases
E        393949 unga; uracil DNA glycosylase a	K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27] 
E        571301 ungb; uracil-DNA glycosylase	K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27] 
E        101883490 ccno; cyclin-O	K10861 UDG2; uracil-DNA glycosylase 2 [EC:3.2.2.-] 
E        553789 tdg.1; thymine DNA glycosylase, tandem duplicate 1	K20813 TDG; thymine-DNA glycosylase [EC:3.2.2.29] 
E        558951 tdg.2; G/T mismatch-specific thymine DNA glycosylase-like isoform X2	K20813 TDG; thymine-DNA glycosylase [EC:3.2.2.29] 
E        566516 mpg; DNA-3-methyladenine glycosylase	K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21] 
E        570901 smug1; single-strand-selective monofunctional uracil-DNA glycosylase 1	K10800 SMUG1; single-strand selective monofunctional uracil DNA glycosylase [EC:3.2.2.-] 
E        558403 mutyh; adenine DNA glycosylase	K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31] 
E        101887128 mbd4; methyl-CpG-binding domain protein 4 isoform X1	K10801 MBD4; methyl-CpG-binding domain protein 4 [EC:3.2.2.-] 
E        791194 ogg1; N-glycosylase/DNA lyase	K03660 OGG1; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18] 
E        393253 neil1; endonuclease 8-like 1	K10567 NEIL1; endonuclease VIII-like 1 [EC:3.2.2.- 4.2.99.18] 
E        492463 neil3; endonuclease 8-like 3	K10569 NEIL3; endonuclease VIII-like 3 [EC:3.2.2.- 4.2.99.18] 
E        100008368 nthl1; endonuclease III-like protein 1	K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] 
D      AP endonucleases
E        406730 apex1; DNA repair nuclease APEX1 isoform 1	K10771 APEX1; AP endonuclease 1 [EC:3.1.11.2] 
E        558198 si:ch211-141o9.10; uncharacterized protein si:ch211-141o9.10 isoform X2	K10771 APEX1; AP endonuclease 1 [EC:3.1.11.2] 
E        393115 apex2; DNA-(apurinic or apyrimidinic site) lyase 2	K10772 APEX2; AP endonuclease 2 [EC:3.1.11.2] 
D      Long Patch-BER factors
E        DNA polymerase delta complex
F          556456 pold1; DNA polymerase delta catalytic subunit	K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7] 
F          796456 pold2; DNA polymerase delta subunit 2	K02328 POLD2; DNA polymerase delta subunit 2 
F          692256 pold3; DNA polymerase delta subunit 3	K03504 POLD3; DNA polymerase delta subunit 3 
F          571834 pold4; DNA polymerase delta subunit 4	K03505 POLD4; DNA polymerase delta subunit 4 
E        DNA polymerase epsilon complex
F          553405 pole; DNA polymerase epsilon catalytic subunit A	K02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7] 
F          192320 pole2; DNA polymerase epsilon subunit 2	K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7] 
F          393774 pole3; DNA polymerase epsilon subunit 3	K02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7] 
F          553610 pole4; DNA polymerase epsilon subunit 4	K03506 POLE4; DNA polymerase epsilon subunit 4 [EC:2.7.7.7] 
E        30678 pcna; proliferating cell nuclear antigen	K04802 PCNA; proliferating cell nuclear antigen 
E        386707 fen1; flap endonuclease 1	K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-] 
E        550274 zgc:110269; probable flap endonuclease 1 homolog	K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-] 
E        556995 lig1; DNA ligase 1	K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7] 
D      Short Patch-BER factors
E        554204 polb; DNA polymerase beta	K02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-] 
E        445480 xrcc1; DNA repair protein XRCC1	K10803 XRCC1; DNA-repair protein XRCC1 
E        550335 xndc1; uncharacterized protein LOC550335	K10803 XRCC1; DNA-repair protein XRCC1 
E        563276 lig3; DNA ligase 3	K10776 LIG3; DNA ligase 3 [EC:6.5.1.1] 
D      Other BER factors
E        571485 tdp1; tyrosyl-DNA phosphodiesterase 1	K10862 TDP1; tyrosyl-DNA phosphodiesterase 1 [EC:3.1.4.-] 
E        405797 aptx; aprataxin	K10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72] 
E        101884102 aplf; aprataxin and PNK-like factor	K13295 APLF; aprataxin and PNK-like factor [EC:3.1.-.-] 
E        569462 pnkp; bifunctional polynucleotide phosphatase/kinase	K08073 PNKP; bifunctional polynucleotide phosphatase/kinase [EC:3.1.3.32 2.7.1.78] 
E        110438871 high mobility group protein B1-like	K10802 HMGB1; high mobility group protein B1 
E        321622 hmgb1a; high mobility group protein B1a	K10802 HMGB1; high mobility group protein B1 
E        795095 hmgb1b; high mobility group protein B1b	K10802 HMGB1; high mobility group protein B1 
E        406697 poll; DNA polymerase lambda	K03512 POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-] 
E        560788 parp1; poly [ADP-ribose] polymerase 1	K24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30] 
E        335495 parp3; protein mono-ADP-ribosyltransferase PARP3	K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30] 
E        100007906 parp2; poly [ADP-ribose] polymerase 2	K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30] 
E        558045 parp4; poly [ADP-ribose] polymerase 4 isoform X1	K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30] 
C    NER (nucleotide excision repair)
D      GGR (global genome repair) factors
E        XPC-HR23B-CETN2 complex
F          541386 xpc; DNA repair protein complementing XP-C cells	K10838 XPC; xeroderma pigmentosum group C-complementing protein 
F          393536 rad23b; UV excision repair protein RAD23 homolog B	K10839 RAD23; UV excision repair protein RAD23 
F          445284 rad23aa; RAD23 homolog A, nucleotide excision repair protein a	K10839 RAD23; UV excision repair protein RAD23 
F          562839 rad23ab; RAD23 homolog A, nucleotide excision repair protein b	K10839 RAD23; UV excision repair protein RAD23 
F          100006257 cetn2; centrin-1	K10840 CETN2; centrin-2 
E        Cul4-DDB2 complex
F          449846 rbx1; E3 ubiquitin-protein ligase RBX1	K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32] 
F          560313 cul4b; cullin-4B	K10609 CUL4; cullin 4 
F          394002 cul4a; cullin-4A	K10609 CUL4; cullin 4 
F          393599 ddb1; DNA damage-binding protein 1	K10610 DDB1; DNA damage-binding protein 1 
F          100004133 ddb2; DNA damage-binding protein 2	K10140 DDB2; DNA damage-binding protein 2 
E        NER4 complex
D      TCR (transcription coupled repair) factors
E        DNA-directed RNA polymerase II complex
