+C Two-component system KO
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Two-Component System - Desulfosarcina widdelii
%
!
AOmpR family
B PhoR-PhoB (phosphate starvation response)
C DSCW_58580 phoR; PAS domain-containing sensor histidine kinase K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]
C DSCW_13640 hypothetical protein K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]
C DSCW_42080 hypothetical protein K07658 phoB1; two-component system, OmpR family, alkaline phosphatase synthesis response regulator PhoP
C DSCW_58570 drrA; DNA-binding response regulator K07658 phoB1; two-component system, OmpR family, alkaline phosphatase synthesis response regulator PhoP
C DSCW_09860 hypothetical protein K07658 phoB1; two-component system, OmpR family, alkaline phosphatase synthesis response regulator PhoP
C DSCW_53820 DNA-binding response regulator K07658 phoB1; two-component system, OmpR family, alkaline phosphatase synthesis response regulator PhoP
B SenX3-RegX3 (phosphate starvation response)
B PhoQ-PhoP (magnesium transport)
B EnvZ-OmpR (osmotic stress response)
B RstB-RstA
C DSCW_26750 DNA-binding response regulator K07661 rstA; two-component system, OmpR family, response regulator RstA
B CpxA-CpxR (envelope stress response)
C DSCW_16830 hypothetical protein K07662 cpxR; two-component system, OmpR family, response regulator CpxR
B CssS-CssR (secretion stress response)
B CreC-CreB (phosphate regulation)
C DSCW_39870 creC; sensor histidine kinase K07641 creC; two-component system, OmpR family, sensor histidine kinase CreC [EC:2.7.13.3]
C DSCW_39860 creB; DNA-binding response regulator K07663 creB; two-component system, OmpR family, catabolic regulation response regulator CreB
B BaeS-BaeR (envelope stress response)
B BasS-BasR (antimicrobial peptide resistance)
B CusS-CusR (copper tolerance)
B QseC-QseB (quorum sensing)
B KdpD-KdpE (potassium transport)
B TorS-TorR (TMAO respiration)
B ArcB-ArcA (anoxic redox control)
B TctE-TctD (tricarboxylic acid transport)
B ResE-ResD (aerobic and anaerobic respiration)
B VicK-VicR (cell wall metabolism)
B MprB-MprA (maintenance of persistent infection)
B MtrB-MtrA (osmotic stress response)
B PrrB-PrrA (intracellular multiplication)
B TrcS-TrcR
B NrsS-NrsR (nickel tolerance)
B ManS-ManR (manganese homeostasis)
B NblS-NblR (photosynthesis)
B SasA-RpaAB (circadian timing mediating)
B SaeS-SaeR (staphylococcal virulence regulation)
B BceS-BceR (bacitracin transport)
B BraS-BraR (bacitracin transport)
B GraS-GraR (cationic antimicrobial peptide transport)
B YxdK-YxdJ (antimicrobial peptide response)
B ChvG-ChvI (acidity sensing)
B CiaH-CiaR
B ParS-ParR (polymyxin-adaptive resistance)
B AdeS-AdeR
B VanS-VanR (VanB type vancomycin resistance)
B VanS-VanR (VanE type vancomycin resistance)
B VanS-VanR (actinomycete type vancomycin resistance)
B ArlS-ArlR (virulence regulation)
B Ihk-Irr (virulence regulation)
B PfeS-PfeR (enterobactin-dependent iron acquisition)
B NisK-NisR (lantibiotic biosynthesis)
B Unclassified
C DSCW_65850 hypothetical protein K02483 K02483; two-component system, OmpR family, response regulator
C DSCW_02920 DNA-binding response regulator K02483 K02483; two-component system, OmpR family, response regulator
C DSCW_16880 hypothetical protein K02483 K02483; two-component system, OmpR family, response regulator
C DSCW_24850 response regulator K02483 K02483; two-component system, OmpR family, response regulator
C DSCW_65200 two-component system response regulator K02483 K02483; two-component system, OmpR family, response regulator
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ANarL family
B NarX-NarL (nitrate respiration)
B NarQ-NarP (nitrate respiration)
B UhpB-UhpA (hexose phosphates uptake)
B FusK-FusR (virulence regulation)
B RcsC-RcsD-RcsB (capsule synthesis)
B BarA-UvrY (central carbon metabolism)
C DSCW_41750 DNA-binding response regulator K07689 uvrY; two-component system, NarL family, invasion response regulator UvrY
C DSCW_63140 DNA-binding response regulator K07689 uvrY; two-component system, NarL family, invasion response regulator UvrY
B ComP-ComA (competence)
