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Transfer RNA Biogenesis - Escherichia coli O7:K1 IAI39 (ExPEC)
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AEukaryotic type
B 5'processing factors
C Ribonucrease P
B 3'processing and CCA adding factors
C 3'processing factors
D ECIAI39_2416 elaC; binuclear zinc phosphodiesterase K00784 rnz; ribonuclease Z [EC:3.1.26.11]
C CCA adding factors
D ECIAI39_3552 cca; fused tRNA nucleotidyl transferase; 2'3'-cyclic phosphodiesterase and 2'nucleotidase and phosphatase K00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]
B tRNA spricing factors
C tRNA splicing endonuclease complex
C tRNA splicing ligase complex
D ECIAI39_3901 rtcB; conserved hypothetical protein K14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8]
C Other tRNA splicing factors
B tRNA transport factors
C tRNA export factors
C tRNA import factors
B Aminoacyl-tRNA synthetases (AARSs)
C Multi-aminoacyl-tRNA synthetase complex (MSC)
D ECIAI39_2546 gltX; glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D ECIAI39_0449 proS; prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D ECIAI39_0027 ileS; isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D ECIAI39_0617 leuS; leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D ECIAI39_0902 metG; methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D ECIAI39_0637 glnS; glutamyl-tRNA synthetase K01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18]
D ECIAI39_1173 argS; arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D ECIAI39_4557 lysU; lysine tRNA synthetase, inducible K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D ECIAI39_3306 lysS; lysine tRNA synthetase, constitutive K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D ECIAI39_1183 aspS; aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
C Other AARSs
D ECIAI39_2882 alaS; alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D ECIAI39_2217 asnS; asparaginyl tRNA synthetase K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]
D ECIAI39_1335 thrS; threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D ECIAI39_2255 serS; seryl-tRNA synthetase, also charges selenocysteinyl-tRNA with serine K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D ECIAI39_0491 cysS; cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D ECIAI39_4731 valS; valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D ECIAI39_2715 hisS; histidyl tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D ECIAI39_1339 pheS; phenylalanine tRNA synthetase, alpha subunit K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D ECIAI39_1340 pheT; phenylalanine tRNA synthetase, beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D ECIAI39_1418 tyrS; tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D ECIAI39_3862 trpS; tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
C Trans-editing factors
D ECIAI39_3113 dtd; D-tyr-tRNA(Tyr) deacylase K07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
C AARS associated factors
D ECIAI39_2057 hinT; purine nucleoside phosphoramidase K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
B tRNA modification factors
C Deaminases
C Dihydorouridine synthases
C Methylthiotransferase
C Methyltransferases
D ECIAI39_3384 yggH; tRNA (m7G46) methyltransferase, SAM-dependent K03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]
D ECIAI39_0448 yaeB; conserved hypothetical protein K22900 TRMO; tRNA (adenine37-N6)-methyltransferase [EC:2.1.1.-]
C Psudouridine synthases
D ECIAI39_2467 truA; pseudouridylate synthase I K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D ECIAI39_3663 truB; tRNA pseudouridine synthase K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
D ECIAI39_2934 truD; pseudoruidine synthase K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
C Thiolation factors
D ECIAI39_2731 iscS; cysteine desulfurase (tRNA sulfurtransferase), PLP-dependent K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
C KEOPS/EKC complex