F          553347 polr2a; DNA-directed RNA polymerase II subunit RPB1	K03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6] 
F          100149268 polr2b; DNA-directed RNA polymerase II subunit RPB2	K03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6] 
F          334669 polr2c; DNA-directed RNA polymerase II subunit RPB3	K03011 RPB3; DNA-directed RNA polymerase II subunit RPB3 
F          436588 polr2d; DNA-directed RNA polymerase II subunit RPB4	K03012 RPB4; DNA-directed RNA polymerase II subunit RPB4 
F          445170 polr2eb; DNA-directed RNA polymerases I, II, and III subunit RPABC1	K03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1 
F          100330570 polr2ea; DNA-directed RNA polymerases I, II, and III subunit RPABC1-like	K03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1 
F          436817 polr2f; DNA-directed RNA polymerases I, II, and III subunit RPABC2	K03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2 
F          324088 polr2g; DNA-directed RNA polymerase II subunit RPB7	K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7 
F          550263 polr2h; DNA-directed RNA polymerases I, II, and III subunit RPABC3	K03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3 
F          449992 polr2i; DNA-directed RNA polymerase II subunit RPB9	K03017 RPB9; DNA-directed RNA polymerase II subunit RPB9 
F          553705 polr2l; DNA-directed RNA polymerases I, II, and III subunit RPABC5	K03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5 
F          554099 polr2j; DNA-directed RNA polymerase II subunit RPB11-a	K03008 RPB11; DNA-directed RNA polymerase II subunit RPB11 
F          796803 polr2k; DNA-directed RNA polymerases I, II, and III subunit RPABC4	K03009 RPABC4; DNA-directed RNA polymerases I, II, and III subunit RPABC4 
E        Cul4-CSA complex
F          449846 rbx1; E3 ubiquitin-protein ligase RBX1	K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32] 
F          560313 cul4b; cullin-4B	K10609 CUL4; cullin 4 
F          394002 cul4a; cullin-4A	K10609 CUL4; cullin 4 
F          393599 ddb1; DNA damage-binding protein 1	K10610 DDB1; DNA damage-binding protein 1 
F          449811 ercc8; DNA excision repair protein ERCC-8	K10570 ERCC8; DNA excision repair protein ERCC-8 
E        Other TCR factor
F          560477 ercc6; DNA excision repair protein ERCC-6	K10841 ERCC6; DNA excision repair protein ERCC-6 
F          402864 uvssa; UV-stimulated scaffold protein A	K23720 UVSSA; UV-stimulated scaffold protein A 
F          393357 elof1; transcription elongation factor 1 homolog	K25829 ELOF1; transcription elongation factor 1 
D      TFIIH complex
E        324323 ercc3; general transcription and DNA repair factor IIH helicase subunit XPB	K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4] 
E        393900 ercc2; general transcription and DNA repair factor IIH helicase subunit XPD	K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3] 
E        447857 gtf2h1; general transcription factor IIH subunit 1	K03141 TFIIH1; transcription initiation factor TFIIH subunit 1 
E        323239 gtf2h2; general transcription factor IIH subunit 2	K03142 TFIIH2; transcription initiation factor TFIIH subunit 2 
E        436837 gtf2h3; general transcription factor IIH subunit 3	K03143 TFIIH3; transcription initiation factor TFIIH subunit 3 
E        334839 gtf2h4; general transcription factor IIH subunit 4	K03144 TFIIH4; transcription initiation factor TFIIH subunit 4 
E        751713 gtf2h5; general transcription factor IIH subunit 5	K10845 TTDA; TFIIH basal transcription factor complex TTD-A subunit 
E        405897 cdk7; cyclin-dependent kinase 7	K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23] 
E        541325 ccnh; cyclin-H	K06634 CCNH; cyclin H 
E        450080 mnat1; CDK-activating kinase assembly factor MAT1	K10842 MNAT1; CDK-activating kinase assembly factor MAT1 
D      RPA (replication factor A)
E        327491 rpa1; replication protein A 70 kDa DNA-binding subunit	K07466 RFA1; replication factor A1 
E        65226 rpa2; replication protein A 32 kDa subunit	K10739 RFA2; replication factor A2 
E        393196 rpa3; replication protein A 14 kDa subunit	K10740 RPA3; replication factor A3 
D      Other NER factors
E        393443 xpa; DNA repair protein complementing XP-A cells	K10847 XPA; DNA-repair protein complementing XP-A cells 
E        100001425 ercc1; DNA excision repair protein ERCC-1	K10849 ERCC1; DNA excision repair protein ERCC-1 
E        327322 ercc4; DNA repair endonuclease XPF	K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-] 
E        541502 ercc5; DNA repair protein complementing XP-G cells	K10846 ERCC5; DNA excision repair protein ERCC-5 
E        556995 lig1; DNA ligase 1	K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7] 
E        563643 mms19; MMS19 nucleotide excision repair protein homolog	K15075 MET18; DNA repair/transcription protein MET18/MMS19 
E        324655 cul3a; cullin-3a	K03869 CUL3; cullin 3 
E        572370 cul3b; cullin-3b	K03869 CUL3; cullin 3 
E        100006147 cul5b; cullin-5 isoform X4	K10612 CUL5; cullin 5 
E        327215 cul5a; cullin-5a	K10612 CUL5; cullin 5 
E        436713 elocb; elongin C paralog b	K03872 ELOC; elongin-C 
E        447935 eloca; elongin C paralog a	K03872 ELOC; elongin-C 
E        192341 elob; elongin-B	K03873 ELOB; elongin-B 
E        406764 eloa; elongin-A	K15076 ELOA; elongin-A 
E        768168 eloal; elongin A, like	K15076 ELOA; elongin-A 
E        100034477 ubap2l; ubiquitin-associated protein 2-like	K26545 UBAP2; ubiquitin-associated protein 2 
E        563733 ubap2a; ubiquitin-associated protein 2a	K26545 UBAP2; ubiquitin-associated protein 2 
C    MMR (mismatch excision repair)
D      Mismatch and loop recognition factors
E        406845 msh2; DNA mismatch repair protein Msh2	K08735 MSH2; DNA mismatch repair protein MSH2 
E        565400 msh3; DNA mismatch repair protein Msh3	K08736 MSH3; DNA mismatch repair protein MSH3 
E        260437 msh6; DNA mismatch repair protein Msh6	K08737 MSH6; DNA mismatch repair protein MSH6 
D      MutL homologs
E        368631 pms1; PMS1 protein homolog 1	K10864 PMS1; DNA mismatch repair protein PMS1 
E        393632 mlh1; DNA mismatch repair protein Mlh1	K08734 MLH1; DNA mismatch repair protein MLH1 
E        565276 pms2; mismatch repair endonuclease PMS2	K10858 PMS2; DNA mismatch repair protein PMS2 
E        568323 mlh3; DNA mismatch repair protein Mlh3 isoform X1	K08739 MLH3; DNA mismatch repair protein MLH3 