B EvgS-EvgA (acid and drug tolerance)
B DegS-DegU (multicellular behavior control)
B DesK-DesR (membrane lipid fluidity regulation)
B VraS-VraR (cell-wall peptidoglycan synthesis)
B LiaS-LiaR (cell wall stress response)
B DevS-DevR (redox response)
B NreB-NreC (dissimilatory nitrate/nitrite reduction)
B YdfH-YdfI
B SalK-SalR
B PprA–PprB (biofilm formation)
B Unclassified
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ASpo family
B KinABCDE-Spo0FA (sporulation control)
C DSCW_18840 hypothetical protein K13533 kinE; two-component system, sporulation sensor kinase E [EC:2.7.13.3]
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ACitB family
B CitA-CitB (citrate fermentation)
B CitS-CitT (magnesium-citrate transport)
B DcuS-DcuR (C4-dicarboxylate metabolism)
B DctS-DctR (C4-dicarboxylate transport)
B MalK-MalR (malate transport)
B Unclassified
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ALytTR family
B LysS-LysR
B AlgZ-AlgR (alginate production)
B NatK-NatR (sodium extrusion)
B AgrC-AgrA (exoprotein synthesis)
B AgrC2-AgrA2 (virulence regulation)
B ComD-ComE (competence)
B Unclassified
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ANtrC family
B GlnL-GlnG (nitrogen regulation)
B NtrY-NtrX (nitrogen regulation)
C DSCW_38650 PAS domain-containing sensor histidine kinase K13598 ntrY; two-component system, NtrC family, nitrogen regulation sensor histidine kinase NtrY [EC:2.7.13.3]
C DSCW_38660 sigma-54-dependent Fis family transcriptional regulator K13599 ntrX; two-component system, NtrC family, nitrogen regulation response regulator NtrX
B HydH-HydG (metal tolerance)
C DSCW_48570 hypothetical protein K07709 zraS; two-component system, NtrC family, sensor histidine kinase HydH [EC:2.7.13.3]
C DSCW_13570 zraS_1; PAS domain-containing sensor histidine kinase K07709 zraS; two-component system, NtrC family, sensor histidine kinase HydH [EC:2.7.13.3]
C DSCW_47680 zraS_2; PAS domain-containing sensor histidine kinase K07709 zraS; two-component system, NtrC family, sensor histidine kinase HydH [EC:2.7.13.3]
C DSCW_47880 zraS_3; PAS domain-containing sensor histidine kinase K07709 zraS; two-component system, NtrC family, sensor histidine kinase HydH [EC:2.7.13.3]
C DSCW_48560 acetoacetate metabolism regulatory protein AtoC K07713 zraR; two-component system, NtrC family, response regulator HydG
C DSCW_13580 acetoacetate metabolism regulatory protein AtoC K07713 zraR; two-component system, NtrC family, response regulator HydG
C DSCW_47690 acetoacetate metabolism regulatory protein AtoC K07713 zraR; two-component system, NtrC family, response regulator HydG
C DSCW_47890 acetoacetate metabolism regulatory protein AtoC K07713 zraR; two-component system, NtrC family, response regulator HydG
C DSCW_16920 sigma-54-dependent Fis family transcriptional regulator K07713 zraR; two-component system, NtrC family, response regulator HydG
C DSCW_42270 hypothetical protein K07713 zraR; two-component system, NtrC family, response regulator HydG
C DSCW_42480 hypothetical protein K07713 zraR; two-component system, NtrC family, response regulator HydG
C DSCW_29820 sigma-54-dependent Fis family transcriptional regulator K07713 zraR; two-component system, NtrC family, response regulator HydG
C DSCW_56670 sigma-54-dependent Fis family transcriptional regulator K07713 zraR; two-component system, NtrC family, response regulator HydG
C DSCW_42100 hypothetical protein K07713 zraR; two-component system, NtrC family, response regulator HydG
B AtoS-AtoC (cPHB biosynthesis)
C DSCW_09320 sigma-54-dependent Fis family transcriptional regulator K07714 atoC; two-component system, NtrC family, response regulator AtoC
C DSCW_42010 ntrC1; sigma-54-dependent Fis family transcriptional regulator K07714 atoC; two-component system, NtrC family, response regulator AtoC
C DSCW_61190 sigma-54-dependent Fis family transcriptional regulator K07714 atoC; two-component system, NtrC family, response regulator AtoC
C DSCW_55400 acetoacetate metabolism regulatory protein AtoC K07714 atoC; two-component system, NtrC family, response regulator AtoC
