+E Messenger RNA Biogenesis KO
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Messenger RNA Biogenesis - Gekko japonicus (Schlegel's Japanese gecko)
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AEukaryotic type
B mRNA processing factors
C 5' end processing
D Capping factors
E 107119718 RNMT; RNA guanine-7 methyltransferase K00565 RNMT; mRNA (guanine-N7-)-methyltransferase [EC:2.1.1.56]
E 107115389 RNGTT; RNA guanylyltransferase and 5'-phosphatase K13917 RNGTT; mRNA-capping enzyme [EC:2.7.7.50 3.6.1.74]
E 107115490 CDK7; cyclin dependent kinase 7 K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
E 107115268 CMTR1; cap methyltransferase 1 K14589 CMTR1; cap1 methyltransferase [EC:2.1.1.57]
E 107109618 CMTR2; cap methyltransferase 2 K14590 CMTR2; cap2 methyltransferase [EC:2.1.1.296]
E 107121426 FAM103A1; family with sequence similarity 103 member A1 K18708 FAM103A1; RNMT-activating mini protein
D Cap binding complex
E 107118360 NCBP1; nuclear cap binding protein subunit 1 K12882 NCBP1; nuclear cap-binding protein subunit 1
E 107108554 nuclear cap-binding protein subunit 2-like K12883 NCBP2; nuclear cap-binding protein subunit 2
E 107119457 nuclear cap-binding protein subunit 2-like K12883 NCBP2; nuclear cap-binding protein subunit 2
C 3' end processing
D Pre-mRNA cleavage factor Im (CFIm)
E 107118986 NUDT21; nudix hydrolase 21 K14397 NUDT21; cleavage and polyadenylation specificity factor subunit 5
E 107105704 CPSF6; cleavage and polyadenylation specific factor 6 K14398 CPSF6_7; cleavage and polyadenylation specificity factor subunit 6/7
E 107121400 CPSF7; cleavage and polyadenylation specific factor 7 K14398 CPSF6_7; cleavage and polyadenylation specificity factor subunit 6/7
D Pre-mRNA cleavage factor IIm (CFIIm)
E 107110661 CLP1; cleavage and polyadenylation factor I subunit 1 K14399 CLP1; polyribonucleotide 5'-hydroxyl-kinase [EC:2.7.1.78]
E 107107642 pre-mRNA cleavage complex 2 protein Pcf11-like K14400 PCF11; pre-mRNA cleavage complex 2 protein Pcf11
D Cleavage and polyadenylation specificity factor (CPSF) complex
E 107124479 CPSF1; cleavage and polyadenylation specific factor 1 K14401 CPSF1; cleavage and polyadenylation specificity factor subunit 1
E 107123849 CPSF2; cleavage and polyadenylation specific factor 2 K14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2
E 107111205 CPSF3; cleavage and polyadenylation specific factor 3 K14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]
E 107116925 CPSF4; cleavage and polyadenylation specific factor 4 K14404 CPSF4; cleavage and polyadenylation specificity factor subunit 4
E 107121836 pre-mRNA 3'-end-processing factor FIP1-like K14405 FIP1L1; pre-mRNA 3'-end-processing factor FIP1
E 107113394 FIP1L1; factor interacting with PAPOLA and CPSF1 K14405 FIP1L1; pre-mRNA 3'-end-processing factor FIP1
E 107123607 WDR33; WD repeat domain 33 K15542 PFS2; polyadenylation factor subunit 2
E 107110849 WDR82; WD repeat domain 82 K14962 WDR82; COMPASS component SWD2
E 107124492 PPP1CB; protein phosphatase 1 catalytic subunit beta K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E 107112146 PPP1CC; protein phosphatase 1 catalytic subunit gamma K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E 107106100 SSU72; SSU72 homolog, RNA polymerase II CTD phosphatase K15544 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16]
D Cleavage stimulation factor (CSTF) complex
E 107112517 CSTF1; cleavage stimulation factor subunit 1 K14406 CSTF1; cleavage stimulation factor subunit 1
E 107124534 CSTF2; cleavage stimulation factor subunit 2 K14407 CSTF2; cleavage stimulation factor subunit 2
E 107109130 CSTF3; cleavage stimulation factor subunit 3 K14408 CSTF3; cleavage stimulation factor subunit 3
E 107109791 SYMPK; symplekin K06100 SYMPK; symplekin
D U7-dependent histone pre-mRNA processing factors
E 107108034 SNRPB; small nuclear ribonucleoprotein polypeptides B and B1 K11086 SNRPB; small nuclear ribonucleoprotein B and B'
E 107115100 SNRPD3; small nuclear ribonucleoprotein D3 polypeptide K11088 SNRPD3; small nuclear ribonucleoprotein D3
E 107107090 SNRPE; small nuclear ribonucleoprotein polypeptide E K11097 SNRPE; small nuclear ribonucleoprotein E
E 107113832 small nuclear ribonucleoprotein F-like K11098 SNRPF; small nuclear ribonucleoprotein F
E 107110116 small nuclear ribonucleoprotein F-like K11098 SNRPF; small nuclear ribonucleoprotein F
E 107114702 SNRPF; small nuclear ribonucleoprotein polypeptide F K11098 SNRPF; small nuclear ribonucleoprotein F
E 107118772 SNRPG; small nuclear ribonucleoprotein polypeptide G K11099 SNRPG; small nuclear ribonucleoprotein G
E 107110162 LSM10; LSM10, U7 small nuclear RNA associated K25591 LSM10; U7 snRNA-associated Sm-like protein LSm10
E 107115691 LSM11; LSM11, U7 small nuclear RNA associated K25592 LSM11; U7 snRNA-associated Sm-like protein LSm11
E 107123849 CPSF2; cleavage and polyadenylation specific factor 2 K14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2
E 107111205 CPSF3; cleavage and polyadenylation specific factor 3 K14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]
E 107124534 CSTF2; cleavage stimulation factor subunit 2 K14407 CSTF2; cleavage stimulation factor subunit 2
E 107109791 SYMPK; symplekin K06100 SYMPK; symplekin
E 107112916 SLBP; stem-loop binding protein K18710 SLBP; histone RNA hairpin-binding protein
E 107114622 CASP8AP2; caspase 8 associated protein 2 K25593 CASP8AP2; CASP8-associated protein 2
D DRB sensitivity inducing factor (DSIF) complex
E 107112501 SUPT4H1; SPT4 homolog, DSIF elongation factor subunit K15171 SUPT4H1; transcription elongation factor SPT4
E 107116790 SUPT5H; SPT5 homolog, DSIF elongation factor subunit K15172 SUPT5H; transcription elongation factor SPT5
D N6-methyltransferase complex
E 107118160 METTL3; methyltransferase like 3 K05925 METTL3; mRNA m6A methyltransferase catalytic subunit [EC:2.1.1.348]
E 107105870 METTL14; methyltransferase like 14 K23960 METTL14; mRNA m6A methyltransferase non-catalytic subunit
E 107112741 METTL4; methyltransferase like 4 K24174 METTL4; N(6)-adenine-specific DNA methyltransferase [EC:2.1.1.72]
E 107121598 METTL16; methyltransferase like 16 K11393 METTL16; U6 snRNA m6A methyltransferase [EC:2.1.1.346]
E 107111948 WTAP; Wilms tumor 1 associated protein K22824 WTAP; pre-mRNA-splicing regulator WTAP
E 107109276 KIAA1429 ortholog K22910 VIRMA; protein virilizer
E 107106432 RBM15; RNA binding motif protein 15 K13190 RBM15; RNA-binding protein 15
E 107121149 RBM15B; RNA binding motif protein 15B K13190 RBM15; RNA-binding protein 15
E 107110270 ZC3H13; zinc finger CCCH-type containing 13 K22909 ZC3H13; zinc finger CCCH domain-containing protein 13
E 107105978 CBLL1; Cbl proto-oncogene like 1 K15685 CBLL1; E3 ubiquitin-protein ligase Hakai [EC:2.3.2.27]
D Poly(A) addition factors
E 107118623 poly(A) polymerase alpha K14376 PAP; poly(A) polymerase [EC:2.7.7.19]
E 107122398 PAPOLG; poly(A) polymerase gamma K14376 PAP; poly(A) polymerase [EC:2.7.7.19]
E 107112649 PAPOLA; poly(A) polymerase alpha K14376 PAP; poly(A) polymerase [EC:2.7.7.19]
E 107123990 PAPD4; poly(A) RNA polymerase D4, non-canonical K14079 PAPD4; poly(A) RNA polymerase GLD2 [EC:2.7.7.19]