D      DNA polymerase delta complex
E        556456 pold1; DNA polymerase delta catalytic subunit	K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7] 
E        796456 pold2; DNA polymerase delta subunit 2	K02328 POLD2; DNA polymerase delta subunit 2 
E        692256 pold3; DNA polymerase delta subunit 3	K03504 POLD3; DNA polymerase delta subunit 3 
E        571834 pold4; DNA polymerase delta subunit 4	K03505 POLD4; DNA polymerase delta subunit 4 
D      RPA (replication factor A)
E        327491 rpa1; replication protein A 70 kDa DNA-binding subunit	K07466 RFA1; replication factor A1 
E        65226 rpa2; replication protein A 32 kDa subunit	K10739 RFA2; replication factor A2 
E        393196 rpa3; replication protein A 14 kDa subunit	K10740 RPA3; replication factor A3 
D      RFC (replication factor C)
E        100037336 rfc1; replication factor C subunit 1	K10754 RFC1; replication factor C subunit 1 
E        406435 rfc4; replication factor C subunit 4	K10755 RFC2_4; replication factor C subunit 2/4 
E        503748 rfc2; replication factor C subunit 2	K10755 RFC2_4; replication factor C subunit 2/4 
E        445385 rfc5; replication factor C subunit 5	K10756 RFC3_5; replication factor C subunit 3/5 
E        259256 rfc3; replication factor C subunit 3	K10756 RFC3_5; replication factor C subunit 3/5 
D      Other MMR factors
E        30678 pcna; proliferating cell nuclear antigen	K04802 PCNA; proliferating cell nuclear antigen 
E        406778 exo1; exonuclease 1	K10746 EXO1; exonuclease 1 [EC:3.1.-.-] 
E        110438871 high mobility group protein B1-like	K10802 HMGB1; high mobility group protein B1 
E        321622 hmgb1a; high mobility group protein B1a	K10802 HMGB1; high mobility group protein B1 
E        795095 hmgb1b; high mobility group protein B1b	K10802 HMGB1; high mobility group protein B1 
E        556995 lig1; DNA ligase 1	K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7] 
E        570063 wdr76; WD repeat-containing protein 76	K24755 WDR76; WD repeat-containing protein 76 
B  DSBR (double strand breaks repair)
C    HR (homologous recombination)
D      MRN(MRX) complex
E        406637 mre11a; double-strand break repair protein MRE11	K10865 MRE11; double-strand break repair protein MRE11 
E        553029 rad50; DNA repair protein RAD50	K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-] 
E        544655 nbn; nibrin	K10867 NBN; nibrin 
D      BRCA1-core complex
E        100147913 bard1; BRCA1-associated RING domain protein 1	K10683 BARD1; BRCA1-associated RING domain protein 1 
D      BRCA1-A complex
E        449820 abraxas1; BRCA1-A complex subunit Abraxas 1	K20774 FAM175A; BRCA1-A complex subunit Abraxas 
E        100535018 uimc1; BRCA1-A complex subunit RAP80	K20775 UIMC1; BRCA1-A complex subunit RAP80 
E        445296 babam1; BRISC and BRCA1-A complex member 1	K20776 BABAM; BRISC and BRCA1-A complex member 1 
E        550474 babam2; BRISC and BRCA1-A complex member 2	K12173 BRE; BRCA1-A complex subunit BRE 
E        100333845 brcc3; lys-63-specific deubiquitinase	K11864 BRCC3; BRCA1/BRCA2-containing complex subunit 3 [EC:3.4.19.-] 
D      BRCA1-B complex
E        794038 brip1; Fanconi anemia group J protein	K15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3] 
E        407679 topbp1; DNA topoisomerase 2-binding protein 1	K10728 TOPBP1; topoisomerase (DNA) II binding protein 1 
D      BRCA1-C complex
E        503536 rbbp8; DNA endonuclease RBBP8	K20773 RBBP8; DNA endonuclease RBBP8 [EC:3.1.-.-] 
E        406637 mre11a; double-strand break repair protein MRE11	K10865 MRE11; double-strand break repair protein MRE11 
E        553029 rad50; DNA repair protein RAD50	K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-] 
E        544655 nbn; nibrin	K10867 NBN; nibrin 
D      BRCA complex
E        566758 brca2; breast cancer type 2 susceptibility protein	K08775 BRCA2; breast cancer 2 susceptibility protein 
E        558923 palb2; partner and localizer of BRCA2	K10897 PALB2; partner and localizer of BRCA2 
E        406487 rad51; DNA repair protein RAD51 homolog 1	K04482 RAD51; DNA repair protein RAD51 
D      RecA family proteins
E        406487 rad51; DNA repair protein RAD51 homolog 1	K04482 RAD51; DNA repair protein RAD51 
E        406721 rad51b; DNA repair protein RAD51 homolog 2	K10869 RAD51L1; RAD51-like protein 1 
E        450081 rad51c; DNA repair protein RAD51 homolog 3	K10870 RAD51L2; RAD51-like protein 2 
E        404608 rad51d; DNA repair protein RAD51 homolog 4	K10871 RAD51L3; RAD51-like protein 3 
E        553395 xrcc2; DNA repair protein XRCC2 isoform 1	K10879 XRCC2; DNA-repair protein XRCC2 
E        541414 xrcc3; DNA repair protein XRCC3	K10880 XRCC3; DNA-repair protein XRCC3 
D      Rad52 family proteins
E        554171 rad52; DNA repair protein RAD52 homolog	K10873 RAD52; DNA repair and recombination protein RAD52 
E        492461 rdm1; RAD52 motif-containing protein 1	K10874 RDM1; RAD52 motif-containing protein 1 
D      Rad54 family proteins
E        394119 rad54l; DNA repair and recombination protein RAD54-like	K10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-] 
E        558947 rad54l2; helicase ARIP4 isoform X1	K10876 RAD54L2; RAD54-like protein 2 [EC:5.6.2.-] 
E        560482 rad54b; DNA repair and recombination protein RAD54B	K10877 RAD54B; DNA repair and recombination protein RAD54B [EC:5.6.2.-] 
D      RecQ family DNA helicases
E        566018 recql; ATP-dependent DNA helicase Q1	K10899 RECQL; ATP-dependent DNA helicase Q1 [EC:5.6.2.4] 
E        569495 wrn; Werner syndrome ATP-dependent helicase	K10900 WRN; werner syndrome ATP-dependent helicase [EC:5.6.2.4] 
E        572540 blm; Bloom syndrome protein isoform X1	K10901 BLM; bloom syndrome protein [EC:5.6.2.4] 
E        567383 recql4; ATP-dependent DNA helicase Q4	K10730 RECQL4; ATP-dependent DNA helicase Q4 [EC:5.6.2.4] 
E        566553 recql5; ATP-dependent DNA helicase Q5	K10902 RECQL5; ATP-dependent DNA helicase Q5 [EC:5.6.2.4] 
D      Bloom's syndrome complex (BTR)
E        572540 blm; Bloom syndrome protein isoform X1	K10901 BLM; bloom syndrome protein [EC:5.6.2.4] 
E        560212 top3a; DNA topoisomerase 3-alpha	K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1] 
E        793414 top3b; DNA topoisomerase 3-beta-1 isoform X1	K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1] 
E        393149 rmi1; recQ-mediated genome instability protein 1	K10990 RMI1; RecQ-mediated genome instability protein 1 
