+D
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Transfer RNA Biogenesis - Escherichia coli LF82
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AEukaryotic type
B 5'processing factors
C Ribonucrease P
B 3'processing and CCA adding factors
C 3'processing factors
D LF82_1814 rbn; ribonuclease Z K00784 rnz; ribonuclease Z [EC:3.1.26.11]
C CCA adding factors
D LF82_0272 cca; Multifunctional CCA protein K00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]
B tRNA spricing factors
C tRNA splicing endonuclease complex
C tRNA splicing ligase complex
D LF82_2042 rtcB; Protein rtcB K14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8]
C Other tRNA splicing factors
B tRNA transport factors
C tRNA export factors
C tRNA import factors
B Aminoacyl-tRNA synthetases (AARSs)
C Multi-aminoacyl-tRNA synthetase complex (MSC)
D LF82_0888 gltX; glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D LF82_1734 proS; Prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D LF82_1096 iles; Isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D LF82_1186 leuS; Leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D LF82_1322 metG; Methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D LF82_0856 glnS; glutaminyl-tRNA synthetase K01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18]
D LF82_0128 argS; Arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D LF82_1243 lysS; Lysyl-tRNA synthetase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D LF82_1245 lysU; Lysyl-tRNA synthetase, heat inducible K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D LF82_0175 aspS; Aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
C Other AARSs
D LF82_0058 alaS; alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D LF82_0168 asnS; Asparaginyl-tRNA synthetase K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]
D LF82_2262 thrS; Threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D LF82_2118 serS; Seryl-tRNA synthetase, also charges selenocysteinyl-tRNA with serine K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D LF82_0423 cysS; Cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D LF82_2407 valS; Valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D LF82_1011 hisS; Histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D LF82_1638 phes; Phenylalanyl-tRNA synthetase alpha chain K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D LF82_1639 phet; Phenylalanyl-tRNA synthetase beta chain K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D LF82_2342 tyrS; Tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D LF82_2316 trpS; Tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
C Trans-editing factors
D LF82_0530 dtd; D-tyrosyl-tRNA(Tyr) deacylase K07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
C AARS associated factors
D LF82_0995 hinT; HIT-like protein ycfF K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
B tRNA modification factors
C Deaminases
C Dihydorouridine synthases
C Methylthiotransferase
C Methyltransferases
D LF82_2307 trmI; hypothetical protein K03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]
D LF82_2486 yaeB; UPF0066 protein yaeB K22900 TRMO; tRNA (adenine37-N6)-methyltransferase [EC:2.1.1.-]
C Psudouridine synthases
D LF82_2318 truA; tRNA pseudouridine synthase A K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D LF82_2319 truB; tRNA pseudouridine synthase B K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
D LF82_2321 truD; tRNA pseudouridine synthase D K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
C Thiolation factors
D LF82_1122 iscS; cysteine desulfurase (tRNA sulfurtransferase), PLP-dependent K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
C KEOPS/EKC complex
C Elongator complex
C Elongator related proteins
C Other tRNA modification factors