D Negative regulators of mRNA 3' end processing
E 107113164 RBM26; RNA binding motif protein 26 K13192 RBM26; RNA-binding protein 26
E 107119673 FTO; FTO, alpha-ketoglutarate dependent dioxygenase K19469 FTO; mRNA N6-methyladenine demethylase [EC:1.14.11.53]
E 107108831 ALKBH5; alkB homolog 5, RNA demethylase K10767 ALKBH5; mRNA N6-methyladenine demethylase [EC:1.14.11.53]
E 107124368 TARDBP; TAR DNA binding protein K23600 TARDBP; TAR DNA-binding protein 43
C Other processing factors
D 107123101 DHX40; DEAH-box helicase 40 K18711 DHX40; ATP-dependent RNA helicase DHX40 [EC:5.6.2.6]
D 107115344 DNA/RNA-binding protein KIN17-like K13102 KIN; DNA/RNA-binding protein KIN17
D 107119970 DNA/RNA-binding protein KIN17-like K13102 KIN; DNA/RNA-binding protein KIN17
D 107113551 METTL22; methyltransferase like 22 K23040 METTL22; methyltransferase-like protein 22 [EC:2.1.1.-]
D 107109435 FAM46A; family with sequence similarity 46 member A K23033 TENT5A_B; terminal nucleotidyltransferase 5A/B [EC:2.7.7.-]
D 107110825 FAM46B; family with sequence similarity 46 member B K23033 TENT5A_B; terminal nucleotidyltransferase 5A/B [EC:2.7.7.-]
D 107111859 FAM46C; family with sequence similarity 46 member C K23034 TENT5C; terminal nucleotidyltransferase 5C [EC:2.7.7.19]
D 107111934 protein FAM46D-like K23035 TENT5D; terminal nucleotidyltransferase 5D [EC:2.7.7.19]
D 107123455 ZC3H14; zinc finger CCCH-type containing 14 K23038 ZC3H14; zinc finger CCCH domain-containing protein 14
D 107124448 SRRT; serrate, RNA effector molecule K27103 SRRT; serrate RNA effector molecule
B mRNA surveillance and transport factors
C Transport factors
D EJC complex
E 107107952 RBM8A; RNA binding motif protein 8A K12876 RBM8A; RNA-binding protein 8A
E 107120568 MAGOH; mago homolog, exon junction complex core component K12877 MAGOH; protein mago nashi
E 107118132 ALYREF; Aly/REF export factor K12881 THOC4; THO complex subunit 4
E 107119902 DDX39B; DExD-box helicase 39B K12812 DDX39B; ATP-dependent RNA helicase UAP56/SUB2 [EC:5.6.2.7]
E 107114212 EIF4A3; eukaryotic translation initiation factor 4A3 K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]
E 107125912 CCDC174; coiled-coil domain containing 174 K25178 CCDC174; coiled-coil domain-containing protein 174
E 107108825 CASC3; cancer susceptibility candidate 3 K14323 CASC3; protein CASC3
E 107115356 SAP18; Sin3A associated protein 18 K14324 SAP18; histone deacetylase complex subunit SAP18
E 107123173 PNN; pinin, desmosome associated protein K13114 PNN; pinin
E 107106145 ACIN1; apoptotic chromatin condensation inducer 1 K12875 ACIN1; apoptotic chromatin condensation inducer in the nucleus
E 107124636 RNPS1; RNA binding protein with serine rich domain 1 K14325 RNPS1; RNA-binding protein with serine-rich domain 1
E 107121851 SRRM1; serine and arginine repetitive matrix 1 K13171 SRRM1; serine/arginine repetitive matrix protein 1
D TREX complex
E 107120575 THOC1; THO complex 1 K12878 THOC1; THO complex subunit 1
E 107123684 THOC2; THO complex 2 K12879 THOC2; THO complex subunit 2
E 107109489 THOC3; THO complex 3 K12880 THOC3; THO complex subunit 3
E 107118132 ALYREF; Aly/REF export factor K12881 THOC4; THO complex subunit 4
E 107105968 THO complex subunit 5 homolog K13174 THOC5; THO complex subunit 5
E 107122292 THO complex subunit 5 homolog K13174 THOC5; THO complex subunit 5
E 107117623 THOC6; THO complex 6 K13175 THOC6; THO complex subunit 6
E 107118032 THOC7; THO complex 7 K13176 THOC7; THO complex subunit 7
D TREX-2 complex
E 107110918 PCID2; PCI domain containing 2 K23801 PCID2; nuclear mRNA export protein PCID2/THP1
E 107124057 ENY2; ENY2, transcription and export complex 2 subunit K11368 ENY2; enhancer of yellow 2 transcription factor
E 107118208 CETN2; centrin 2 K10840 CETN2; centrin-2
E 107123781 CETN3; centrin 3 K16466 CETN3; centrin-3
E 107115799 germinal-center associated nuclear protein-like K24317 MCM3AP; germinal-center associated nuclear protein [EC:2.3.1.48]
D Nuclear pore complex
E 107113854 TPR; translocated promoter region, nuclear basket protein K09291 TPR; nucleoprotein TPR
E 107119899 RAE1; ribonucleic acid export 1 K14298 RAE1; mRNA export factor
E 107122225 SEC13; SEC13 homolog, nuclear pore and COPII coat complex component K14004 SEC13; protein transport protein SEC13
E 107120685 NUP37; nucleoporin 37 K14302 NUP37; nuclear pore complex protein Nup37
E 107110032 NUP85; nucleoporin 85 K14304 NUP85; nuclear pore complex protein Nup85
E 107109503 NUP43; nucleoporin 43 K14305 NUP43; nuclear pore complex protein Nup43
E 107114065 NUP50; nucleoporin 50 K14295 NUP50; nuclear pore complex protein Nup50
E 107115657 nuclear pore complex protein Nup54-like K14308 NUP54; nuclear pore complex protein Nup54
E 107123771 NUP54; nucleoporin 54 K14308 NUP54; nuclear pore complex protein Nup54
E 107108532 NUP62CL; nucleoporin 62 C-terminal like K14306 NUP62; nuclear pore complex protein Nup62
E 107107694 NUP88; nucleoporin 88 K14318 NUP88; nuclear pore complex protein Nup88
E 107118977 NUP93; nucleoporin 93 K14309 NUP93; nuclear pore complex protein Nup93
E 107124802 NUP98; nucleoporin 98 K14297 NUP98; nuclear pore complex protein Nup98-Nup96
E 107105713 NUP107; nucleoporin 107 K14301 NUP107; nuclear pore complex protein Nup107
E 107119014 NUP133; nucleoporin 133 K14300 NUP133; nuclear pore complex protein Nup133
E 107115668 NUP188; nucleoporin 188 K14311 NUP188; nuclear pore complex protein Nup188
E 107106158 NUP153; nucleoporin 153 K14296 NUP153; nuclear pore complex protein Nup153
E 107117960 NUP155; nucleoporin 155 K14312 NUP155; nuclear pore complex protein Nup155
E 107113206 NUP160; nucleoporin 160 K14303 NUP160; nuclear pore complex protein Nup160
E 107106011 NUP35; nucleoporin 35 K14313 NUP35; nuclear pore complex protein Nup53
E 107118921 NUP205; nucleoporin 205 K14310 NUP205; nuclear pore complex protein Nup205
E 107125460 NUP210; nucleoporin 210 K14314 NUP210; nuclear pore complex protein Nup210
E 107110878 NUP210L; nucleoporin 210 like K14314 NUP210; nuclear pore complex protein Nup210
E 107121346 NUP214; nucleoporin 214 K14317 NUP214; nuclear pore complex protein Nup214
E 107112415 POM121; POM121 transmembrane nucleoporin K14316 POM121; nuclear pore complex protein Nup121
E 107117274 NUP58; nucleoporin 58 K14307 NUPL1; nucleoporin p58/p45
E 107106898 NUPL2; nucleoporin like 2 K14321 NUPL2; nucleoporin-like protein 2
E 107124285 NDC1; NDC1 transmembrane nucleoporin K14315 NDC1; nucleoporin NDC1
E 107113094 SEH1L; SEH1 like nucleoporin K14299 SEH1; nucleoporin SEH1
E 107117568 RANBP2; RAN binding protein 2 K12172 RANBP2; E3 SUMO-protein ligase RanBP2 [EC:2.3.2.-]
E 107123581 SENP2; SUMO1/sentrin/SMT3 specific peptidase 2 K03345 SENP2; sentrin-specific protease 2 (axin associating molecule) [EC:3.4.22.68]
E 107119669 AAAS; aladin WD repeat nucleoporin K14320 AAAS; aladin
E 107123781 CETN3; centrin 3 K16466 CETN3; centrin-3
E 107123246 GLE1; GLE1, RNA export mediator K18723 GLE1; nucleoporin GLE1
E 107115206 NXF1; nuclear RNA export factor 1 K14284 NXF; nuclear RNA export factor