E        563218 rmi2; recQ-mediated genome instability protein 2	K15365 RMI2; RecQ-mediated genome instability protein 2 
D      RPA (replication factor A)
E        327491 rpa1; replication protein A 70 kDa DNA-binding subunit	K07466 RFA1; replication factor A1 
E        65226 rpa2; replication protein A 32 kDa subunit	K10739 RFA2; replication factor A2 
E        393196 rpa3; replication protein A 14 kDa subunit	K10740 RPA3; replication factor A3 
D      Protein phosphatase 4
E        100003080 ppp4ca; serine/threonine-protein phosphatase 4 catalytic subunit A	K15423 PPP4C; serine/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16] 
E        562705 ppp4cb; serine/threonine-protein phosphatase 4 catalytic subunit B	K15423 PPP4C; serine/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16] 
E        393230 ppp4r1; serine/threonine-protein phosphatase 4 regulatory subunit 1	K15424 PPP4R1; serine/threonine-protein phosphatase 4 regulatory subunit 1 
E        569680 ppp4r1l; serine/threonine-protein phosphatase 4 regulatory subunit 1-like isoform X2	K15424 PPP4R1; serine/threonine-protein phosphatase 4 regulatory subunit 1 
E        100005419 ppp4r2b; serine/threonine-protein phosphatase 4 regulatory subunit 2-B	K15425 PPP4R2; serine/threonine-protein phosphatase 4 regulatory subunit 2 
E        326723 ppp4r2a; serine/threonine-protein phosphatase 4 regulatory subunit 2-A	K15425 PPP4R2; serine/threonine-protein phosphatase 4 regulatory subunit 2 
E        336198 ppp4r3b; serine/threonine-protein phosphatase 4 regulatory subunit 3B	K17491 SMEK; protein phosphatase 4 regulatory subunit 3 
E        558578 smek1; serine/threonine-protein phosphatase 4 regulatory subunit 3	K17491 SMEK; protein phosphatase 4 regulatory subunit 3 
E        567930 ppp4r4; serine/threonine-protein phosphatase 4 regulatory subunit 4 isoform X1	K15426 PPP4R4; serine/threonine-protein phosphatase 4 regulatory subunit 4 
D      AP-5 complex
E        100148772 ap5b1; AP-5 complex subunit beta-1	K19022 AP5B1; AP-5 complex subunit beta-1 
E        553681 ap5m1; AP-5 complex subunit mu-1	K19023 AP5M1; AP-5 complex subunit mu-1 
E        556111 ap5s1; AP-5 complex subunit sigma-1 precursor	K19024 AP5S1; AP-5 complex subunit sigma-1 
E        100537934 ap5z1; AP-5 complex subunit zeta-1	K19025 AP5Z1; AP-5 complex subunit zeta-1 
D      SMC5-SMC6 complex
E        566749 smc5; structural maintenance of chromosomes protein 5	K22803 SMC5; structural maintenance of chromosomes protein 5 
E        557127 si:dkey-119f1.1; Structural maintenance of chromosomes protein 6-like	K22804 SMC6; structural maintenance of chromosomes protein 6 
E        797304 smc6; structural maintenance of chromosomes protein 6 isoform X2	K22804 SMC6; structural maintenance of chromosomes protein 6 
E        393590 lratd1; protein LRATD1	K22805 FAM84A; protein FAM84A 
E        436824 nsmce1; non-structural maintenance of chromosomes element 1 homolog	K22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27] 
E        564644 nsmce2; E3 SUMO-protein ligase NSE2	K22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-] 
E        386658 ndnl2; necdin-like 2	K22823 NSMCE3; non-structural maintenance of chromosomes element 3 
E        553544 nsmce4a; non-structural maintenance of chromosomes element 4 homolog A	K22825 NSMCE4; non-structural maintenance of chromosomes element 4 
E        101882450 slf1; SMC5-SMC6 complex localization factor protein 1	K26126 SLF1; SMC5-SMC6 complex localization factor protein 1 
E        100320914 slf2; SMC5-SMC6 complex localization factor protein 2 isoform X3	K26127 SLF2; SMC5-SMC6 complex localization factor protein 2 
D      Other HR factors
E        558350 eme1; crossover junction endonuclease EME1	K10882 EME1; crossover junction endonuclease EME1 [EC:3.1.22.-] 
E        100332307 eme2; probable crossover junction endonuclease EME2	K10882 EME1; crossover junction endonuclease EME1 [EC:3.1.22.-] 
E        334455 exd2; exonuclease 3'-5' domain-containing protein 2	K20777 EXD2; exonuclease 3'-5' domain-containing protein 2 [EC:3.1.11.1] 
E        406839 mus81; crossover junction endonuclease MUS81	K08991 MUS81; crossover junction endonuclease MUS81 [EC:3.1.22.-] 
E        322269 sem1; 26S proteasome complex subunit SEM1	K10881 SHFM1; 26 proteasome complex subunit DSS1 
E        100333759 swi5; DNA repair protein SWI5 homolog	K10991 SWI5; DNA repair protein Swi5/Sae3 
E        568747 sfr1; swi5-dependent recombination DNA repair protein 1 homolog	K10992 SFR1; Swi5-dependent recombination DNA repair protein 1 
E        100001845 slx1b; structure-specific endonuclease subunit SLX1	K15078 SLX1; structure-specific endonuclease subunit SLX1 [EC:3.6.1.-] 
E        100538153 slx4; structure-specific endonuclease subunit SLX4	K10484 BTBD12; structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12) 
E        101884233 gen1; flap endonuclease GEN homolog 1 isoform X2	K15338 GEN1; holliday junction resolvase GEN1/YEN1 [EC:3.1.-.-] 
E        793551 spg11; spatacsin isoform 2	K19026 SPG11; spatacsin 
E        324565 zfyve26; zinc finger FYVE domain-containing protein 26	K19027 ZFYVE26; zinc finger FYVE domain-containing protein 26 
E        555714 rad51ap1; RAD51-associated protein 1	K20778 RAD51AP1; RAD51-associated protein 1 
E        436877 morf4l1; mortality factor 4-like protein 1	K11339 MORF4L1; mortality factor 4-like protein 1 
E        553453 samhd1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1	K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-] 
E        793232 deoxynucleoside triphosphate triphosphohydrolase SAMHD1-like	K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-] 
E        100333959 si:ch211-233g6.2; deoxynucleoside triphosphate triphosphohydrolase SAMHD1-like	K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-] 
E        569539 fignl1; fidgetin-like protein 1	K22766 FIGNL1; fidgetin-like protein 1 [EC:5.6.2.-] 
E        100535045 spidr; DNA repair-scaffolding protein	K22806 SPIDR; DNA repair-scaffolding protein 
E        550535 lratd2b; uncharacterized protein LOC550535	K22810 FAM84B; protein FAM84B 
E        767732 lratd2a; protein LRATD2a	K22810 FAM84B; protein FAM84B 
E        678547 brat1; BRCA1-associated ATM activator 1	K23112 BRAT1; BRCA1-associated ATM activator 1 
E        100537391 cfap410; cilia and flagella associated protein 410	K23456 CFAP410; cilla- and flagella-associated protein 