D LF82_1891 rimN; Uncharacterized protein yrdC K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D LF82_1344 miaA; tRNA delta(2)-isopentenylpyrophosphate transferase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
D LF82_1361 mnmE; tRNA modification GTPase trmE K03650 mnmE; tRNA modification GTPase [EC:3.6.-.-]
D LF82_1362 mnmG; tRNA uridine 5-carboxymethylaminomethyl modification K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme
D LF82_2113 selD; selenophosphate synthase K01008 selD; selenide, water dikinase [EC:2.7.9.3]
B tRNA degradation factors
C TRAMP complex
C Rapid tRNA decay (RTD) pathway factors
D LF82_0422 cysQ; Protein cysQ K01082 cysQ; 3'(2'), 5'-bisphosphate nucleotidase [EC:3.1.3.7]
C Other tRNA degradation factors
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AProkaryotic type
B 5'processing factors
C Ribonucrease P
D LF82_1914 rnpA; ribonuclease P protein component K03536 rnpA; ribonuclease P protein component [EC:3.1.26.5]
D LF82_s1915 rnpB; RNase P, M1 sRNA component; involved in transfer RNA and 4.5S RNA-processing K01978 rnpB; M1 RNA
B 3'processing and CCA adding factors
C 3'processing factors
D LF82_1814 rbn; ribonuclease Z K00784 rnz; ribonuclease Z [EC:3.1.26.11]
D LF82_1917 rnt; ribonuclease T K03683 rnt; ribonuclease T [EC:3.1.13.-]
D LF82_1921 rph; ribonuclease PH K00989 rph; ribonuclease PH [EC:2.7.7.56]
D LF82_1905 rna; ribonuclease I K01169 rna; ribonuclease I (enterobacter ribonuclease) [EC:4.6.1.21]
D LF82_1906 rnb; exoribonuclease 2 K01147 rnb; exoribonuclease II [EC:3.1.13.1]
D LF82_1908 rnd; ribonuclease D K03684 rnd; ribonuclease D [EC:3.1.13.5]
C CCA adding factors
D LF82_0272 cca; Multifunctional CCA protein K00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]
B tRNA spricing factors
C tRNA splicing endonucleases
C tRNA splicing ligases
D LF82_2042 rtcB; Protein rtcB K14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8]
C Other tRNA splicing factors
D LF82_1198 ligT; 2'-5' RNA ligase K01975 thpR; RNA 2',3'-cyclic 3'-phosphodiesterase [EC:3.1.4.58]
D LF82_1162 kptA; RNA 2'-phosphotransferase K07559 kptA; putative RNA 2'-phosphotransferase [EC:2.7.1.-]
B tRNA transport factors
C tRNA export factors
D LF82_3498 yjjK; Uncharacterized ABC transporter ATP-binding protein yjjK K06020 ettA; energy-dependent translational throttle protein EttA
B Aminoacyl-tRNA synthetases (AARSs)
C Multi-aminoacyl-tRNA synthetase complex (MSC)
D LF82_1186 leuS; Leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D LF82_1734 proS; Prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
C Other AARSs
D LF82_2342 tyrS; Tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D LF82_2316 trpS; Tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D LF82_2262 thrS; Threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D LF82_1096 iles; Isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D LF82_1243 lysS; Lysyl-tRNA synthetase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D LF82_1245 lysU; Lysyl-tRNA synthetase, heat inducible K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D LF82_0058 alaS; alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D LF82_2407 valS; Valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D LF82_1322 metG; Methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D LF82_2118 serS; Seryl-tRNA synthetase, also charges selenocysteinyl-tRNA with serine K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D LF82_0175 aspS; Aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D LF82_0892 glyQ; glycyl-tRNA synthetase alpha chain K01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14]
D LF82_0893 glyS; glycyl-tRNA synthetase beta chain K01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14]