E 107114013 NXT2; nuclear transport factor 2 like export factor 2 K14285 NXT1_2; NTF2-related export protein 1/2
D Ran-mediated transport factors
E 107116017 RAN; RAN, member RAS oncogene family K07936 RAN; GTP-binding nuclear protein Ran
E 107111366 ANP32A; acidic nuclear phosphoprotein 32 family member A K18646 ANP32A_C_D; acidic leucine-rich nuclear phosphoprotein 32 family member A/C/D
E 107112176 acidic leucine-rich nuclear phosphoprotein 32 family member B-like K18647 ANP32B; acidic leucine-rich nuclear phosphoprotein 32 family member B
E 107118354 ANP32B; acidic nuclear phosphoprotein 32 family member B K18647 ANP32B; acidic leucine-rich nuclear phosphoprotein 32 family member B
E 107119813 uncharacterized LOC107119813 K05475 TNFSF13; tumor necrosis factor ligand superfamily member 13
E 107120009 ELAVL1; ELAV like RNA binding protein 1 K13088 ELAVL1; ELAV-like protein 1
E 107106170 ELAVL4; ELAV like RNA binding protein 4 K13208 ELAVL2_3_4; ELAV like protein 2/3/4
E 107124308 ELAVL2; ELAV like RNA binding protein 2 K13208 ELAVL2_3_4; ELAV like protein 2/3/4
E 107111281 ELAVL3; ELAV like RNA binding protein 3 K13208 ELAVL2_3_4; ELAV like protein 2/3/4
E 107111537 FAF2; Fas associated factor family member 2 K18726 FAF2; FAS-associated factor 2
E 107106633 VCP; valosin containing protein K13525 VCP; transitional endoplasmic reticulum ATPase
E 107113821 transitional endoplasmic reticulum ATPase-like K13525 VCP; transitional endoplasmic reticulum ATPase
E 107122629 VCPKMT; valosin containing protein lysine methyltransferase K21806 VCPKMT; protein N-lysine methyltransferase METTL21D [EC:2.1.1.-]
E 107114415 TNPO2; transportin 2 K18727 TNPO2; transportin-2
E 107108413 XPO1; exportin 1 K14290 XPO1; exportin-1
E 107120331 XPO7; exportin 7 K18460 XPO7; exportin-7
E 107112548 RANBP17; RAN binding protein 17 K24115 RANBP17; Ran-binding protein 17
E 107117108 RANGAP1; Ran GTPase activating protein 1 K14319 RANGAP1; Ran GTPase-activating protein 1
E 107107729 TAF15; TATA-box binding protein associated factor 15 K14651 TAF15; transcription initiation factor TFIID subunit 15
D eIF4F and regulatory proteins
E 107107523 EIF4E2; eukaryotic translation initiation factor 4E family member 2 K03259 EIF4E; translation initiation factor 4E
E 107111534 EIF4E1B; eukaryotic translation initiation factor 4E family member 1B K03259 EIF4E; translation initiation factor 4E
E 107114476 EIF4E; eukaryotic translation initiation factor 4E K03259 EIF4E; translation initiation factor 4E
E 107122366 EIF4A2; eukaryotic translation initiation factor 4A2 K03257 EIF4A; translation initiation factor 4A
E 107118081 EIF4A1; eukaryotic translation initiation factor 4A1 K03257 EIF4A; translation initiation factor 4A
E 107106769 EIF4G2; eukaryotic translation initiation factor 4 gamma 2 K03260 EIF4G; translation initiation factor 4G
E 107123695 EIF4G1; eukaryotic translation initiation factor 4 gamma 1 K03260 EIF4G; translation initiation factor 4G
E 107111628 EIF4G3; eukaryotic translation initiation factor 4 gamma 3 K03260 EIF4G; translation initiation factor 4G
E 107119807 EIF4B; eukaryotic translation initiation factor 4B K03258 EIF4B; translation initiation factor 4B
E 107124937 EIF4H; eukaryotic translation initiation factor 4H K24086 EIF4H; translation initiation factor 4H
E 107108168 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1 K07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
E 107115107 EIF4ENIF1; eukaryotic translation initiation factor 4E nuclear import factor 1 K18728 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter
E 107124209 ANGEL2; angel homolog 2 K18729 ANGEL; protein angel
E 107116461 ANGEL1; angel homolog 1 K18729 ANGEL; protein angel
E 107125841 FXR1; FMR1 autosomal homolog 1 K15516 FMR; fragile X mental retardation protein
E 107121461 FMR1; fragile X mental retardation 1 K15516 FMR; fragile X mental retardation protein
E 107118106 FXR2; FMR1 autosomal homolog 2 K15516 FMR; fragile X mental retardation protein
E 107124835 cytoplasmic FMR1-interacting protein 2 K05749 CYFIP; cytoplasmic FMR1 interacting protein
E 107110223 cytoplasmic FMR1-interacting protein 1 K05749 CYFIP; cytoplasmic FMR1 interacting protein
E 107115384 GEMIN5; gem nuclear organelle associated protein 5 K13133 GEMIN5; gem associated protein 5
E 107117798 TACC3; transforming acidic coiled-coil containing protein 3 K14283 TACC3; transforming acidic coiled-coil-containing protein 3
E 107110245 cytoplasmic polyadenylation element-binding protein 3-like K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 107116757 CPEB1; cytoplasmic polyadenylation element binding protein 1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 107121563 cytoplasmic polyadenylation element-binding protein 2-like K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 107109003 CPEB4; cytoplasmic polyadenylation element binding protein 4 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 107116544 DDX3X; DEAD-box helicase 3, X-linked K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]
E 107123596 GIGYF2; GRB10 interacting GYF protein 2 K18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein
E 107124420 GIGYF1; GRB10 interacting GYF protein 1 K18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein
E 107115972 PABPC4; poly(A) binding protein cytoplasmic 4 K13126 PABPC; polyadenylate-binding protein
E 107124745 PABPC1; poly(A) binding protein cytoplasmic 1 K13126 PABPC; polyadenylate-binding protein
E 107116153 PABPC1L; poly(A) binding protein cytoplasmic 1 like K13126 PABPC; polyadenylate-binding protein
E 107121544 PAIP1; poly(A) binding protein interacting protein 1 K14322 PAIP1; polyadenylate-binding protein-interacting protein 1
E 107110259 PAIP2; poly(A) binding protein interacting protein 2 K27470 PAIP2; polyadenylate-binding protein-interacting protein 2
E 107112673 PAIP2B; poly(A) binding protein interacting protein 2B K27470 PAIP2; polyadenylate-binding protein-interacting protein 2
E 107105479 SKIV2L; Ski2 like RNA helicase K12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6]
E 107112902 DEAF1; DEAF1, transcription factor K23041 DEAF1; deformed epidermal autoregulatory factor 1
E 107123727 MCTS1; MCTS1, re-initiation and release factor K07575 MCTS; malignant T-cell-amplified sequence
E 107115905 DENR; density regulated re-initiation and release factor K24272 DENR; density-regulated protein
D APOBEC1-ACF complex
E 107108745 A1CF; APOBEC1 complementation factor K24978 A1CF; APOBEC1 complementation factor
D Other transport factors
E 107105858 PYM1; PYM homolog 1, exon junction complex associated factor K14294 WIBG; partner of Y14 and mago
E 107119831 HNRNPA3; heterogeneous nuclear ribonucleoprotein A3 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 107122621 HNRNPA1; heterogeneous nuclear ribonucleoprotein A1 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 107126099 MSI1; musashi RNA binding protein 1 K14411 MSI; RNA-binding protein Musashi
E 107119453 MSI2; musashi RNA binding protein 2 K14411 MSI; RNA-binding protein Musashi
E 107115755 DAZAP1; DAZ associated protein 1 K14411 MSI; RNA-binding protein Musashi