E        80965 hdgfl2; hepatoma-derived growth factor-related protein 2	K25065 HDGFL2; hepatoma-derived growth factor-related protein 2 
E        325530 zswim7; zinc finger SWIM domain-containing protein 7	K25770 ZSWIM7; zinc finger SWIM domain-containing protein 7 
E        100329809 swsap1; ATPase SWSAP1	K25771 SWSAP1; ATPase SWSAP1 
E        335889 emsy; BRCA2-interacting transcriptional repressor EMSY	K25790 EMSY; BRCA2-interacting transcriptional repressor EMSY 
E        565831 hsf2bp; heat shock factor 2-binding protein	K25791 HSF2BP; heat shock factor 2-binding protein 
E        563411 mms22l; protein MMS22-like	K26125 MMS22L; protein MMS22-like 
E        492655 tonsl; tonsoku-like protein	K09257 NFKBIL2; NF-kappa-B inhibitor-like protein 2 
E        100332682 bod1l1; biorientation of chromosomes in cell division protein 1-like 1 isoform X1	K27262 BOD1L1; biorientation of chromosomes in cell division protein 1-like 1 
E        678635 parpbp; PCNA-interacting partner	K27412 PARPBP; PCNA-interacting partner 
C    NHEJ (non-homologous end-joining)
D      DNA-PK complex
E        334488 xrcc6; X-ray repair cross-complementing protein 6	K10884 XRCC6; ATP-dependent DNA helicase 2 subunit 1 
E        449848 xrcc5; X-ray repair cross-complementing protein 5	K10885 XRCC5; ATP-dependent DNA helicase 2 subunit 2 
E        562283 prkdc; DNA-dependent protein kinase catalytic subunit	K06642 PRKDC; DNA-dependent protein kinase catalytic subunit [EC:2.7.11.1] 
D      MRX complex
E        406637 mre11a; double-strand break repair protein MRE11	K10865 MRE11; double-strand break repair protein MRE11 
E        553029 rad50; DNA repair protein RAD50	K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-] 
D      DNA Ligase 4 complex
E        569525 lig4; DNA ligase 4	K10777 LIG4; DNA ligase 4 [EC:6.5.1.1] 
E        393759 xrcc4; DNA repair protein XRCC4	K10886 XRCC4; DNA-repair protein XRCC4 
E        406593 nhej1; non-homologous end-joining factor 1	K10980 NHEJ1; non-homologous end-joining factor 1 
D      X-family DNA polymerases
E        406697 poll; DNA polymerase lambda	K03512 POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-] 
E        393218 polm; DNA-directed DNA/RNA polymerase mu	K03513 POLM; DNA polymerase mu [EC:2.7.7.7] 
E        544653 dntt; DNA nucleotidylexotransferase	K00977 DNTT; DNA nucleotidylexotransferase [EC:2.7.7.31] 
E        554204 polb; DNA polymerase beta	K02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-] 
D      Other NHEJ factors
E        405797 aptx; aprataxin	K10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72] 
E        101884102 aplf; aprataxin and PNK-like factor	K13295 APLF; aprataxin and PNK-like factor [EC:3.1.-.-] 
E        566285 dclre1c; protein artemis	K10887 DCLRE1C; DNA cross-link repair 1C protein [EC:3.1.-.-] 
E        553516 tdp2b; tyrosyl-DNA phosphodiesterase 2	K19619 TDP2; tyrosyl-DNA phosphodiesterase 2 [EC:3.1.4.-] 
E        101887157 tyrosyl-DNA phosphodiesterase 2-like	K19619 TDP2; tyrosyl-DNA phosphodiesterase 2 [EC:3.1.4.-] 
E        497282 smchd1; structural maintenance of chromosomes flexible hinge domain-containing protein 1	K23113 SMCHD1; structural maintenance of chromosomes flexible hinge domain-containing protein 1 
E        100007612 si:dkey-127k13.1; serine/arginine repetitive matrix protein 1 isoform X1	K23386 PWWP3; PWWP domain-containing DNA repair factor 3 
E        492631 paxx; protein PAXX	K25772 PAXX; protein PAXX 
E        100001877 si:ch211-127m7.2; uncharacterized protein si:ch211-127m7.2	K26155 CYREN; cell cycle regulator of non-homologous end joining 
E        100330060 jmjd8; jmjC domain-containing protein 8	K25792 JMJD8; jumonji domain-containing protein 8 
E        100149820 shld2; shieldin complex subunit 2	K26129 SHLD2; shieldin complex subunit 2 
E        450064 zgc:101664; uncharacterized protein LOC450064	K26130 SHLD3; shieldin complex subunit 3 
C    FA (Fanconi anemia) pathway
D      FA core complex
E        692125 fanca; Fanconi anemia group A protein	K10888 FANCA; fanconi anemia group A protein 
E        692127 fancc; Fanconi anemia group C protein	K10890 FANCC; fanconi anemia group C protein 
E        565685 fance; Fanconi anemia group E protein	K10892 FANCE; fanconi anemia group E protein 
E        692250 fancf; Fanconi anemia group F protein	K10893 FANCF; fanconi anemia group F protein 
E        402936 fancg; Fanconi anemia group G protein	K10894 FANCG; fanconi anemia group G protein 
E        406255 fancl; E3 ubiquitin-protein ligase FANCL	K10606 FANCL; E3 ubiquitin-protein ligase FANCL [EC:2.3.2.27] 
E        100006685 fancm; Fanconi anemia group M protein	K10896 FANCM; fanconi anemia group M protein 
E        559470 faap24; Fanconi anemia core complex-associated protein 24	K10898 FAAP24; fanconi anemia-associated protein 
E        100001169 si:dkey-57h18.1; Fanconi anemia core complex-associated protein 100 isoform X1	K10993 FAAP100; fanconi anemia core complex 100 kDa subunit 
D      FA core complex binding factors
E        30288 her6; hairy-related 6	K06054 HES1; hairy and enhancer of split 1 
E        140613 her9; hairy-related 9	K06054 HES1; hairy and enhancer of split 1 
E        569270 cenps; centromere protein S	K11511 APITD1; centromere protein S 
E        100332714 cenpx; centromere protein X	K15360 STRA13; centromere protein X 
E        768152 ube2t; ubiquitin-conjugating enzyme E2 T	K13960 UBE2T; ubiquitin-conjugating enzyme E2 T [EC:2.3.2.23] 
D      Bloom's syndrome complex (BTR)
E        572540 blm; Bloom syndrome protein isoform X1	K10901 BLM; bloom syndrome protein [EC:5.6.2.4] 
E        560212 top3a; DNA topoisomerase 3-alpha	K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1] 
E        793414 top3b; DNA topoisomerase 3-beta-1 isoform X1	K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1] 
E        393149 rmi1; recQ-mediated genome instability protein 1	K10990 RMI1; RecQ-mediated genome instability protein 1 
E        563218 rmi2; recQ-mediated genome instability protein 2	K15365 RMI2; RecQ-mediated genome instability protein 2 
D      FANCD2-I complex
E        394241 fancd2; Fanconi anemia group D2 protein	K10891 FANCD2; fanconi anemia group D2 protein 
E        324185 fanci; Fanconi anemia group I protein	K10895 FANCI; fanconi anemia group I protein 
D      Downstream FA components
E        566758 brca2; breast cancer type 2 susceptibility protein	K08775 BRCA2; breast cancer 2 susceptibility protein 