C Elongator complex
C Elongator related proteins
C Other tRNA modification factors
D ECIAI39_3776 yrdC; putative ribosome maturation factor K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D ECIAI39_4636 miaA; delta(2)-isopentenylpyrophosphate tRNA-adenosine transferase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
D ECIAI39_4311 trmE; GTPase K03650 mnmE; tRNA modification GTPase [EC:3.6.-.-]
D ECIAI39_4345 gidA; glucose-inhibited cell-division protein K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme
D ECIAI39_1292 selD; selenophosphate synthase K01008 selD; selenide, water dikinase [EC:2.7.9.3]
B tRNA degradation factors
C TRAMP complex
C Rapid tRNA decay (RTD) pathway factors
D ECIAI39_4686 cysQ; PAPS (adenosine 3'-phosphate 5'-phosphosulfate) 3'(2'),5'-bisphosphate nucleotidase K01082 cysQ; 3'(2'), 5'-bisphosphate nucleotidase [EC:3.1.3.7]
C Other tRNA degradation factors
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AProkaryotic type
B 5'processing factors
C Ribonucrease P
D ECIAI39_4308 rnpA; protein C5 component of RNase P K03536 rnpA; ribonuclease P protein component [EC:3.1.26.5]
D ECIAI39_miscRNA84 RNaseP_bact_a K01978 rnpB; M1 RNA
B 3'processing and CCA adding factors
C 3'processing factors
D ECIAI39_2416 elaC; binuclear zinc phosphodiesterase K00784 rnz; ribonuclease Z [EC:3.1.26.11]
D ECIAI39_1404 rnt; ribonuclease T (RNase T) K03683 rnt; ribonuclease T [EC:3.1.13.-]
D ECIAI39_4162 rph; ribonuclease PH K00989 rph; ribonuclease PH [EC:2.7.7.56]
D ECIAI39_0587 rna; ribonuclease I K01169 rna; ribonuclease I (enterobacter ribonuclease) [EC:4.6.1.21]
D ECIAI39_1628 rnb; ribonuclease II K01147 rnb; exoribonuclease II [EC:3.1.13.1]
D ECIAI39_1249 rnd; ribonuclease D K03684 rnd; ribonuclease D [EC:3.1.13.5]
C CCA adding factors
D ECIAI39_3552 cca; fused tRNA nucleotidyl transferase; 2'3'-cyclic phosphodiesterase and 2'nucleotidase and phosphatase K00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]
B tRNA spricing factors
C tRNA splicing endonucleases
C tRNA splicing ligases
D ECIAI39_3901 rtcB; conserved hypothetical protein K14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8]
C Other tRNA splicing factors
D ECIAI39_0151 ligT; 2'-5' RNA ligase K01975 thpR; RNA 2',3'-cyclic 3'-phosphodiesterase [EC:3.1.4.58]
B tRNA transport factors
C tRNA export factors
D ECIAI39_4924 yjjK; fused putative transporter subunits of ABC superfamily: ATP-binding components K06020 ettA; energy-dependent translational throttle protein EttA
B Aminoacyl-tRNA synthetases (AARSs)
C Multi-aminoacyl-tRNA synthetase complex (MSC)
D ECIAI39_0617 leuS; leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D ECIAI39_0449 proS; prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
C Other AARSs
D ECIAI39_1418 tyrS; tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D ECIAI39_3862 trpS; tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D ECIAI39_1335 thrS; threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D ECIAI39_0027 ileS; isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D ECIAI39_4557 lysU; lysine tRNA synthetase, inducible K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D ECIAI39_3306 lysS; lysine tRNA synthetase, constitutive K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D ECIAI39_2882 alaS; alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D ECIAI39_4731 valS; valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D ECIAI39_0902 metG; methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D ECIAI39_2255 serS; seryl-tRNA synthetase, also charges selenocysteinyl-tRNA with serine K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D ECIAI39_1183 aspS; aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D ECIAI39_4068 glyQ; glycine tRNA synthetase, alpha subunit K01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14]
D ECIAI39_4067 glyS; glycine tRNA synthetase, beta subunit K01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14]