E 107111681 HBS1L; HBS1 like translational GTPase K14416 HBS1; elongation factor 1 alpha-like protein
E 107117046 PELO; pelota homolog (Drosophila) K06965 PELO; protein pelota
E 107106132 polyadenylate-binding protein 2-like K14396 PABPN1; polyadenylate-binding protein 2
E 107122783 embryonic polyadenylate-binding protein 2-like K14396 PABPN1; polyadenylate-binding protein 2
E 107124526 ATP-dependent RNA helicase DDX19B K18655 DDX19; ATP-dependent RNA helicase DDX19/DBP5 [EC:5.6.2.7]
E 107125921 DDX25; DEAD-box helicase 25 K18656 DDX25; ATP-dependent RNA helicase DDX25 [EC:5.6.2.7]
E 107111602 XAB2; XPA binding protein 2 K12867 SYF1; pre-mRNA-splicing factor SYF1
E 107105865 SARNP; SAP domain containing ribonucleoprotein K18732 SARNP; SAP domain-containing ribonucleoprotein
E 107108682 RCC1; regulator of chromosome condensation 1 K11493 RCC1; regulator of chromosome condensation
E 107125407 la-related protein 6-like K18733 LARP6; la-related protein 6
E 107117865 la-related protein 6-like K18733 LARP6; la-related protein 6
E 107119729 PURA; purine rich element binding protein A K21772 PURA; transcriptional activator protein Pur-alpha
E 107107837 PURB; purine rich element binding protein B K21799 PURB; transcriptional activator protein Pur-beta
E 107118374 POLDIP3; DNA polymerase delta interacting protein 3 K22414 POLDIP3; polymerase delta-interacting protein 3
E 107107094 ZC3H11A; zinc finger CCCH-type containing 11A K22415 ZC3H11; zinc finger CCCH domain-containing protein 11
E 107115635 LENG8; leukocyte receptor cluster member 8 K23802 LENG8; SAC3 family protein LENG8/THP3
E 107111434 PATL2; PAT1 homolog 2 K24823 PATL2; protein PAT1 homolog 2
C Surveillance factors
D Surveillance complex
E 107106743 ETF1; eukaryotic translation termination factor 1 K03265 ETF1; peptide chain release factor subunit 1
E 107114070 GSPT1; G1 to S phase transition 1 K03267 ERF3; peptide chain release factor subunit 3
E 107105636 UPF1; UPF1, RNA helicase and ATPase K14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3]
E 107111124 UPF2; UPF2 regulator of nonsense transcripts homolog (yeast) K14327 UPF2; regulator of nonsense transcripts 2
E 107125851 UPF3A; UPF3 regulator of nonsense transcripts homolog A (yeast) K14328 UPF3; regulator of nonsense transcripts 3
E 107123725 UPF3B; UPF3 regulator of nonsense transcripts homolog B (yeast) K14328 UPF3; regulator of nonsense transcripts 3
D Protein phosphatase 2A
E 107125982 PPP2CA; protein phosphatase 2 catalytic subunit alpha K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
E 107110575 serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
E 107124393 PPP2R1A; protein phosphatase 2 scaffold subunit Aalpha K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
E 107126265 PPP2R2A; protein phosphatase 2 regulatory subunit Balpha K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
E 107108836 PPP2R2D; protein phosphatase 2 regulatory subunit Bdelta K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
E 107112470 PPP2R2B; protein phosphatase 2 regulatory subunit Bbeta K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
E 107121378 PPP2R2C; protein phosphatase 2 regulatory subunit Bgamma K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
E 107114806 PPP2R3C; protein phosphatase 2 regulatory subunit B''gamma K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
E 107110228 PPP2R3B; protein phosphatase 2 regulatory subunit B''beta K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
E 107123594 PPP2R3A; protein phosphatase 2 regulatory subunit B''alpha K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
E 107116652 PPP2R5C; protein phosphatase 2 regulatory subunit B'gamma K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
E 107123087 PPP2R5D; protein phosphatase 2 regulatory subunit B'delta K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
E 107124204 PPP2R5A; protein phosphatase 2 regulatory subunit B'alpha K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
E 107110121 PPP2R5B; protein phosphatase 2 regulatory subunit B'beta K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
E 107124785 PPP2R5E; protein phosphatase 2 regulatory subunit B'epsilon K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
D Other surveillance factors
E 107118525 SMG1; SMG1, nonsense mediated mRNA decay associated PI3K related kinase K08873 SMG1; serine/threonine-protein kinase SMG1 [EC:2.7.11.1]
E 107110079 SMG5; SMG5, nonsense mediated mRNA decay factor K11125 SMG5; protein SMG5
E 107119443 SMG6; SMG6, nonsense mediated mRNA decay factor K11124 SMG6; protein SMG6 [EC:3.1.-.-]
E 107117515 SMG7; SMG7, nonsense mediated mRNA decay factor K14409 SMG7; protein SMG7
E 107121276 SMG8; SMG8, nonsense mediated mRNA decay factor K18734 SMG8; protein SMG8
E 107107556 SMG9; SMG9, nonsense mediated mRNA decay factor K18735 SMG9; protein SMG9
E 107123596 GIGYF2; GRB10 interacting GYF protein 2 K18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein
E 107124420 GIGYF1; GRB10 interacting GYF protein 1 K18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein
E 107108628 SECISBP2; SECIS binding protein 2 K19539 SECISBP2; selenocysteine insertion sequence-binding protein 2
E 107124466 SECISBP2L; SECIS binding protein 2 like K19539 SECISBP2; selenocysteine insertion sequence-binding protein 2
E 107106909 DHX34; DExH-box helicase 34 K20101 DHX34; ATP-dependent RNA helicase DHX34 [EC:5.6.2.6]
E 107117168 GTPBP1; GTP binding protein 1 K24887 GTPBP1; GTP-binding protein 1
C Factors involved in mRNA localization
D Cargo complex
E 107122856 PUM3; pumilio RNA binding family member 3 K14844 PUF6; pumilio homology domain family member 6
E 107116800 MYO5C; myosin VC K10357 MYO5; myosin V
E 107116697 MYO5A; myosin VA K10357 MYO5; myosin V
E 107114963 unconventional myosin-Vb-like K10357 MYO5; myosin V
E 107111870 BICD1; BICD cargo adaptor 1 K18739 BICD; protein bicaudal D
E 107105523 BICD2; BICD cargo adaptor 2 K18739 BICD; protein bicaudal D
E 107114020 protein bicaudal D homolog 2-like K18739 BICD; protein bicaudal D
E 107126010 EXD1; exonuclease 3'-5' domain containing 1 K18740 EXD1; exonuclease 3'-5' domain-containing protein 1
D Factors that have mRNA localization signals
E 107106287 actin, cytoplasmic 1-like K05692 ACTB_G1; actin beta/gamma 1
E 107108307 ACTG1; actin gamma 1 K05692 ACTB_G1; actin beta/gamma 1
E 107117852 actin, cytoplasmic type 5 K05692 ACTB_G1; actin beta/gamma 1
E 107111804 MBP; myelin basic protein K17269 MBP; myelin basic protein
E 107120972 VIM; vimentin K07606 VIM; vimentin
E 107116306 metallothionein-like K14739 MT1_2; metallothionein 1/2
E 107118987 metallothionein K14739 MT1_2; metallothionein 1/2
E 107122472 MYC; v-myc avian myelocytomatosis viral oncogene homolog K04377 MYC; Myc proto-oncogene protein
E 107105634 GDF1; growth differentiation factor 1 K05495 GDF1; growth differentiation factor 1
E 107108513 T-box-containing protein TBX6L-like K10180 TBX6; T-box protein 6
E 107117443 TBX6; T-box 6 K10180 TBX6; T-box protein 6
E 107106722 NANOS1; nanos C2HC-type zinc finger 1 K18741 NANOS1; protein nanos 1
D Trans-acting binding proteins