E        794038 brip1; Fanconi anemia group J protein	K15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3] 
E        558923 palb2; partner and localizer of BRCA2	K10897 PALB2; partner and localizer of BRCA2 
D      Other FA pathway factors
E        565458 fan1; fanconi-associated nuclease 1	K15363 FAN1; fanconi-associated nuclease 1 [EC:3.1.21.- 3.1.4.1] 
E        406487 rad51; DNA repair protein RAD51 homolog 1	K04482 RAD51; DNA repair protein RAD51 
E        450081 rad51c; DNA repair protein RAD51 homolog 3	K10870 RAD51L2; RAD51-like protein 2 
E        777634 telo2; telomere length regulation protein TEL2 homolog isoform 1	K11137 TELO2; telomere length regulation protein 
E        322007 usp1; ubiquitin carboxyl-terminal hydrolase 1	K11832 USP1; ubiquitin carboxyl-terminal hydrolase 1 [EC:3.4.19.12] 
E        334682 wdr48b; WD repeat-containing protein 48	K15361 WDR48; WD repeat-containing protein 48 
E        777754 wdr48a; WD repeat-containing protein 48a	K15361 WDR48; WD repeat-containing protein 48 
C    Other DSBR factors
D      Protein phosphatase 6
E        393980 ppp6c; serine/threonine-protein phosphatase 6 catalytic subunit	K15498 PPP6C; serine/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16] 
E        560729 ppp6r2a; serine/threonine-protein phosphatase 6 regulatory subunit 2a	K15500 PPP6R2; serine/threonine-protein phosphatase 6 regulatory subunit 2 
E        570360 ppp6r2b; serine/threonine-protein phosphatase 6 regulatory subunit 2	K15500 PPP6R2; serine/threonine-protein phosphatase 6 regulatory subunit 2 
E        324530 ppp6r3; serine/threonine-protein phosphatase 6 regulatory subunit 3	K15501 PPP6R3; serine/threonine-protein phosphatase 6 regulatory subunit 3 
E        560747 ankrd28b; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A	K15502 ANKRD28; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A 
E        100535451 serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A	K15502 ANKRD28; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A 
E        561373 ankrd44; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B isoform X1	K15503 ANKRD44; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B 
E        553206 ankrd52a; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C	K15504 ANKRD52; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C 
E        564614 ankrd52b; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C-like	K15504 ANKRD52; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C 
D      Ubiquitin ligases
E        404050 rnf8; E3 ubiquitin-protein ligase rnf8 isoform 2	K10667 RNF8; E3 ubiquitin-protein ligase RNF8 [EC:2.3.2.27] 
E        334081 rnf168; E3 ubiquitin-protein ligase rnf168	K20779 RNF168; E3 ubiquitin-protein ligase RNF168 [EC:2.3.2.31] 
E        795748 rnf169; E3 ubiquitin-protein ligase RNF169	K20805 RNF169; E3 ubiquitin-protein ligase RNF169 [EC:2.3.2.31] 
E        558479 herc2; E3 ubiquitin-protein ligase HERC2 isoform X3	K10595 HERC2; E3 ubiquitin-protein ligase HERC2 [EC:2.3.2.26] 
D      Others
E        321796 wrap53; telomerase Cajal body protein 1	K23314 WRAP53; telomerase Cajal body protein 1 
E        101882537 tprn; taperin	K24164 TPRN; taperin 
E        101884837 wdr70; WD repeat-containing protein 70	K24752 WDR70; WD repeat-containing protein 70 
E        570063 wdr76; WD repeat-containing protein 76	K24755 WDR76; WD repeat-containing protein 76 
B  TLS (translesion DNA synthesis) factors
C    Y-family DNA polymerases
D      678520 polh; DNA polymerase eta	K03509 POLH; DNA polymerase eta [EC:2.7.7.7] 
D      550532 poli; DNA polymerase iota	K03510 POLI; DNA polymerase iota [EC:2.7.7.7] 
D      562749 polk; DNA polymerase kappa	K03511 POLK; DNA polymerase kappa [EC:2.7.7.7] 
D      570043 rev1; DNA repair protein REV1	K03515 REV1; DNA repair protein REV1 [EC:2.7.7.-] 
C    B-family DNA polymerases
D      569100 rev3l; DNA polymerase zeta catalytic subunit isoform X1	K02350 REV3L; DNA polymerase zeta [EC:2.7.7.7] 
C    A-family DNA polymerase
D      566857 poln; DNA polymerase nu	K16618 POLN; DNA polymerase nu [EC:2.7.7.7] 
C    Rad6 epistasis group
D      325470 ube2al; ubiquitin conjugating enzyme E2 A, like	K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23] 
D      797853 ube2a; ubiquitin-conjugating enzyme E2 A	K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23] 
D      437020 ube2b; ubiquitin-conjugating enzyme E2 B	K10574 UBE2B; ubiquitin-conjugating enzyme E2 B [EC:2.3.2.23] 
D      393106 rad18; E3 ubiquitin-protein ligase RAD18	K10627 RAD18; E3 ubiquitin-protein ligase RAD18 [EC:2.3.2.27] 
D      564651 hltf; helicase-like transcription factor isoform X1	K15711 SMARCA3; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A3 [EC:5.6.2. 2.3.2.27] 
D      641324 ube2v1; ubiquitin-conjugating enzyme E2 variant 1	K10704 UBE2V; ubiquitin-conjugating enzyme E2 variant 
D      406836 ube2v2; ubiquitin-conjugating enzyme E2 variant 2	K10704 UBE2V; ubiquitin-conjugating enzyme E2 variant 
D      393313 ube2nb; ubiquitin-conjugating enzyme E2Nb	K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23] 
D      406807 ube2na; ubiquitin-conjugating enzyme E2Na	K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23] 
C    Other TLS factors
D      30678 pcna; proliferating cell nuclear antigen	K04802 PCNA; proliferating cell nuclear antigen 
D      678635 parpbp; PCNA-interacting partner	K27412 PARPBP; PCNA-interacting partner 
D      101886162 sprtn; DNA-dependent metalloprotease SPRTN	K24051 SPRTN; SprT-like domain-contaning protein Spartan 
D      541448 gcna; germ cell nuclear acidic protein	K26957 GCNA; germ cell nuclear acidic protein 
B  Check point factors
C    Rad9-Hus1-Rad1 complex
D      393176 rad9a; cell cycle checkpoint control protein RAD9A	K10994 RAD9A; cell cycle checkpoint control protein RAD9A [EC:3.1.11.2] 
D      563903 rad9b; cell cycle checkpoint control protein RAD9B	K10995 RAD9B; cell cycle checkpoint control protein RAD9B 
D      100037341 zgc:162895; checkpoint protein HUS1	K10903 HUS1; HUS1 checkpoint protein 
D      393872 rad1; cell cycle checkpoint protein RAD1	K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2] 
C    HRAD17(Rad24)-RFC complex
D      436934 rad17; cell cycle checkpoint protein RAD17	K06662 HRAD17; cell cycle checkpoint protein 
D      406435 rfc4; replication factor C subunit 4	K10755 RFC2_4; replication factor C subunit 2/4 