D LF82_0423 cysS; Cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D LF82_0888 gltX; glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D LF82_0856 glnS; glutaminyl-tRNA synthetase K01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18]
D LF82_0128 argS; Arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D LF82_1638 phes; Phenylalanyl-tRNA synthetase alpha chain K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D LF82_1639 phet; Phenylalanyl-tRNA synthetase beta chain K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D LF82_1011 hisS; Histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D LF82_0168 asnS; Asparaginyl-tRNA synthetase K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]
D LF82_2473 yadB; glutamyl-Q tRNA(Asp) synthetase K01894 gluQ; glutamyl-Q tRNA(Asp) synthetase [EC:6.1.1.-]
C Trans-editing factors
D LF82_0530 dtd; D-tyrosyl-tRNA(Tyr) deacylase K07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
D LF82_2546 ybaK; Uncharacterized protein ybaK K03976 ybaK; Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase [EC:3.1.1.-]
D LF82_2911 yeaK; Uncharacterized protein yeaK K19055 prdX; Ala-tRNA(Pro) deacylase [EC:3.1.1.-]
B tRNA modification factors
C Deaminases
D LF82_2213 tadA; tRNA-specific adenosine deaminase K11991 tadA; tRNA(adenine34) deaminase [EC:3.5.4.33]
C Dihydorouridine synthases
D LF82_0531 dusA; tRNA-dihydrouridine synthase A K05539 dusA; tRNA-dihydrouridine synthase A [EC:1.-.-.-]
D LF82_0532 dusB; tRNA-dihydrouridine synthase B K05540 dusB; tRNA-dihydrouridine synthase B [EC:1.-.-.-]
D LF82_0533 dusC; tRNA-dihydrouridine synthase C K05541 dusC; tRNA-dihydrouridine synthase C [EC:1.-.-.-]
C Methylthiotransferases
D LF82_1345 miaB; UPF0004 protein yleA K06168 miaB; tRNA-2-methylthio-N6-dimethylallyladenosine synthase [EC:2.8.4.3]
C Methyltransferases
D LF82_0324 cmoA; Protein yecO K15256 cmoA; tRNA (cmo5U34)-methyltransferase [EC:2.1.1.-]
D LF82_0325 cmoB; Uncharacterized protein yecP K15257 cmoB; tRNA (mo5U34)-methyltransferase [EC:2.1.1.-]
D LF82_2146 smtA; Protein smtA K06219 smtA; tRNA 5-carboxymethoxyuridine methyltransferase [EC:2.1.1.-]
D LF82_3509 yjtD; Uncharacterized tRNA/rRNA methyltransferase lasT K02533 lasT; tRNA/rRNA methyltransferase [EC:2.1.1.-]
D LF82_2304 trmA; hypothetical protein K00557 trmA; tRNA (uracil-5-)-methyltransferase [EC:2.1.1.35]
D LF82_2307 trmI; hypothetical protein K03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]
D LF82_2305 trmD; trmD tRNA (guanine-1-)-methyltransferase K00554 trmD; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]
D LF82_1361 mnmE; tRNA modification GTPase trmE K03650 mnmE; tRNA modification GTPase [EC:3.6.-.-]
D LF82_3113 yfiF; Uncharacterized tRNA/rRNA methyltransferase yfiF K03214 yfiF; RNA methyltransferase, TrmH family [EC:2.1.1.-]
D LF82_2306 trmH; tRNA guanosine-2'-O-methyltransferase K00556 trmH; tRNA (guanosine-2'-O-)-methyltransferase [EC:2.1.1.34]
D LF82_2308 trmJ; Uncharacterized tRNA/rRNA methyltransferase yfhQ K15396 trmJ; tRNA (cytidine32/uridine32-2'-O)-methyltransferase [EC:2.1.1.200]
D LF82_3349 yibK; Uncharacterized tRNA/rRNA methyltransferase yibK K03216 trmL; tRNA (cytidine/uridine-2'-O-)-methyltransferase [EC:2.1.1.207]
D LF82_2486 yaeB; UPF0066 protein yaeB K22900 TRMO; tRNA (adenine37-N6)-methyltransferase [EC:2.1.1.-]
D LF82_3110 yfiC; Uncharacterized protein yfiC K15460 yfiC; tRNA1Val (adenine37-N6)-methyltransferase [EC:2.1.1.223]
C Psudouridine synthases
D LF82_2318 truA; tRNA pseudouridine synthase A K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D LF82_2319 truB; tRNA pseudouridine synthase B K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
D LF82_2320 truC; tRNA pseudouridine synthase C K06175 truC; tRNA pseudouridine65 synthase [EC:5.4.99.26]
D LF82_2321 truD; tRNA pseudouridine synthase D K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
