+E Messenger RNA Biogenesis KO
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Messenger RNA Biogenesis - Escherichia coli K-12 BW2952
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AEukaryotic type
B mRNA processing factors
C 5' end processing
D Capping factors
D Cap binding complex
C 3' end processing
D Pre-mRNA cleavage factor Im (CFIm)
D Pre-mRNA cleavage factor IIm (CFIIm)
D Cleavage and polyadenylation specificity factor (CPSF) complex
D Cleavage stimulation factor (CSTF) complex
D U7-dependent histone pre-mRNA processing factors
D DRB sensitivity inducing factor (DSIF) complex
D N6-methyltransferase complex
D Poly(A) addition factors
D Negative regulators of mRNA 3' end processing
C Other processing factors
B mRNA surveillance and transport factors
C Transport factors
D EJC complex
D TREX complex
D TREX-2 complex
D Nuclear pore complex
D Ran-mediated transport factors
D eIF4F and regulatory proteins
D APOBEC1-ACF complex
D Other transport factors
C Surveillance factors
D Surveillance complex
D Protein phosphatase 2A
D Other surveillance factors
C Factors involved in mRNA localization
D Cargo complex
D Factors that have mRNA localization signals
D Trans-acting binding proteins
D Other mRNA localization factors
C mRNA cycle factors
D Common to processing body (P body) and stress granule
D P-body specific factors
D Stress granule specific factors
B mRNA degradation factors
C 5'-3' decay
D Decapping complex
D Lsm complex
D 5' exonucleases
D Other 5'-3' decay factors
C 3'-5' decay
D Core exosome factors
D Exosome cofactors
D TRAMP complex
D Ski complex
D Ccr4-NOT complex
D Pan complex
D Other 3'-5' decay factors
C Other degradation factors
D RNases
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AProkaryotic type
B Bacterial mRNA degradation factors
C RNA degradosome components
D Ribonucreases
E BWG_0932 rne; fused ribonucleaseE: endoribonuclease/RNA-binding protein/RNA degradosome binding protein K08300 rne; ribonuclease E [EC:3.1.26.12]
E BWG_2947 rng; ribonuclease G K08301 rng; ribonuclease G [EC:3.1.26.-]
E BWG_2331 rnc; RNase III K03685 rnc; ribonuclease III [EC:3.1.26.3]
E BWG_3891 rnr; exoribonuclease R, RNase R K12573 rnr; ribonuclease R [EC:3.1.13.1]
E BWG_3877 orn; oligoribonuclease K13288 orn; oligoribonuclease [EC:3.1.-.-]
D Helicases
E BWG_3463 rhlB; ATP-dependent RNA helicase K03732 rhlB; ATP-dependent RNA helicase RhlB [EC:5.6.2.7]
E BWG_0650 rhlE; RNA helicase K11927 rhlE; ATP-dependent RNA helicase RhlE [EC:5.6.2.7]
E BWG_2866 deaD; ATP-dependent RNA helicase K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7]
E BWG_3500 recQ; ATP-dependent DNA helicase K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
D Other RNA degradosome components
E BWG_2514 eno; enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
E BWG_2868 pnp; polynucleotide phosphorylase/polyadenylase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
E BWG_3465 rho; transcription termination factor K03628 rho; transcription termination factor Rho
E BWG_3585 pfkA; 6-phosphofructokinase I K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
C Other RNA degradation factors
D Chaperones
E BWG_0013 dnaK; chaperone Hsp70, co-chaperone with DnaJ K04043 dnaK; molecular chaperone DnaK
E BWG_3856 groL; Cpn60 chaperonin GroEL, large subunit of GroESL K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
E BWG_3884 hfq; HF-I, host factor for RNA phage Q beta replication K03666 hfq; host factor-I protein
D Others
E BWG_2265 ppk; polyphosphate kinase, component of RNA degradosome K00937 ppk1; polyphosphate kinase [EC:2.7.4.1]
E BWG_0136 pcnB; poly(A) polymerase I K00970 pcnB; poly(A) polymerase [EC:2.7.7.19]
E BWG_2565 rppH; nucleotide hydrolase K08311 nudH; putative (di)nucleoside polyphosphate hydrolase [EC:3.6.1.-]