E 107110711 FUBP3; far upstream element binding protein 3 K13210 FUBP; far upstream element-binding protein
E 107113033 FUBP1; far upstream element binding protein 1 K13210 FUBP; far upstream element-binding protein
E 107120160 far upstream element-binding protein 2-like K13210 FUBP; far upstream element-binding protein
E 107123190 EEF1A1; eukaryotic translation elongation factor 1 alpha 1 K03231 EEF1A; elongation factor 1-alpha
E 107109946 elongation factor 1-alpha 2 K03231 EEF1A; elongation factor 1-alpha
E 107120830 EEF1G; eukaryotic translation elongation factor 1 gamma K03233 EEF1G; elongation factor 1-gamma
E 107116636 HNRNPA2B1; heterogeneous nuclear ribonucleoprotein A2/B1 K13158 HNRNPA2B1; heterogeneous nuclear ribonucleoprotein A2/B1
E 107117094 HAX1; HCLS1 associated protein X-1 K16220 HAX1; HCLS1-associated protein X-1
E 107116005 AGFG1; ArfGAP with FG repeats 1 K15044 AGFG1; Arf-GAP domain and FG repeats-containing protein 1
E 107114648 STAU2; staufen double-stranded RNA binding protein 2 K17597 STAU; double-stranded RNA-binding protein Staufen
E 107110182 STAU1; staufen double-stranded RNA binding protein 1 K17597 STAU; double-stranded RNA-binding protein Staufen
E 107116850 IGF2BP3; insulin like growth factor 2 mRNA binding protein 3 K13197 IGF2BP3; insulin-like growth factor 2 mRNA-binding protein 3
E 107116329 PTBP1; polypyrimidine tract binding protein 1 K13218 PTBP1; polypyrimidine tract-binding protein 1
E 107110245 cytoplasmic polyadenylation element-binding protein 3-like K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 107116757 CPEB1; cytoplasmic polyadenylation element binding protein 1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 107121563 cytoplasmic polyadenylation element-binding protein 2-like K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 107109003 CPEB4; cytoplasmic polyadenylation element binding protein 4 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
D Other mRNA localization factors
E 107125841 FXR1; FMR1 autosomal homolog 1 K15516 FMR; fragile X mental retardation protein
E 107121461 FMR1; fragile X mental retardation 1 K15516 FMR; fragile X mental retardation protein
E 107118106 FXR2; FMR1 autosomal homolog 2 K15516 FMR; fragile X mental retardation protein
E 107124835 cytoplasmic FMR1-interacting protein 2 K05749 CYFIP; cytoplasmic FMR1 interacting protein
E 107110223 cytoplasmic FMR1-interacting protein 1 K05749 CYFIP; cytoplasmic FMR1 interacting protein
E 107119678 PCBP2; poly(rC) binding protein 2 K13162 PCBP2; poly(rC)-binding protein 2
E 107118447 poly(rC)-binding protein 3-like K21444 PCBP3_4; poly(rC)-binding protein 3/4
E 107120735 PCBP3; poly(rC) binding protein 3 K21444 PCBP3_4; poly(rC)-binding protein 3/4
E 107115928 PCBP4; poly(rC) binding protein 4 K21444 PCBP3_4; poly(rC)-binding protein 3/4
E 107110141 CAPRIN1; cell cycle associated protein 1 K18743 CAPRIN1; caprin-1
E 107110611 CAPRIN2; caprin family member 2 K18744 CAPRIN2; caprin-2
E 107121277 YBX1; Y-box binding protein 1 K09276 YBX1; Y-box-binding protein 1
C mRNA cycle factors
D Common to processing body (P body) and stress granule
E 107112361 XRN1; 5'-3' exoribonuclease 1 K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]
E 107126113 protein argonaute-1 K11593 ELF2C; eukaryotic translation initiation factor 2C
E 107126114 protein argonaute-3 K11593 ELF2C; eukaryotic translation initiation factor 2C
E 107126115 AGO4; argonaute 4, RISC catalytic component K11593 ELF2C; eukaryotic translation initiation factor 2C
E 107124772 protein argonaute-2-like K11593 ELF2C; eukaryotic translation initiation factor 2C
E 107107523 EIF4E2; eukaryotic translation initiation factor 4E family member 2 K03259 EIF4E; translation initiation factor 4E
E 107111534 EIF4E1B; eukaryotic translation initiation factor 4E family member 1B K03259 EIF4E; translation initiation factor 4E
E 107114476 EIF4E; eukaryotic translation initiation factor 4E K03259 EIF4E; translation initiation factor 4E
E 107105636 UPF1; UPF1, RNA helicase and ATPase K14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3]
E 107116544 DDX3X; DEAD-box helicase 3, X-linked K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]
E 107124566 DDX6; DEAD-box helicase 6 K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7]
E 107118606 MEX3B; mex-3 RNA binding family member B K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
E 107122005 MEX3C; mex-3 RNA binding family member C K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
E 107118055 MEX3A; mex-3 RNA binding family member A K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
E 107109955 RNA-binding protein MEX3D-like K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
E 107108218 FASTK; Fas activated serine/threonine kinase K08290 FASTK; Fas-activated serine/threonine kinase [EC:2.7.11.8]
E 107106049 LSM14B; LSM family member 14B K18749 LSM14; protein LSM14
E 107110328 LSM14A; LSM14A, mRNA processing body assembly factor K18749 LSM14; protein LSM14
E 107119678 PCBP2; poly(rC) binding protein 2 K13162 PCBP2; poly(rC)-binding protein 2
E 107121277 YBX1; Y-box binding protein 1 K09276 YBX1; Y-box-binding protein 1
E 107111294 LIMD1; LIM domains containing 1 K16682 AJUBA; LIM domain-containing protein
E 107110319 WTIP; Wilms tumor 1 interacting protein K16682 AJUBA; LIM domain-containing protein
E 107115394 DNA dC->dU-editing enzyme APOBEC-3G-like K18750 APOBEC3; C->U-editing enzyme APOBEC3 [EC:3.5.4.-]
E 107108152 putative helicase MOV-10 K18422 MOV10; helicase MOV-10 [EC:5.6.2.5]
E 107110302 MOV10; Mov10 RISC complex RNA helicase K18422 MOV10; helicase MOV-10 [EC:5.6.2.5]
E 107124119 PNRC2; proline rich nuclear receptor coactivator 2 K18751 PNRC2; proline-rich nuclear receptor coactivator 2
E 107112464 TNPO1; transportin 1 K18752 TNPO1; transportin-1
E 107118525 SMG1; SMG1, nonsense mediated mRNA decay associated PI3K related kinase K08873 SMG1; serine/threonine-protein kinase SMG1 [EC:2.7.11.1]
E 107110079 SMG5; SMG5, nonsense mediated mRNA decay factor K11125 SMG5; protein SMG5
E 107119443 SMG6; SMG6, nonsense mediated mRNA decay factor K11124 SMG6; protein SMG6 [EC:3.1.-.-]
E 107117515 SMG7; SMG7, nonsense mediated mRNA decay factor K14409 SMG7; protein SMG7
E 107116792 tristetraprolin-like K15308 TTP; tristetraprolin
E 107109511 ZFP36L2; ZFP36 ring finger protein like 2 K18753 ZFP36L; butyrate response factor
E 107116784 zinc finger protein 36, C3H1 type-like 1 K18753 ZFP36L; butyrate response factor
E 107112197 ZFP36L1; ZFP36 ring finger protein like 1 K18753 ZFP36L; butyrate response factor
E 107124357 LIN28B; lin-28 homolog B K18754 LIN28; protein lin-28
E 107110422 LIN28A; lin-28 homolog A K18754 LIN28; protein lin-28
E 107118340 HTT; huntingtin K04533 HD; huntingtin
E 107110610 IPO8; importin 8 K18755 IPO8; importin-8
E 107117755 BICC1; BicC family RNA binding protein 1 K18756 BICC1; protein bicaudal C
E 107119831 HNRNPA3; heterogeneous nuclear ribonucleoprotein A3 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 107122621 HNRNPA1; heterogeneous nuclear ribonucleoprotein A1 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 107117304 PRKACB; protein kinase cAMP-activated catalytic subunit beta K04345 PKA; protein kinase A [EC:2.7.11.11]
