+D	Messenger RNA Biogenesis	KO
#<h2><a href="/kegg/brite.html"><img src="/Fig/bget/kegg3.gif" align="middle" border=0></a>&nbsp; Prokaryotic Defense System - Geobacter sulfurreducens PCA</h2>
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A<b>CRISPR-Cas system</b>
B  Universal Cas proteins
C    GSU0057 cas1-1_cas4; CRISPR-associated exonuclease Cas4 and endodeoxyribonuclease Cas1	K15342 cas1; CRISP-associated protein Cas1 
C    GSU1392 cas1-2; CRISPR-associated endodeoxyribonuclease Cas1	K15342 cas1; CRISP-associated protein Cas1 
C    GSU0058 cas2-1; CRISPR-associated endoribonuclease Cas2	K09951 cas2; CRISPR-associated protein Cas2 
C    GSU1393 cas2-2; CRISPR-associated endoribonuclease Cas2	K09951 cas2; CRISPR-associated protein Cas2 
B  Type I CRISPR-Cas system
C    Type I signiture cas proteins
D      GSU1384 cas3-2; CRISPR-associated helicase Cas3	K07012 cas3; CRISPR-associated endonuclease/helicase Cas3 [EC:3.1.-.- 5.6.2.4] 
D      GSU0051 cas3-1; CRISPR-associated helicase Cas3	K07012 cas3; CRISPR-associated endonuclease/helicase Cas3 [EC:3.1.-.- 5.6.2.4] 
C    Subtype I-A factors
C    Subtype I-B factors
C    Subtype I-C factors
C    Subtype I-D factors
C    Subtype I-E factors
D      GSU1385 cse1; CRISPR processing complex protein CasA	K19123 casA; CRISPR system Cascade subunit CasA 
D      GSU1386 cse2; CRISPR processing complex protein CasB	K19046 casB; CRISPR system Cascade subunit CasB 
D      GSU1387 cse4; CRISPR processing complex protein CasC	K19124 casC; CRISPR system Cascade subunit CasC 
D      GSU1388 cas5e; CRISPR processing complex protein CasD	K19125 casD; CRISPR system Cascade subunit CasD 
D      GSU1389 cse3; CRISPR processing complex protein CasE	K19126 casE; CRISPR system Cascade subunit CasE 
C    Subtype I-F factors
C    Subtype I-U factors
D      GSU0053 csb1; CRISPR-associated protein Csb1	K19131 csb1; CRISPR-associated protein Csb1 
D      GSU0054 csb2; CRISPR-associated protein Csb2	K19132 csb2; CRISPR-associated protein Csb2 
D      GSU0052 csx14; CRISPR-associated protein	K19135 csx14; CRISPR-associated protein Csx14 
B  Type II CRISPR-Cas system
C    Type II signiture cas proteins
C    Subtype II-A factors
C    Subtype II-B factors
B  Type III CRISPR-Cas system
C    Type III signiture cas proteins
C    Subtype III-A factors
C    Subtype III-B factors
C    Subtype III-U factors
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A<b>Restriction and modification system (R-M system)</b>
B  Type I R-M system
B  Type II R-M system
C    Restriction endonucleases
C    DNA methyltransferases
D      GSU0227 DNA methyltransferase, putative	K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] 
B  Type III R-M system
B  Type IV R-M system
C    GSU1365 type II restriction endonuclease, zinc finger	K07448 mrr; restriction system protein 
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A<b>Toxin-antitoxin system (TA system)</b>
B  Type I TA system
C    Hok-Sok
C    SymE-SymR
C    Ldr-Rdl
C    TisB-IstR
C    Ibs-Sib
C    ShoB-OhsC
C    RalR-RalA
B  Type II TA system
C    MazF-MazE
D      GSU0736 toxin, MazF family	K07171 mazF; mRNA interferase MazF [EC:3.1.-.-] 
C    ChpB-ChpS
C    YhaV-PrlF
C    RelE/StbE-RelB/StbD
D      GSU2439 toxin, RelE family	K06218 relE; mRNA interferase RelE/StbE 
D      GSU2438 antitoxin, Phd family	K18923 stbD; antitoxin StbD 
C    YafQ-dinJ
C    YoeB-YefM
C    HipA-HipB
D      GSU2399 HipA domain protein	K07154 hipA; serine/threonine-protein kinase HipA [EC:2.7.11.1] 
C    HicA-HicB
C    YafO-YafN
C    Hha-TomB
C    PspC-PspB
C    CcdB-CcdA
C    ParE-ParD
D      GSU1354 toxin, RelE family	K19092 parE1_3_4; toxin ParE1/3/4 
C    Doc-Phd
C    HigB-HigA
C    MqsR-MqsA
C    VapC-VapB
D      GSU2472 toxin, PIN family	K18828 mvpA; tRNA(fMet)-specific endonuclease VapC [EC:3.1.-.-] 
D      GSU2473 antitoxin, AbrB family	K18829 mvpT; antitoxin VapB 
C    PezT-PezA
C    YobL-YobK
C    YokI-YokJ
C    YqcG-YqcF
C    YxiD-YxxD
C    FitB-FitA
C    BC_0920-BC_0921
C    Type II TA system related factors
D      GSU3063 ftsZ; cell division protein FtsZ	K03531 ftsZ; cell division protein FtsZ 
D      GSU0733 mreB-2; cell shape-determining protein MreB	K03569 mreB; rod shape-determining protein MreB and related proteins 
D      GSU2089 mreB-1; cell shape-determining protein MreB	K03569 mreB; rod shape-determining protein MreB and related proteins 
D      GSU1219 gltX; glutamyl-tRNA synthetase, non-discriminating	K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] 
B  Type III TA system
C    AbiQ system
B  Type IV TA system
C    YeeV-YeeU
C    CptA-CptB
B  Type V TA system
C    GhoT-GhoS
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A<b>DNA phosphothiolation system</b>
B  Sulfur modification proteins
C    GSU2570 nifS-2; nitrogen fixation iron-sulfur cluster assembly cysteine desulfurase NifS	K04487 iscS; cysteine desulfurase [EC:2.8.1.7] 
C    GSU2011 nifS-1; nitrogen fixation iron-sulfur cluster assembly cysteine desulfurase NifS	K04487 iscS; cysteine desulfurase [EC:2.8.1.7] 
C    GSU2786 dndA; cysteine desulfurase	K04487 iscS; cysteine desulfurase [EC:2.8.1.7] 
B  DNA phosphorothioation-dependent restriction proteins
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#Last updated: November 7, 2023