E BWG_2432 csrA; pleiotropic regulatory protein for carbon source metabolism K03563 csrA; carbon storage regulator
E BWG_2952 csrD; conserved inner membrane protein K18765 csrD; RNase E specificity factor CsrD
E BWG_3598 rraA; ribonuclease E (RNase E) inhibitor protein K02553 rraA; regulator of ribonuclease activity A
E BWG_3961 rraB; conserved protein K09893 rraB; regulator of ribonuclease activity B
E BWG_2907 yhbJ; predicted protein with nucleoside triphosphate hydrolase domain K06958 rapZ; RNase adapter protein RapZ
E BWG_1240 hrpA; ATP-dependent helicase K03578 hrpA; ATP-dependent RNA helicase HrpA [EC:5.6.2.6]
E BWG_0141 hrpB; predicted ATP-dependent helicase K03579 hrpB; ATP-dependent RNA helicase HrpB [EC:5.6.2.6]
D Bacterial Small RNA Regulators
E BWG_4230 dsrA; Regulatory sRNA enhances translation of RpoS; component of acid resistance regulatory circuit; also antagonist of H-NS function by decreasing H-NS levels K18502 dsrA; small regulatory RNA DsrA
E BWG_4212 sroB; Novel sRNA, function unknown K18503 chiX; small regulatory RNA ChiX
E BWG_4254 ryhA; Novel sRNA, function unknown K18504 arcZ; small regulatory RNA ArcZ
E BWG_4238 glmY; sRNA activator of glmS mRNA K15841 glmY; small regulatory RNA GlmY
E BWG_4259 glmZ; sRNA activator of glmS mRNA, Hfq-dependent K18505 glmZ; small regulatory RNA GlmZ
E BWG_4209 sgrS; sRNA that destabilzes ptsG mRNA; regulated by sgrR K18506 sgrS; small regulatory RNA SgrS
E BWG_4255 ryhB; Regulatory sRNA mediating positive Fur regulon response; requires Hfq for function; global iron regulator; degraded by RNase E when bound to target K18507 ryhB; small regulatory RNA RyhB
E BWG_4214 rybB; sRNA effector of ompC and ompW mRNA instability; requires Hfq K18508 rybB; small regulatory RNA RybB
E BWG_4222 rydC; sRNA regulator of yejABEF K18509 rydC; small regulatory RNA RydC
E BWG_4242 micA; sRNA effector of ompA mRNA instability in stationary phase; requires Hfq K18511 micA; small regulatory RNA MicA
E BWG_4221 micC; MicC sRNA regulator of OmpC translation K18512 micC; small regulatory RNA MicC
E BWG_4236 micF; Regulatory antisense sRNA affecting ompF expression; member of soxRS regulon K18513 micF; small regulatory RNA MicF
E BWG_4243 csrB; CsrA-binding sRNA, antagonizing CsrA regulation; blocks the CsrA binding of glgC mRNA K18515 csrB; small regulatory RNA CsrB
E BWG_4261 csrC; CsrC sRNA sequesters CsrA, a carbon flux regulator; also affects biofilms and motilty K18516 csrC; small regulatory RNA CsrC
E BWG_4224 dicF; DicF antisense sRNA, inhibits ftsZ, Qin prophage K18517 dicF; small regulatory RNA DicF
E BWG_4226 rprA; Positive regulatory sRNA for RpoS translation; non-essential gene K18518 rprA; small regulatory RNA RprA
E BWG_4231 rseX; sRNA regulating ompA and ompC translation, with Hfq K18519 rseX; small regulatory RNA RseX
E BWG_4235 ryeE; Novel sRNA, function unknown, prophage remnant PR-X hybrid K18520 cyaR; small regulatory RNA CyaR
E BWG_4244 gcvB; GcvB sRNA gene divergent from gcvA K18521 gcvB; small regulatory RNA GcvB
E BWG_4245 omrA; sRNA down regulates OM proteins; positively regulated by OmpR/EnvZ; binds Hfq K18522 omrA; small regulatory RNA OmrA
E BWG_4246 omrB; sRNA down regulates OM proteins; positively regulated by OmpR/EnvZ; binds Hfq K18523 omrB; small regulatory RNA OmrB
E BWG_4256 gadY; sRNA regulator of gadAB transcriptional activator GadX mRNA K18525 gadY; small regulatory RNA GadY
E BWG_4258 istR; sRNAs IstR-1 and IstR-2, tisB regulators K18526 istR; sRNA antisense regulator of TisB protein
E BWG_4260 spf; Spot 42 sRNA; antisense regulator of galK translation K18527 spf; small regulatory RNA Spot 42
E BWG_4262 oxyS; OxyS sRNA activates genes that detoxify oxidative damage K18528 oxyS; small regulatory RNA OxyS
B Archeal mRNA degradation factors
C Exosome components
D Core exosome
D Cofactors
D Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: April 25, 2024