E 107117579 cAMP-dependent protein kinase catalytic subunit alpha K04345 PKA; protein kinase A [EC:2.7.11.11]
E 107109744 LARP1B; La ribonucleoprotein domain family member 1B K18757 LARP1; la-related protein 1
E 107115377 LARP1; La ribonucleoprotein domain family member 1 K18757 LARP1; la-related protein 1
E 107112147 ATXN2; ataxin 2 K23625 ATXN2_2L; ataxin 2/2L
E 107122682 ATXN2L; ataxin 2 like K23625 ATXN2_2L; ataxin 2/2L
D P-body specific factors
E 107116680 DCP2; decapping mRNA 2 K12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62]
E 107125423 DCP1A; decapping mRNA 1A K12610 DCP1A; mRNA-decapping enzyme 1A [EC:3.-.-.-]
E 107120234 DCP1B; decapping mRNA 1B K12611 DCP1B; mRNA-decapping enzyme 1B [EC:3.-.-.-]
E 107122031 LSM1; LSM1 homolog, mRNA degradation associated K12620 LSM1; U6 snRNA-associated Sm-like protein LSm1
E 107108245 LSM2; LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated K12621 LSM2; U6 snRNA-associated Sm-like protein LSm2
E 107125915 LSM3; LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3
E 107105738 LSM5; LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated K12624 LSM5; U6 snRNA-associated Sm-like protein LSm5
E 107120274 LSM6; LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6
E 107118491 LSM7; LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated K12626 LSM7; U6 snRNA-associated Sm-like protein LSm7
E 107113914 LSM8; LSM8 homolog, U6 small nuclear RNA associated K12627 LSM8; U6 snRNA-associated Sm-like protein LSm8
E 107114935 KLC3; kinesin light chain 3 K10407 KLC; kinesin light chain
E 107123083 KLC4; kinesin light chain 4 K10407 KLC; kinesin light chain
E 107117508 KLC2; kinesin light chain 2 K10407 KLC; kinesin light chain
E 107115988 KLC1; kinesin light chain 1 K10407 KLC; kinesin light chain
E 107116800 MYO5C; myosin VC K10357 MYO5; myosin V
E 107116697 MYO5A; myosin VA K10357 MYO5; myosin V
E 107114963 unconventional myosin-Vb-like K10357 MYO5; myosin V
E 107110544 tubulin alpha-3 chain K07374 TUBA; tubulin alpha
E 107126161 tubulin alpha-3 chain K07374 TUBA; tubulin alpha
E 107126162 tubulin alpha-3 chain-like K07374 TUBA; tubulin alpha
E 107107863 tubulin alpha-8 chain-like K07374 TUBA; tubulin alpha
E 107108029 tubulin alpha-8 chain K07374 TUBA; tubulin alpha
E 107108031 tubulin alpha-8 chain-like K07374 TUBA; tubulin alpha
E 107105862 TUBA1B; tubulin alpha 1b K07374 TUBA; tubulin alpha
E 107105863 TUBA1A; tubulin alpha 1a K07374 TUBA; tubulin alpha
E 107105839 tubulin alpha-1C chain-like K07374 TUBA; tubulin alpha
E 107123634 TUBA4A; tubulin alpha 4a K07374 TUBA; tubulin alpha
E 107123636 tubulin alpha-1D chain K07374 TUBA; tubulin alpha
E 107123995 tubulin alpha-8 chain K07374 TUBA; tubulin alpha
E 107110245 cytoplasmic polyadenylation element-binding protein 3-like K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 107116757 CPEB1; cytoplasmic polyadenylation element binding protein 1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 107121563 cytoplasmic polyadenylation element-binding protein 2-like K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 107109003 CPEB4; cytoplasmic polyadenylation element binding protein 4 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 107115384 GEMIN5; gem nuclear organelle associated protein 5 K13133 GEMIN5; gem associated protein 5
E 107117798 TACC3; transforming acidic coiled-coil containing protein 3 K14283 TACC3; transforming acidic coiled-coil-containing protein 3
E 107106273 TNRC6A; trinucleotide repeat containing 6A K18412 TNRC6; trinucleotide repeat-containing gene 6 protein
E 107117171 TNRC6B; trinucleotide repeat containing 6B K18412 TNRC6; trinucleotide repeat-containing gene 6 protein
E 107123758 TNRC6C; trinucleotide repeat containing 6C K18412 TNRC6; trinucleotide repeat-containing gene 6 protein
E 107125682 CCR4-NOT transcription complex subunit 1-like K12604 CNOT1; CCR4-NOT transcription complex subunit 1
E 107118551 CCR4-NOT transcription complex subunit 1 K12604 CNOT1; CCR4-NOT transcription complex subunit 1
E 107105708 CNOT2; CCR4-NOT transcription complex subunit 2 K12605 CNOT2; CCR4-NOT transcription complex subunit 2
E 107113135 CNOT3; CCR4-NOT transcription complex subunit 3 K12580 CNOT3; CCR4-NOT transcription complex subunit 3
E 107118904 CNOT4; CCR4-NOT transcription complex subunit 4 K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]
E 107118872 CNOT6L; CCR4-NOT transcription complex subunit 6 like K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
E 107123713 CNOT6; CCR4-NOT transcription complex subunit 6 K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
E 107115379 CNOT8; CCR4-NOT transcription complex subunit 8 K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E 107116758 CNOT7; CCR4-NOT transcription complex subunit 7 K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E 107110329 KIAA0355 ortholog K26671 GARRE1; granule associated Rac and RHOG effector protein 1
E 107113454 DIS3L2; DIS3 like 3'-5' exoribonuclease 2 K18758 DIS3L2; DIS3-like exonuclease 2 [EC:3.1.13.-]
E 107126202 PAN2; PAN2 poly(A) specific ribonuclease subunit K12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4]
E 107105449 PAN3; PAN3 poly(A) specific ribonuclease subunit K12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3
E 107118593 BTG1; BTG anti-proliferation factor 1 K14443 TOB; protein Tob/BTG
E 107124389 protein BTG3-like K14443 TOB; protein Tob/BTG
E 107117158 TOB2; transducer of ERBB2, 2 K14443 TOB; protein Tob/BTG
E 107122116 BTG4; BTG anti-proliferation factor 4 K14443 TOB; protein Tob/BTG
E 107121893 protein BTG2-like K14443 TOB; protein Tob/BTG
E 107115528 protein BTG1-like K14443 TOB; protein Tob/BTG
E 107110024 TOB1; transducer of ERBB2, 1 K14443 TOB; protein Tob/BTG
E 107115107 EIF4ENIF1; eukaryotic translation initiation factor 4E nuclear import factor 1 K18728 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter
E 107117563 PATL1; PAT1 homolog 1, processing body mRNA decay factor K12617 PATL1; DNA topoisomerase 2-associated protein PAT1
E 107114915 EDC3; enhancer of mRNA decapping 3 K12615 EDC3; enhancer of mRNA-decapping protein 3
E 107112767 EDC4; enhancer of mRNA decapping 4 K12616 EDC4; enhancer of mRNA-decapping protein 4
E 107118526 nanos homolog 2-like K18760 NANOS2; protein nanos 2
E 107125016 nanos homolog 2-like K18760 NANOS2; protein nanos 2
E 107111124 UPF2; UPF2 regulator of nonsense transcripts homolog (yeast) K14327 UPF2; regulator of nonsense transcripts 2
E 107125851 UPF3A; UPF3 regulator of nonsense transcripts homolog A (yeast) K14328 UPF3; regulator of nonsense transcripts 3
E 107123725 UPF3B; UPF3 regulator of nonsense transcripts homolog B (yeast) K14328 UPF3; regulator of nonsense transcripts 3
E 107116499 TRIM71; tripartite motif containing 71 K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
E 107111243 POLR2G; RNA polymerase II subunit G K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7
E 107111831 ZAR1; zygote arrest 1 K18762 ZAR1; zygote arrest protein 1
E 107121298 ZAR1L; zygote arrest 1-like K18762 ZAR1; zygote arrest protein 1