C DSCW_62150 acetoacetate metabolism regulatory protein AtoC K07714 atoC; two-component system, NtrC family, response regulator AtoC
C DSCW_30080 Fis family transcriptional regulator K07714 atoC; two-component system, NtrC family, response regulator AtoC
C DSCW_03370 hypothetical protein K07714 atoC; two-component system, NtrC family, response regulator AtoC
B PilS-PilR (type 4 fimbriae synthesis)
C DSCW_06770 pilR; acetoacetate metabolism regulatory protein AtoC K02667 pilR; two-component system, NtrC family, response regulator PilR
B GlrK-GlrR (amino sugar metabolism)
B PgtB-PgtA (phosphoglycerate transport)
B DctB-DctD (C4-dicarboxylate transport)
B KinB-AlgB (alginate production)
C DSCW_36240 PAS domain-containing sensor histidine kinase K11383 kinB; two-component system, NtrC family, sensor histidine kinase KinB [EC:2.7.13.3]
C DSCW_36250 algB; alginate biosynthesis transcriptional regulatory protein AlgB K11384 algB; two-component system, NtrC family, response regulator AlgB
B HupT-HupR (hydrogenase synthesis regulation)
B Unclassified
C DSCW_41650 hypothetical protein K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C DSCW_16870 two-component sensor histidine kinase K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C DSCW_16910 two-component sensor histidine kinase K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C DSCW_24830 two-component sensor histidine kinase K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C DSCW_37150 hypothetical protein K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C DSCW_60700 hypothetical protein K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C DSCW_60990 hypothetical protein K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C DSCW_61200 hypothetical protein K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C DSCW_28660 hypothetical protein K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C DSCW_39930 sensor histidine kinase K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C DSCW_39970 two-component sensor histidine kinase K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C DSCW_39990 two-component sensor histidine kinase K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C DSCW_64040 hypothetical protein K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C DSCW_65230 two-component sensor histidine kinase K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C DSCW_65270 two-component sensor histidine kinase K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C DSCW_65340 two-component sensor histidine kinase K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C DSCW_09160 hypothetical protein K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
#
ACheA family
B CheA-CheYBV (chemotaxis)
C DSCW_65890 hypothetical protein K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
C DSCW_21800 hypothetical protein K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
C DSCW_66560 hypothetical protein K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
C DSCW_42670 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C DSCW_35000 cheY34H-2; response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C DSCW_66550 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C DSCW_57550 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C DSCW_65870 cheB; chemotaxis response regulator protein-glutamate methylesterase K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
C DSCW_66530 chemotaxis response regulator protein-glutamate methylesterase K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
C DSCW_66570 hypothetical protein K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
B ChpA-ChpB/PilGH (chemosensory)
B PixL-PixGH (positive phototaxis)
B WspE-WspRF (chemosensory)
B Cph1-Rcp1 (light response)
#
ACell cycle family
B PleC-PleD (cell fate control)
C DSCW_46310 response regulator K11443 divK; two-component system, cell cycle response regulator DivK
B CckA-CtrA/CpdR (cell cycle control)
C DSCW_17510 hypothetical protein K13587 cckA; two-component system, cell cycle sensor histidine kinase and response regulator CckA [EC:2.7.13.3]