D LF82_1897 rluA; ribosomal large subunit pseudouridine synthase A K06177 rluA; tRNA pseudouridine32 synthase / 23S rRNA pseudouridine746 synthase [EC:5.4.99.28 5.4.99.29]
C Thiolation factors
D LF82_1359 mnmA; hypothetical protein K00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]
D LF82_2329 ttcA; UPF0021 protein ydaO K14058 ttcA; tRNA 2-thiocytidine biosynthesis protein TtcA
D LF82_2132 sirA; Sulfurtransferase tusA K04085 tusA; tRNA 2-thiouridine synthesizing protein A [EC:2.8.1.-]
D LF82_3274 yhel; Protein tusB K07237 tusB; tRNA 2-thiouridine synthesizing protein B
D LF82_3275 yheM; Protein tusC K07236 tusC; tRNA 2-thiouridine synthesizing protein C
D LF82_3276 yhen; Sulfurtransferase tusD K07235 tusD; tRNA 2-thiouridine synthesizing protein D [EC:2.8.1.-]
D LF82_2691 yccK; Sulfurtransferase tusE K11179 tusE; tRNA 2-thiouridine synthesizing protein E [EC:2.8.1.-]
D LF82_1120 iscA; Iron-binding protein iscA K13628 iscA; iron-sulfur cluster assembly protein
D LF82_1122 iscS; cysteine desulfurase (tRNA sulfurtransferase), PLP-dependent K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D LF82_3181 ygfZ; tRNA-modifying protein ygfZ K06980 ygfZ; tRNA-modifying protein YgfZ
C KEOPS/EKC complex
C Other tRNA modification factors
D LF82_1362 mnmG; tRNA uridine 5-carboxymethylaminomethyl modification K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme
D LF82_1344 miaA; tRNA delta(2)-isopentenylpyrophosphate transferase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
D LF82_1360 mnmC; UPF0209 protein yfcK K15461 mnmC; tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein [EC:2.1.1.61 1.5.-.-]
D LF82_1804 queA; S-adenosylmethionine:tRNA ribosyltransferase-isomerase K07568 queA; S-adenosylmethionine:tRNA ribosyltransferase-isomerase [EC:2.4.99.17]
D LF82_1805 queC; Queuosine biosynthesis protein queC K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20]
D LF82_2179 sscR; 6-pyruvoyl tetrahydrobiopterin synthase K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]
D LF82_3145 ygcF; Uncharacterized protein ygcF K10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3]
D LF82_1806 queF; NadPH-dependent 7-cyano-7-deazaguanine reductase K06879 queF; 7-cyano-7-deazaguanine reductase [EC:1.7.1.13]
D LF82_3456 yjes; electron transport protein yjes K18979 queG; epoxyqueuosine reductase [EC:1.17.99.6]
D LF82_2113 selD; selenophosphate synthase K01008 selD; selenide, water dikinase [EC:2.7.9.3]
D LF82_2560 ybbB; tRNA 2-selenouridine synthase K06917 selU; tRNA 2-selenouridine synthase [EC:2.9.1.3]
D LF82_2245 tgt; Queuine tRNA-ribosyltransferase K00773 tgt; queuine tRNA-ribosyltransferase [EC:2.4.2.29]
D LF82_2252 thiI; Thiamine biosynthesis protein thiI K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]
D LF82_2269 tilS; tRNA(Ile)-lysidine synthase K04075 tilS; tRNA(Ile)-lysidine synthase [EC:6.3.4.19]
D LF82_3626 ypfI; Uncharacterized protein ypfI K06957 tmcA; tRNA(Met) cytidine acetyltransferase [EC:2.3.1.193]
D LF82_2920 yeaZ; M22 peptidase homolog yeaZ K14742 tsaB; tRNA threonylcarbamoyladenosine biosynthesis protein TsaB
D LF82_1891 rimN; Uncharacterized protein yrdC K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D LF82_3224 ygjD; O-sialoglycoprotein endopeptidase K25706 tsaD; tRNA N6-adenosine threonylcarbamoyltransferase [EC:2.3.1.234]
D LF82_3448 yjeE; UPF0079 ATP-binding protein yjeE K06925 tsaE; tRNA threonylcarbamoyladenosine biosynthesis protein TsaE
D LF82_3159 ygdL; Uncharacterized protein ygdL K22132 tcdA; tRNA threonylcarbamoyladenosine dehydratase
B tRNA degradation factors
C LF82_1916 rnr; ribonuclease R K12573 rnr; ribonuclease R [EC:3.1.13.1]
C LF82_1678 pnp; Polyribonucleotide nucleotidyltransferase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: February 29, 2024