D ECIAI39_0491 cysS; cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D ECIAI39_2546 gltX; glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D ECIAI39_0637 glnS; glutamyl-tRNA synthetase K01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18]
D ECIAI39_1173 argS; arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D ECIAI39_1339 pheS; phenylalanine tRNA synthetase, alpha subunit K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D ECIAI39_1340 pheT; phenylalanine tRNA synthetase, beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D ECIAI39_2715 hisS; histidyl tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D ECIAI39_2217 asnS; asparaginyl tRNA synthetase K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]
D ECIAI39_0148 yadB; glutamyl-Q tRNA(Asp) synthetase K01894 gluQ; glutamyl-Q tRNA(Asp) synthetase [EC:6.1.1.-]
C Trans-editing factors
D ECIAI39_3113 dtd; D-tyr-tRNA(Tyr) deacylase K07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
D ECIAI39_1266 yeaK; conserved hypothetical protein K19055 prdX; Ala-tRNA(Pro) deacylase [EC:3.1.1.-]
B tRNA modification factors
C Deaminases
D ECIAI39_2763 tadA; tRNA-specific adenosine deaminase K11991 tadA; tRNA(adenine34) deaminase [EC:3.5.4.33]
C Dihydorouridine synthases
D ECIAI39_4469 yjbN; tRNA-dihydrouridine synthase A K05539 dusA; tRNA-dihydrouridine synthase A [EC:1.-.-.-]
D ECIAI39_3760 dusB; tRNA-dihydrouridine synthase B K05540 dusB; tRNA-dihydrouridine synthase B [EC:1.-.-.-]
D ECIAI39_2279 dusC; tRNA-dihydrouridine synthase C K05541 dusC; tRNA-dihydrouridine synthase C [EC:1.-.-.-]
C Methylthiotransferases
D ECIAI39_0628 miaB; isopentenyl-adenosine A37 tRNA methylthiolase K06168 miaB; tRNA-2-methylthio-N6-dimethylallyladenosine synthase [EC:2.8.4.3]
C Methyltransferases
D ECIAI39_1179 yecO; AdoMet-dependent methyltransferase K15256 cmoA; tRNA (cmo5U34)-methyltransferase [EC:2.1.1.-]
D ECIAI39_1178 yecP; conserved hypothetical protein K15257 cmoB; tRNA (mo5U34)-methyltransferase [EC:2.1.1.-]
D ECIAI39_2226 smtA; putative AdoMet-dependent methyltransferase K06219 smtA; tRNA 5-carboxymethoxyuridine methyltransferase [EC:2.1.1.-]
D ECIAI39_4935 yjtD; rRNA methyltransferase K02533 lasT; tRNA/rRNA methyltransferase [EC:2.1.1.-]
D ECIAI39_3024 trmA; tRNA (uracil-5-)-methyltransferase K00557 trmA; tRNA (uracil-5-)-methyltransferase [EC:2.1.1.35]
D ECIAI39_3384 yggH; tRNA (m7G46) methyltransferase, SAM-dependent K03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]
D ECIAI39_2811 trmD; tRNA (guanine-1-)-methyltransferase K00554 trmD; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]
D ECIAI39_4311 trmE; GTPase K03650 mnmE; tRNA modification GTPase [EC:3.6.-.-]
D ECIAI39_2789 yfiF; putative methyltransferase K03214 yfiF; RNA methyltransferase, TrmH family [EC:2.1.1.-]
D ECIAI39_4173 trmH; tRNA (Guanosine-2'-O-)-methyltransferase K00556 trmH; tRNA (guanosine-2'-O-)-methyltransferase [EC:2.1.1.34]
D ECIAI39_2733 yfhQ; putative methyltransferase K15396 trmJ; tRNA (cytidine32/uridine32-2'-O)-methyltransferase [EC:2.1.1.200]
D ECIAI39_4127 yibK; putative rRNA methylase K03216 trmL; tRNA (cytidine/uridine-2'-O-)-methyltransferase [EC:2.1.1.207]
D ECIAI39_0448 yaeB; conserved hypothetical protein K22900 TRMO; tRNA (adenine37-N6)-methyltransferase [EC:2.1.1.-]
D ECIAI39_2780 yfiC; putative S-adenosyl-L-methionine-dependent methyltransferase K15460 yfiC; tRNA1Val (adenine37-N6)-methyltransferase [EC:2.1.1.223]
C Psudouridine synthases
D ECIAI39_2467 truA; pseudouridylate synthase I K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D ECIAI39_3663 truB; tRNA pseudouridine synthase K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
D ECIAI39_3213 truC; tRNA pseudouridine synthase K06175 truC; tRNA pseudouridine65 synthase [EC:5.4.99.26]
D ECIAI39_2934 truD; pseudoruidine synthase K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
D ECIAI39_0061 rluA; pseudouridine synthase for 23S rRNA (position 746) and tRNAphe(position 32) K06177 rluA; tRNA pseudouridine32 synthase / 23S rRNA pseudouridine746 synthase [EC:5.4.99.28 5.4.99.29]