E 107110870 YTHDF3; YTH N6-methyladenosine RNA binding protein 3 K20102 YTHDF; YTH domain-containing family protein
E 107115439 YTHDF1; YTH N6-methyladenosine RNA binding protein 1 K20102 YTHDF; YTH domain-containing family protein
E 107121834 YTHDF2; YTH N6-methyladenosine RNA binding protein 2 K20102 YTHDF; YTH domain-containing family protein
D Stress granule specific factors
E 107106731 TIAL1; TIA1 cytotoxic granule associated RNA binding protein like 1 K13201 TIA1; nucleolysin TIA-1/TIAR
E 107118775 TIA1; TIA1 cytotoxic granule associated RNA binding protein K13201 TIA1; nucleolysin TIA-1/TIAR
E 107115972 PABPC4; poly(A) binding protein cytoplasmic 4 K13126 PABPC; polyadenylate-binding protein
E 107124745 PABPC1; poly(A) binding protein cytoplasmic 1 K13126 PABPC; polyadenylate-binding protein
E 107116153 PABPC1L; poly(A) binding protein cytoplasmic 1 like K13126 PABPC; polyadenylate-binding protein
E 107114648 STAU2; staufen double-stranded RNA binding protein 2 K17597 STAU; double-stranded RNA-binding protein Staufen
E 107110182 STAU1; staufen double-stranded RNA binding protein 1 K17597 STAU; double-stranded RNA-binding protein Staufen
E 107125841 FXR1; FMR1 autosomal homolog 1 K15516 FMR; fragile X mental retardation protein
E 107121461 FMR1; fragile X mental retardation 1 K15516 FMR; fragile X mental retardation protein
E 107118106 FXR2; FMR1 autosomal homolog 2 K15516 FMR; fragile X mental retardation protein
E 107120009 ELAVL1; ELAV like RNA binding protein 1 K13088 ELAVL1; ELAV-like protein 1
E 107113899 G3BP1; G3BP stress granule assembly factor 1 K17265 G3BP1; Ras GTPase-activating protein-binding protein 1 [EC:5.6.2.5 5.6.2.3]
E 107105567 G3BP2; G3BP stress granule assembly factor 2 K24983 G3BP2; Ras GTPase-activating protein-binding protein 2
E 107121514 EIF2A; eukaryotic translation initiation factor 2A K15026 EIF2A; translation initiation factor 2A
E 107119564 EIF3B; eukaryotic translation initiation factor 3 subunit B K03253 EIF3B; translation initiation factor 3 subunit B
E 107122366 EIF4A2; eukaryotic translation initiation factor 4A2 K03257 EIF4A; translation initiation factor 4A
E 107118081 EIF4A1; eukaryotic translation initiation factor 4A1 K03257 EIF4A; translation initiation factor 4A
E 107114212 EIF4A3; eukaryotic translation initiation factor 4A3 K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]
E 107119807 EIF4B; eukaryotic translation initiation factor 4B K03258 EIF4B; translation initiation factor 4B
E 107106769 EIF4G2; eukaryotic translation initiation factor 4 gamma 2 K03260 EIF4G; translation initiation factor 4G
E 107123695 EIF4G1; eukaryotic translation initiation factor 4 gamma 1 K03260 EIF4G; translation initiation factor 4G
E 107111628 EIF4G3; eukaryotic translation initiation factor 4 gamma 3 K03260 EIF4G; translation initiation factor 4G
E 107108893 RPS6KA1; ribosomal protein S6 kinase A1 K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
E 107107196 ribosomal protein S6 kinase alpha-6 K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
E 107110539 RPS6KA3; ribosomal protein S6 kinase A3 K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
E 107124531 RPS6KA2; ribosomal protein S6 kinase A2 K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
E 107120827 RACK1; receptor for activated C kinase 1 K14753 RACK1; guanine nucleotide-binding protein subunit beta-2-like 1 protein
E 107115164 TRAF2; TNF receptor associated factor 2 K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
E 107118266 TNF receptor-associated factor 2-like K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
E 107115206 NXF1; nuclear RNA export factor 1 K14284 NXF; nuclear RNA export factor
E 107114327 TDRD3; tudor domain containing 3 K18404 TDRD3; tudor domain-containing protein 3
E 107120495 LARP4B; La ribonucleoprotein domain family member 4B K18763 LARP4; la-related protein 4
E 107122514 LARP4; La ribonucleoprotein domain family member 4 K18763 LARP4; la-related protein 4
B mRNA degradation factors
C 5'-3' decay
D Decapping complex
E 107125423 DCP1A; decapping mRNA 1A K12610 DCP1A; mRNA-decapping enzyme 1A [EC:3.-.-.-]
E 107120234 DCP1B; decapping mRNA 1B K12611 DCP1B; mRNA-decapping enzyme 1B [EC:3.-.-.-]
E 107116680 DCP2; decapping mRNA 2 K12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62]
E 107124566 DDX6; DEAD-box helicase 6 K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7]
E 107114915 EDC3; enhancer of mRNA decapping 3 K12615 EDC3; enhancer of mRNA-decapping protein 3
E 107112767 EDC4; enhancer of mRNA decapping 4 K12616 EDC4; enhancer of mRNA-decapping protein 4
E 107117563 PATL1; PAT1 homolog 1, processing body mRNA decay factor K12617 PATL1; DNA topoisomerase 2-associated protein PAT1
D Lsm complex
E 107122031 LSM1; LSM1 homolog, mRNA degradation associated K12620 LSM1; U6 snRNA-associated Sm-like protein LSm1
E 107108245 LSM2; LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated K12621 LSM2; U6 snRNA-associated Sm-like protein LSm2
E 107125915 LSM3; LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3
E 107105738 LSM5; LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated K12624 LSM5; U6 snRNA-associated Sm-like protein LSm5
E 107120274 LSM6; LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6
E 107118491 LSM7; LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated K12626 LSM7; U6 snRNA-associated Sm-like protein LSm7
E 107113914 LSM8; LSM8 homolog, U6 small nuclear RNA associated K12627 LSM8; U6 snRNA-associated Sm-like protein LSm8
D 5' exonucleases
E 107112361 XRN1; 5'-3' exoribonuclease 1 K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]
E 107106120 XRN2; 5'-3' exoribonuclease 2 K12619 XRN2; 5'-3' exoribonuclease 2 [EC:3.1.13.-]
E 107108063 U8 snoRNA-decapping enzyme-like K16855 NUDT16; U8 snoRNA-decapping enzyme [EC:3.6.1.62 3.6.1.64]
D Other 5'-3' decay factors
E 107119892 DCPS; decapping enzyme, scavenger K12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59]
E 107119568 probable helicase with zinc finger domain K25168 HELZ; helicase with zinc finger domain [EC:5.6.2.-]
C 3'-5' decay
D Core exosome factors
E 107114440 EXOSC1; exosome component 1 K07573 CSL4; exosome complex component CSL4
E 107122769 EXOSC2; exosome component 2 K03679 RRP4; exosome complex component RRP4
E 107106376 EXOSC3; exosome component 3 K03681 RRP40; exosome complex component RRP40
E 107115300 EXOSC4; exosome component 4 K11600 RRP41; exosome complex component RRP41
E 107119234 EXOSC5; exosome component 5 K12590 RRP46; exosome complex component RRP46
E 107121794 EXOSC6; exosome component 6 K12587 MTR3; exosome complex component MTR3
E 107114801 EXOSC7; exosome component 7 K12589 RRP42; exosome complex component RRP42
E 107125575 EXOSC8; exosome component 8 K12586 RRP43; exosome complex component RRP43
E 107115398 EXOSC9; exosome component 9 K03678 RRP45; exosome complex component RRP45
D Exosome cofactors
E 107106601 DIS3; DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease K12585 DIS3; exosome complex exonuclease DIS3/RRP44 [EC:3.1.13.-]
E 107121190 DIS3L; DIS3 like exosome 3'-5' exoribonuclease K18681 DIS3L; DIS3-like exonuclease 1 [EC:3.1.13.-]