D      503748 rfc2; replication factor C subunit 2	K10755 RFC2_4; replication factor C subunit 2/4 
D      445385 rfc5; replication factor C subunit 5	K10756 RFC3_5; replication factor C subunit 3/5 
D      259256 rfc3; replication factor C subunit 3	K10756 RFC3_5; replication factor C subunit 3/5 
C    Rad17-Mec3-Ddc1 complex
D      393872 rad1; cell cycle checkpoint protein RAD1	K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2] 
C    FPC (fork protection complex)
D      325855 timeless; protein timeless homolog	K10997 TIMELESS; replication fork protection complex subunit TIMELESS/Tof1/Swi1 
D      445058 tipin; TIMELESS-interacting protein	K10998 TIPIN; replication fork protection complex subunit TIPIN/Csm3/Swi3 
D      564151 clspn; claspin	K25773 CLSPN; claspin 
C    Triple T complex
D      777634 telo2; telomere length regulation protein TEL2 homolog isoform 1	K11137 TELO2; telomere length regulation protein 
D      570077 tti1; TELO2-interacting protein 1 homolog	K20403 TTI1; TELO2-interacting protein 1 
D      100334230 tti2; TELO2-interacting protein 2	K23115 TTI2; TELO2-interacting protein 2 
C    BAG6-UBL4A-GET4 complex
D      751663 bag6l; large proline-rich protein BAG6	K23390 BAG6; large proline-rich protein BAG6 
D      83910 bag6; large proline-rich protein BAG6	K23390 BAG6; large proline-rich protein BAG6 
D      393270 zgc:56596; ubiquitin-like protein 4A	K23388 UBL4; ubiquitin-like protein 4 
D      796309 get4; Golgi to ER traffic protein 4 homolog	K23387 GET4; golgi to ER traffic protein 4 
C    Other check point factors
D      567770 atr; serine/threonine-protein kinase ATR isoform X2	K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1] 
D      558534 atrip; ATR-interacting protein	K10905 ATRIP; ATR interacting protein 
D      403064 atm; serine-protein kinase ATM	K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1] 
D      30590 tp53; cellular tumor antigen p53 isoform 2	K04451 TP53; tumor protein p53 
D      393162 chek1; serine/threonine-protein kinase Chk1	K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1] 
D      336998 chek2; serine/threonine-protein kinase Chk2	K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1] 
D      57925 cdc25b; M-phase inducer phosphatase 2	K05866 CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48] 
D      406419 ywhabb; 14-3-3 protein beta/alpha-B	K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta 
D      335195 ywhaqb; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b	K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta 
D      323055 ywhaba; 14-3-3 protein beta/alpha-A	K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta 
D      399487 ywhaqa; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide a	K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta 
D      321729 ywhabl; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide like	K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta 
D      336610 ywhaz; 14-3-3 protein zeta/delta	K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta 
D      117604 ywhag1; 14-3-3 protein gamma-1	K16198 YWHAG_H; 14-3-3 protein gamma/eta 
D      560560 ywhag2; 14-3-3 protein gamma-1	K16198 YWHAG_H; 14-3-3 protein gamma/eta 
D      406443 ywhah; 14-3-3 protein eta	K16198 YWHAG_H; 14-3-3 protein gamma/eta 
D      322060 ywhae1; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 1	K06630 YWHAE; 14-3-3 protein epsilon 
D      503763 ywhae2; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 2	K06630 YWHAE; 14-3-3 protein epsilon 
D      100333160 nav2a; neuron navigator 2 isoform X1	K19483 NAV2; neuron navigator 2 [EC:5.6.2.4] 
D      557290 nav2b; neuron navigator 2 isoform X4	K19483 NAV2; neuron navigator 2 [EC:5.6.2.4] 
D      327060 wee1; wee1-like protein kinase	K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1] 
D      327471 wee2; wee1-like protein kinase 2 isoform 2	K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1] 
D      563926 per1a; period circadian protein homolog 1a	K21944 PER1; period circadian protein 1 
D      406204 per1b; period circadian protein homolog 1b	K21944 PER1; period circadian protein 1 
D      140633 per2; period circadian protein homolog 2	K02633 PER2; period circadian protein 2 
D      58107 per3; period circadian protein homolog 3	K21945 PER3; period circadian protein 3 
D      569805 mdc1; mediator of DNA damage checkpoint protein 1	K20780 MDC1; mediator of DNA damage checkpoint protein 1 
D      436598 pls3; plastin-3	K17336 PLS3; plastin-3 
D      100534720 isg20; apoptosis-enhancing nuclease	K18340 AEN; apoptosis-enhancing nuclease [EC:3.1.-.-] 
D      334202 plk3; serine/threonine-protein kinase PLK3	K08862 PLK3; polo-like kinase 3 [EC:2.7.11.21] 
D      556002 nek1; serine/threonine-protein kinase Nek1 isoform X1	K08857 NEK1_4_5; serine/threonine-protein kinase Nek1/4/5 [EC:2.7.11.1] 
D      393987 nek4; serine/threonine-protein kinase Nek4	K08857 NEK1_4_5; serine/threonine-protein kinase Nek1/4/5 [EC:2.7.11.1] 
D      100333839 nek10; serine/threonine-protein kinase Nek10 isoform X1	K20879 NEK10; serine/threonine-protein kinase Nek10 [EC:2.7.11.1] 
D      101883026 nek11; serine/threonine-protein kinase Nek11	K20880 NEK11; serine/threonine-protein kinase Nek11 [EC:2.7.11.1] 
D      110439729 donson; protein downstream neighbor of Son	K22422 DONSON; protein downstream neighbor of Son 
D      101884737 kank4; KN motif and ankyrin repeat domain-containing protein 4 isoform X1	K22808 KANK; KN motif and ankyrin repeat domain-containing protein 
D      558407 kank3; KN motif and ankyrin repeat domain-containing protein 3	K22808 KANK; KN motif and ankyrin repeat domain-containing protein 
D      561164 kank1b; KN motif and ankyrin repeat domain-containing protein 1b	K22808 KANK; KN motif and ankyrin repeat domain-containing protein 
D      571549 kank2; KN motif and ankyrin repeat domain-containing protein 2	K22808 KANK; KN motif and ankyrin repeat domain-containing protein 
D      777729 kank1a; KN motif and ankyrin repeat domain-containing protein 1a	K22808 KANK; KN motif and ankyrin repeat domain-containing protein 
D      406766 chmp4bb; charged multivesicular body protein 4c	K24782 CHMP4C; charged multivesicular body protein 4C 
D      550542 chmp4c; charged multivesicular body protein 4c	K24782 CHMP4C; charged multivesicular body protein 4C 
D      393880 vps4b; vacuolar protein sorting-associated protein 4B	K12196 VPS4; vacuolar protein-sorting-associated protein 4 