C Thiolation factors
D ECIAI39_2004 trmU; tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase K00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]
D ECIAI39_1695 ydaO; putative C32 tRNA thiolase K14058 ttcA; tRNA 2-thiocytidine biosynthesis protein TtcA
D ECIAI39_3951 tusA; sulfurtransferase K04085 tusA; tRNA 2-thiouridine synthesizing protein A [EC:2.8.1.-]
D ECIAI39_3823 tusB; methylsulfur transfer protein K07237 tusB; tRNA 2-thiouridine synthesizing protein B
D ECIAI39_3824 tusC; methylsulfur transfer protein K07236 tusC; tRNA 2-thiouridine synthesizing protein C
D ECIAI39_3825 tusD; methylsulfur transfer protein K07235 tusD; tRNA 2-thiouridine synthesizing protein D [EC:2.8.1.-]
D ECIAI39_2176 tusE; subunit of enzyme for 2-thio modification of mnm5s2U of tRNA anticodon U K11179 tusE; tRNA 2-thiouridine synthesizing protein E [EC:2.8.1.-]
D ECIAI39_2729 iscA; FeS cluster assembly protein K13628 iscA; iron-sulfur cluster assembly protein
D ECIAI39_2731 iscS; cysteine desulfurase (tRNA sulfurtransferase), PLP-dependent K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D ECIAI39_3314 ygfZ; enzyme component involved in 2-methylthio-6-iodeadenosine formation K06980 ygfZ; tRNA-modifying protein YgfZ
C KEOPS/EKC complex
C Other tRNA modification factors
D ECIAI39_4345 gidA; glucose-inhibited cell-division protein K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme
D ECIAI39_4636 miaA; delta(2)-isopentenylpyrophosphate tRNA-adenosine transferase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
D ECIAI39_2473 trmC; fused 5-methylaminomethyl-2-thiouridine-forming enzyme methyltransferase; FAD-dependent demodification enzyme K15461 mnmC; tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein [EC:2.1.1.61 1.5.-.-]
D ECIAI39_0276 queA; S-adenosylmethionine:tRNA ribosyltransferase-isomerase K07568 queA; S-adenosylmethionine:tRNA ribosyltransferase-isomerase [EC:2.4.99.17]
D ECIAI39_0229 queC; queuosine biosynthesis protein K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20]
D ECIAI39_2947 ygcM; 6-pyruvoyl tetrahydrobiopterin synthase (PTPS) K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]
D ECIAI39_2968 ygcF; conserved hypothetical protein K10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3]
D ECIAI39_3216 queF; NADPH-dependent 7-cyano-7-deazaguanine reductase K06879 queF; 7-cyano-7-deazaguanine reductase [EC:1.7.1.13]
D ECIAI39_4630 yjeS; putative Fe-S electron transport protein K18979 queG; epoxyqueuosine reductase [EC:1.17.99.6]
D ECIAI39_1292 selD; selenophosphate synthase K01008 selD; selenide, water dikinase [EC:2.7.9.3]
D ECIAI39_0275 tgt; tRNA-guanine transglycosylase K00773 tgt; queuine tRNA-ribosyltransferase [EC:2.4.2.29]
D ECIAI39_0253 thiI; sulfurtransferase required for thiamine and 4-thiouridine biosynthesis K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]
D ECIAI39_0191 tilS; tRNA(Ile)-lysidine synthetase K04075 tilS; tRNA(Ile)-lysidine synthase [EC:6.3.4.19]
D ECIAI39_2613 ypfI; putative hydrolase K06957 tmcA; tRNA(Met) cytidine acetyltransferase [EC:2.3.1.193]
D ECIAI39_1246 yeaZ; putative peptidase K14742 tsaB; tRNA threonylcarbamoyladenosine biosynthesis protein TsaB
D ECIAI39_3776 yrdC; putative ribosome maturation factor K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D ECIAI39_3560 gcp; O-sialoglycoprotein endopeptidase K25706 tsaD; tRNA N6-adenosine threonylcarbamoyltransferase [EC:2.3.1.234]
D ECIAI39_4632 yjeE; ATPase with strong ADP affinity K06925 tsaE; tRNA threonylcarbamoyladenosine biosynthesis protein TsaE
D ECIAI39_3234 ygdL; conserved hypothetical protein K22132 tcdA; tRNA threonylcarbamoyladenosine dehydratase
B tRNA degradation factors
C ECIAI39_4644 rnr; exoribonuclease R, RNase R K12573 rnr; ribonuclease R [EC:3.1.13.1]
C ECIAI39_3661 pnp; polynucleotide phosphorylase/polyadenylase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: February 29, 2024