E 107108916 EXOSC10; exosome component 10 K12591 RRP6; exosome complex exonuclease RRP6 [EC:3.1.13.-]
E 107109830 MPHOSPH6; M-phase phosphoprotein 6 K12593 MPHOSPH6; M-phase phosphoprotein 6, animal type
E 107114667 probable ATP-dependent RNA helicase DDX60 K20103 DDX60; ATP-dependent RNA helicase DDX60 [EC:5.6.2.7]
E 107114668 DDX60; DExD/H-box helicase 60 K20103 DDX60; ATP-dependent RNA helicase DDX60 [EC:5.6.2.7]
D TRAMP complex
E 107117173 PAPD5; poly(A) RNA polymerase D5, non-canonical K03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5/7 [EC:2.7.7.19]
E 107123750 PAPD7; poly(A) RNA polymerase D7, non-canonical K03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5/7 [EC:2.7.7.19]
E 107114855 ZCCHC7; zinc finger CCHC-type containing 7 K12597 AIR1_2; protein AIR1/2
E 107120509 SKIV2L2; Ski2 like RNA helicase 2 K12598 MTR4; ATP-dependent RNA helicase DOB1 [EC:5.6.2.6]
D Ski complex
E 107105479 SKIV2L; Ski2 like RNA helicase K12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6]
E 107124696 TTC37; tetratricopeptide repeat domain 37 K12600 SKI3; superkiller protein 3
E 107121791 WDR61; WD repeat domain 61 K12602 WDR61; WD repeat-containing protein 61
D Ccr4-NOT complex
E 107118872 CNOT6L; CCR4-NOT transcription complex subunit 6 like K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
E 107123713 CNOT6; CCR4-NOT transcription complex subunit 6 K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
E 107125682 CCR4-NOT transcription complex subunit 1-like K12604 CNOT1; CCR4-NOT transcription complex subunit 1
E 107118551 CCR4-NOT transcription complex subunit 1 K12604 CNOT1; CCR4-NOT transcription complex subunit 1
E 107105708 CNOT2; CCR4-NOT transcription complex subunit 2 K12605 CNOT2; CCR4-NOT transcription complex subunit 2
E 107113135 CNOT3; CCR4-NOT transcription complex subunit 3 K12580 CNOT3; CCR4-NOT transcription complex subunit 3
E 107118904 CNOT4; CCR4-NOT transcription complex subunit 4 K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]
E 107115379 CNOT8; CCR4-NOT transcription complex subunit 8 K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E 107116758 CNOT7; CCR4-NOT transcription complex subunit 7 K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E 107114630 CNOT9; CCR4-NOT transcription complex subunit 9 K12606 RCD1; CCR4-NOT transcription complex subunit 9
E 107116495 CNOT10; CCR4-NOT transcription complex subunit 10 K12607 CNOT10; CCR4-NOT transcription complex subunit 10
D Pan complex
E 107126202 PAN2; PAN2 poly(A) specific ribonuclease subunit K12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4]
E 107105449 PAN3; PAN3 poly(A) specific ribonuclease subunit K12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3
D Other 3'-5' decay factors
E 107109308 PARN; poly(A)-specific ribonuclease K01148 PARN; poly(A)-specific ribonuclease [EC:3.1.13.4]
E 107111944 PNLDC1; PARN like, ribonuclease domain containing 1 K01148 PARN; poly(A)-specific ribonuclease [EC:3.1.13.4]
E 107120959 DHX36; DEAH-box helicase 36 K14442 DHX36; ATP-dependent RNA helicase DHX36 [EC:5.6.2.6]
E 107118593 BTG1; BTG anti-proliferation factor 1 K14443 TOB; protein Tob/BTG
E 107124389 protein BTG3-like K14443 TOB; protein Tob/BTG
E 107117158 TOB2; transducer of ERBB2, 2 K14443 TOB; protein Tob/BTG
E 107122116 BTG4; BTG anti-proliferation factor 4 K14443 TOB; protein Tob/BTG
E 107121893 protein BTG2-like K14443 TOB; protein Tob/BTG
E 107115528 protein BTG1-like K14443 TOB; protein Tob/BTG
E 107110024 TOB1; transducer of ERBB2, 1 K14443 TOB; protein Tob/BTG
E 107110787 NOCT; nocturnin K18764 NOCT; nocturnin [EC:3.1.3.108]
E 107122583 ERI1; exoribonuclease 1 K18416 THEX1; 3'-5' exoribonuclease 1 [EC:3.1.-.-]
E 107114580 ERI2; ERI1 exoribonuclease family member 2 K18417 ERI2; ERI1 exoribonuclease 2 [EC:3.1.-.-]
E 107119892 DCPS; decapping enzyme, scavenger K12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59]
E 107106849 PDE12; phosphodiesterase 12 K19612 PDE12; 2',5'-phosphodiesterase [EC:3.1.13.4 3.1.4.-]
E 107109146 IREB2; iron responsive element binding protein 2 K22416 IREB2; iron-responsive element-binding protein 2
E 107119568 probable helicase with zinc finger domain K25168 HELZ; helicase with zinc finger domain [EC:5.6.2.-]
E 107123517 HELZ2; helicase with zinc finger 2 K25165 HELZ2; 3'-5' exoribonuclease HELZ2 [EC:3.1.13.1 5.6.2.6]
E 107120538 NRDE2; NRDE-2, necessary for RNA interference, domain containing K26109 NRDE2; nuclear exosome regulator NRDE2
E 107107240 SAMD4A; sterile alpha motif domain containing 4A K27396 SMG; protein Smaug
E 107106945 SAMD4B; sterile alpha motif domain containing 4B K27396 SMG; protein Smaug
E 107108158 FOCAD; focadhesin K27498 FOCAD; focadhesin
C Other degradation factors
D RNases
E 107114979 ribonuclease-like K01168 RNASE1_2; pancreatic ribonuclease [EC:4.6.1.18]
E 107125989 ZC3H12C; zinc finger CCCH-type containing 12C K18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]
E 107114112 ZC3H12D; zinc finger CCCH-type containing 12D K18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]
E 107114222 ZC3H12B; zinc finger CCCH-type containing 12B K18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]
E 107110172 ZC3H12A; zinc finger CCCH-type containing 12A K18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]
#
AProkaryotic type
B Bacterial mRNA degradation factors
C RNA degradosome components
D Ribonucreases
E 107108371 DROSHA; drosha ribonuclease III K03685 rnc; ribonuclease III [EC:3.1.26.3]
E 107116300 REXO2; RNA exonuclease 2 K13288 orn; oligoribonuclease [EC:3.1.-.-]
D Helicases
D Other RNA degradosome components
E 107110275 ENO1; enolase 1 K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
E 107124431 ENO3; enolase 3 K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
E 107116799 ENO2; enolase 2 K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
E 107123655 PNPT1; polyribonucleotide nucleotidyltransferase 1 K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
E 107106684 PFKL; phosphofructokinase, liver type K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
E 107123964 PFKP; phosphofructokinase, platelet K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
E 107118971 PFKM; phosphofructokinase, muscle K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
C Other RNA degradation factors
D Chaperones
E 107106740 HSPA9; heat shock protein family A (Hsp70) member 9 K04043 dnaK; molecular chaperone DnaK
E 107124752 HSPD1; heat shock protein family D (Hsp60) member 1 K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D Others
D Bacterial Small RNA Regulators
B Archeal mRNA degradation factors
C Exosome components
D Core exosome
E 107122769 EXOSC2; exosome component 2 K03679 RRP4; exosome complex component RRP4
E 107114440 EXOSC1; exosome component 1 K07573 CSL4; exosome complex component CSL4
D Cofactors
E 107115300 EXOSC4; exosome component 4 K11600 RRP41; exosome complex component RRP41
E 107114801 EXOSC7; exosome component 7 K12589 RRP42; exosome complex component RRP42
D Others
!
#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: April 25, 2024