C DSCW_17530 hypothetical protein K13587 cckA; two-component system, cell cycle sensor histidine kinase and response regulator CckA [EC:2.7.13.3]
C DSCW_17670 hypothetical protein K13587 cckA; two-component system, cell cycle sensor histidine kinase and response regulator CckA [EC:2.7.13.3]
C DSCW_47020 hypothetical protein K13587 cckA; two-component system, cell cycle sensor histidine kinase and response regulator CckA [EC:2.7.13.3]
C DSCW_47100 hypothetical protein K13587 cckA; two-component system, cell cycle sensor histidine kinase and response regulator CckA [EC:2.7.13.3]
C DSCW_32530 hypothetical protein K13587 cckA; two-component system, cell cycle sensor histidine kinase and response regulator CckA [EC:2.7.13.3]
C DSCW_32540 hypothetical protein K13587 cckA; two-component system, cell cycle sensor histidine kinase and response regulator CckA [EC:2.7.13.3]
C DSCW_22720 hypothetical protein K13587 cckA; two-component system, cell cycle sensor histidine kinase and response regulator CckA [EC:2.7.13.3]
C DSCW_25410 hypothetical protein K13587 cckA; two-component system, cell cycle sensor histidine kinase and response regulator CckA [EC:2.7.13.3]
C DSCW_54590 hypothetical protein K13587 cckA; two-component system, cell cycle sensor histidine kinase and response regulator CckA [EC:2.7.13.3]
C DSCW_55330 hypothetical protein K13587 cckA; two-component system, cell cycle sensor histidine kinase and response regulator CckA [EC:2.7.13.3]
C DSCW_29900 hypothetical protein K13587 cckA; two-component system, cell cycle sensor histidine kinase and response regulator CckA [EC:2.7.13.3]
C DSCW_63110 hypothetical protein K13587 cckA; two-component system, cell cycle sensor histidine kinase and response regulator CckA [EC:2.7.13.3]
C DSCW_53260 hypothetical protein K13587 cckA; two-component system, cell cycle sensor histidine kinase and response regulator CckA [EC:2.7.13.3]
C DSCW_02940 hypothetical protein K13587 cckA; two-component system, cell cycle sensor histidine kinase and response regulator CckA [EC:2.7.13.3]
C DSCW_03260 hypothetical protein K13587 cckA; two-component system, cell cycle sensor histidine kinase and response regulator CckA [EC:2.7.13.3]
C DSCW_08170 hypothetical protein K13587 cckA; two-component system, cell cycle sensor histidine kinase and response regulator CckA [EC:2.7.13.3]
C DSCW_50110 hypothetical protein K13589 cpdR; two-component system, cell cycle response regulator CpdR
B Hk1-Rrp1 (glycerol uptake and utilization)
#
ALux family
B LuxQN/CqsS-LuxU-LuxO (quorum sensing)
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ALuxR family
B DctS-DctR (C4-dicarboxylate transport)
B TtrS-TtrR (tetrathionate respiration)
B FixL-FixJ (nitrogen fixation)
B SsrA-SsrB
#
AOther families
B FlrB-FlrC (polar flagellar synthesis)
B AauS-AauR (acidic amino acids utilization)
B SLN1-YPD1-SSK1/SKN7 (osmosensing)
B RpfC-RpfG (cell-to-cell signaling)
B GlnK-GlnL (glutamine utilization)
B HspS-HspR (hexose phosphates uptake)
B YesM-YesN
B CikA
B RegB-RegA (redox response)
C DSCW_40000 response regulator K15012 regA; two-component system, response regulator RegA
B FitF-FitH (insecticidal toxin regulation)
B PhcS-PhcRQ
B SagS-HptB-HsbR (swarming activity and biofilm formation)
C DSCW_47710 hypothetical protein K20976 hptB; histidine phosphotransfer protein HptB
B PdtaS-PdtaR
C DSCW_24760 hypothetical protein K22010 pdtaR; two-component system, response regulator PdtaR
C DSCW_44750 hypothetical protein K22010 pdtaR; two-component system, response regulator PdtaR
C DSCW_56890 hypothetical protein K22010 pdtaR; two-component system, response regulator PdtaR
B NasS-NasT
B Unclassified
C DSCW_47700 hypothetical protein K11527 K11527; two-component system, sensor histidine kinase and response regulator [EC:2.7.13.3]
C DSCW_35010 hybrid sensor histidine kinase/response regulator K11527 K11527; two-component system, sensor histidine kinase and response regulator [EC:2.7.13.3]
C DSCW_64910 hypothetical protein K11527 K11527; two-component system, sensor histidine kinase and response regulator [EC:2.7.13.3]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: December 14, 2023