D      767670 vps4a; vacuolar protein sorting-associated protein 4A	K12196 VPS4; vacuolar protein-sorting-associated protein 4 
D      436685 zfyve19; abscission/NoCut checkpoint regulator	K24778 ZFYVE19; abscission/NoCut checkpoint regulator 
D      550448 sde2; splicing regulator SDE2	K25059 SDE2; replication stress response regulator SDE2 
B  Other factors with a suspected DNA repair function
C    DNA polymerases
D      566079 polq; DNA polymerase theta	K02349 POLQ; DNA polymerase theta [EC:2.7.7.7] 
D      321277 mybbp1a; myb-binding protein 1A-like protein	K02331 POL5; DNA polymerase phi [EC:2.7.7.7] 
D      556571 primpol; DNA-directed primase/polymerase protein	K22761 PRIMPOL; DNA-directed primase/polymerase protein [EC:2.7.7.102 2.7.7.7] 
C    Nucleases
D      324964 dclre1a; DNA cross-link repair 1A protein	K15340 DCLRE1A; DNA cross-link repair 1A protein 
D      768137 dclre1b; 5' exonuclease Apollo	K15341 DCLRE1B; DNA cross-link repair 1B protein [EC:3.1.-.-] 
D      641427 exo5; exonuclease V	K17815 EXO5; exonuclease V [EC:3.1.-.-] 
D      553237 zranb3; DNA annealing helicase and endonuclease ZRANB3	K25861 ZRANB3; DNA annealing helicase and endonuclease ZRANB3 [EC:5.6.2.- 3.1.-.-] 
D      406563 zgc:85936; ankyrin repeat and LEM domain-containing protein 1	K21411 ANKLE1; ankyrin repeat and LEM domain-containing protein 1 
C    Helicases
D      562952 helq; helicase POLQ-like	K19178 HELQ; POLQ-like helicase [EC:5.6.2.4] 
D      553504 ercc6l2; DNA excision repair protein ERCC-6-like 2	K20098 ERCC6L2; DNA excision repair protein ERCC-6-like 2 [EC:5.6.2.-] 
C    PSO4 complex
D      321544 prpf19; pre-mRNA-processing factor 19	K10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27] 
D      394059 cdc5l; cell division cycle 5-like protein	K12860 CDC5L; pre-mRNA-splicing factor CDC5/CEF1 
D      493614 bcas2; pre-mRNA-splicing factor SPF27	K12861 BCAS2; pre-mRNA-splicing factor SPF27 
D      100004402 plrg1; pleiotropic regulator 1	K12862 PLRG1; pleiotropic regulator 1 
C    Modulation of nucleotide pools
D      415197 nudt15; nucleotide triphosphate diphosphatase NUDT15 isoform 2	K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] 
D      406727 nudt1; oxidized purine nucleoside triphosphate hydrolase	K17816 NUDT1; 8-oxo-dGTP diphosphatase / 2-hydroxy-dATP diphosphatase [EC:3.6.1.55 3.6.1.56] 
D      550541 nudt18; 8-oxo-dGDP phosphatase NUDT18	K17817 NUDT18; 8-oxo-dGDP phosphatase [EC:3.6.1.58] 
D      449835 dut; deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial	K01520 dut; dUTP diphosphatase [EC:3.6.1.23] 
D      110438480 deoxyuridine 5'-triphosphate nucleotidohydrolase-like	K01520 dut; dUTP diphosphatase [EC:3.6.1.23] 
D      30740 rrm1; ribonucleoside-diphosphate reductase large subunit	K10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1] 
D      30733 rrm2; ribonucleoside-diphosphate reductase subunit M2	K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1] 
D      100330864 ribonucleoside-diphosphate reductase subunit M2 isoform 1	K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1] 
D      368909 rrm2b; ribonucleoside-diphosphate reductase subunit M2 B	K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1] 
#
A<b>Prokaryotic type</b>
B  SSBR (single strand breaks repair)
C    Direct repair
D      553368 mgmt; methylated-DNA--protein-cysteine methyltransferase isoform 1	K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63] 
D      394039 cpdp; CPD photolyase	K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3] 
C    BER (base exicision repair)
D      DNA glycosylases
E        393949 unga; uracil DNA glycosylase a	K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27] 
E        571301 ungb; uracil-DNA glycosylase	K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27] 
E        570901 smug1; single-strand-selective monofunctional uracil-DNA glycosylase 1	K10800 SMUG1; single-strand selective monofunctional uracil DNA glycosylase [EC:3.2.2.-] 
E        566516 mpg; DNA-3-methyladenine glycosylase	K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21] 
E        558403 mutyh; adenine DNA glycosylase	K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31] 
E        100008368 nthl1; endonuclease III-like protein 1	K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] 
D      AP endonucleases
D      RecJ
D      DNA ligase
D      DNA polymerase I
C    NER (nucleotide excision repair)
D      GGR (global genome repair) factors
D      TCR (transcription coupled repair) factors
E        DNA-directed RNA polymerase complex (RNAP)
E        TRCF (transcription-repair coupling factor)
C    MMR (mismatch excision repair)
D      Mismatch and loop recognition factors
D      Molecular matchmaker
D      Strand discrimination factor
D      DNA exonucleases
D      DNA polymerase III holoenzyme
D      DNA ligase
D      Other MMR factors
E        550504 ssbp1; single-stranded DNA-binding protein, mitochondrial	K03111 ssb; single-strand DNA-binding protein 
B  DSBR (double strand breaks repair)
C    HR (homologous recombination)
D      RecBC pathway proteins
D      RecFOR pathway proteins
D      AddAB pathway proteins
D      Other HR factor
D      Archaeal homologous recombinant proteins
C    NHEJ (non-homologous end-joining)
D      Two-component NHEJ DNA repair complex
D      SHIIR (short-homology-independent illegitimate recombination)
E        Facilitator
E        Supressor
D      SHDIR (short-homology-dependent illegitimate recombination)
E        RecET pathway
E        Facilitator
E        Supressor
B  TLS (translesion DNA synthesis) factors
C    Y-family DNA polymerases
C    Other SOS response factors
D      550504 ssbp1; single-stranded DNA-binding protein, mitochondrial	K03111 ssb; single-strand DNA-binding protein 
B  Other factors with a suspected DNA repair function
C    DNA polymerase
C    DNA helicases
C    Modulation of nucleotide pools
D      415197 nudt15; nucleotide triphosphate diphosphatase NUDT15 isoform 2	K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] 
D      449835 dut; deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial	K01520 dut; dUTP diphosphatase [EC:3.6.1.23] 
D      110438480 deoxyuridine 5'-triphosphate nucleotidohydrolase-like	K01520 dut; dUTP diphosphatase [EC:3.6.1.23] 
C    Others
!
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#Last updated: March 29, 2024